scholarly journals Cheilospirura hamulosa in the Rock Partridge (Alectoris graeca saxatilis): Epidemiological Patterns and Prediction of Parasite Distribution in France

Diversity ◽  
2020 ◽  
Vol 12 (12) ◽  
pp. 484
Author(s):  
Angela Fanelli ◽  
Paolo Tizzani ◽  
Ezio Ferroglio ◽  
Eric Belleau

The rock partridge (Alectoris graeca saxatilis) is an alpine Galliform with high conservation value. Several factors, including parasitic helminths, play a role in population dynamics, and consequently in the conservation management of wild Galliformes. The aim of this study was to assess the epidemiological characteristics of Cheilospirura hamulosa (Nematoda, Acuarioidea) in the Rock partridge population in France. Machine learning modeling algorithms were applied to identify the environmental variables influencing parasite occurrence, and to map parasite presence probability. The present work is based on a long-term sampling (1987–2019) conducted in the French Alps. C. hamulosa was found with a prevalence (P) of 39% (Confidence Interval—CI 95%: 34–43), and mean intensity of 7.7 (7.8 sd). The highest prevalence (P: 67%, CI 95%: 54–80) was detected in the period 2005–2009. Latitude was the most important variable shaping the parasite distribution, followed by altitude, annual mean temperature, temperature seasonality, and the amount of precipitation of the coldest quarter. The area suitable for parasite presence included 73% of the French Alps. This work represents the first epidemiological surveillance on C. hamulosa infection in the rock partridge. It provides evidence of a high level of infection and identifies priority areas at higher infection risk, where a close monitoring of the rock partridge populations should be carried out.

Author(s):  
Ekaterina Peredelskaya ◽  
Tatyana Safyanova ◽  
Mikhail Druchanov

Chickenpox is an urgent problem, as it is widely spread with a high level of morbidity and an increasing share in the structure of the General infectious pathology with significant economic damage. The aim of the study is to study the epidemiological and clinical features of chickenpox in adults hospitalized in Krai government-owned publicy funded health care institution «City clinical hospital No. 5, Barnaul» for the period 2008‑2018. Content analysis included statistical reporting forms No. 2 of Federal state statistical supervision «Data on infectious and parasitic diseases» in the city of Barnaul during the period 2008‑2018 of medical archival documents adult infectious Department Krai government-owned publicy funded health care institution «City clinical hospital №5, Barnaul» for the same period. Data processing was performed using calculation of intensive and extensive indicators, calculation of the arithmetic mean (X) and standard error of the average (m). Calculations were made using the STATISTICA-10 program. Consistently high rates were recorded, with an average of 64.32 ± 3.46 per 100,000 population. The percentage of hospitalized adults averaged 18.5% during the study period. Adults aged 18‑30 were more likely to be admitted to the hospital (90.3%); 41.6% were students. Adults with moderate severity were hospitalized more often (70.6%); 7 patients (1.3%) had complications: aphthous stomatitis (3 cases), pustulosis (2 cases), and pneumonia (2 cases). Patients with severe severity of the disease accounted for 2.4%, the premorbid background was burdened in 48% (HIV infection, tuberculosis). In 35% of patients with severe severity, the final diagnosis of Herpes zoster was made, all patients older than 40 years, stayed in the hospital for 20‑25 days.


2014 ◽  
Vol 31 (2) ◽  
pp. 121-128
Author(s):  
Marina Kostić ◽  
Biljana Kocić ◽  
Nataša Rančić

