scholarly journals Comparative Effects of Using New Multi-Strain Synbiotics on Chicken Growth Performance, Hematology, Serum Biochemistry and Immunity

Animals ◽  
2020 ◽  
Vol 10 (9) ◽  
pp. 1555
Author(s):  
Artur Żbikowski ◽  
Karol Pawłowski ◽  
Katarzyna Śliżewska ◽  
Beata Dolka ◽  
Joanna Nerc ◽  
...  
Keyword(s):  
Body Weight ◽  
Growth Performance ◽  
Blood Cells ◽  
Biochemical Parameters ◽  
Hematological Parameters ◽  
White Blood Cells ◽  
Serum Biochemistry ◽  
Control Group ◽  
Normal Ranges ◽  
Rbc Count

In this study, the influence of new multi-strain synbiotics on chicken growth performance, hematology, serum biochemistry and immunity was explored. Each synbiotic preparation (A, B and C) comprised three, four or five strains of Lactobacillus sp., respectively, as well as S. cerevisiae and inulin. All strains used in the synbiotics originated from wild-type strains from animal farms in Poland. Six groups of chickens, ROSS 308 line, were fed with three different synbiotics at a dose of 0.5 g/1 kg of feed. Body weight, as well as the biochemical and hematological parameters of the animals in each study group, were determined on the 7th, 14th, 28th and 42nd day of life. Body weight on day 42 differed between groups and was the highest in control group. This group also had the highestfeed conversion ratio (FCR) value. All measured biochemical parameters were in the normal ranges for poultry; however, we observed a lower alkaline phosphatase (AP) concentration on day 7 in the groups fed with synbiotics, which correlated with a lower level of triglycerides in those groups. The aspartate transaminase (AST) concentration was significantly lower in all groups on day 42 in comparison with the control. On day 7, the control group showed the highest concentration of Ca, K and P. Other parameters did not differ significantly throughout the experiment. All groups showed a similar tendency of increase in the red blood cells (RBC) count according to the age of the birds. Every white blood cells (WBC) population showed differences in the proportions between T and B lymphocytes. The T cell and monocyte counts increased until day 28 in all groups. The results showed that our newly developed synbiotic formulas do not have any unfavorable influence on chicken health and may modulate immune response and biochemical parameters. However, this hypothesis needs to be evaluated in future experiments.

scholarly journals Sex-Related Differences in Hematological Parameters and Organosomatic Indices of Oreochromis niloticus Exposed to Aflatoxin B1 Diet

Scientifica ◽  
2017 ◽  
Vol 2017 ◽  
pp. 1-7 ◽  
Author(s):  
Esther Marijani ◽  
Johnson Nasimolo ◽  
Emmanuel Kigadye ◽  
Gbemenou Joselin Benoit Gnonlonfin ◽  
Sheila Okoth
Keyword(s):  
Body Weight ◽  
Oreochromis Niloticus ◽  
Blood Cells ◽  
Hematological Parameters ◽  
White Blood Cells ◽  
Control Group ◽  
Feeding Experiment ◽  
Initial Body Weight ◽  
Male And Female ◽  
Males And Females

A 24-week feeding experiment was conducted to assess whether males and females of Oreochromis niloticus exhibit differences in their hematological responses and organosomatic indices to dietary AFB1 contamination. Triplicate groups of O. niloticus (initial body weight: 24.1 ± 0.6 g) were fed with four diets (Diets 1 to 4) containing 0, 20, 200, and 2,000 μg AFB1 kg−1. A significant decrease (P<0.05) in hemoglobin (Hb), red blood cells (RBC), and hematocrit (Hct) was observed in AFB1 exposure groups, with the lowest levels recorded in the 2000 μg AFB1 kg−1 treatment. A significant increase in mean white blood cells (WBC), neutrophils, and lymphocytes was observed in AFB1 exposure groups. No sex-related differences in RBC, WBC, lymphocytes, monocytes, and neutrophils levels were observed. However, hemoglobin and hematocrit values for female O. niloticus were significantly lower than those for male O. niloticus. Organosomatic indices showed that the relative liver, kidney, and spleen weights were significantly higher (P<0.05) in the AFB1 supplemented group than in the control group. However, the effect of aflatoxin on organosomatic indices does not depend on sex but rather depends on the dose of aflatoxin in the diet. These results provide useful information for monitoring changes in the health status of male and female O. niloticus.

