scholarly journals Effect of Dietary Flaxseed Oil Supplementation on the Redox Status, Haematological and Biochemical Parameters of Horses’ Blood

Animals ◽  
2020 ◽  
Vol 10 (12) ◽  
pp. 2244
Author(s):  
Iwona Sembratowicz ◽  
Grzegorz Zięba ◽  
Ewelina Cholewinska ◽  
Anna Czech
Keyword(s):  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Redox Status ◽  
Flaxseed Oil ◽  
Haematological Parameters ◽  
Lower Plasma ◽  
Antioxidant Defence ◽  
Lactate Dehydrogenase Activity ◽  
Malonyl Dialdehyde ◽  
Biochemical Indices

This study compared the effect of two dietary vegetable oils on plasma biochemical indices, haematological parameters, and redox status of horses. Forty riding horses (20 mares and 20 stallions) of the Malopolski breed were divided equally into two groups that were similar in terms of age, sex, and body weight (on average 530 ± 30 kg). The horses received soybean oil (SO) or flaxseed oil (FO) in the amount of 25 mL per 100 kg BW/day. After 60 days, blood was collected for biochemical and haematological analyses. The results show that horses receiving FO as compared to the SO group had significantly lower plasma levels of glucose, low density lipoprotein cholesterol, total cholesterol/high-density lipoprotein (HDL) ratio and triacylglycerols, as well as the activities of alanine aminotransferase and alkaline phosphatase. In turn, %HDL-TC and lactate dehydrogenase activity were significantly higher in the FO group. The inclusion of FO in the diet contributed to an increase in antioxidant indices: creatinine, vitamin C, copper, and zinc contents and also superoxide dismutase and catalase activities. The level of the end product of lipid peroxidation, i.e., malonyl dialdehyde, in the FO group as compared to the SO group was significantly lower. Moreover, FO caused an elevation in red blood cell indicators, lymphocyte count and lysozymes. In conclusion, FO exerts a beneficial effect by stimulating antioxidant defence mechanisms of horses and reducing the severity of oxidative stress. FO also improved the lipid profile and haematological parameters of the blood. The replacement of SO by FO is recommended based on these findings.

scholarly journals Effects of Corn Supplementation into PKC-Urea Treated Rice Straw Basal Diet on Hematological, Biochemical Indices and Serum Mineral Level in Lambs

Animals ◽  
2019 ◽  
Vol 9 (10) ◽  
pp. 781
Author(s):  
Osama Anwer Saeed ◽  
Awis Qurni Sazili ◽  
Henny Akit ◽  
Abdul Razak Alimon ◽  
Anjas Asmara Samsudin
Keyword(s):  
Rice Straw ◽  
Hematological Parameters ◽  
Control Diet ◽  
Low Density Lipoprotein ◽  
Palm Kernel ◽  
Density Lipoprotein ◽  
Basal Diet ◽  
Hematological And Biochemical Parameters ◽  
Experimental Treatments ◽  
Biochemical Indices

Twenty-seven Dorper lambs were used to determine the effect of supplementing corn as a source of energy into the palm kernel cake (PKC) urea-treated rice straw basal diet on the blood metabolic profile and metals in lambs. The lambs were randomly allotted to three experimental treatments according to their initial body weight for a 120 day trial. Dietary treatments were: T1 (control diet) = 75.3% of PKC + 0% corn, T2 = 70.3% of PKC + 5% corn, and T3 = 65.3% of PKC + 10% corn. The results of this study indicated that copper (Cu), selenium (Se), zinc (Zn), and iron (Fe) concentration intake, retention, and its absorption from the gut and apparent mineral digestibility were highly significant for the levels of corn supplementation. The biochemical and hematological parameters remained within normal levels with the treatments, but the white blood cell, eosinophil count, cholesterol, and low-density lipoprotein cholesterol (LDL) were significantly higher in T3. Treatment 3 significantly increased the concentration of Se and Fe, while Zn was reduced in the blood serum of lambs on day 120. The result shows that the inclusion of corn has no effect on the hematological and biochemical parameters of lambs after incorporating corn into the PKC-based diet at 5% and 10%.

scholarly journals Effects of Organized Physical Activity on Selected Health Indices among Women Older than 55 Years

2015 ◽  
Vol 2015 ◽  
pp. 1-8 ◽  
Author(s):  
Piotr Zmijewski ◽  
Krzysztof Mazurek ◽  
Ewa Kozdron ◽  
Piotr Szczypiorski ◽  
Agata Frysztak
Keyword(s):  
Physical Activity ◽  
Exercise Capacity ◽  
Positive Impact ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Cvd Risk ◽  
Health Indices ◽  
Risk Of Death ◽  
Before And After ◽  
Biochemical Indices