Summary The aim of this paper was to determine the trend of diseases and epidemiological characteristics of viral antigen carrying of hepatitis B for better implementation of prevention and control of the disease activity. The annual reports, reports of diseases - deaths from infectious diseases, epidemiological survey of the Public Health Institute (IPH) Niš were used as the material. The period from 2002 to 2011 in the Nišava District was considered. A descriptive method was used. HBsAg carrying shows an upward trend (y=15+3.27 x). Most carriers are males (57.27%), live in urban areas (98.16/ 100.000 population), average age 41.92 years old ±SD 18.59, pensioners (22.42%). 54.05% are nephrology patients (almost all retirees under the age of 60 years old). Only 15.76% were hospitalized. The data on the vaccination status are insufficient. In 5.45%, co-infection with hepatitis C virus was found. 63.33% belong to the group of patients for whom there were no data on the mode of transmission. Hemodialysis patients make 16.67%, blood donors 9.39%, 6.36% pregnant women and injecting drug users 1.21%. The upward trend of carrying, the presence of all known risk groups in the population of carrying in the Nišava District points to the need for improved epidemiological surveillance, strict application of protective measures, conducting of statutory vaccination of all categories of people exposed to particular risk of infection as well as continuing education on preventive measures of both population and health care providers.


2009 ◽  
Vol 2009 ◽  
pp. 1-6 ◽  
Author(s):  
Pejvak Khaki ◽  
Preena Bhalla ◽  
Ahmad Mir Fayaz ◽  
Sohiela Moradi Bidhendi ◽  
Majid Esmailzadeh ◽  
...  

Control and preventive measures for gonococcal infections are based on precise epidemiological characteristics ofN. gonorrhoeaeisolates. In the present study the potential utility of opa-typing and ribotyping for molecular epidemiological study of consecutive gonococcal strains was determined. Sixty gonococcal isolates were subjected to ribotyping with two restriction enzymes,AvaII andHincII, and opa-typing withTaqI andHpaII for epidemiological characterization of gonococcal population. Ribotyping withAvaII yielded 6 ribotype patterns while twelve RFLP patterns were observed withHincII. Opa-typing of the 60 isolates revealed a total 54 opa-types, which 48 were unique and 6 formed clusters. Fifty-two opa-types were observed withTaqI-digested PCR product while opa-typing withHpaII demonstrated 54 opa-types. The opa-types from isolates that were epidemiologically unrelated were distinct, whereas those from the sexual contacts were identical. The results showed that opa-typing is highly useful for characterizing gonococcal strains from sexual contacts and has more discriminatory than ribotyping that could differentiate between gonococci of the same ribotype. The technique even with a single restriction enzyme has a high level of discrimination (99.9%) between epidemiologically unrelated isolates. In conclusion, the molecular methods such as opa-typing and ribotyping can be used for epidemiological characterization of gonococcal strains.


2020 ◽  
Author(s):  
Hongxin Li ◽  
Lin Zhou ◽  
Yong Zhao ◽  
Lijuan Ma ◽  
Xiaoyan Liu ◽  
...  

Abstract Background: Group A streptococcus (GAS) is an important human pathogen responsible for a broad range of infections. Epidemiological surveillance has been crucial to detect changes in the geographical and temporal variation of the disease pattern. The objective of this study was to investigate the molecular epidemiological characteristics and antimicrobial resistance of GAS isolates from patients in Children’s Hospital in Beijing. Methods: From 2016 to 2017, pharyngeal swab samples were collected from the outpatients in Children’s Hospital, Capital Institute of Pediatrics, who were diagnosed with scarlet fever. Antimicrobial susceptibility test was performed according to the distribution of conventional antibiotics and Clinical and Laboratory Standards Institute (CLSI) recommendations. The distribution of the macrolide-resistance genes ( ermB, ermA, mefA ), emm (M protein-coding gene) typing, and superantigens (SAg) gene profiling were examined by polymerase chain reaction (PCR). Results: A total of 297 GAS isolates were collected. The susceptibility of the isolates to penicillin, ceftriaxone, and levofloxacin was 100%. The resistance rate to erythromycin and clindamycin was 98.3% and 96.6%, respectively. The dominant emm types were emm12 (65.32%), emm1 (27.61%), emm75 (2.69%), and emm89 (1.35%). Of the 297 isolates, 290 (97.64%) carried the ermB gene, and 5 (1.68%) carried the mefA gene, while none carried the ermA gene. The most common superantigen genes identified from GAS isolates were smeZ (96.97%) , speC (92.59%), speG (91.58%), ssa (85.52%), speI (54.55%), speH (52.19%), and speA (34.34%). Isolates with the genotype emm1 possessed speA , speC , speG , speJ , speM , ssa , and smeZ , while emm12 possessed speC , speG , speH , speI , speM , ssa , and smeZ superantigens. Conclusions: The prevalent strain of GAS isolates in Beijing has a high resistance rate to macrolides; however, penicillin can still be the preferred antibiotic for treatment. Erythromycin resistance was predominantly mediated by ermB. The common emm types were emm12 and emm1. There was a correlation between emm and the superantigen gene. Thus, long-term monitoring and investigation of the emm types and superantigen genes of GAS prevalence are imperative.


