scholarly journals Effects of Corn Supplementation into PKC-Urea Treated Rice Straw Basal Diet on Hematological, Biochemical Indices and Serum Mineral Level in Lambs

Animals ◽  
2019 ◽  
Vol 9 (10) ◽  
pp. 781
Author(s):  
Osama Anwer Saeed ◽  
Awis Qurni Sazili ◽  
Henny Akit ◽  
Abdul Razak Alimon ◽  
Anjas Asmara Samsudin
Keyword(s):  
Rice Straw ◽  
Hematological Parameters ◽  
Control Diet ◽  
Low Density Lipoprotein ◽  
Palm Kernel ◽  
Density Lipoprotein ◽  
Basal Diet ◽  
Hematological And Biochemical Parameters ◽  
Experimental Treatments ◽  
Biochemical Indices

Twenty-seven Dorper lambs were used to determine the effect of supplementing corn as a source of energy into the palm kernel cake (PKC) urea-treated rice straw basal diet on the blood metabolic profile and metals in lambs. The lambs were randomly allotted to three experimental treatments according to their initial body weight for a 120 day trial. Dietary treatments were: T1 (control diet) = 75.3% of PKC + 0% corn, T2 = 70.3% of PKC + 5% corn, and T3 = 65.3% of PKC + 10% corn. The results of this study indicated that copper (Cu), selenium (Se), zinc (Zn), and iron (Fe) concentration intake, retention, and its absorption from the gut and apparent mineral digestibility were highly significant for the levels of corn supplementation. The biochemical and hematological parameters remained within normal levels with the treatments, but the white blood cell, eosinophil count, cholesterol, and low-density lipoprotein cholesterol (LDL) were significantly higher in T3. Treatment 3 significantly increased the concentration of Se and Fe, while Zn was reduced in the blood serum of lambs on day 120. The result shows that the inclusion of corn has no effect on the hematological and biochemical parameters of lambs after incorporating corn into the PKC-based diet at 5% and 10%.

scholarly journals Haematological and serum biochemical indices of growing pigs fed varying levels of beniseed (Sesamum indicum L.) hull in replacement for maize.

2021 ◽  
Vol 21 (9) ◽  
pp. 18629-18643
Author(s):  
Rotimi Olajide ◽  
◽  
EK Asaniyan ◽  
BO Olusegun ◽  
SM Aro ◽  
...  
Keyword(s):  
Control Diet ◽  
Density Lipoprotein ◽  
Basal Diet ◽  
Nutrient Content ◽  
Growing Pigs ◽  
Large White ◽  
Serum Biochemical ◽  
Wbc Count ◽  
Biochemical Indices ◽  
Dietary Treatments

A feeding trial was conducted to evaluate the nutrient content of beniseed hull (BSH) as a substitute for maize, and its effect on haematological and serum biochemical indices of growing pigs. Sixty 8-weeks old growing pigs (Landrace x Large white) were randomly allotted into five dietary treatments with three replicates of four animals per replicate in a completely randomized design. Five diets were formulated by incorporating BSH into the basal diet to replace maize at 0, 25, 50, 75 and 100% designated as D1 (control), D2, D3, D4 and D5, respectively and fed to growing pigs for ten weeks. Diets had no significant effect on the parameters measured, except White blood cell (WBC) and Lymphocytes. The highest WBC count (x109/L) (P < 0.05) of 23.70 was obtained in pigs fed 50% BSH-based diets compared with 15.55 (0% BSH), 14.00 (25% BSH), 21.45 (75% BSH) and 15.10 (100% BSH), respectively. The lymphocyte counts of pigs fed 25% BSH (60.00%) and 75% BSH (76.50%) were statistically similar to those on other dietary treatments. The cholesterol values recorded in pigs fed with the control diet (0% BSH) (125.00 mg/dL) and 25% BSH (122.50 mg/dL) were similar but significantly (P < 0.05) reduced to 119.50 mg/dL (50% BSH), 118.00 mg/dL(75% BSH) and 104.00 mg/dL (100% BSH), respectively, as the level of BSH increases. The High-density lipoprotein, HDL value (20.95 mg/dL) of pigs fed with control diet (0% BSH) was significantly (P < 0.05) lower than HDL values of pigs placed on other diets. The total protein (g/dL) 7.08 (0% BSH), 7.11 (25% BSH), 7.00 (50% BSH) were similar (P > 0.05) but significantly (P < 0.05) higher than 6.81 (75% BSH) and 6.66 (100% BSH). Beniseed hull poses no health challenge to the growing pigs as depicted by normal haematological and serum biochemical indices including lowest cholesterol at 100% BSH; beniseed hull could safely replace maize in pig’s diets up to 100% level.

