scholarly journals Detection of Neurological and Ophthalmological Pathologies with Optical Coherence Tomography Using Retinal Thickness Measurements: A Bibliometric Study

2020 ◽  
Vol 10 (16) ◽  
pp. 5477
Author(s):  
F. Javier Povedano-Montero ◽  
Robert N. Weinreb ◽  
Isidoro Raga-Martínez ◽  
Alejandro Romero ◽  
Francisco López-Muñoz

We carry out a bibliometric analysis on neurological and ophthalmological pathologies based on retinal nerve fiber layer (RNFL) thickness measured with optical coherence tomography (OCT). Documents were selected from Scopus database. We have applied the most commonly used bibliometric indicators, both for production and dispersion, as Price’s law of scientific literature growth, Lotka’s law, the transient index, and the Bradford model. Finally, the participation index of the different countries and affiliations was calculated. Two-hundred-and-forty-one documents from the period 2000–2019 were retrieved. Scientific production was better adjusted to linear growth (r = 0.88) than exponential (r = 0.87). The duplication time of the documents obtained was 5.6 years. The transience index was 89.62%, which indicates that most of the scientific production is due to very few authors. The signature rate per document was 5.2. Nine journals made up the Bradford core. USA and University of California present the highest production. The most frequently discussed topics on RNFL thinning are glaucoma and neurodegenerative diseases (NDD). The growth of the scientific literature on RNFL thickness was linear, with a very high rate of transience, which indicates low productivity and the presence of numerous authors who sporadically publish on this topic. No evidence of a saturation point was observed. In the last 10 years, there has been an increase in documents relating the decline of RNFL to NDD.

2021 ◽  
Vol 4 (1) ◽  
pp. 152-172
Author(s):  
Francisco López-Muñoz ◽  
Francisco J. Povedano-Montero ◽  
Alejandro Romero ◽  
Javier Egea ◽  
Cecilio Alamo

Melatonin is a molecule that has attracted a great deal of attention from the scientific community in the last 50 years. The aim of this study is to analyze the scientific production on related to melatonin using bibliometric tools. We performed a search in Web of Science, involving documents published between 1958 and 2019. We used bibliometric indicators to explore documents production, dispersion, distribution, time of duplication and annual growth, as Price's law of scientific literature growth, Lotka's law, the transient index and the Bradford model. We also calculated the participation index of the different countries and institutions. Finally, through bibliometric mapping, we explored the co-occurrence networks for the most frequently used terms in melatonin research. A total of 20,768 documents were retrieved. Scientific production was better adjusted to linear growth (r = 0.9535) than exponential (r = 0.9313). The duplication time of the documents obtained was 14.2 years. The transience index was 62%, which indicates that most of the scientific production is due to very few authors. The signature rate per document was 1.95. Thirty-four journals made up the Bradford core, highlighting Journal of Pineal Research. USA and University of Texas present the highest production. Map network visualization shows the generated term map detailing on clusters of closely related terms. The growth of the scientific literature on melatonin was linear, with a very high rate of transience, which indicates the presence of numerous authors who sporadically publish on this topic. No evidence of a saturation point was observed. In the last 10 years, there has been a relevant increase in documents on melatonin.


2020 ◽  
Vol 17 (2) ◽  
pp. 156-169
Author(s):  
Camille Elaine Zabala ◽  
Jubaida Mangondato-Aquino ◽  
Jose Ma. Martinez ◽  
John Mark De Leon

Purpose: To determine mean macular and retinal nerve fiber layer (RNFL) thickness of myopic Filipinos using spectral domain optical coherence tomography (SD-OCT) and to evaluate influence of age, gender, and degree of myopia. Design: Observational clinic-based cohort. Methods: Participants were divided into two groups: low-moderate myopia [spherical equivalent (SE) -0.50 D to -6.00 D] and high-pathologic myopia (SE < -6.00 D and AL > 26.5 mm). Subgroup analyses between low myopia (refraction < -3.00 D or less) and moderate myopia (> -3.00 D to -6.00 D), and high myopia (> -6.00 D to -8.00 D) and pathologic myopia (more than -8.00 D) were done. Macular and RNFL thickness were measured by a SD-OCT and axial length (AL) with non-contact biometry. Results: Of 156 eyes, 88/156 (56%) had low-moderate myopia, 68/156 (44%) had high-pathologic myopia. There were 67/156 (43%) male and 89/156 (57%) female subjects. Mean central foveal subfield thickness measurements were 264 ± 24 μm for low myopia, 258 ± 17 μm for moderate myopia, 253 ± 25 μm for high myopia, and 218 ± 48 μm for pathologic myopia. Mean RNFL thickness measurements were 105.62 ± 3.89 μmfor low myopia, 97.6 ± 2.45 μm for moderate myopia, 85.9 ± 3.87 μm for high myopia, and 75.14 ± 3.89 μm for pathologic myopia. Average SE (p < 0.0001) decreased while AL (p < 0.0001) increased with more myopia. Myopia and age significantly affected macular and RNFL thickness parameters except for the following where only the degree of myopia was a significant factor: central foveal, temporal parafoveal, nasal perifoveal, inferior and nasal RNFL thicknesses. Conclusion: Retinal SD-OCT thickness measurements decreased with increasing level of myopia and age. Central foveal, temporal parafoveal, nasal perifoveal, inferior and nasal RNFL thicknesses may be more appropriate SD-OCT parameters among myopic Filipino patients to monitor for glaucoma since they may be less influenced by age.


2011 ◽  
Vol 04 (01) ◽  
pp. 12 ◽  
Author(s):  
Elaine To ◽  
Dennis Lam ◽  
Christopher Kai-shun Leung ◽  
◽  
◽  
...  

High-speed, high-resolution imaging of the retinal nerve fiber layer (RNFL) with spectral-domain optical coherence tomography (OCT) has become an essential tool for evaluation of glaucoma. The Cirrus HD-OCT (Carl Zeiss Meditec, Inc. Dublin, CA) is a spectral-domain OCT that provides visualization of the distribution pattern and measurement of RNFL abnormalities in a 6x6mm2optic disc region. Analysis of the RNFL thickness deviation map—a color-coded map displaying areas of RNFL abnormalities—detects glaucoma with high sensitivity and specificity. Trend analysis of average and sectorial RNFL thicknesses, and event analysis of the RNFL thickness maps and the RNFL thickness profiles can be used to detect and follow diffuse and focal RNFL progression. RNFL measurement with spectral-domain OCT could provide important information for use in formulating treatment plans and evaluating disease prognosis in the management of glaucoma.


2009 ◽  
Vol 17 (5) ◽  
pp. 3997 ◽  
Author(s):  
Donald C. Hood ◽  
Ali S. Raza ◽  
Kristine Y. Kay ◽  
Shlomit F. Sandler ◽  
Daiyan Xin ◽  
...  

Ophthalmology ◽  
1996 ◽  
Vol 103 (11) ◽  
pp. 1889-1898 ◽  
Author(s):  
Joel S. Schuman ◽  
Tamar Pedut-Kloizman ◽  
Ellen Hertzmark ◽  
Michael R. Hee ◽  
Jason R. Wilkins ◽  
...  

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