2021 ◽  
Author(s):  
Anne-Laure Ferchaud ◽  
Claire Merot ◽  
Eric Normandeau ◽  
Ioannis Ragoussis ◽  
Charles Babin ◽  
...  

Despite the commercial importance of Greenland Halibut (Reinhardtius hippoglossoides), important gaps still persist in our knowledge of this species, including its reproductive biology and sex determination mechanism. In this study, we combined single molecule sequencing of long reads (Pacific Sciences) with Chromatin Conformation Capture sequencing (Hi-C) data to provide the first chromosome-level genome reference for this species. The high-quality assembly encompassed more than 598 Megabases (Mb) assigned to 1 594 scaffolds (scaffold N50 = 25 Mb) with 96 % of its total length distributed among 24 chromosomes. The investigation of its syntenic relationships with other economically important flatfish species revealed a high conservation of synteny blocks among members of this phylogenetic clade. Sex determination analysis revealed that flatfishes do not escape the rule applied to other teleost fish and exhibit a high level of plasticity and turnover in sex-determination mechanisms. A whole-genome sequence analysis of 198 individuals allowed us to draw a full picture of the molecular sex determination (SD) system for Greenland Halibut, revealing that this species possesses a very nascent male heterogametic XY system, with a putative major effect of the sox2 gene, also described as the main SD driver in two other flatfishes. Interestingly, our study also suggested for the first time in flatfishes that a putative Y-autosomal fusion could be associated with a reduction of recombination typical of early steps of sex chromosome evolution.


2021 ◽  
Author(s):  
Ayako Matsuda ◽  
Kei Asayama ◽  
Taku Obara ◽  
Naoto Yagi ◽  
Takayoshi Ohkubo

Abstract Background: Few reports have longitudinally investigated seasonal influenza epidemiological surveillance data of pediatric populations in the metropolitan areas of Japan. We aimed to provide descriptive characteristics of circulating influenza and to investigate the usefulness of setting thresholds for influenza in children (0–15 years old) in two satellite cities of a metropolitan area of Tokyo, Japan, for five consecutive seasons of the influenza epidemic.Methods: The survey was conducted annually during the influenza season, from 2014 to 2018 (ending March 2019), at preschools (kindergartens and nursery schools), elementary schools, and junior high schools located in Toda and Warabi cities, Saitama prefecture. We investigated the epidemiological characteristics and established thresholds using the World Health Organization method.Results: Of the 108,362 children (21,024 to 22,088 throughout five seasons) who received the questionnaire, 76,753 (70.8%; 14,652 to 15,808) responded. After exclusion of responses without basic information, 64,586 children were included in the analysis, of which 13,754 (21.3%) had tested positive for influenza. Influenza type A was generally dominant, whereas type B was responsible for a substantial share of all influenza cases (>40% in seasons 2015 and 2017, when type A circulated with low incidence). The weeks when the influenza epidemic peaked had no clear seasonal pattern among the surveyed years, i.e., the peaks appeared at week 51 (mid-December) or later, whereas the World Health Organization methods reported that the median period when a peak was observed was at 3 weeks (mid-January), regardless of school age group.Conclusions: The present information obtained from the epidemiological survey regarding seasonal influenza in children would be useful for general practitioners, health policymakers, and planners who establish prevention and control methods against influenza.