Effect of dietary probiotic, antibiotic or combination on broiler performance, cecum microbial population and ileal development

2020 ◽  
Vol 21 (3) ◽  
pp. 74-79
Author(s):  
Ahmed Elbaz ◽  
Said El-sheikh
Keyword(s):  
Control Diet ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Experimental Period ◽  
Nutrient Digestibility ◽  
Lipoprotein Cholesterol ◽  
Control Group ◽  
Gut Health ◽  
Feed Conversion ◽  
Broiler Performance

Objective: To investigate the effect of antibiotics and/or probiotics on broiler performance, some serum metabolites, cecum microflora composition, and ileum histomorphology under the Egyptian conditions. Design: Randomized controlled experimental study. Animals: Two hundred forty 1-day-old Ross (308) chicks were reared till 35 days of age. Procedures: The birds were randomly allocated into four main groups: a control diet without additives (CON); probiotic (Lactobacillus acidophilus) supplemented diet (PRO); antibiotic (Avilamycin) supplemented diet (ANT) and a mix group (AP) that received antibiotic in the diet form 1 to 4 days of age and treated during the rest of the experimental period with probiotics. Results: Chickens fed on probiotic or antibiotic diets had linear improvement in live body weight (LBW) and feed conversion ratio (FCR) compared with the control group, while the best LBW and FCR were in the AP group. An improvement in the nutrient digestibility was observed in the probiotic added groups (PRO and AP). Serum cholesterol and low-density lipoprotein cholesterol contents decreased when antimicrobial (probiotic or antibiotic) supplementations were used, while there was an increase in high-density lipoprotein cholesterol contents, serum total protein, and albumin levels. Among all groups, cecum Clostridium perfringens and Escherichia coli counts decreased; however, there was an increase in Lactobacillus count compared to the control group. In probiotic supplemented groups (PRO and AP), a significant (P<0.05) improvement in ilea architecture. Conclusion and clinical relevance: Using probiotic after initial treatment with an antibiotic in broiler diets had a positive effect on broiler growth performance, gut health (improved cecum microbial populations and ileum histomorphology), and nutrient digestibility.

Clofibrate causes an upregulation of PPAR-α target genes but does not alter expression of SREBP target genes in liver and adipose tissue of pigs

2007 ◽  
Vol 293 (1) ◽  
pp. R70-R77 ◽  
Author(s):  
Sebastian Luci ◽  
Beatrice Giemsa ◽  
Holger Kluge ◽  
Klaus Eder
Keyword(s):  
Adipose Tissue ◽  
Target Genes ◽  
Regulatory Element ◽  
Control Diet ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Cholesterol Homeostasis ◽  
Peroxisome Proliferator ◽  
Peroxisome Proliferator Activated Receptor ◽  
Hepatic Expression

