scholarly journals The Potential Role of Cinnamon in Human Health

Forests ◽  
2021 ◽  
Vol 12 (5) ◽  
pp. 648
Author(s):  
Natalia Błaszczyk ◽  
Angelina Rosiak ◽  
Joanna Kałużna-Czaplińska
Keyword(s):  
Potential Role ◽  
Folk Medicine ◽  
Antibacterial Properties ◽  
Analytical Techniques ◽  
Biologically Active Compounds ◽  
Biologically Active ◽  
Active Compounds ◽  
Tropical Plant ◽  
Digestive Disorders

Cinnamon is an unusual tropical plant belonging to the Lauraceae family. It has been used for hundreds of years as a flavor additive, but it has also been used in natural Eastern medicine. Cinnamon extracts are vital oils that contain biologically active compounds, such as cinnamon aldehyde, cinnamic alcohol, cinnamic acid, and cinnamate. It has antioxidant, anti-inflammatory, and antibacterial properties and is used to treat diseases such as diabetes and cardiovascular disease. In folk medicine, cinnamon species have been used as medicine for respiratory and digestive disorders. Their potential for prophylactic and therapeutic use in Parkinson’s and Alzheimer’s disease has also been discovered. This review summarizes the available isolation methods and analytical techniques used to identify biologically active compounds present in cinnamon bark and leaves and the influence of these compounds in the treatment of disorders.

scholarly journals Expanding the chemical space of hydrophobic pharmacophores: the role of hydrophobic substructures in the development of novel transcription modulators

MedChemComm ◽  
2016 ◽  
Vol 7 (6) ◽  
pp. 1082-1092 ◽  
Author(s):  
Shinya Fujii
Keyword(s):  
Hydrophobic Interactions ◽  
Chemical Space ◽  
Pharmacokinetic Profile ◽  
Biologically Active Compounds ◽  
Biologically Active ◽  
Active Compounds

Interactions between biologically active compounds and their targets often involve hydrophobic interactions, and hydrophobicity also influences the pharmacokinetic profile.

A simple strategy for efficient preparation of networks based on poly(2-isopropenyl-2-oxazoline), poly(ethylene oxide), and selected biologically active compounds: Novel hydrogels with antibacterial properties

Soft Matter ◽  
2021 ◽  
Author(s):  
Bartosz Kopka ◽  
Bartłomiej Kost ◽  
Katarzyna Rajkowska ◽  
Andrzej Pawlak ◽  
Alina Kunicka-Styczyńska ◽  
...  
Keyword(s):  
Ethylene Oxide ◽  
Benzoic Acid ◽  
Polymer Networks ◽  
Antibacterial Properties ◽  
Biologically Active Compounds ◽  
Biologically Active ◽  
Active Compounds ◽  
Simple Strategy ◽  
Poly Ethylene Oxide ◽  
Poly Ethylene

Novel polymer networks composed of biocompatible, hydrophilic poly(2-isopropenyl-2-oxazoline), poly(ethylene oxide), and biologically active compounds (cinnamic acid, benzoic acid or eugenol) were developed for potential antimicrobial applications.

scholarly journals Pomegranate Fruit as a Rich Source of Biologically Active Compounds

2014 ◽  
Vol 2014 ◽  
pp. 1-12 ◽  
Author(s):  
Sreeja Sreekumar ◽  
Hima Sithul ◽  
Parvathy Muraleedharan ◽  
Juberiya Mohammed Azeez ◽  
Sreeja Sreeharshan
Keyword(s):  
Protective Role ◽  
Normal Breast ◽  
Biologically Active Compounds ◽  
Biologically Active ◽  
Osteoblastic Cell ◽  
Published Data ◽  
Active Compounds ◽  
Medicinal Properties ◽  
Pomegranate Fruit

Pomegranate is a widely used plant having medicinal properties. In this review, we have mainly focused on the already published data from our laboratory pertaining to the effect of methanol extract of pericarp of pomegranate (PME) and have compared it with other relevant literatures onPunica. Earlier, we had shown its antiproliferative effect using human breast (MCF-7, MDA MB-231), and endometrial (HEC-1A), cervical (SiHa, HeLa), and ovarian (SKOV3) cancer cell lines, and normal breast fibroblasts (MCF-10A) at concentration of 20–320 μg/mL. The expressions of selected estrogen responsive genes (PR, pS2, and C-Myc) were downregulated by PME. Unlike estradiol, PME did not increase the uterine weight and proliferation in bilaterally ovariectomized Swiss-Albino mice models and its cardioprotective effects were comparable to that of 17β-estradiol. We had further assessed the protective role of PME on skeletal system, using MC3T3-E1 cells. The results indicated that PME (80 μg/mL) significantly increased ALP (Alkaline Phosphatase) activity, supporting its suggested role in modulating osteoblastic cell differentiation. The antiosteoporotic potential of PME was also evaluated in ovariectomized (OVX) rodent model. The results from our studies and from various other studies support the fact that pomegranate fruit is indeed a source of biologically active compounds.