scholarly journals Evaluation de la toxicité d’un aphrodisiaque ivoirien d’origine naturelle (aphro) chez le rat

2021 ◽  
Vol 15 (4) ◽  
pp. 1595-1604
Author(s):  
Moussa Gbogbo ◽  
Rufin Yao Kouadio ◽  
Félicité Tano-bla Aboli ◽  
Mama Kone ◽  
Elisée Kouassi Kporou ◽  
...  
Keyword(s):  
Body Weight ◽  
Blood Cells ◽  
Blood Platelets ◽  
Hematological Parameters ◽  
White Blood Cells ◽  
Wistar Rat ◽  
Control Group ◽  
World Population ◽  
Poids Corporel ◽  
Rate Of Increase

L’usage des plantes à des fins thérapeutiques est très ancien. De nos jours encore, elles sont utilisées par une frange partie de la population mondiale. La présente étude avait pour objectif d’étudier les effets toxiques de l'administration subaiguë d'un phytomédicament ivoirien Aphro vendu sur les marchés chez le rat Wistar albinos. Pour ce faire, le phytomédicament Aphro a été administré quotidiennement par voie orale à trois lots de rats, aux doses de 5,75 ; 11,5 et 23 mg/kg de poids corporel et cela pendant 28 jours. Le taux de croissance des rats, les paramètres hématologiques et biochimiques sanguins ont été étudiés. Les résultats de cette étude ont révélé qu’aux doses de 5,75 ; 11,5 et 23 mg/kg de poids corporel, le phytomédicament ne modifie pas de façon significative le taux d’accroissement de la masse corporelle et les paramètres hématologiques constitués du taux de globules rouges, de globules blancs, de plaquettes sanguines et le taux d’hémoglobine. Par ailleurs, des marqueurs hépatiques et lipidiques sériques des rats traités n'ont pas été perturbés par l’administration du phytomédicament comparativement au lot témoin. En revanche, la créatinine, l’un des marqueurs rénaux étudiés a connu une augmentation significative (p < 0,05) chez les rats traités avec le phytomédicament aux doses de 11,5 et 23 mg/kg de poids corporel par rapport au lot témoin. Cette étude a permis de montrer que l’usage prolongé et à doses élevées de Aphro pourrait entraîner des effets nocifs sur les reins.   English title: Assessment of the toxicity of an ivoirian natural aphrodisiac (aphro) on rat The use of plants for therapeutic purposes is very old. Even today, they are used by a part of the world population. The objective of the present study was to evaluate the toxic effects of the subacute administration of an ivorian phytomedicine Aphro sold in the markets in the albino Wistar rat. To do this, the phytomedicine Aphro was administered orally daily to three batches of rats, at doses of 5.75; 11.5 and 23 mg/kg of body weight for 28 days. Rats' growth rate, blood haematological and biochemical parameters were studied. The results of this study showed that at doses of 5.75; 11.5 and 23 mg/kg of body weight, the phytomedicine does not significantly modify the rate of increase in body mass and the hematological parameters consisting of the level of red blood cells, white blood cells, blood platelets and the level hemoglobin. Furthermore, hepatic and serum lipid markers of the treated rats were not disturbed by the administration of the phytomedicine compared to the control group. In contrast, creatinine, one of the renal markers studied, experienced a significant increase (p <0.05) in rats treated with the phytomedicine at doses of 11.5 and 23 mg / kg of body weight compared to the batch witness. This study showed that prolonged use and in high doses of Aphro could cause harmful effects on the kidneys.

scholarly journals Effect of silymarin supplementation on some productive and hematological parameters in meat type male Japanese quails