The main aim of this study was to determine health benefits among women older than 55 years who participated in organized, group-based physical activity (OPA). Thirty-five women aged 65.0 ± 7.3 years volunteered for this study. The classical and nonclassical cardiovascular (CVD) risk factors were measured before and after a 2-week OPA camp in a remote location and 3 months of OPA. Self-guided physical activity was analyzed 18 months after OPA. Two-week effects included significant decreases in body mass index, waist and hip circumferences, resting systolic and diastolic blood pressure (BP) and resting heart rate, improved exercise capacity (EC), improved low-density lipoprotein and high-density lipoprotein (HDL-C), cholesterol, and other atherogenic lipid indices (ALI), and a reduction in 10-year estimated risk of death from CVD. Three-month effects included a further decrease in systolic BP, improvements in EC and HDL-C, and maintenance of lower levels of ALI, as well as lower CVD risk. The implementation of the OPA programme had a positive impact on somatic features, exercise capacity, biochemical indices, and risk for death from CVD. The presented programme can be regarded as an effective element of primary prevention of cardiovascular diseases among women older than 55 years.

scholarly journals Effects of Propofol, a Sedative-Hypnotic Drug, on the Lipid Profile, Antioxidant Indices, and Cardiovascular Marker Enzymes in Wistar Rats

2013 ◽  
Vol 2013 ◽  
pp. 1-6 ◽  
Author(s):  
Oluwatosin A. Adaramoye ◽  
Olugbenga Akinwonmi ◽  
Olubukola Akanni
Keyword(s):  
Lipid Profile ◽  
Corn Oil ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Lipoprotein Cholesterol ◽  
Biological Processes ◽  
Low Density Lipoprotein Cholesterol ◽  
Biochemical Indices ◽  
Dose Dependent Increase ◽  
Dose Dependent

In recent years, the activity of anaesthetic propofol on biological processes has been attracting attention. The effect of propofol on biochemical indices in animals is unknown. In this study, we examined the effects of propofol on lipid profile, antioxidant indices, and cardiovascular marker (CVM) enzymes in rats. The study consists of three groups of seven rats each. Group one received corn oil (Control) while groups two and three received propofol (doses of 2 and 4 mg/kg body weight, resp.). Results showed that administration of propofol caused a significant (P<0.05) and dose-dependent increase in the levels of total bilirubin. Propofol at 2 and 4 mg/kg increased the levels of serum total cholesterol by 74% and 55%, triglycerides by 97% and 115%, and LDL-C (low-density lipoprotein-cholesterol) by 45% and 73%, respectively, while HDL-C (high-density lipoprotein-cholesterol) decreased by 41% and 54%, respectively. Propofol significantly (P<0.05) increased the levels of the hepatic reduced glutathione (GSH) and activities of GSH-dependent enzymes. Propofol at 2 and 4 mg/kg increased the activities of CVM enzymes: lactate dehydrogenase by 1.7 and 1.8 folds and creatinine phosphokinase by 2.0 and 2.1 folds, respectively. Taken together, propofol increased the levels of GSH and GSH-dependent enzymes but adversely affected the lipid profile of the rats.

scholarly journals Serum biochemical and haematological reference intervals for water buffalo (Bubalus bubalis) heifers

2014 ◽  
Vol 85 (1) ◽  
Author(s):  
Mahmoud R. Abd Ellah ◽  
Maha I. Hamed ◽  
Derar R. Ibrahim ◽  
Hassan Z. Rateb
Keyword(s):  
Biochemical Analysis ◽  
Water Buffalo ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Bubalus Bubalis ◽  
Reference Intervals ◽  
Low Density ◽  
Lactate Dehydrogenase Activity ◽  
Serum Biochemical ◽  
Glutamyl Transferase

Based on a review of the literature, reference intervals for water buffalo (Bubalus bubalis) serum biochemistry and haematology have not previously been published. The current study was done to establish reference intervals for water buffalo heifers. The International Federation of Clinical Chemistry stated that at least 120 values are necessary to obtain reliable estimates for reference intervals. A total number of 127 clinically healthy buffalo heifers (1–2 years old) were included in the study. Animals were examined at buffalo farms that belong to Assiut Governorate, Egypt. Three types of samples were collected: serum samples for biochemical analysis, whole blood samples for haematological analysis and faecal samples for parasitological examination. Animals that fitted the inclusion criteria were included in the study. Biochemical analysis included serum total proteins, albumin, total globulins, alpha, beta and gamma globulin levels, and aspartate aminotransferase, alanine aminotransferase, gamma glutamyl transferase, creatine phosphokinase and lactate dehydrogenase activity. In addition to the above, serum creatinine, urea, total bilirubin, direct bilirubin, indirect bilirubin, sodium, potassium, chloride, magnesium, calcium, phosphorus, copper, zinc, iron, triglycerides, high density lipoprotein, low density lipoprotein, very low density lipoprotein, glucose levels and 20 haematological variables were measured. The 95.0% reference intervals were calculated by removing the upper and lower 2.5% of the interval for each serum biochemical constituent to give the 2.5 and 97.5 percentiles. Confidence intervals were calculated for each reference limit. Reference intervals from the current study were compared with established values for cows. The current study is as far as could be determined the first that establishes reference intervals for the serum biochemical and haematological parameters in water buffalo heifers.

