Changes of Peripapillary Nerve Fiber Layer and Foveal Thickness Measurements by Optical Coherence Tomography after Phacoemulsification in Non-Diabetic Non-Glaucomatous Patients with Senile Grade 1+ Cataract = تقييم تغير قياسات سمك طبقة الألياف العصبية المحيطة بقرص العصب البصري وسمك مركز الماقولة بعد إزالة المياة البيضاء باستخدام الماسح البصري المقطعي التوافقي في الأشخاص غير المصابين بمرض السكر أو الجلوكوما

2017 ◽  
Vol 46 (4) ◽  
pp. 939-952
Author(s):  
Mostafa F. Mohammed
Keyword(s):  
Optical Coherence Tomography ◽  
Nerve Fiber ◽  
Optical Coherence ◽  
Fiber Layer ◽  
Foveal Thickness ◽  
Nerve Fiber Layer ◽  
Thickness Measurements

scholarly journals Reproducibility of Nerve Fiber Layer Thickness Measurements Using Optical Coherence Tomography

Ophthalmology ◽  
1996 ◽  
Vol 103 (11) ◽  
pp. 1889-1898 ◽  
Author(s):  
Joel S. Schuman ◽  
Tamar Pedut-Kloizman ◽  
Ellen Hertzmark ◽  
Michael R. Hee ◽  
Jason R. Wilkins ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Nerve Fiber ◽  
Layer Thickness ◽  
Optical Coherence ◽  
Fiber Layer ◽  
Nerve Fiber Layer ◽  
Nerve Fiber Layer Thickness ◽  
Thickness Measurements

scholarly journals Visible light optical coherence tomography of peripapillary retinal nerve fiber layer reflectivity in glaucoma

2021 ◽  
Author(s):  
Weiye Song ◽  
Sui Zhang ◽  
Yumi Mun Kim ◽  
Natalie Saldlak ◽  
Marissa G. Fiorello ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Visible Light ◽  
Linear Model ◽  
Nerve Fiber ◽  
Retinal Nerve Fiber Layer ◽  
Mixed Linear Model ◽  
Optical Coherence ◽  
Fiber Layer ◽  
Nerve Fiber Layer ◽  
Thickness Measurements

PurposeTo evaluate the clinical utility of visible light optical coherence tomography (VIS-OCT) and to test whether VIS-OCT reflectivity and spectroscopy of peripapillary retinal nerve fiber layer (pRNFL) are correlated with severity of glaucoma, compared with standard-of-care OCT thickness measurements.DesignCross-sectional study.MethodFifty-four eyes from three groups of subjects (normal, glaucoma suspect, and glaucoma) were scanned by a custom-designed dual-channel device that simultaneously acquired visible (VIS-OCT) and near-infrared OCT (NIR-OCT) images. A 5×5 mm2 scan was taken of the peripapillary nerve fiber layer (pRNFL).The pRNFL reflectivity was calculated for both channels and the spectroscopic marker was quantified by pVN, defined by the ratio of VIS-OCT to NIR-OCT pRNFL reflectivity. The results were compared with ophthalmic exams and clinical Zeiss OCT measurements. Mixed linear model was used to evaluate the association of imaging markers with glaucoma severity.ResultsVIS-OCT pRNFL reflectivity significantly, se uentially declined from normal to suspect to glaucoma (3.42 ± 0.35, 2.58 ± 0.37, 2.16 ± 0.39, mean ± SD), as did NIR-OCT pRNFL reflectivity (2.46 ± 0.24, 2.27 ± 0.24, 1.96 ± 0.25). The pVN also had the same decreasing trend among three groups (1.39 ± 0.08, 1.14 ± 0.08, 1.08 ± 0.10). Normal and suspect eyes were significantly different in VIS-OCT pRNFL reflectivity (p=0.002), pVN (p<0.001) but not in NIR-OCT pRNFL reflectivity (p=0.14), circumpapillary RNFL (cpRNFL) thickness (p=0.17), or macular ganglion cell layer and inner plexiform layer (GCL+IPL) thickness (p=0.07) in the mixed linear model.ConclusionVIS-OCT pRNFL reflectivity and pVN was more sensitive in separating suspect eyes from normal ones than clinical OCT thickness measurements. VIS-OCT pRNFL reflectivity and pVN could be a useful metric in early detection of glaucoma upon further longitudinal validation.

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