scholarly journals Animal Experiments in Biomedical Research: A Historical Perspective

Animals ◽  
2013 ◽  
Vol 3 (1) ◽  
pp. 238-273 ◽  
Author(s):  
Nuno Franco
Keyword(s):  
Biomedical Research ◽  
Historical Perspective ◽  
Animal Experiments

Epistemology and the Ethics of Animal Experimentation

2021 ◽  
pp. 67-96
Author(s):  
Mylan Engel Jr.
Keyword(s):  
Animal Models ◽  
Biomedical Research ◽  
Human Disease ◽  
Animal Experiments ◽  
Animal Experimentation ◽  
Proper Treatment ◽  
Continued Use

In this chapter, Mylan Engel Jr. argues that animal experimentation is neither epistemically nor morally justified and should be abolished. Engel argues that the only serious attempt at justifying animal experimentation is the benefits argument, according to which animal experiments are justified because the benefits that humans receive from the experiments outweigh the costs imposed on the animal subjects. According to Engel, the benefits we allegedly receive from animal-based biomedical research are primarily epistemic, in that experimenting on animal models is supposed to provide us with knowledge of the origin and proper treatment of human disease. However, Engel argues that animal models are extremely unreliable at predicting how drugs will behave in humans, whether candidate drugs will be safe in humans, and whether candidate drugs will be effective in humans. Engel concludes that animal-based research fails to provide the epistemic, and thereby moral, benefits needed to justify its continued use.

Ethics of Death and Dying: Historical Perspective

1979 ◽  
Vol 9 (3) ◽  
pp. 203-237 ◽  
Author(s):  
Gerald J. Gruman
Keyword(s):  
Intellectual History ◽  
Biomedical Research ◽  
Medical Practice ◽  
Historical Perspective ◽  
Ethical Dilemmas ◽  
Death And Dying ◽  
Therapeutic Principle ◽  
The Individual

The ethical dilemmas surrounding dying and death today can be understood more adequately when placed in an historical perspective. The methodology of intellectual history is employed to examine the sequence of cultural stages from prehistory to the contemporary scene, using the concept of the death system (Kastenbaum) as an organizing formulation. It is suggested in conclusion that a modern version of the meliorist ethos can lend support to the on-going modes of biomedical research and the application of the activist therapeutic principle in medical practice. Humanity has labored and suffered too much to abandon hope at this time and either submerge the personality of the individual or turn to a nihilistic “death worship” (Borkenau).

scholarly journals Archiving of zebrafish lines can reduce animal experiments in biomedical research

EMBO Reports ◽  
2016 ◽  
Vol 18 (1) ◽  
pp. 1-2 ◽  
Author(s):  
Robert Geisler ◽  
Almut Köhler ◽  
Thomas Dickmeis ◽  
Uwe Strähle
Keyword(s):  
Biomedical Research ◽  
Animal Experiments

scholarly journals A historical perspective and prospects of biomedical research on parasitic diseases

2001 ◽  
Vol 43 (4) ◽  
pp. 209-212 ◽  
Author(s):  
Augusto SIMÕES-BARBOSA ◽  
Constança SIMÕES BARBOSA ◽  
Frederico SIMÕES BARBOSA
Keyword(s):  
Sustainable Development ◽  
Biomedical Research ◽  
Historical Perspective ◽  
Scientific Progress ◽  
Health Science ◽  
Parasitic Diseases ◽  
Modern Life ◽  
Black And White ◽  
Health Quality ◽  
Conservation Of Biodiversity

We all hope that biotechnology will answer some social and economical unavoidable requirements of the modern life. It is necessary to improve agriculture production, food abundance and health quality in a sustainable development. It is indeed a hard task to keep the progress on taking into account the rational use of genetic resources and the conservation of biodiversity. In this context, a historical perspective and prospects of the biomedical research on parasitic diseases is described in a view of three generations of investigators. This work begins with a picture of the scientific progress on biomedical research and human health over the last centuries. This black-and-white picture is painted by dissecting current advancements of molecular biology and modern genetics, which are outlined at the meaning of prospecting achievements in health science for this new millenium.

scholarly journals Issues of Animal Welfare Regulations on Pharmacy Education and Research in India

2021 ◽  
pp. 185-194
Author(s):  
Anuradha Girme ◽  
Anil Pawar
Keyword(s):  
Biomedical Research ◽  
Animal Experiments ◽  
Well Being ◽  
Animal Experimentation ◽  
Pharmacy Education ◽  
Continuous Increase ◽  
Alternative Technologies ◽  
Research Activities ◽  
Animal Use ◽  
The Impact

Biomedical research is essential to the health and well-being of our society. Animal use for biomedical research has a long history and is routinely performed in new drug discovery and development processes. Animal experiments are an integral part of the curriculum for students in the life sciences, including pharmacy, to learn how to conduct animal experiments. These experiments may cause pain and distress to the animals. Laws and regulations have been enacted to make it illegal to cause undue pain or suffering to animals. These guidelines provide that due and full consideration should be given to alternative technologies not involving animal testing. Despite the movement to minimize animal use in research, pieces of evidence show that there has been a continuous increase in the worldwide use of laboratory animals over 10 years, from 115.2 animals to 192.1 million. The lack of suitable animal-alternative technologies and unavailability of required infrastructures are some of the reasons for animal use. As per directives of the University Grant Commission, the Pharmacy Council of India has decided to prohibit animal experimentation in pharmacy education. This adversely affected teaching and research activities in pharmacy institutions. As a result, the number of seats available for the postgraduate course (Master of Pharmacy) in Pharmacology is decreasing every year. In 2021, the highest number of seats are available for Pharmaceutics (9510, 35%) followed by that for the Pharmacology (4620, 17%). This article mainly focuses on the background of Indian legislation for animal experimentation and the impact of these regulations on animal experiments for pharmacy education and research in India.

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