2019 ◽  
pp. 984
Author(s):  
Hristo Lukanov, Ivelina Pavlova ◽  
Veselin Ivanov, Todor Slavov, Yoana Petrova, Nadya Bozakova
Keyword(s):  
Body Weight ◽  
Growth Performance ◽  
Biochemical Parameters ◽  
Hematological Parameters ◽  
Control Group ◽  
Japanese Quails ◽  
Hematological And Biochemical Parameters ◽  
Experimental Group ◽  
Meat Type ◽  
Main Growth

A total of 90 14-day-old meat type male Japanese quails were included in the experiment and equally divided into 3 groups: control group (CG) without treatment, experimental group 1 (EG 0.5%), supplemented with silymarin 0.5% and experimental group 2 (EG 1%), supplemented with silymarin 1%. The aim of the current study was to establish the effect of supplementation with different doses of silymarin extract on the growth performance and some hematological parameters in male Japanese quails. Main growth performance (body weight, feed consumption and weight gain) were examined and FCR was calculated. Some hematological (WBC, RBC, HGB and HTC) and biochemical (triglycerides, AST and ALT) parameters were determined. The highest average body weight was observed in EG 0.5% group at 35-day-old age and the lowest in EG 1%, 239.61±2.96 g and 231.74±2.96 g respectively. The highest values of the weight gain were calculated in EG 0.5% group, 67.02±2.03 g during the first week of fattening and the lowest was observed in EG 1% group at the fifth week after hatching, 23.30±2.03 g respectively. The lowest values of FCR were observed during the first week of the trial, 2.42±0.08 kg/kg to 2.61±0.13 kg/kg in EG 1% and the control group respectively. The supplementation of 0.5% and 1% silymarin did not significantly change the studied hematological and biochemical parameters. A tendency of higher values of triglycerides and lower values of AST and ALT was observed in the groups, supplemented with silymarin compared to the controls. From the obtained results of the present study we can conclude that the silymarin supplementation at higher doses (0.5% and 1%) did not have effect on the main growth performance and some hematological and biochemical parameters of male Japanese quails.

scholarly journals Effect of Supplemental Cyanocobalamin on the Growth Performance and Hematological Indicators of the White Pekin Ducks from Hatch to Day 21

Animals ◽  
2019 ◽  
Vol 9 (9) ◽  
pp. 633
Author(s):  
Zaheer Ahmad ◽  
Ming Xie ◽  
Yongbao Wu ◽  
Shuisheng Hou
Keyword(s):  
Growth Performance ◽  
Blood Cells ◽  
Growth Parameters ◽  
Hematological Parameters ◽  
White Blood Cells ◽  
Daily Weight Gain ◽  
Control Group ◽  
Feed Conversion ◽  
Pekin Ducks ◽  
Hematological Indicators

The experiment was conducted to evaluate the requirement of cyanocobalamin of male Pekin ducks from hatch to 21 days of age. A total of three-hundred-eighty-four, one-day-old meat-type male Pekin ducks were randomly allocated to six treatments, i.e., dietary cyanocobalamin (vitamin B12) concentrations of 0.00, 0.02, 0.04, 0.06, 0.08 and 1.00 mg/kg, respectively in their feed. Each treatment had eight replicated pens with eight ducks for each pen. Feed and water were provided ad libitum. The experiment was conducted for 21 days. Different growth parameters including average daily weight gain (ADG), average daily feed intake (ADFI), feed conversion ratio (FCR), and hematological indicators were evaluated because, on the basis of hematological indicators, the health and nutritional status of an animal can be accessed. It is observed that supplemental cyanocobalamin has no significant effect on ADG, ADFI, and FCR but it improves hematological parameters such as white blood cells, red blood cells, and its indices and platelet counts compared to the control group (p < 0.05). On the basis of growth performance and hematological indicators it is concluded that 0.02 mg cyanocobalamin/kg of feed is the dietary requirement of male Pekin ducks from hatch to day 21 of age.

scholarly journals A 90-Day Oral Toxicity of Hydroethanolic Root Extract of Carissa spinarum in Wistar Rats

