scholarly journals The Vegetative Receptor-Vascular Reflex (VRVR) – A New Key to Regeneration

2020 ◽  
Vol 11 ◽  
Author(s):  
Michael Ofner ◽  
Harald Walach
Keyword(s):  
Vascular Reflex

Supraspinal inhibition of a cutaneous vascular reflex in the cat

1964 ◽  
Vol 207 (2) ◽  
pp. 303-307 ◽  
Author(s):  
B. J. Prout ◽  
J. H. Coote ◽  
C. B. B. Downman
Keyword(s):  
Carotid Sinus ◽  
Spinal Reflexes ◽  
Descending Pathways ◽  
Skin Response ◽  
Reflex Arc ◽  
Vascular Reflex ◽  
Carotid Sinus Nerve Stimulation ◽  
Sympathetic Discharge ◽  
Stimulation Of ◽  
Cerebellar Stimulation

In cats anesthetized with chloralose-urethane mixture, stimulation of an afferent nerve evoked a vasoconstrictor reflex (VCR) and a galvanic skin response (GSR) in the pads of the feet. Stimulation of the ventromedial medullary reticular substance at the level of the obex abolished the VCR and the GSR. VCR could also be reduced by occlusion during prolonged stimulation of another spinal or visceral afferent pathway. Medulla stimulation was effective without itself causing a sympathetic discharge to the paw, showing that inhibition rather than occlusion was operative. Anterior cerebellar stimulation also inhibited the VCR. Carotid sinus nerve stimulation did not abolish the VCR. It is concluded that the effective mechanism includes a bulbospinal inhibitory path projecting on a spinal vasoconstrictor reflex arc. This arrangement is similar to the descending pathways inhibiting other spinal reflexes but the VCR-inhibitory path can be activated independently of them.

Cardiovascular reflexes following lesions in medullary reticular formation

1965 ◽  
Vol 208 (2) ◽  
pp. 283-288 ◽  
Author(s):  
John W. Manning
Keyword(s):  
Blood Pressure ◽  
Reticular Formation ◽  
Tissue Injury ◽  
Cardiac Activity ◽  
Cardiovascular Reflexes ◽  
Medullary Reticular Formation ◽  
Cardiovascular Reflex ◽  
Vascular Reflex ◽  
Inferior Olivary ◽  
Stimulation Of

In 19 anesthetized cats acute destruction of large portions of the medullary reticular formation was achieved with the aid of a radio-frequency lesion maker. Midline structures were spared by confining the lesions to the dorsolateral medulla. Tissue injury extended from a level rostral to the inferior olivary complex to the obex. These lesions in the medullary vasomotor area did not alter significantly the cardiovascular reflex adjustments to bilateral occlusion of the carotid arteries or to the stimulation of the central end of the cut sciatic nerve. In addition, an increase in contractile force, heart rate, and blood pressure evoked by stimulation of pressor areas in the posterior hypothalamus could be obtained following the lesions. The preparations were critically dependent upon supramedullary connections to maintain vascular tone and circulatory reflex adjustments, for decerebration in the lesioned animal brought about a reduction in blood pressure and a loss of vascular reflex responses. These findings suggest that supramedullary centers exert tonic as well as phasic influences on vascular and cardiac activity that is independent of the medullary vasomotor area.

Baric Peripheric Vascular Reflex with Local Effect

Cardiology ◽  
1961 ◽  
Vol 39 (5) ◽  
pp. 259-297 ◽  
Author(s):  
L·. Condorelli ◽  
A. Strano ◽  
G. Filocamo ◽  
A. Dagianti ◽  
M. Bartolo
Keyword(s):  
Local Effect ◽  
Vascular Reflex