This study investigated the effect of clofibrate treatment on expression of target genes of peroxisome proliferator-activated receptor (PPAR)-α and various genes of the lipid metabolism in liver and adipose tissue of pigs. An experiment with 18 pigs was performed in which pigs were fed either a control diet or the same diet supplemented with 5 g clofibrate/kg for 28 days. Pigs treated with clofibrate had heavier livers, moderately increased mRNA concentrations of various PPAR-α target genes in liver and adipose tissue, a higher concentration of 3-hydroxybutyrate, and markedly lower concentrations of triglycerides and cholesterol in plasma and lipoproteins than control pigs ( P < 0.05). mRNA concentrations of sterol regulatory element-binding proteins (SREBP)-1 and -2, insulin-induced genes ( Insig) -1 and Insig-2, and the SREBP target genes acetyl-CoA carboxylase, 3-methyl-3-hydroxyglutaryl-CoA reductase, and low-density lipoprotein receptor in liver and adipose tissue and mRNA concentrations of apolipoproteins A-I, A-II, and C-III in the liver were not different between both groups of pigs. In conclusion, this study shows that clofibrate treatment activates PPAR-α in liver and adipose tissue and has a strong hypotriglyceridemic and hypocholesterolemic effect in pigs. The finding that mRNA concentrations of some proteins responsible for the hypolipidemic action of fibrates in humans were not altered suggests that there were certain differences in the mode of action compared with humans. It is also shown that PPAR-α activation by clofibrate does not affect hepatic expression of SREBP target genes involved in synthesis of triglycerides and cholesterol homeostasis in liver and adipose tissue of pigs.

scholarly journals Evaluation of lipid profiles and hematological parameters in hypertensive patients: Laboratory-based cross-sectional study

2018 ◽  
Vol 6 ◽  
pp. 205031211875666 ◽  
Author(s):  
Alemu Gebrie ◽  
Natesan Gnanasekaran ◽  
Menakath Menon ◽  
Mekonnen Sisay ◽  
Abriham Zegeye
Keyword(s):  
Blood Pressure ◽  
Blood Cell ◽  
Total Cholesterol ◽  
Hematological Parameters ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Lipid Profiles ◽  
Low Density ◽  
Blood Cell Count ◽  
Hypertensive Patients

Introduction: Hypertension and dyslipidemia are the two coexisting and synergizing major risk factors for cardiovascular diseases. The cellular constituents of blood affect the volume and viscosity of blood, thus playing a key role in regulating blood pressure. Overweight and obesity are key determinants of adverse metabolic changes including an increase in blood pressure. The aim of this study was to evaluate lipid profiles and hematological parameters in hypertensive patients at Debre Markos Referral Hospital, Northwest Ethiopia. Methods: Laboratory-based cross-sectional study was conducted in 100 eligible hypertensive patients at the hospital. The required amount of blood was withdrawn from the patients by healthcare professionals for immediate automated laboratory analyses. Data were collected on socio-demographic factors, anthropometric measurements, blood pressure, lipid profiles, and hematological parameters. Result: The mean serum levels of triglyceride, total cholesterol, and low-density lipoprotein were significantly higher than their respective cut-off values in the hypertensive patients. Besides, 54%, 52%, 35%, and 11% of the hypertensive patients had abnormal low-density lipoprotein, total cholesterol, triglyceride, and high-density lipoprotein levels, respectively. Higher levels of low-density lipoprotein, hemoglobin, and red blood cell count were observed in the hypertensive patients whose blood pressure had been poorly controlled than the controlled ones ( p < 0.05). Waist circumference had a significant positive association with the serum levels of total cholesterol and white blood cell count ( p < 0.05). Conclusion: Hypertensive patients had a high prevalence of lipid profile abnormalities and poorly controlled blood pressure which synergize in accelerating other cardiovascular diseases. Some hematological parameters such as red blood cell count are also increased as do the severity of hypertension.

scholarly journals Effects of different emulsifiers on growth performance, nutrient digestibility, and digestive enzyme activity in weanling pigs1

2019 ◽  
Vol 97 (10) ◽  
pp. 4235-4241
Author(s):  
Guangdong Bai ◽  
Wei He ◽  
Zheng Yang ◽  
Huiyang Fu ◽  
Shengnan Qiu ◽  
...  
Keyword(s):  
Growth Performance ◽  
Mrna Expression ◽  
Digestive Enzyme ◽  
Low Density Lipoprotein ◽  
Plasma Lipid ◽  
Density Lipoprotein ◽  
Dietary Treatment ◽  
Basal Diet ◽  
Nutrient Digestibility ◽  
Treatment Groups

