scholarly journals Prevalence of Skin Manifestations in Diabetes Mellitus at King Abdulaziz University Hospital

2012 ◽  
Vol 2 (1) ◽  
pp. 19-22
Author(s):  
Sameer KH. Zimmo
Keyword(s):  
Diabetes Mellitus ◽  
Type Ii Diabetes ◽  
University Hospital ◽  
Skin Manifestations ◽  
High Prevalence ◽  
Patients With Diabetes ◽  
Common Skin ◽  
King Abdulaziz University ◽  
Diabetic Population ◽  
The Common

Background: The prevalence of diabetes in Saudi Arabia is now one of the highest in the world, with the rise in prevalence of Type II diabetes. Patients with diabetes mellitus commonly suffer from a wide variety of cutaneous disorders. Aims: This study estimates the prevalence of skin manifestations in patients with diabetes mellitus, at King Abdulaziz University Hospital. Materials and Methods: Five hundred and fifty-eight patients with the diagnosis of diabetes, attending the dermatologic and diabetic clinic were included in this study. Results: The common skin disorders were: xerosis (74.7%), pruritus (38.2%), diabetic dermopathy (30.1%), finger pebbles (25.6%), and thickened skin (22.2%). Conclusion: Skin manifestations in diabetics are common. High prevalence of xerosis in our diabetic population is significant and further studies are recommended.

scholarly journals Prevalence of Skin Manifestations in Diabetes Mellitus at King Abdulaziz University Hospital

2012 ◽  
Vol 2 (1) ◽  
pp. 19-22
Author(s):  
Sameer KH. Zimmo
Keyword(s):  
Diabetes Mellitus ◽  
Type Ii Diabetes ◽  
University Hospital ◽  
Skin Manifestations ◽  
High Prevalence ◽  
Patients With Diabetes ◽  
Common Skin ◽  
King Abdulaziz University ◽  
Diabetic Population ◽  
The Common

Background: The prevalence of diabetes in Saudi Arabia is now one of the highest in the world, with the rise in prevalence of Type II diabetes. Patients with diabetes mellitus commonly suffer from a wide variety of cutaneous disorders. Aims: This study estimates the prevalence of skin manifestations in patients with diabetes mellitus, at King Abdulaziz University Hospital. Materials and Methods: Five hundred and fifty-eight patients with the diagnosis of diabetes, attending the dermatologic and diabetic clinic were included in this study. Results: The common skin disorders were: xerosis (74.7%), pruritus (38.2%), diabetic dermopathy (30.1%), finger pebbles (25.6%), and thickened skin (22.2%). Conclusion: Skin manifestations in diabetics are common. High prevalence of xerosis in our diabetic population is significant and further studies are recommended.

scholarly journals Reducing the risk of heart failure in diabetes mellitus: review of new therapeutics

2020 ◽  
Vol 9 (4) ◽  
pp. 660
Author(s):  
Shreeharsh Godbole ◽  
Shreerang Godbole
Keyword(s):  
Diabetes Mellitus ◽  
Heart Failure ◽  
Glycemic Control ◽  
Long Term Outcomes ◽  
Increased Risk ◽  
High Prevalence ◽  
Patients With Diabetes ◽  
Diabetic Population ◽  
Glucose Transport Protein

Diabetes mellitus (DM) and heart failure (HF) are closely related: patients with diabetes have an increased risk of developing HF and those with HF are at higher risk of developing diabetes. When the two diseases are considered individually, HF has a much poorer prognosis than diabetes mellitus; therefore, treatment of HF is a priority in these group of patients. There are many drugs now available to achieve glycemic control in individuals with DM. However, as we enter an era of personalization in the management of DM, the next challenge will be the identification of therapeutic strategies that will not only achieve and maintain glycemic control, but that will also reverse existing complications. Given the high prevalence of HF in DM, there is a strong imperative to advance this field, with the view of identifying robust strategies that will not only improve long-term outcomes in subjects with DM and HF but also limit the likelihood of developing HF in the first place. Newer therapies like sodium- glucose transport protein- 2 inhibitors (SGLT-2 I) and sacubitril or valsartan have shown potential benefit for reducing the risk of heart failure in diabetic population. This review will summarize the new therapeutics to reduce the risk of HF in patients with DM.

