scholarly journals Plasmid-mediated quinolone resistance in Escherichia coli isolates from commercial broiler chickens and selection of fluoroquinolone-resistant mutants

2019 ◽  
Vol 98 (11) ◽  
pp. 5900-5907 ◽  
Author(s):  
Ryo Nishikawa ◽  
Toshiyuki Murase ◽  
Hiroichi Ozaki
2009 ◽  
Vol 53 (4) ◽  
pp. 1624-1627 ◽  
Author(s):  
Elise Launay ◽  
Nicolas Joram ◽  
Cédric Jacqueline ◽  
Anne Francoise Miegeville ◽  
Jocelyne Caillon ◽  
...  

ABSTRACT Pregnant rabbits were treated with ciprofloxacin alone or with gentamicin in a model of Escherichia coli chorioamnionitis, and the results were compared with those for untreated rabbits. The survival rate increased and the bacteremia decreased significantly in treated fetuses in comparison to controls (P = 0.003). Nevertheless, rapid selection of resistant mutants is a major limit to ciprofloxacin applications.


2007 ◽  
Vol 51 (11) ◽  
pp. 4163-4166 ◽  
Author(s):  
Aude Ferran ◽  
Véronique Dupouy ◽  
Pierre-Louis Toutain ◽  
Alain Bousquet-Mélou

ABSTRACT We demonstrate using an in vitro pharmacodynamic model that the likelihood of selection of Escherichia coli mutants resistant to a fluoroquinolone was increased when the initial size of the bacterial population, exposed to fluoroquinolone concentrations within the mutant selection window, was increased.


2019 ◽  
Vol 26 (1) ◽  
pp. 1-8
Author(s):  
Asmaa Abd Elatiff ◽  
Azza A. El-Sawah ◽  
Mohamed M. Amer ◽  
Al-Hussein M. Dahshan ◽  
Hala Salam ◽  
...  

2019 ◽  
Vol 25 (4) ◽  
pp. 517.e1-517.e4 ◽  
Author(s):  
H. Zhang ◽  
D. Zhao ◽  
J. Quan ◽  
X. Hua ◽  
Y. Yu

2018 ◽  
Vol 7 (4) ◽  
pp. 620-625 ◽  
Author(s):  
Azza A. EL-Sawah ◽  
AL Hussien M. Dahshan ◽  
El-Shaymaa El-Nahass ◽  
A.I. Abd El-Mawgoud

1992 ◽  
Vol 71 (1) ◽  
pp. 27-37 ◽  
Author(s):  
GABRIEL LEITNER ◽  
ZAHAVA UNI ◽  
AVIGDOR CAHANER ◽  
MICHAL GUTMAN ◽  
E. DAN HELLER

2011 ◽  
Vol 74 (9) ◽  
pp. 1558-1563 ◽  
Author(s):  
J. E. LINE ◽  
N. J. STERN ◽  
B. B. OAKLEY ◽  
B. S. SEAL

An instrument (TEMPO) has been developed to automate the most-probable-number (MPN) technique and reduce the effort required to estimate some bacterial populations. We compared the automated MPN technique with traditional microbiological plating methods and Petrifilm methods for estimating the total viable count of aerobic microorganisms (TVC), total coliforms (CC), and Escherichia coli populations (EC) on freshly processed broiler chicken carcasses (postchill whole carcass rinse [WCR] samples) and cumulative drip-line samples from a commercial broiler processing facility. Overall, 120 broiler carcasses, 36 prechill drip-line samples, and 40 postchill drip-line samples were collected over 5 days (representing five individual flocks) and analyzed by the automated MPN and direct agar plating and Petrifilm methods. The TVC correlation coefficient between the automated MPN and traditional methods was very high (0.972) for the prechill drip samples, which had mean log-transformed values of 3.09 and 3.02, respectively. The TVC correlation coefficient was lower (0.710) for the postchill WCR samples, which had lower mean log values of 1.53 and 1.31, respectively. Correlations between the methods for the prechill CC and EC samples were 0.812 and 0.880, respectively. The estimated number of total aerobes was generally greater than the total number of coliforms or E. coli recovered for all sample types (P < 2e−16). Significantly more bacteria were recovered from the prechill samples than from the postchill WCR or cumulative drip samples (P < 9.5e−12 and P < 2e−16, respectively). When samples below the limit of detection were excluded, 92.1% of the total responses were within a single log difference between the traditional plating or Petrifilm methods and the automated MPN method.


2005 ◽  
Vol 49 (3) ◽  
pp. 1190-1193 ◽  
Author(s):  
D. Gruson ◽  
S. Pereyre ◽  
H. Renaudin ◽  
A. Charron ◽  
C. Bébéar ◽  
...  

ABSTRACT Selection of resistant mutants in sequential subcultures with increasing concentrations of six and four different fluoroquinolones was studied for one reference strain each of Mycoplasma pneumoniae and Mycoplasma hominis, respectively. All fluoroquinolones tested selected for resistance, with alterations affecting the quinolone resistance-determining regions of the four target topoisomerase genes.


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