Abstract The objective of this study was to investigate the effects of diets supplemented with sodium stearoyl-2-lactylate (SSL), polyglycerol fatty acid ester (PGFE), and combined emulsifiers (0.02% SSL and 0.08% PGFE) on growth performance, nutrient digestibility, and plasma lipid profiles in weaned piglets and to further evaluate the possible effects of feeding exogenous emulsifiers on digestive enzyme activities and liver bile acid (BA) metabolism. Twenty-eight barrows (age at 35 d, Duroc × Landrace × Yorkshire) with an initial BW of 10.13 ± 0.16 kg were randomly assigned to 4 dietary treatment groups (7 pigs/treatment). Dietary treatment groups included the following: 1) basal diet (Control, CTR); 2) basal diet with 0.1% SSL (SSL); 3) basal diet with 0.1% PGFE (PGFE); and 4) basal diet with 0.08% PGFE+0.02% SSL (PG-SL). SSL diet increased ADG and ADFI of piglets during day 0 to 17 (P < 0.05) compared with the CTR treatment. Piglets fed emulsifier diets experienced a significant improvement in the digestibility of nutrients (DM, CP, ether extract, energy, calcium, and phosphorus) during the first 17 d (P < 0.05). The level of low-density lipoprotein cholesterol (LDL-C) was lower in the PGFE and PG-SL treatment groups than in the CTR treatment group (P < 0.05). Feeding emulsifier diets increased the lipase activity of the pancreas when compared with the CTR diet (P < 0.05). Moreover, the emulsifier diets significantly increased the mRNA expression of FXR (P < 0.05) and decreased the mRNA expression of CYP27A1 (P < 0.05) in the liver. In conclusion, the addition of emulsifiers improved nutrient digestibility and increased the mRNA expression of FXR BA receptors while inhibiting the mRNA expression of BA biosynthesis by CYP27A1 in weanling piglets.

scholarly journals Evaluation of blood chemical, lipids profile and immune response on broiler chicks fed with milk thistle (Silybum mari- anum L.) and thyme (Thymus vulgaris L.) seeds in south-eastern Iran

2014 ◽  
Vol 5 (1) ◽  
Author(s):  
Hossein Ansari Nik ◽  
Omid Fani Makki ◽  
Ahmad Ebrahimzadeh ◽  
Arash Omidi
Keyword(s):  
Immune Response ◽  
Total Protein ◽  
Control Diet ◽  
Density Lipoprotein ◽  
Basal Diet ◽  
Lipoprotein Cholesterol ◽  
Thymus Vulgaris ◽  
Milk Thistle ◽  
Broiler Chicks ◽  
Lipids Profile

This study was conducted to investigate the effects of supplementation of milk thistle seeds (MTS) and thyme seeds (TS) on blood chemical, lipid profile and immune response in broiler chicks. In this study, 160 one-day-old chicks (Ross 308) were allocated to four treatments with four replicates based on a completely randomized design in a 2×2 factorial arrangement. The treatment groups were (A) basal control diet, (B) basal diet with 0.2 g/kg of MTS, (C) basal diet with 0.2 g/kg of TS and (D) basal diet with 0.2 g/kg of MTS and 0.2 g/kg of TS. Birds fed the (D) supplemented treatment (MTS plus TS) had the greatest levels of total protein, 4.26±0.27 g/L; albumin, 2.21±0.02 g/L; globulin 2.28±0.23 g/L; and aspartate aminotransferase (AST) activity, 152.18±4.46 U/L than the control birds [group (A)] (P&lt;0.05). MTS alone or in combination with TS reduced the cholesterol in the serum of the broilers (P&lt;0.05), and this effect was more pronounced for the (C) treatment (TS alone) (P&lt;0.05). Treatment consumption with MTS plus TS [group (D)] significantly increased the concentration of high-density lipoprotein cholesterol (HDL-C), 90.32±2.28 mmol/L, but low-density lipoprotein cholesterol (LDL-C), 10.44±0.07 mmol/L, and triglyceride concentrations, 60.75±2.65 mmol/L, were decreased compared to control (P&lt;0.05). However, none of the immunity parameters and liver enzymes differed significantly in MTS or TS groups. The present research indicated that supplements of MTS and TS have a protective influence on the lipids profile, total protein, globulin, albumin and AST levels in broiler chicks.