2021 ◽  
Vol 2021 ◽  
pp. 1-6
Author(s):  
Komlan M. Dossou-Yovo ◽  
Aboudoulatif Diallo ◽  
Povi Lawson-Evi ◽  
Yendubé T. Kantati ◽  
Tchin Darré ◽  
...  
Keyword(s):  
Body Weight ◽  
Biochemical Parameters ◽  
Wistar Rats ◽  
Hematological Parameters ◽  
Relative Weight ◽  
Control Group ◽  
Root Extract ◽  
Weight Changes ◽  
Oral Toxicity ◽  
Significant Difference

Background. Herbal medication is a worldwide and ancient practice, mostly in developing countries, where a large part of the population is involved in this practice. Hence, studies must be conducted to evaluate their safety and efficiency to avoid or prevent toxicological risks due to their usage. In Togo, Carissa spinarum is a medicinal plant belonging to Apocynaceae family, used as an aphrodisiac or to heal some ailments including malaria, sickle cell anemia, hypertension, pain, and asthma. Notwithstanding its several ethnomedicinal benefits, just a few toxicological data associated with its chronic use are available. Objective. Therefore, this study aims to assess the toxicity of an ethanolic root extract of Carissa spinarum in Wistar rats. Methods. The 90-day oral toxicity process following OECD TG 408 guidelines is used. Male Wistar rats received Carissa spinarum root hydroethanolic extract at 500 and 1000 mg/kg for 90 days by oral gavage. Body weight changes, hematological and blood biochemical parameters, organ weight changes, malondialdehyde as a lipoperoxidation marker expressed according to tissue proteins, and histopathology of vital organs were assessed. Results. No signs of toxicity or mortality were observed during the 90 days experiment. Hematological parameters have not shown any treatment-related abnormalities. According to biochemical parameters, an increase in the chloride ion level was observed at 1000 mg/kg p < 0.01 . There was no significant difference between the treated groups and the control group concerning the malondialdehyde concentration, body weight, and organ relative weight. No changes in necropsy and histopathology of vital organs associated with extract treatment were observed. Conclusion. The results indicated that an ethanolic root extract of Carissa spinarum does not cause adverse effects, which can lead to Wistar rats’ death after 90-day oral administration at 500 and 1000 mg.

scholarly journals HEMATOLOGICAL MODULATION IN REGULAR PRACTICE OF YOGA

2019 ◽  
Vol 3 (8) ◽  
Author(s):  
Deepak Goyal ◽  
Sadhana Agarwal
Keyword(s):  
Blood Pressure ◽  
Platelet Count ◽  
Blood Cells ◽  
Healthy Subjects ◽  
Hematological Parameters ◽  
White Blood Cells ◽  
Study Group ◽  
Hemoglobin Content ◽  
Regular Practice ◽  
Rbc Count

Background: A significant effect of yoga has been noticed in decreasing the blood glucose level, the heart rate, and systolic and diastolic blood pressure. Blood contains predominantly three types of blood cells including red blood cells (RBC), white blood cells (WBC) and Platelets. Methods- The study was carried out 100 volunteers. Study group comprised 50 male and 50 female healthy subjects of 18-20 years. Hematological parameters like total RBC Count, total W.B.C Count, hemoglobin content/dl and total Platelet count were determined by Improved Version of automated hematology auto-analyzer. For this Hemogram study, 5 ml of blood was collected in EDTA Vial under aseptic precautions. Results: Regular practice of yoga for 3 months significantly improved the R.B.C., W.B.C., Platelet count and Hb content. Conclusion- We concluded that regular practice of yoga for promotes trafficking of the stem cells from bone marrow and improve hematological parameters in anemia. Keywords: Yoga, hematological parameters, Regular.

scholarly journals HAEMATOLOGICAL AND BLOOD BIOCHEMICAL PARAMETERS OF PRE - AND POST LAMBING PERIODS FOR IRAQI NUAEMIE EWES