High prevalence of NASH among Mexican American females with type II diabetes mellitus

2001 ◽  
Vol 120 (5) ◽  
pp. A117 ◽  
Author(s):  
Nyingi M. Kemmer ◽  
Kevin H. McKinney ◽  
Shu-Yuan Xiao ◽  
Harbans Singh ◽  
Richard Murray ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type Ii Diabetes ◽  
Mexican American ◽  
Type Ii Diabetes Mellitus ◽  
Type Ii ◽  
High Prevalence

Adjuvant Supplementation with L-Carnitine in Diabetic Population and its effects on Lipid Parameters

2021 ◽  
Vol 15 (8) ◽  
pp. 2017-2019
Author(s):  
Rao Salman Aziz ◽  
Usman Saeed ◽  
Nasim Aslam Ghumman ◽  
Muhammad Arshad ◽  
Asif Sohail ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Triglyceride Level ◽  
Clinical Care ◽  
Diabetic Patients ◽  
Healthy Population ◽  
Patients With Diabetes ◽  
Diabetic Population ◽  
Large Discount ◽  
The Impact ◽  
Lipid Parameters

Background: Diabetes is a complicated disease requires continuous clinical care, to govern blood sugar. Aim: To decides the impact of management of L carentin to diabetics at the lipid profile. Methods: This study turned into performed on 120 diabetic Patients had been decided on from endocrinology and diabetes, inside decided on standards. The Patients distributed into three Strata (1st Strata of healthy population and two Strata of patients with diabetes who were on metformin and glibenclamide, one Strata took a L carnitine in a dose of 1000 mg TDS and a Strata dealing with a placebo for a period of ninety days). Results: It is observed those who are on Lcarnitine, confirmed a large discount (p <0.05) with inside the triglyceride level, at the same time as no large adjustments had been located withinside the level of cholesterol and HDL and LDL. Conclusion: These study outcomes that management of L carentin improved profile of lipid in type-2diabetic Patients. Keyword: Dyslipidemia, Diabetes mellitus (DM), l-carnitine (LC).

scholarly journals The Prevalence of Nondiabetic Renal Diseases in Patients with Diabetes Mellitus in the University Hospital of Ribeirão Preto, São Paulo

2020 ◽  
Vol 2020 ◽  
pp. 1-6
Author(s):  
Diego Agra Souza ◽  
Gyl Eanes Barros Silva ◽  
Igor Lima Fernandes ◽  
Dyego José Araújo de Brito ◽  
Monique Pereira Rêgo Muniz ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Membranous Glomerulonephritis ◽  
Sao Paulo ◽  
Group Iv ◽  
University Hospital ◽  
Renal Diseases ◽  
Group I ◽  
Patients With Diabetes ◽  
The University ◽  
Time Since Diagnosis

Objective. To evaluate the prevalence of nondiabetic renal diseases (NDRDs) in renal biopsies of patients with diabetes mellitus (DM) in the University Hospital of Ribeirão Preto, São Paulo. Research Design and Methods. We conducted a retrospective study including kidney biopsies performed in diabetic patients between 1987 and 2013. We evaluated 79 biopsies during this period. The primary variable was the prevalence of NDRD in patients with DM. The secondary variables were the presence of systemic arterial hypertension (SAH), hematuria, time since diagnosis of DM, serum creatinine, and proteinuria levels. The cases were divided into the following groups: isolated diabetic nephropathy (DN—group I), isolated nondiabetic renal diseases (NDRD—group II), associated NDRD/DN (group III), and associated NDRD+NDRD/DN (group IV). Results. Most of the patients (58.22%) presented only alterations arising from DN. NDRDs were present in 41.77% of the patients. Membranous glomerulonephritis (30.3%) and IgA nephropathy (24.24%) were the most prevalent NDRDs. We found no differences between female and male patients with NDRD when assessing the secondary variables. A time since diagnosis of five years or less revealed a statistical difference (p=0.0005) in the comparison between the isolated DN (group I) and the NDRD+NDRD/DN (group IV). The other secondary variables were not significant in the comparison of the groups. Conclusions. We concluded that the prevalence of NDRD is 41.77%. Membranous glomerulonephritis was the most prevalent NDRD in our study. We also conclude that the probability of the presence of NDRD with or without concomitant DN is greater for patients who had biopsies with a time since diagnosis of five years or less. A time since diagnosis of ten years or more does not allow the exclusion of the presence of NDRD.

scholarly journals Demanda de pacientes com diabetes mellitus em unidade de urgência de um Hospital Universitário/ Profile of patients with diabetes mellitus in the emergency unit of a University Hospital