scholarly journals Control of the lipid oxidation in Nile tilapia feed

2016 ◽  
Vol 46 (9) ◽  
pp. 1675-1677 ◽  
Author(s):  
Thiago Luís Magnani Grassi ◽  
Marcelo Tacconi de Siqueira Marcos ◽  
Elisa Helena Giglio Ponsano
Keyword(s):  
Lipid Oxidation ◽  
Nile Tilapia ◽  
Control Diet ◽  
Bacterial Biomass ◽  
Thiobarbituric Acid ◽  
Basal Diet ◽  
Positive Control ◽  
Negative Control ◽  
Rubrivivax Gelatinosus ◽  
Experimental Treatments

ABSTRACT: The purpose of this research was to investigate the progress of the rancidity in Nile tilapia diets containing bacterial biomass of Rubrivivax gelatinosus . Six experimental treatments comprised basal diet (negative control), diet with asthaxanthin (positive control) and 4 diets with different concentrations of the bacterial biomass. The thiobarbituric acid assay for rancidity analyses were accomplished after 6 and 12 months of diets storage. It was concluded that Rubrivivax gelatinosus biomass minimized the racidity in Nile tilapia diets in 32.52 to 44.72% at 6 months and in 37.85 to 52.37% at 12 months of storage.

scholarly journals Increasing Selenium and Vitamin E in Dairy Cow Milk Improves the Quality of the Milk as Food for Children

Nutrients ◽  
2019 ◽  
Vol 11 (6) ◽  
pp. 1218 ◽  
Author(s):  
Arlindo Saran Netto ◽  
Márcia Saladini Vieira Salles ◽  
Luiz Carlos Roma Júnior ◽  
Silvia Maria Franciscato Cozzolino ◽  
Maria Teresa Moi Gonçalves ◽  
...  
Keyword(s):  
Vitamin E ◽  
Sunflower Oil ◽  
Control Diet ◽  
Low Density Lipoprotein ◽  
Skim Milk ◽  
Density Lipoprotein ◽  
Milk Intake ◽  
Cow Milk ◽  
Blood Concentrations ◽  
Beneficial Effects

In this study, we investigated the beneficial effects of milk biofortified with antioxidants on the health of children. Two experiments were conducted: experiment one evaluated the milk of 24 Jersey dairy cows (450 ± 25 kg of body weight (BW); 60 ± 30 days in milk dry matter intake (DIM)) given different diet treatments (CON = control diet; COANT = diet with vitamin E and selenium as antioxidants; OIL = diet with sunflower oil; and OANT = diet with sunflower oil containing more vitamin E and selenium as antioxidants), and experiment two evaluated the effect of the milk produced in the first experiment on the health of children (CON = control diet; COANT = diet with vitamin E and selenium as antioxidants; OIL = diet with sunflower oil; OANT = diet with sunflower oil containing more vitamin E and selenium as antioxidants; and SM = skim milk). One hundred children (8 to 10 years old) were evaluated in the second experiment. Blood samples were collected at 0 days of milk intake and 28 and 84 days after the start of milk intake. The cows fed the COANT and OANT diets showed greater selenium and vitamin E concentrations in their milk (p = 0.001), and the children who consumed the milk from those cows had higher concentrations of selenium and vitamin E in their blood (p = 0.001). The platelet (p = 0.001) and lymphocyte (p = 0.001) concentrations were increased in the blood of the children that consumed milk from cows fed the OANT diet compared to those in the children that consumed SM (p = 0.001). The children who consumed milk from cows fed the OIL diet treatment had increased concentrations of low density lipoprotein (LDL) and total cholesterol in their blood at the end of the supplementation period compared to children who consumed SM. The results of this study demonstrate that the consumption of biofortified milk increases the blood concentrations of selenium and vitamin E in children, which may be beneficial to their health.