BMJ Open ◽  
2019 ◽  
Vol 9 (5) ◽  
pp. e027245 ◽  
Author(s):  
Alexis Sentís ◽  
Mario Martin-Sanchez ◽  
Maider Arando ◽  
Martí Vall ◽  
María Jesus Barbera ◽  
...  

ObjectivesYoung people are a critical target group for sexually transmitted infections (STI) surveillance due to their particular behavioural and social related vulnerability. The aim of this study was to describe the epidemiological characteristics and trends in the incidence of gonorrhoea, syphilis, HIV and venereal lymphogranuloma (LGV) among 15–24-year-olds in Barcelona, and to determine factors associated with HIV coinfection.DesignWe performed a population-based incidence study covering the 2007–2015 period.ParticipantsAll new cases of STI—HIV, gonorrhoea, infectious syphilis and LGV—notified to the epidemiological surveillance system in Barcelona between 2007 and 2015. 1218 cases were studied: 84.6% were men, 19.3% were 15–19 years old and 50.6% were born in Spain. Among men, 73.7% were men who have sex with men (MSM); among women, 85.6% were women that have sex with men.Primary and secondary outcomesIncidence of HIV, gonorrhoea, infectious syphilis and LGV. HIV coinfection.ResultsThere was an increase in the incidence of gonorrhoea, from 1.9 cases per 10 000 people in 2007 to 7.6/10 000 in 2015 (p<0.01), in MSM from 27.1 to 228.8/10 000 (p<0.01). The incidence of syphilis increased from 0.4/10 000 in 2007 to 3.1/10 000 in 2015 (significant in men only, p<0.01), in MSM from 18.1 to 116.9/10 000 (p<0.01). The incidence of HIV showed a non-significant increase in men (p=0.27), and that of LGV remained stable (p=0.59). Factors associated with increased risk of HIV coinfection included being MSM (adjusted OR[ORa]=14.14, 95% CI 3.34 to 59.91) and having >10 sexual partners (ORa=4.11, 95% CI 1.53 to 11.01) or STI diagnosis during the previous 12 months (ORa=2.06; 95% CI 1.13 to 3.77).ConclusionsThe incidence of gonorrhoea and syphilis among 15–24-year-olds increased, while HIV infection remained stable but with a high incidence among MSM. Being MSM, having sex with multiple partners and having a diagnosis of an STI in the previous 12 months were factors associated with HIV coinfection.


2019 ◽  
Vol 12 ◽  
pp. 117863611984036 ◽  
Author(s):  
Alberto Arnedo-Pena ◽  
Maria Angeles Romeu-Garcia ◽  
Noemi Meseguer-Ferrer ◽  
Iraya Vivas-Fornas ◽  
Ana Vizcaino-Batllés ◽  
...  