Hyperinsulinemia and in vivo very-low-density lipoprotein-triglyceride kinetics

1984 ◽  
Vol 246 (2) ◽  
pp. E187-E192 ◽  
Author(s):  
G. Steiner ◽  
F. J. Haynes ◽  
G. Yoshino ◽  
M. Vranic
Keyword(s):  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Plasma Free Fatty Acid ◽  
Control Group ◽  
Very Low Density Lipoprotein ◽  
Low Density ◽  
Lower Plasma ◽  
Glucose Levels ◽  
Ad Libitum

The effect of hyperinsulinemia (2 wk of twice daily NPH insulin) on the kinetics of very-low-density lipoprotein (VLDL)-triglyceride (TG) was studied in rats. To avoid profound hypoglycemia the rats were allowed sucrose ad libitum. Two control groups were needed: chow only and ad libitum sucrose-supplemented (high-CHO). The insulin-treated rats had 15 times higher IRI and 50% lower plasma glucose levels than either control group. Their TG production exceeded and their TG concentrations were less than those of either control group. This indicated that their TG removal was increased even more than their TG production. This increase in TG production occurred despite lower plasma free fatty acid (FFA) levels, suggesting that a greater proportion of TG fatty acids came from a source other than FFA. Compared with chow controls, high-CHO controls had the same peripheral IRI, a slight increase in TG production, and an increase in TG concentration. The differences between the effects of CHO supplementation alone or together with injected insulin may relate to the IRI and/or the route of access of insulin (peripheral vs. portal). The present studies indicate that hyperinsulinemia, either directly or indirectly, accelerates triglyceride turnover.

Comparison of Clinical and Laboratory Characteristics of General Paresis and Non-Neurosyphilis Dementia

2018 ◽  
Vol 80 (1-2) ◽  
pp. 82-86 ◽  
Author(s):  
Man-Li Tong ◽  
Yu-Yan Chen ◽  
Xiao-Zhen Zhu ◽  
Kun Gao ◽  
Hui-Lin Zhang ◽  
...  
Keyword(s):  
Behavioral Interventions ◽  
Low Density Lipoprotein ◽  
Treponema Pallidum ◽  
Density Lipoprotein ◽  
General Paresis ◽  
Positive Serology ◽  
Laboratory Findings ◽  
Protein Levels ◽  
Laboratory Features ◽  
Biochemical Indices

Background: The differential diagnosis of general paresis (GP) and non-neurosyphilis (NS) dementia is not clearly defined. The present study examined the differences in clinical and laboratory features of GP and non-NS dementia. Materials and Methods: We retrospectively examined clinical and laboratory features of 85 GP patients and 196 non-NS dementia patients. Data were collected from Zhongshan Hospital between June 2005 and June 2014. Results: The GP group had a higher percentage of males (83.53%, 71/85) and younger median age ([52 [interquartile range 47.0–61.0] vs. 76 [68.3–82.0] years) than the non-NS dementia group. GP have higher Mini-Mental State Examination (MMSE; Z = –5.809; p = 0.000) than non-NS dementia. Distribution of CDR scores were significantly higher in the non-NS group than GP group (χ2 = 29.153; p = 0.000). The laboratory findings showed significantly different total cholesterol (CH), low-density lipoprotein CH and homocysteine levels between the 2 groups. Serologic testing for syphilis revealed that the GP group had higher seropositive rapid plasma reagin (RPR) and Treponema pallidum particle agglutination (TPPA) rates than the non-NS dementia group (96.47% [82/85] vs. 0.51% [1/196], Z = –2.663, p = 0.008; 100% [85/85] vs. 1.02% [2/196], Z = –2.663, p = 0.008). Interestingly, cerebrospinal fluid (CSF) biochemical indices, including pleocytosis rates, increased protein levels, and positive RPR and TPPA rates in the GP group were higher than that in the non-NS dementia group. Conclusions: Based on these preliminary data, patients with clinically evident symptoms of dementia, especially middle-aged males, should undergo blood tests for syphilis. All patients with positive serology results should undergo CSF examinations to diagnose GP dementia before further pharmaceutical and behavioral interventions.