2016 ◽  
Vol 15 (2) ◽  
pp. 312 ◽  
Author(s):  
Tatiane Aparecida Martins ◽  
Claudia Benedita Dos Santos ◽  
Manoel Antônio dos Santos ◽  
Flávia Fernanda Luchetti Rodrigues ◽  
Cesar Eduardo Pedersoli ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
University Hospital ◽  
Emergency Unit ◽  
Patients With Diabetes

Este é um estudo transversal, cujo objetivo foi identificar o perfil de pacientes com diabetes mellitus em Unidade de Urgência. A amostra probabilística foi constituída por 247 pacientes de um hospital do interior paulista, Brasil, em 2009. Um formulário estruturado, contendo variáveis sociodemográficas, clínicas e relacionadas às orientações de enfermagem, oferecidas na alta hospitalar, foi utilizado para obtenção dos dados nos prontuários de saúde. Para análise dos dados, foi utilizada estatística descritiva. Os resultados mostraram que os pacientes admitidos eram predominantemente do gênero feminino (53,4%), brancos (79,8%), com baixa escolaridade (76,6%) e idade entre 58 e 77 anos (50,2%); média de 62 anos e desvio-padrão de 15,3 anos. Quanto à procura pelo atendimento, os diagnósticos mais prevalentes foram: problemas cardiovasculares (22,3%) e cerebrovasculares (13%). O diabetes foi considerado motivo secundário para admissão no serviço, o primário foi relacionado apenas à queixa principal do paciente. O tempo de internação foi, em média, de quatro dias, com mediana de nove dias e desvio-padrão de 21,7. As orientações de enfermagem registradas em prontuário na alta hospitalar se restringiram aos retornos ambulatoriais. Há necessidade de melhor articulação da rede de atenção primária e hospitalar para redução da demanda evitável de pacientes com diabetes em unidade de urgência.

Glycoxidation, and protein and DNA oxidation in patients with diabetes mellitus

1998 ◽  
Vol 95 (3) ◽  
pp. 331-337 ◽  
Author(s):  
K. KRAPFENBAUER ◽  
R. BIRNBACHER ◽  
H. VIERHAPPER ◽  
K. HERKNER ◽  
D. KAMPEL ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Diabetes Mellitus ◽  
Hydroxyl Radical ◽  
Protein Oxidation ◽  
Type Ii Diabetes ◽  
Dna Oxidation ◽  
Type I ◽  
Type Ii ◽  
Patients With Diabetes ◽  
Radical Attack

1.The role of oxidative stress in the pathogenesis of the diabetic state is being investigated extensively. Although oxidative stress has been reported in terms of glycoxidation, protein oxidation and DNA oxidation in diabetes mellitus, oxidation parameters have not been determined in parallel on the same study population. 2.We studied 24 patients with diabetes mellitus (14 patients with Type I diabetes with a mean age of 62.3±6.3 years and 10 patients with Type II diabetes aged 67.3±5.9 years) and compared them with age-matched non-diabetic controls. Urinary o-tyrosine, 8-hydroxy-2′-deoxyguanosine and pentosidine measurements by HPLC were made on two occasions (t1 and t2). 3.A clear statistical difference was found between diabetic patients and controls at t1 or t2 for 8-hydroxy-2′-deoxyguanosine and pentosidine, but not for o-tyrosine. No significant correlations were found between clinical and other laboratory parameters except high-density lipoprotein and uric acid. We revealed significantly increased glycoxidation and DNA oxidation in patients with Type I and Type II diabetes, but protein oxidation was not different from controls. 4.The finding of increased glycoxidation reflects increased oxidation of the carbohydrate moiety, whereas the increased levels of oxidized DNA may also be interpreted as due to increased DNA repair. The increased 8-hydroxy-2′-deoxyguanosine does not indicate the generation of an individual active oxygen species, but DNA could have been oxidized simply by alkenals from lipid peroxidation, as e.g. malondialdehyde. As no difference in protein oxidation (i.e. o-tyrosine) between diabetics and controls could be revealed, the oxidation of DNA by hydroxyl radical attack is unlikely, as o-tyrosine was proposed as a marker for hydroxyl radical attack. Therefore, the message is that increased glycoxidation can be confirmed, protein oxidation does not appear to take place and increased DNA oxidation is still not proven, as increased 8-hydroxy-2′-deoxyguanosine may simply reflect repair.

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