Background: Tuberculosis (TB) incidence remains low in health departments of Castellon and La Plana-Vila-real, but TB elimination is challenging. The objective of this study was to estimate associated factors of pulmonary tuberculosis (PTB) compared with extrapulmonary tuberculosis (ETB) and investigate epidemiological characteristics of these pathologies to orient control and prevention actions. Materials and Methods: A prospective case-case study was implemented by comparing PTB and ETB incidences during 2013-2016 from notification reports, epidemiological surveillance, and microbiological results of hospitals’ laboratories Hospital General Castellon and La Plana-Vila-Real in the province of Castellon of Valencia region in Spain. In this design, cases were patients with PTB and controls were patients with ETB. Directed acyclic graph approach was used for selection of potential risk and confounding factors. Adjusted odds ratios (AORs) were estimated by logistic regression models. Results: The study included 136 patients with PTB and 57 patients with ETB, with microbiological confirmation of 93.4% and 52.6%, and the annual median of incidence rates were 7.5 and 3.1 per 100 000 inhabitants, respectively. In general, patients with PTB were younger with higher male proportion than patients with ETB. Risk factors of PTB were smoking tobacco (AOR = 3.98; 95% confidence interval [CI] = 1.66-9.56), social problems (social marginalization, homeless, residence in shelters for the poor, or stay in prison) (AOR = 3.39; 95% CI = 1.05-10.94), and contact with patients with TB (AOR = 2.51; 95% CI = 1.06-5.95). No-smoking tobacco and no-drug abuse interaction decrease PTB risk (AOR = 0.27; 95% CI = 0.12-0.64). From these results, specific measures of health promotion and prevention can be addressed. Conclusions: The estimated associated factors of PTB may be prevented, and it was demonstrated that the case-case design is useful in the study of TB.


2020 ◽  
Author(s):  
Hongxin Li ◽  
Lin Zhou ◽  
Yong Zhao ◽  
Lijuan Ma ◽  
Xiaoyan Liu ◽  
...  

Abstract Background: Group A streptococcus (GAS) is an important human pathogen responsible for a broad range of infections. Epidemiological surveillance has been crucial to detect changes in the geographical and temporal variation of the disease pattern. The objective of this study was to investigate the molecular epidemiological characteristics and antimicrobial resistance of GAS isolates from patients in Children’s Hospital in Beijing. Methods: From 2016 to 2017, pharyngeal swab samples were collected from the outpatients in Children’s Hospital, Capital Institute of Pediatrics, who were diagnosed with scarlet fever. Antimicrobial susceptibility test was performed according to the distribution of conventional antibiotics and Clinical and Laboratory Standards Institute (CLSI) recommendations. The distribution of the macrolide-resistance genes (ermB, ermA, mefA), emm (M protein-coding gene) typing, and superantigens (SAg) gene profiling were examined by polymerase chain reaction (PCR). Results: A total of 297 GAS isolates were collected. The susceptibility of the isolates to penicillin, ceftriaxone, and levofloxacin was 100%. The resistance rate to erythromycin and clindamycin was 98.3% and 96.6%, respectively. The dominant emm types were emm12 (65.32%), emm1 (27.61%), emm75 (2.69%), and emm89 (1.35%). Of the 297 isolates, 290 (97.64%) carried the ermB gene, and 5 (1.68%) carried the mefA gene, while none carried the ermA gene. The most common superantigen genes identified from GAS isolates were smeZ (96.97%), speC (92.59%), speG (91.58%), ssa (85.52%), speI (54.55%), speH (52.19%), and speA (34.34%). Isolates with the genotype emm1 possessed speA, speC, speG, speJ, speM, ssa, and smeZ, while emm12 possessed speC, speG, speH, speI, speM, ssa, and smeZ superantigens. Conclusions: The prevalent strain of GAS isolates in Beijing has a high resistance rate to macrolides; however, penicillin can still be the preferred antibiotic for treatment. Erythromycin resistance was predominantly mediated by ermB. The common emm types were emm12 and emm1. There was a correlation between emm and the superantigen gene. Thus, long-term monitoring and investigation of the emm types and superantigen genes of GAS prevalence are imperative.


2018 ◽  
Vol 12 (1) ◽  
pp. 137 ◽  
Author(s):  
Rosangela Maria Ricardo Marchezini ◽  
Dilma Aparecida Machado de Oliveira ◽  
Luiz Jorge Fagundes ◽  
Suely Itsuko Ciosak

