scholarly journals The Effect of Non-Protein Energy Source and Age on the Blood Glucose Level and the muscle glycogen Content of Young Chicks

1975 ◽  
Vol 54 (4) ◽  
pp. 1327-1329 ◽  
Author(s):  
R.W. Rosebrough ◽  
J.J. Begin
2017 ◽  
Vol 6 (1) ◽  
pp. 38-44
Author(s):  
Chinyelu C. Osigwe ◽  
◽  
Peter A. Akah ◽  
Chukwuemeka S. Nworu ◽  
Festus B. C. Okoye ◽  
...  

The leaves of Newbouldia laevis is traditionally used to treat diabetes mellitus in southeast Nigeria. The apigenin isolated from the methanol fraction of dichloromethane/methanol (1:1) extract of the leaves was evaluated for antidiabetic and antihyperglycemic activity in alloxan-induced diabetic rats and on normal rats. Treatment of alloxan-diabetic rats with the compound (apigenin) significantly (p < 0.05) reduced blood glucose, and increased the liver and muscle glycogen content. The adrenaline-induced elevation of blood glucose of normal rats was significantly (p < 0.05) reduced by the isolated compound. These results suggest that apigenin may be the anti-diabetic principle in the leaves of Newbouldia laevis..


1993 ◽  
Vol 74 (4) ◽  
pp. 1921-1927 ◽  
Author(s):  
A. N. Bosch ◽  
S. C. Dennis ◽  
T. D. Noakes

This study compared liver glucose turnover, blood glucose oxidation, and muscle glycogen utilization in 15 male endurance-trained cyclists who rode for 180 min at 70% of maximal O2 consumption in either a carbohydrate-(CHO) loaded (CL) or a non-CHO-loaded (NL) state. Total CHO oxidation during exercise was similar in the CL and NL subjects (492 +/- 77 vs. 448 +/- 43 g, respectively), as were blood glucose oxidation (103 +/- 19 vs. 99 +/- 7 g, respectively) and liver glucose appearance (110 +/- 15 vs. 127 +/- 16 g, respectively). However, total muscle glycogen utilization was greater in CL than NL subjects (134 +/- 11 vs. 95 +/- 12 mmol/kg wet wt; P < 0.05), the former of which had higher muscle glycogen content at the start (194 +/- 4 vs. 124 +/- 7 mmol/kg wet wt; P < 0.05) and throughout the trial. Whereas high rates of muscle glycogen breakdown were maintained throughout the trial in CL subjects, rates of muscle glycogenolysis in NL subjects decreased to 26 mmol.kg wet wt-1.h-1 after 60 min of exercise (P < 0.05) when their muscle glycogen content had declined to 70 mmol/kg wet wt. Comparable rates of blood glucose and overall CHO oxidation in CL and NL subjects, despite a slowing of muscle glycogenolysis in the NL group, could be explained by an accelerated breakdown of glycogen in the nonworking muscles to redistribute CHO (lactate) to the working muscles for oxidation.(ABSTRACT TRUNCATED AT 250 WORDS)


INDIAN DRUGS ◽  
2012 ◽  
Vol 49 (08) ◽  
pp. 45-50
Author(s):  
N. A Khatib ◽  
◽  
P. A Patil ◽  
P. Ismail

Methanol extract of Feronia elephantum fruit at a dose of 400 mg/kg twice a day, was evaluated for its insulin secretagogue potential in streptozotocin (STZ) 50 mg/kg induced diabetic rats. Treatment showed significant (P<0.001) decrease in blood glucose and significant (P<0.001) increase in seruminsulin, hepatic, muscle glycogen content and restoration of disturbed dyslipidemia. Result obtained from the present study indicates that methanol extract of Feronia elephantum fruit has insulin secretagogue potential in STZ induced diabetic rats.


2021 ◽  
Vol 12 ◽  
Author(s):  
Sonia Métayer-Coustard ◽  
Sophie Tesseraud ◽  
Christophe Praud ◽  
David Royer ◽  
Thierry Bordeau ◽  
...  

In chickens, a divergent selection on the Pectoralis major pHu allowed the creation of the pHu+ and pHu− lines, which represent a unique model for studying the biological control of carbohydrate storage in muscle. The present study aimed to describe the early mechanisms involved in the establishment of pHu+ and pHu− phenotypes. At hatching, pHu+ chicks were slightly heavier but exhibited lower plasma glucose and triglyceride and higher uric acid. After 5 days, pHu+ chicks exhibited higher breast meat yield compared to pHu− while their body weight was no different. At both ages, in vivo muscle glycogen content was lower in pHu+ than in pHu− muscles. The lower ability of pHu+ chicks to store carbohydrate in their muscle was associated with the increased expression of SLC2A1 and SLC2A3 genes coding glucose transporters 1 and 3, and of CS and LDHα coding key enzymes of oxidative and glycolytic pathways, respectively. Reduced muscle glycogen content at hatching of the pHu+ was concomitant with higher activation by phosphorylation of S6 kinase 1/ribosomal protein S6 pathway, known to activate protein synthesis in chicken muscle. In conclusion, differences observed in muscle at slaughter age in the pHu+ and pHu− lines are already present at hatching. They are associated with several changes related to both carbohydrate and protein metabolism, which are likely to affect their ability to use eggs or exogenous nutrients for muscle growth or energy storage.


2019 ◽  
pp. 52-56
Author(s):  
Yu.F. Glukhov ◽  
N.V. Krutikov ◽  
A.V. Ivanov ◽  
N.P. Muravskaya

We have studied and analyzed status and metrological supervision of blood glucose monitors, individual devices for a person’s blood glucose level measurement. It has been indicated that nowadays blood glucose monitors like other individual devices for medical measurement are not allowed to be involved in telemedicine public service. This accounts for absence of metrological supervision with these measurement devices in telemedicine. In addition, the key problem is absence of safe methods and means of remote verificaition, calibration and transmission of measurement data to health care centers. The article offers a remote test method for blood glucose monitors using a number of resistors with values correlating with measured blood glucose level. The available method has been successfully trialed in real practice.


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