Neuroendocrine tumors in patients of the medical examination group

The article presents data on the level and structure of neuroendocrine tumors in a group of patients under observation bythe Central Military Clinical Hospital named after Mandrykа P.V. of the Ministry of Defense of the Russian Federation. Information about gender and age characteristics of the group of patients is provided.

OUTCOMES OF CONGENITAL HEART DISEASE IN NEWBORNS AT LVIV REGIONAL CLINICAL HOSPITAL, LVIV, UKRAINE

Introduction. Congenital abnormalities are the most common medical and social problems and the primary cause of fetal loss and children’s disability in the World, and particularly in Ukraine. In Ukraine, about 5 thousand children with congenital heart disease (CHD) are born every year. Up to date, information on the future of patients who received medical care for CHD was not systematized and often remains unavailable. The aim of the study: To perform a survey of women who gave birth to children with CHD and collect information about distant health outcomes. Methods. The medical history files of 170 children born with CHD in Lviv Regional Clinical Hospital, Lviv, Ukraine between 2011-2015 were selected. The criterion for inclusion in the group was a clinical diagnosis ''Congenital malformations of the circulatory system'' based on International Classification of Diseases-10 (Q20 - Q28). Results. According to the medical history files analysed in our study, among 170 children born with CHD, heart defects were detected at the prenatal stage in 67 patients (39.4%). Urgent surgical intervention was performed in 32 (18.6%) children.

Imaging and diagnostic accuracy of outpatient and inpatient hysteroscopy

Aim. To compare the results of visualisation and diagnostic accuracy during outpatient and inpatient hysteroscopy in women with endometrial disease.Materials and Methods. We performed a retrospective analysis of patients with uterine diseases who underwent outpatient hysteroscopy at Kemerovo City Clinical Hospital №4 (n = 300) or inpatient hysteroscopy within the hospitals (n = 300) in Kemerovo from 2018 to 2020. Confirmation of endometrial disease was carried out by manual vacuum aspiration.Results. Indications, imaging, and diagnostic accuracy did not differ for most endometrial diseases in outpatient and inpatient hysteroscopy, yet inpatient hysteroscopy was the option of choice in women with infertility (p = 0.035). Diagnostic accuracy of outpatient and inpatient hysteroscopy was highly concordant, albeit outpatient hysteroscopy more often revealed adenomyosis and uterine malformation and less often identified endometrial polyps.Conclusion. Outpatient and inpatient hysteroscopy are equally efficient, although outpatient hysteroscopy has its benefits in detecting adenomyosis and uterine malformation and be less informative in diagnosing endometrial polyps.

Analysis of lethal cases of pneumonia caused by SARS-CoV-2 virus according to the data of pathology department of Kharkiv Regional Clinical Hospital for the first half of 2021

Background. Given the great medical, social and economic significance of clinical research, pathogenesis and epidemiology of coronavirus infection, it is important to study the epidemiological and pathomorphological features of this infection in Ukraine, especially in fatal cases of this disease. Objective: to analyze the lethal cases of pneumonia caused by SARS-CoV-2 in comparison with lethal cases of pneumonia of other etiologies according to the pathology department of Kharkiv Regional Clinical Hospital for the first half of 2021. Methods. The material of this study was the observation of an autopsy from the archival material the pathology department of Kharkiv Regional Clinical Hospital. The study of autopsy protocols took into account the seasonality of the disease, sex and age of the deceased, the number of bed-days, data of clinical diagnosis and coincidences of pathological diagnosis, as well as the ICD code. 256 protocols of pathological examinations for the first half of 2021 were studied. Results. Of the 256 deaths from pneumonia of various etiologies, 201 (78.52%) were caused by SARS-CoV-2 infection. The highest number of deaths from pneumonia was registered in March, April and May 2021. The number of deaths of patients aged 18-44 years was 4.3% of the total, 45-59 years – 13.28%, 60-74 years – 47.27%, 75-90 years – 35.16%. The study sample among patients died of pneumonia caused by SARS-CoV-2 was dominated by women (57.42%, 147 cases), the number of men was 42.58% (109 cases). The direct causes of death were pulmonary-heart failure, multiple organ failure, acute pulmonary insufficiency, chronic pulmonary insufficiency, and pulmonary embolism. Conclusion. The obtained data can be useful for the analysis of regional features of epidemiology and pathogenesis of coronavirus disease in eastern Ukraine.