scholarly journals Replacement of dietary fat with palm oil: effect on human serum lipids, lipoproteins and apolipoproteins

1992 ◽  
Vol 68 (3) ◽  
pp. 677-692 ◽  
Author(s):  
Kalyana Sundram ◽  
Gerard Hornstra ◽  
Adriana C. v. Houwelingen ◽  
Arnold D. M. Kester
Keyword(s):  
Palm Oil ◽  
Serum Lipids ◽  
Control Diet ◽  
Low Density Lipoprotein ◽  
Saturated Fat ◽  
Density Lipoprotein ◽  
Low Density ◽  
Oil Consumption ◽  
Double Blind ◽  
Cholesterol Ratio

Thirty-eight male volunteers participated in a double-blind cross-over trial evaluating the effect of replacing the usual sources of saturated fat in the Dutch diet (animal fats and hydrogenated oils) by palm oil, which is virtually free of cholesterol andtrans-fatty acids, on serum lipids, lipoproteins and apolipoproteins. Maximum (about 70%) replacement had no significant effect on serum total cholesterol or most lipoprotein fractions, but resulted in an 11% increase in serum high-density-lipoprotein (HDL)2-cholesterol relative to the control (P2= 0.01). The palm-oil diet also caused an 8% decrease in low-density-lipoprotein (LDL):HDL2+HDL3-cholesterol ratio (P2= 0.02) as well as a 9% decrease in triacylglycerols in the low-density-lipoprotein fractions (P2= 0.01). Palm oil consumption resulted in a 4% increase in serum apolipoprotein AI (P2= 0.008) and a 4% decrease in apolipoprotein B (P2= 0.01) relative to the control diet; the B:AI apolipoprotein ratio was decreased by 8% (P2< 0.0001). These results were not significantly affected by the different lipoprotein E phenotypes of the volunteers. Although the observed differences were relatively modest, the present study, nonetheless, indicates that dietary palm oil, when replacing a major part of the normal fat content in a Dutch diet, may slightly reduce the lipoprotein- and apolipoprotein-associated cardiovascular risk profiles

Carotid narrowing degree and plasma thiol levels in carotid endarterectomy patients

2005 ◽  
Vol 43 (10) ◽  
Author(s):  
Ciriaco Carru ◽  
Angelo Zinellu ◽  
Salvatore Sotgia ◽  
Roberto Chessa ◽  
Franco Piredda ◽  
...  
Keyword(s):  
Carotid Endarterectomy ◽  
Molecular Mechanisms ◽  
Hematological Parameters ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Mean Values ◽  
Homocysteine Concentration ◽  
Normal Limits ◽  
Common Risk Factors ◽  
The Mean

AbstractThe aim of this work was to study the association between plasma thiol levels and percentage carotid narrowing in a group of 68 patients who underwent a carotid endarterectomy, pertained as a risk factor for vascular and cardiovascular disease. Total plasma thiols were measured by capillary electrophoresis laser-induced fluorescence. The mean values of the hematological parameters studied were within normal limits and 25% of the patients were hyperhomocysteinemic (homocysteine >15μmol/L). Pearson's correlation between carotid narrowing degree and the most common risk factors for atherosclerosis showed a positive relationship only between carotid narrowing degree and cysteine levels (r=0.252; p<0.05). Stepwise multiple linear regression with carotid narrowing degree as the dependent variable, and cysteine, homocysteine, age, triglyceride and low-density lipoprotein-cholesterol as independent variables confirmed that cysteine was significantly associated with these variables. By regrouping the population according to cysteine and homocysteine concentration percentiles, we found positive correlation between these parameters and median values of carotid narrowing degree. Our study provides experimental evidence to confirm that plasma homocysteine and cysteine are involved in carotid narrowing after carotid endarterectomy intervention, suggesting that cysteine may be involved in the deleterious molecular mechanisms active in carotid stenosis.

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