RESUMOObjetivo: analisar a ocorrência das IST/Aids em serviço de Dermatologia Sanitária. Método: estudo quantitativo, ecológico, retrospectivo, descritivo e exploratório sobre as IST diagnosticadas no serviço, no período de três anos, a partir das fichas de atendimento/prontuário e a de notificação compulsória. Os dados foram armazenados em planilha Excel e apresentados em tabelas de frequência. Resultados: foram analisados os prontuários de 8560 usuários atendidos, sendo que 379 apresentaram IST de notificação compulsória. Em três anos, dobrou o número de notificações. Predominou o sexo masculino (93,1%), adultos jovens (menos de 40 anos) e raça branca (75,2%). Houve equivalência entre os heterossexuais, homo e bissexuais, todos com elevado nível de escolaridade (50,4% com ensino médio e 23%, o universitário). As doenças de maior ocorrência foram: a sífilis (48,6%), mais frequente em homossexuais; tricomonas (18,4%); Aids (14,8%) e 12 gonorreias (14,6 %), maior incidência em heterossexuais. O HPV esteve presente em 500 usuários. Conclusão: as IST vêm aumentado no decorrer dos anos, com importante mudança no perfil da população. É premente a inclusão das ações de prevenção das IST de forma precoce na educação e atendimento à saúde. Descritores: Infecções Sexualmente Transmissíveis; Atenção Básica; Vigilância Epidemiológica; Enfermagem; Prevenção; Promoção.ABSTRACTObjective: to analyze the occurrence of STI / AIDS in the service of Sanitary Dermatology. Method: quantitative, ecological, retrospective, descriptive and exploratory study on the STIs diagnosed in the service, in the period of three years, from the records of attendance / medical records and the compulsory notification. The data was stored in an Excel spreadsheet and presented in frequency tables. Results: the medical records of 8560 users were analyzed, of which 379 presented STIs with compulsory notification. In three years, the number of notifications doubled. Prevalence was of male sex (93.1%), young adults (less than 40 years) and white (75.2%). There was an equivalence between heterosexuals, homosexuals and bisexuals, all with a high level of schooling (50.4% with high school and 23%, university). The most frequent diseases were: syphilis (48.6%), more frequent in homosexuals; trichomonas (18.4%); AIDS (14.8%) and 12 gonorrhea (14.6%), a higher incidence in heterosexuals. HPV was present in 500 users. Conclusion: STIs have increased over the years, with important changes in the population profile. It is urgent to include the actions of prevention of STIs in an early manner in education and health care. Descriptors: Sexual Transmitted Infection; Basic Attention; Epidemiological Surveillance; Nursing; Prevention; Promotion.RESUMENObjetivo: analizar la ocurrencia de las IST / SIDA en servicio de Dermatología Sanitaria. Método: estudio cuantitativo, ecológico, retrospectivo, descriptivo y exploratorio sobre las IST diagnosticadas en el servicio, en el período de tres años, a partir de las fichas de atención / prontuario y la de notificación obligatoria. Los datos se almacenaron en la hoja de cálculo de Excel y se mostraron en tablas de frecuencia. Resultados: se analizaron los prontuarios de 8560 usuarios atendidos, siendo que 379 presentaron IST de notificación obligatoria. En tres años, se duplicó el número de notificaciones. Se predijo el sexo masculino (93,1%), adultos jóvenes (menos de 40 años) y raza blanca (75,2%). Se observó una equivalencia entre los heterosexuales, homo y bisexuales, todos con elevado nivel de escolaridad (50,4% con enseñanza media y 23%, el universitario). Las enfermedades de mayor ocurrencia fueron: la sífilis (48,6%), más frecuente en homosexuales, tricomonas (18,4%); Sida (14,8%) y 12 gonorrea (14,6%), mayor incidencia en heterosexuales. El HPV estuvo presente en 500 usuarios. Conclusión: las IST han aumentado en el transcurso de los años, con un importante cambio en el perfil de la población. Es urgente la inclusión de las acciones de prevención de las IST, de forma precoz en la educación y atención a la salud. Descriptores: Infecciones Sexualmente Transmisibles; Atención Básica; Vigilancia Epidemiológica; Enfermería; Prevención; Promoción.


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