Pulmonary alveolar-vascular reflex

1964 ◽  
Vol 19 (1) ◽  
pp. 105-112 ◽  
Author(s):  
D. F. J. Halmagyi ◽  
H. J. H. Colebatch ◽  
B. Starzecki ◽  
G. J. Horner
Keyword(s):  
Blood Flow ◽  
Pulmonary Hypertension ◽  
Pulmonary Circulation ◽  
Capillary Flow ◽  
Pulmonary Ventilation ◽  
Lung Compliance ◽  
Lung Mechanics ◽  
Reflex Response ◽  
Pulmonary Capillary ◽  
Vascular Reflex

Lung mechanics and pulmonary circulation were studied in lightly anesthetized, spontaneously breathing, supine sheep. Aerosol atropine restored lung compliance (Cl) in animals after fluid inhalation. Ventilation-perfusion relationship was studied by comparing Cl and effective pulmonary capillary blood flow (Qe = 100 minus venous admixture in per cent of cardiac output). The relation between Cl and Qe in unpremedicated sheep before and after fluid inhalation suggested homeostatic redistribution of blood flow away from nonventilated areas. Compensation for nonventilated areas was enhanced by severe pulmonary hypertension and abolished by atropine or isoproterenol; vagotomy had no effect. Homeostasis therefore appears to depend on a local reflex response of the parasympathetic nervous system— “alveolar-vascular reflex.” Pulmonary hypertension of generalized alveolar hypoxia was a different reaction not blocked by atropine. Consistent with this analysis, an infusion of acetylcholine increased pulmonary arterial resistance. The increase in Cl which followed atropine or isoproterenol indicated that in addition to surface forces, smooth muscle contraction may result in closure of lung units. lung mechanics and pulmonary circulation; fluid aspiration; atropine aerosol effect on lung compliance (Cl) after fluid inhalation; isoproterenol restored Cl; local homeostatic reflex response to pulmonary hypoxia; parasympathetic control of pulmonary ventilation; lung compliance (Cl) and effective pulmonary capillary flow (Qe) correlation Submitted on March 25, 1963

The Influence of Isoflurane on the Vascular Reflex Response to Lung Inflation in Dogs

1992 ◽  
Vol 76 (6) ◽  
pp. 972-978 ◽  
Author(s):  
Eugene Y. Cheng ◽  
Jonathan Kay ◽  
Sumio Hoka ◽  
Zeljko J. Bosnjak ◽  
Robert L. Coon ◽  
...  
Keyword(s):  
Reflex Response ◽  
Lung Inflation ◽  
Vascular Reflex

Participation of Vascular Reflex in Mucosal Swelling in Nasal Allergy

1982 ◽  
Vol 94 (1-6) ◽  
pp. 131-140 ◽  
Author(s):  
Akiyoshi Konno ◽  
Kiyoshi Togawa ◽  
Shigeki Nishihira
Keyword(s):  
Nasal Allergy ◽  
Vascular Reflex

scholarly journals The research progress on the mechanism of adenosine A1 receptor-mediated calcitonin gene-related peptide to relieve migraine

2019 ◽  
Vol 7 (11) ◽  
pp. 4429
Author(s):  
Zheng Hai Fei ◽  
Song Wei Wei ◽  
Chen Jin Bo ◽  
Zhang Ying
Keyword(s):  
Trigeminal Nerve ◽  
Vascular System ◽  
Calcitonin Gene Related Peptide ◽  
Adenosine A1 Receptor ◽  
Research Progress ◽  
Related Peptide ◽  
Calcitonin Gene ◽  
Adenosine A1 ◽  
Vascular Reflex ◽  
A1 Receptor

Currently, the pathogenesis of migraine is unclear. The trigeminal vascular reflex theory is the dominant pathogenesis theory, and its core parts are neurogenic inflammation and pain sensitisation. Calcitonin gene related peptide (CGRP) is the most powerful vasodilating peptide in brain circulation. It is also a marker of trigeminal nerve microvascular activation that plays a synergistic role in the pathogenesis of migraine. Adenosine A1 receptor (A1R) can inhibit the release of CGRP in the trigeminal nerve vascular system to alleviate migraine by mediating adenosine. This review summarises the progress of research on the alleviation of migraine by using A1R-mediated CGRP.

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