Professor Volodymyr Zemskov — a world-renowned Ukrainian surgeon

The article describes the professional and scientific way of professor Volodymyr Serhiyovych Zemskov, a prominent Ukrainian surgeon and a founder of the Kyiv Center for Liver, Bile Ducts and Pancreas Surgery which is currently based in the Kyiv City Clinical Hospital No10. The article presents the memories of his students and contemporaries, the facts about his professional biography and career development. The paper describes the main scientific interests of Volodymyr Zemskov, his achievements and scientific work.

Particularities of Surgical Treatment for the Neuropathic Diabetic Foot

Diabetic neuropathy is one of the chronic complications of diabetes and along with other complications causes a pathology called diabetic foot. The present study analyzed a group of 164 patients admitted to the surgery department of the Clinical Hospital “Doctor Ioan Cantacuzino” Bucharest, between September and December 2019. The results of the study highlight the potential for contamination of neuropathic lesions and the need for curative surgery, most conservative. The conclusion of the analysis emphasizes that the imbalance of the underlying disease changes, in a negative sense, the prognosis of any complication of it.

EPIDEMIOLOGICAL ASPECTS OF ACUTE APPENDICITIS ACCORDING TO THE CENTRAL CITY CLINICAL HOSPITAL OF ALMATY

В статье проанализировано 1759 случаев острого аппендицита по данным историй болезней пациентов, проходивших лечение на базе Центрального городской клинической больницы с 2015 по 2017 гг. Выявлены основные эпидемиолгические аспекты данной патологии. The article analyzes 1759 cases of acute appendicitis according to the case histories of patients treated at the Central City Clinical Hospital from 2015 to 2017. The main epidemiological aspects of this pathology have been identified.

USE OF EFFERENT THERAPY METHODS IN THE TREATMENT OF DESTRUCTIVE PANCREATITIS

Своевременное включение методов эфферентной терапии (гемодиафильтрация, плазмаферез) в комплексную интенсивную терапию сепсиса и септического шока у больных с острым деструктивным панкреатитом, находящихся на стационарном лечении в ЦГКБ г. Алматы, позволило быстро стабилизировать гемодинамику, респираторные нарушения и отказаться от применения адреномиметиков, а также значительно уменьшить клинические проявления тяжелой интоксикации, гипоксии и эндотоксикоза. Timely inclusion of efferent therapy methods (hemodiafiltration, plasmapheresis) in the complex intensive therapy of sepsis and septic shock in patients with acute destructive pancreatitis who are inpatient treatment at the Central city clinical hospital in Almaty, made it possible to quickly stabilize hemodynamics, respiratory disorders and abandon the use of adrenomimetics, as well as significantly reduce the clinical manifestations of severe intoxication, hypoxia and endotoxicosis.

FEATURE OF SURGICAL TREATMENT OF GASTRODUODENAL BLEEDING

Применение принципов комплексного использования эндоскопического гемостаза и использование эрадикационной, антисекреторной терапии у больных с гастродуоденальным кровотечением, находящихся на стационарном лечении в ЦГКБ г. Алматы, позволило улучшить результаты лечения больных, значительно снизить количество осложнений после операций, сократить частоту как общей, так и послеоперационной летальности. The application of the principles of the integrated use of endoscopic hemostasis and the use of eradication, antisecretory therapy in patients with gastroduodenal bleeding who are inpatient treatment at the Central City Clinical Hospital of Almaty, made it possible to improve the results of treatment of patients, significantly reduce the number of complications after surgery, and reduce the incidence of both general and postoperative mortality.