Association of Dyslipidemia, Oxidative Stress, and Inflammation With Redox Status in VLDL, LDL, and HDL Lipoproteins in Patients With Renal Disease

Angiology ◽  
2018 ◽  
Vol 69 (10) ◽  
pp. 861-870 ◽  
Author(s):  
Milica Miljkovic ◽  
Aleksandra Stefanovic ◽  
Sanja Simic-Ogrizovic ◽  
Jelena Vekic ◽  
Natasa Bogavac-Stanojevic ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Renal Disease ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Redox Status ◽  
Cardiovascular Complications ◽  
Paraoxonase 1 ◽  
Pon1 Activity ◽  
Enzyme Linked Immunosorbent Assay ◽  
Low Density

Some cardiovascular complications in patients with chronic kidney disease and end-stage renal disease may be caused by structurally and functionally modified lipoproteins. Redox status (advanced oxidation protein products [AOPPs]), prooxidant–antioxidant balance, total protein sulfhydryl (SH-groups), and paraoxonase 1 (PON1) activity were assessed in 77 renal patients and 20 controls. Lipoproteins were isolated using ultracentrifugation. PON1, PON3, and pentraxin-3 concentration were determined by enzyme-linked immunosorbent assay (ELISA). Dyslipidemia-Oxy-Inflammation (DOI) score was calculated as a sum of dyslipidemia, oxidative stress, and inflammation scores. The dyslipidemia score ( P < .001), oxy score ( P < .01), inflammation score (P < .001), and the DOI score ( P < .001) were higher in patient groups compared with controls. The very-low-density lipoprotein (VLDL) fraction contained the highest amount of AOPP ( P < .001) compared with other lipoprotein fractions in all groups. The low-density lipoprotein (LDL) fraction contained elevated AOPP in all groups compared with the high-density lipoprotein (HDL) fraction ( P < .001). Significant positive correlation was observed between AOPP in LDL fraction and DOI score (ρ = 0.510, P < .01). Dyslipidemia, oxidative stress, and inflammation play an interactive role in renal disease and are mutually associated with redox status in VLDL, LDL, and HDL lipoproteins in plasma of renal patients.

scholarly journals Variations in haematological and serum indices of finishing broiler birds fed neem (Azadirachta indica) and garlic (Allium sativum) as phytobiotics

2021 ◽  
Vol 42 (2) ◽  
pp. 129-140
Author(s):  
S. B. Mohammad ◽  
R. A. Sobayo ◽  
O. M. Sogunle ◽  
A. O. Oso ◽  
O. A. Adeyemi
Keyword(s):  
Total Protein ◽  
Broiler Chickens ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Haematological Parameters ◽  
Treatment Groups ◽  
Randomized Design ◽  
Four Levels ◽  
Feeding Diets ◽  
Different Levels

One hundred and eighty day-old Cobb broiler chickens were used to evaluate the effects of feeding diets containing neem leaf meal (NLM), garlic meal (GM) and their combination (NLM + GM) on haematological and serum indices of finishing broiler. The birds were divided into twelve treatment groups of fifteen chicks with three replicate of five chicks each. The diets contained NLM, GM and NLM + GM at four levels of inclusion; Omg/kg, 500mg/kg, 1000mg/kg and 1500mg/kg. The experiment was arranged in a 3 x 4 factorial layout in a completely randomized design (CRD). The inclusion of NLM, GM and NLM + GM did not significantly (P>0.05) influence haematological parameters. Different levels of inclusion significantly (P<0.05) influenced absolute haematological parameters. (P<0.05) interaction of additives and levels of inclusion were observed in most of the haematological indices studied. NLM+GM at 500mg/kg showed the highest PCV value. Highest Hb and RBC values were observed in birds fed GM at 1500mg/kg. Different levels of inclusion significantly (P<0.05) influenced total protein and albumin levels. Lowest (P<0.05) amounts of total protein (8.88mg/dl) and albumin (2.20mg/dl) were recorded in birds fed 1500mg/kg inclusion levels compared to those birds on Omg/kg inclusion level..Additives and levels of inclusion (P<0.05) affected cholesterol value of finishing broiler birds. There was a reduction in cholesterol (93.38mg/dl) and HDL (52.57mg/dl) values of birds fed GM than these fed NLM + GM. Significant (P<0.05) interactions were observed in alanine aminotransferase (ALI), urea, cholesterol and low density lipoprotein (LDL) values. It was evident that feeding of the additives at different levels affected the blood picture of the finishing broiler chickens.

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