2021 ◽  
Vol 52 (4) ◽  
pp. 941-948
Author(s):  
Awad & et al.
Keyword(s):  
Blood Cells ◽  
Biochemical Parameters ◽  
Post Partum ◽  
Hematological Parameters ◽  
White Blood Cells ◽  
Physiological Status ◽  
Blood Samples ◽  
Blood Biochemical ◽  
Post Partum Period ◽  
Biochemical Assessment

The present study designed  to investigate the hematological and blood biochemical changes in pre and post lambing periods in Iraqi Nuaemie ewes. Ten Nuaemie ewes weighed 35-45 kg and aged between 2-3 years were reared in animal's house of Veterinary College / Tikrit University from October-2018 to March-2019, Ten ml of blood samples were collected from each animal during the periods of last gestation month, at lambing and 2 weeks thereafter, Two and half ml of blood samples were collected in EDTA- containing tubes to determine the hematological parameters and the remaining was used to separate serum and stored at -20 °c for blood biochemical assessment. The results   revealed decreased in total red blood cells, haemoglobin and packed cell volume during post lambing period. The total white blood cells count and neutrophils were decreased during the post-partum period, while the lymphocyte was decreased at the day of lambing (50±5.8%). The biochemical parameters exhibited lesser total protein concentrations at the day of lambing (6.5± 1.85 g/dl ) while greater glucose, cholesterol and triglyceride concentrations during post-partum period. The concentration of urea and creatinine increased during the pre-partum period whereas, LDL and HDL concentrations increased in post- lambing period. The minerals concentrations revealed lesser concentrations of Zink and iron during the post-partum period while, copper concentration was greater during similar period. In conclusion, the physiological status of animals have clearly effects on the haematological and biochemical parameters in Iraqi Nuaemie ewes.  

DYNAMICS OF PROTEIN METABOLISM AND ACTIVITY OF AMINOTRANSFERASES OF DOGS BY ADDING DIHYDROQUERCETIN

2016 ◽  
Vol 1 (2) ◽  
pp. 60-63
Author(s):  
Полищук ◽  
Sergey Polishchuk ◽  
Молянова ◽  
Galina Molyanova
Keyword(s):  
Body Weight ◽  
Blood Cells ◽  
Hematological Parameters ◽  
White Blood Cells ◽  
The Body ◽  
German Shepherd ◽  
Physiological Indicators ◽  
Formalin Edema ◽  
And Function ◽  
Experimental Group

The purpose of research is to increase protective and adaptive reactions, the service and the working potential of an organism of dogs through the use of DHQ. The article presents the results of an experiment to the effect of DHQ on the dynamics of hematological parameters of dogs blood. Dihydroquercetin – an active antioxidant, a natural scavenger of oxygen free radicals, hepatoprotective, has anti-inflammatory action due to limitations of the formalin edema and histamine, and inhibits the formation of serous fluid, pain killers, immunocorrectional properties. Due to the high complexing properties it displays the body of heavy metals, including radionuclides, it helps to restore the tone of blood vessels, normalization of the lipid spectrum of the blood and slows the development of atherosclerotic plaques. Investigations were carried out in Dogs State Service Ministry of I A of Russia zonal center in Samara Region by clinically healthy of dog breed German Shepherd, age 2-4 years with an average body weight of 30 kg on the background conditions and feeding, adopted by the enterprise. Dogs experimental group received Dihydroquercetin to 0.001 g/kg body weight dose once a day with food. When added to the basic diet Dihydroquercetin dog experimental group show an increase in indicators such as red blood cells – by 18.3% (p&#60;0.01), hemoglobin – by 11.7% (p &#60;0.01) hematocrit – 7.1% (p&#60;0.01), white blood cells – by 9.1% (p&#60;0.05) compared to control data. The research results give reason to believe that the use of dietary supplements in Dihydroquercetin in dogs diet dose 0.001 g/kg allows significantly increase the morphological and physiological indicators of animal organism. In this case a significant increase erythrocytes and hemoglobin and hematocrit indicates increased oxidative metabolism and function of the intensity of the blood in dogs treated with the drug, and increase in the blood indicates an increase in immune status.

