scholarly journals Adolescent Female Cannabinoid Exposure Diminishes the Reward-Facilitating Effects of Δ9-Tetrahydrocannabinol and d-Amphetamine in the Adult Male Offspring

2017 ◽  
Vol 8 ◽  
Author(s):  
George Pitsilis ◽  
Dimitrios Spyridakos ◽  
George G. Nomikos ◽  
George Panagis
Keyword(s):  
Adult Male ◽  
Male Offspring ◽  
Adolescent Female

Hypoxia or nutrient restriction during pregnancy in rats leads to progressive cardiac remodeling and impairs postischemic recovery in adult male offspring

2006 ◽  
Vol 20 (8) ◽  
pp. 1251-1253 ◽  
Author(s):  
Yi Xu ◽  
Sarah J. Williams ◽  
Darryl O'brien ◽  
Sandra T. Davidge ◽  
Yi Xu ◽  
...  
Keyword(s):  
Adult Male ◽  
Cardiac Remodeling ◽  
Male Offspring ◽  
Nutrient Restriction ◽  
Postischemic Recovery

Exposure to threshold doses of nicotine in utero: II. Neuroendocrine response to nicotine in adult male offspring

1994 ◽  
Vol 83 (2) ◽  
pp. 278-284 ◽  
Author(s):  
Russell E. Poland ◽  
Preetam Lutchmansingh ◽  
Denise Au ◽  
Chrissy Hsieh ◽  
Susan Afrane ◽  
...  
Keyword(s):  
Adult Male ◽  
In Utero ◽  
Male Offspring ◽  
Neuroendocrine Response ◽  
Threshold Doses

scholarly journals Increased exposure to sodium during pregnancy and lactation changes basal and induced behavioral and neuroendocrine responses in adult male offspring

2017 ◽  
Vol 5 (6) ◽  
pp. e13210 ◽  
Author(s):  
Marcia S. Silva ◽  
Fabiana Lúcio-Oliveira ◽  
Andre Souza Mecawi ◽  
Lucas F. Almeida ◽  
Silvia G. Ruginsk ◽  
...  
Keyword(s):  
Adult Male ◽  
Male Offspring ◽  
Pregnancy And Lactation ◽  
Neuroendocrine Responses

Caffeine programs hepatic SIRT1-related cholesterol synthesis and hypercholesterolemia via A2AR/cAMP/PKA pathway in adult male offspring rats

Toxicology ◽  
2019 ◽  
Vol 418 ◽  
pp. 11-21 ◽  
Author(s):  
Shuwei Hu ◽  
Kexin Liu ◽  
Hanwen Luo ◽  
Dan Xu ◽  
Liaobin Chen ◽  
...  
Keyword(s):  
Adult Male ◽  
Cholesterol Synthesis ◽  
Male Offspring ◽  
Pka Pathway

Maternal soy protein isolate diet during lactation programmes to higher metabolic risk in adult male offspring

2020 ◽  
Vol 71 (8) ◽  
pp. 954-964
Author(s):  
Poliana Guiomar de Almeida Brasiel ◽  
Maíra Schuchter Ferreira ◽  
Adriana Moura Vieira ◽  
Mariana Sarto Figueiredo ◽  
Patrícia Cristina Lisboa ◽  
...  
Keyword(s):  
Adult Male ◽  
Soy Protein ◽  
Soy Protein Isolate ◽  
Protein Isolate ◽  
Male Offspring ◽  
Metabolic Risk

Cross-Generational THC Exposure Alters Heroin Reinforcement in Adult Male Offspring

2020 ◽  
Vol 212 ◽  
pp. 107985 ◽  
Author(s):  
Briana J. Hempel ◽  
Madeline E. Crissman ◽  
Aikerim Imanalieva ◽  
Mariam Melkumyan ◽  
Tania D. Weiss ◽  
...  
Keyword(s):  
Adult Male ◽  
Male Offspring

scholarly journals Effects of Maternal Resveratrol on Maternal High-Fat Diet/Obesity with or without Postnatal High-Fat Diet

2020 ◽  
Vol 21 (10) ◽  
pp. 3428 ◽  
Author(s):  
Mei-Hsin Hsu ◽  
Jiunn-Ming Sheen ◽  
I-Chun Lin ◽  
Hong-Ren Yu ◽  
Mao-Meng Tiao ◽  
...  
Keyword(s):  
Insulin Resistance ◽  
Blood Pressure ◽  
Cognitive Impairment ◽  
Adult Male ◽  
High Fat Diet ◽  
Dorsal Hippocampus ◽  
Fetal Brain ◽  
Male Offspring ◽  
High Fat ◽  
Peripheral Insulin Resistance

To examine the effects of maternal resveratrol in rats borne to dams with gestational high-fat diet (HFD)/obesity with or without postnatal high-fat diet. We first tested the effects of maternal resveratrol intake on placenta and male fetus brain in rats borne to dams with gestational HFD/obesity. Then, we assessed the possible priming effect of a subsequent insult, male offspring were weaned onto either a rat chow or a HFD. Spatial learning and memory were assessed by Morris water maze test. Blood pressure and peripheral insulin resistance were examined. Maternal HFD/obesity decreased adiponectin, phosphorylation alpha serine/threonine-protein kinase (pAKT), sirtuin 1 (SIRT1), and brain-derived neurotrophic factor (BDNF) in rat placenta, male fetal brain, and adult male offspring dorsal hippocampus. Maternal resveratrol treatment restored adiponectin, pAKT, and BDNF in fetal brain. It also reduced body weight, peripheral insulin resistance, increased blood pressure, and alleviated cognitive impairment in adult male offspring with combined maternal HFD and postnatal HFD. Maternal resveratrol treatment restored hippocampal pAKT and BDNF in rats with combined maternal HFD and postnatal HFD in adult male offspring dorsal hippocampus. Maternal resveratrol intake protects the fetal brain in the context of maternal HFD/obesity. It effectively reduced the synergistic effects of maternal HFD/obesity and postnatal HFD on metabolic disturbances and cognitive impairment in adult male offspring. Our data suggest that maternal resveratrol intake may serve as an effective therapeutic strategy in the context of maternal HFD/obesity.

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