scholarly journals Effects of Feeding Fumonisin B1 Present in Fusarium moniliforme Culture Material and Aflatoxin Singly and in Combination to Turkey Poults

1995 ◽  
Vol 74 (8) ◽  
pp. 1295-1303 ◽  
Author(s):  
L.F. KUBENA ◽  
T.S. EDRINGTON ◽  
C. KAMPS-HOLTZAPPLE ◽  
R.B. HARVEY ◽  
M.H. ELISSALDE ◽  
...  
1995 ◽  
Vol 74 (2) ◽  
pp. 306-313 ◽  
Author(s):  
L.F. KUBENA ◽  
T.S. EDRINGTON ◽  
C. KAMPS-HOLTZAPPLE ◽  
R.B. HARVEY ◽  
M.H. ELISSALDE ◽  
...  

1997 ◽  
Vol 76 (2) ◽  
pp. 256-264 ◽  
Author(s):  
LF Kubena ◽  
TS Edrington ◽  
RB Harvey ◽  
TD Phillips ◽  
AB Sarr ◽  
...  

1993 ◽  
Vol 72 (3) ◽  
pp. 456-466 ◽  
Author(s):  
T.S. WEIBKING ◽  
D.R. LEDOUX ◽  
A.J. BERMUDEZ ◽  
J.R. TURK ◽  
G.E. ROTTINGHAUS ◽  
...  

1993 ◽  
Vol 5 (1) ◽  
pp. 75-83 ◽  
Author(s):  
Tandice S. Weibking ◽  
David R. Ledoux ◽  
Tom P. Brown ◽  
George E. Rottinghaus

The effects of dietary fumonisin B, were evaluated in young turkey poults. The experimental design consisted of 3 treatments, with 24 female turkey poults allotted randomly per treatment. Day-old poults were fed diets containing 0 mg (feed control), 100 mg, and 200 mg fumonisin B1/kg feed for 21 days. Body weight gains and efficiency of feed conversion decreased linearly with increasing dietary fumonisin. Liver, kidney, and pancreas weights increased linearly with increasing dietary fumonisin, and spleen and heart weights decreased. Serum aspartate aminotransferase levels increased with increasing dietary fumonisin, and serum cholesterol, alkaline phosphatase, mean cell volume, and mean cell hemoglobin all decreased. Biliary hyperplasia, hypertrophy of Kupffer's cells, thymic cortical atrophy, and moderate widening of the proliferating and degenerating hypertrophied zones of tibial physes were present in poults fed diets containing fumonisin B1. Results indicate that fumonisin B1, from Fusarium moniliforme culture material, is toxic in young poults, and the poult appears to be more sensitive to fumonisin than the broiler chick.


1994 ◽  
Vol 77 (2) ◽  
pp. 522-525 ◽  
Author(s):  
Paul E Nelson ◽  
Jean H Juba ◽  
P Frank Ross ◽  
Larry G Rice

Abstract Fumonisins were produced by strains of Fusarium moniliforme and F. proliferatum on a medium consisting of 500 g yellow corn kernels and 500 mL distilled water added to a 30.5 × 61 cm autoclavable polyethylene bag. The corn was inoculated by drawing a suspension from a lyophilized culture into a sterile 5 mL syringe fitted with a 19 gauge needle and injecting 1 mL through the side of each polyethylene culture bag. Bags of inoculated com were incubated in the dark at 20° to 22°C for 4 weeks. Seven to 8 days after inoculation, holes were punched near the tops of the bags to promote aeration. After a 4 week incubation, cultures were soaked in chloroform–acetone (50 + 50, v/v) in 4 L flasks overnight to kill fungus and to remove water. Next, the culture media was filtered through 2 mm nylon mesh screens and air dried from 24 to 48 h. Fumonisin concentrations were determined by liquid chromatography/o-phthalaldialdehyde fluorescence. Confirmation was by gas chromatography/mass spectrometry. We observed that the 3 most important factors in the production of fumonisins in bulk corn cultures were temperature control, moisture, and aeration. Extraction by acetonitrile–water (50 + 50, v/v) for 30 min produced the highest yields of fumonisins. Measurable concentrations were reduced by as much as 50% when culture material was heated at 50°C overnight. Fusarium moniliforme strains consistently produced fumonisin B1 as the major component, but some strains of F. proliferatum produced fumonisin B2 and/or fumonisin B3 at higher concentrations than fumonisin B1. Results were calculated on the basis of dried culture material.


Toxicology ◽  
2001 ◽  
Vol 163 (1) ◽  
pp. 11-22 ◽  
Author(s):  
J.D Bailly ◽  
G Benard ◽  
J.-Y Jouglar ◽  
S Durand ◽  
P Guerre

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