scholarly journals Ameliorative Effect of Chronic Supplementation of Protocatechuic Acid Alone and in Combination with Ascorbic Acid in Aniline Hydrochloride Induced Spleen Toxicity in Rats

Scientifica ◽  
2016 ◽  
Vol 2016 ◽  
pp. 1-9 ◽  
Author(s):  
Upasana Khairnar ◽  
Aman Upaganlawar ◽  
Chandrashekhar Upasani
Keyword(s):  
Ascorbic Acid ◽  
Blood Cells ◽  
Protocatechuic Acid ◽  
Hematological Parameters ◽  
White Blood Cells ◽  
Feed Consumption ◽  
Control Group ◽  
Spleen Weight ◽  
Oxide Content ◽  
Aniline Hydrochloride

Background. Present study was designed to evaluate the protective effects of protocatechuic acid alone and in combination with ascorbic acid in aniline hydrochloride induced spleen toxicity in rats.Materials and Methods. Male Wistar rats of either sex (200–250 g) were used and divided into different groups. Spleen toxicity was induced by aniline hydrochloride (100 ppm) in drinking water for a period of 28 days. Treatment group received protocatechuic acid (40 mg/kg/day, p.o.), ascorbic acid (40 mg/kg/day, p.o.), and combination of protocatechuic acid (20 mg/kg/day, p.o.) and ascorbic acid (20 mg/kg/day, p.o.) followed by aniline hydrochloride. At the end of treatment period serum and tissue parameters were evaluated.Result. Rats supplemented with aniline hydrochloride showed a significant alteration in body weight, spleen weight, feed consumption, water intake, hematological parameters (haemoglobin content, red blood cells, white blood cells, and total iron content), tissue parameters (lipid peroxidation, reduced glutathione, and nitric oxide content), and membrane bound phosphatase (ATPase) compared to control group. Histopathology of aniline hydrochloride induced spleen showed significant damage compared to control rats. Treatment with protocatechuic acid along with ascorbic acid showed better protection as compared to protocatechuic acid or ascorbic acid alone in aniline hydrochloride induced spleen toxicity.Conclusion. Treatment with protocatechuic acid and ascorbic acid in combination showed significant protection in aniline hydrochloride induced splenic toxicity in rats.

scholarly journals Could the Vitacel R200 improve the Immune Response and Hemato-Biochemical Parameters of Rainbow Trout (Oncorhynchus mykiss) challenged with Aeromonas hydrophila?

2020 ◽  
Vol 10 (03) ◽  
pp. 332-336
Author(s):  
Ali Kane ◽  
Nabeel Al-Sharafi ◽  
Sabah Hamad
Keyword(s):  
Rainbow Trout ◽  
Oncorhynchus Mykiss ◽  
Aeromonas Hydrophila ◽  
Blood Cells ◽  
Biochemical Parameters ◽  
White Blood Cells ◽  
Control Group ◽  
Serum Total Protein ◽  
Rainbow Trout Oncorhynchus Mykiss ◽  
Immune Parameters

The fermentable fiber, Vitacel R200 is industrial compound cellulose exerting many beneficial health effects at the hosts. In this study, rainbow trout (Oncorhynchus mykiss) fingerling (120 ± 4.5 grams) were fed dietary 1% (10 g/kg feed) Vitacel R200 for 7 weeks, then challenged with Aeromonas hydrophila. Two weeks after the challenge, hemato-biochemical and immune parameters in the challenged fish were studied. The lysozyme and complement activity, as well as, white blood cells (WBCs), hemoglobin (Hb%), percentage of neutrophil and eosinophil in the fish fed Vitacel were significantly increased compared with the control group. Furthermore, the serum total protein, albumin, Na+, K+, P, and Ca++ concentrations in the fish fed diet containing 1% Vitacel were significantly increased, while alanine aminotransferase (ALT), alkaline phosphatase (ALP), and aspartate aminotransferase (AST), as well as, cortisol, cholesterol, and glucose concentration were significantly decreased in comparison to the control group. These results concluded that dietary Vitacel could improve the hemato-biochemical and immune parameters, as well as, the stress response in O. mykiss infected with A. hydrophila.

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