scholarly journals Дослідження інуліну в артишоку суцвіттях, заготовлених в Україні та Франції

2017 ◽  
Author(s):  
А. І. Fedosov ◽  
V. S. Kyslychenko ◽  
О. М. Novosel
Keyword(s):  
Plant Material ◽  
Folk Medicine ◽  
Mass Spectrometric ◽  
Biologically Active Compounds ◽  
Biologically Active ◽  
Spectrometric Method ◽  
Mass Spectrometric Method ◽  
Active Compounds ◽  
Quantitative Content ◽  
Dark Violet

Introduction. There are over 12 000 medicinal plants encountered nowadays which are a biogenetically formed complex of biologically active compounds (BAC) and are extensively used in scientific as well as folk medicine. The plants which are used as food products and contain a large number of biologically active compounds are of great importance. Artichoke (Cynara scolymus L.) from Asteraceae family belongs to the group of plants which due to the presence of different groups of BAC is widely used as cholagogue, hepatoprotective, diuretic, antisclerotic, anti-inflammatory, analgesic, hypoglycaemic agent. BAC of artichoke is represented by carbohydrates, hydroxycinnamic acids, flavonoids, essential oil etc.The aim of the study – identification and determination of the quantitative content of inulin in the artichoke inflorescences collected inUkraine andFrance.Methods of the research. The presence of inulin in the studied plant material was confirmed using the Molisch’s test. The quantitative content of inulin in the artichoke inflorescences was determined spectrophotometrically (method 1) and by the means of GC chromato-mass-spectrometric method (method 2).Results and Discussion. The appearance of the dark-violet coloring confirmed the presence of inulin in both samples of the plant material studied. The content of fructosanes’ sum, determined spectrophotometrically, was found to be 2.31 % in the artichoke inflorescences collected inUkraine, and 2.77 % in those collected inFrance. The content of inulin determined by the means of GC chromato-mass-spectrometry comprised 119.30 mg/ml and 147.60 mg/ml respectively.Conclusions. The presence of inulin was confirmed using the Molisch’s test in both samples of artichoke inflorescences.The content of inulin in the artichoke inflorescence collected inUkraineandFrancewas determined by the means of spectrophotometric and GC chromato-mass-spectrometric methods of analysis, and comprised 2.31% and 119.30 mg/ml respectively in the artichoke inflorescences collected inUkraine, and 2.77% and 147.60 mg/ml respectively in the artichoke inflorescences collected inFrance. The results obtained allow considering the plant material of artichoke of Ukrainian and French origin interchangeable for the biologically active substances obtaining. 

scholarly journals Role Of Copper For Human Organism

2011 ◽  
Vol 2 ◽  
Author(s):  
Sedrak Ghazaryan
Keyword(s):  
Biologically Active Compounds ◽  
Biologically Active ◽  
Human Organism ◽  
Biological Aspect ◽  
Active Compounds

The review focuses on a very peculiar aspect of the application of copper containing biologically active compounds of different chemical classes as have shown at the last scientific researches in the field of Cu (II) chelates, chelates possess have a higher activity of the same sort, than their mother compounds.The presented material shows essentially important qualities of Cu (II) containing compounds in biological aspect and has an interest for chemists, biochemists and pharmacologists.

Nickel(0)-Catalyzed Linear-Selective Hydroarylation of Unactivated Alkenes and Styrenes with Arylboron Acids

2018 ◽  
Author(s):  
Honggui Lv ◽  
Li-Jun Xiao ◽  
Dongbing Zhao ◽  
Qi-Lin Zhou
Keyword(s):  
Butyric Acid ◽  
Biologically Active Compounds ◽  
Biologically Active ◽  
Active Compounds ◽  
Highly Efficient ◽  
Organoboronic Acids

Herein, we realized the first linear-selective hydroarylation of unactivated alkenes and styrenes with organoboronic acids by introducing directing groupon alkenes. Our method is highly efficient and scalable, and provides a modular route to assemble structurally diverse alkylarenes, especially for γ-aryl butyric acid derivatives, which have been widely utilized as chemical feedstocks to access multiple marketed drugs, and biologically active compounds.<br>

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