scholarly journals The Prevalence of Nondiabetic Renal Diseases in Patients with Diabetes Mellitus in the University Hospital of Ribeirão Preto, São Paulo

2020 ◽  
Vol 2020 ◽  
pp. 1-6
Author(s):  
Diego Agra Souza ◽  
Gyl Eanes Barros Silva ◽  
Igor Lima Fernandes ◽  
Dyego José Araújo de Brito ◽  
Monique Pereira Rêgo Muniz ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Membranous Glomerulonephritis ◽  
Sao Paulo ◽  
Group Iv ◽  
University Hospital ◽  
Renal Diseases ◽  
Group I ◽  
Patients With Diabetes ◽  
The University ◽  
Time Since Diagnosis

Objective. To evaluate the prevalence of nondiabetic renal diseases (NDRDs) in renal biopsies of patients with diabetes mellitus (DM) in the University Hospital of Ribeirão Preto, São Paulo. Research Design and Methods. We conducted a retrospective study including kidney biopsies performed in diabetic patients between 1987 and 2013. We evaluated 79 biopsies during this period. The primary variable was the prevalence of NDRD in patients with DM. The secondary variables were the presence of systemic arterial hypertension (SAH), hematuria, time since diagnosis of DM, serum creatinine, and proteinuria levels. The cases were divided into the following groups: isolated diabetic nephropathy (DN—group I), isolated nondiabetic renal diseases (NDRD—group II), associated NDRD/DN (group III), and associated NDRD+NDRD/DN (group IV). Results. Most of the patients (58.22%) presented only alterations arising from DN. NDRDs were present in 41.77% of the patients. Membranous glomerulonephritis (30.3%) and IgA nephropathy (24.24%) were the most prevalent NDRDs. We found no differences between female and male patients with NDRD when assessing the secondary variables. A time since diagnosis of five years or less revealed a statistical difference (p=0.0005) in the comparison between the isolated DN (group I) and the NDRD+NDRD/DN (group IV). The other secondary variables were not significant in the comparison of the groups. Conclusions. We concluded that the prevalence of NDRD is 41.77%. Membranous glomerulonephritis was the most prevalent NDRD in our study. We also conclude that the probability of the presence of NDRD with or without concomitant DN is greater for patients who had biopsies with a time since diagnosis of five years or less. A time since diagnosis of ten years or more does not allow the exclusion of the presence of NDRD.

scholarly journals Electroneurographic parameters in patients with metabolic syndrome

2014 ◽  
Vol 4 (1) ◽  
pp. 45-49
Author(s):  
Suljo Kunić ◽  
Emir Tupković ◽  
Mediha Nišić ◽  
Semiha Salihović
Keyword(s):  
Diabetes Mellitus ◽  
Metabolic Syndrome ◽  
Glycemic Control ◽  
Action Potential ◽  
Median Nerve ◽  
Ulnar Nerve ◽  
Sensory Nerve ◽  
Group I ◽  
Patients With Diabetes ◽  
Group Ii

Introduction: The aim of this study was to measure electroneurographic (ENG) parameters of the median and ulnar nerve in patients with metabolic syndrome and to determine whether the large imbalance in glycemic control came to neuropathic changes to the template.Methods: The study included 100 patients with metabolic syndrome diagnosed according to the criteria of the National Cholesterol Education Program - Adult Treatment Panel III (NCEP-ATP III). The patients were divided into two groups. Group I – patients with normal glycemic control and Group II - patients with diabetes mellitus for up to five years. We measured sensory conductive velocity (SCV), the amplitude of sensory nerve action potential (SNAP), motor conductive velocity (MCV), terminal motor latency (TML) and compose muscle action potential after distal stimulation (CMAP-I) and after proximal stimulation (CMAP-II) for the ulnar and median nerve.Results: Sensory and motor parameters in Group II were amended to neuropathic pattern compared to Group I. There were significant differences in: SNAP amplitude for all tested nerves, SCV values for both left and right median and ulnar nerve; MCV and TML for left median nerve; MCV, TML and CMAP-I for right median nerve area; MCV and TML for left ulnar nerve; MCV, CMAP-I and CMAP-II for right ulnar nerve area.Conclusion: Patients with metabolic syndrome and diabetes mellitus duration of five years have the significant changes in sensory and motor peripheral nerves. Neuropathic changes are possible in patients with metabolic syndrome and normal glycemic control.

scholarly journals Parameters of cardiac hemodynamics in patients with diabetes mellitus with impairment of renal function

HYPERTENSION ◽  
2021 ◽  
Vol 14 (4) ◽  
pp. 5-10
Author(s):  
I.I. Topchiy ◽  
O.N. Kirienko ◽  
P.S. Semyonovykh ◽  
D.O. Kirienko ◽  
O.I. Tsygankov ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Renal Function ◽  
Structural Parameters ◽  
Left Ventricular ◽  
Control Group ◽  
Group I ◽  
Patients With Diabetes

Currently, diabetes mellitus (DM) is a complex global problem, which is increasing every year. So, in 2019, diabetes mellitus was detected in 463 million adults (from 20 to 79 years old) in the world. And the main cause of death in patients with diabetes mellitus is cardiovascular complications. The study was aimed investigate the features of functional and structural changes in the heart in patients with type 2 diabetes mellitus and nephropathy. A total of 98 patients with type 2 diabetes mellitus were examined, out of which 78 patients had diabetic nephropathy (DN) of varying severity. The control group consisted of 20 healthy patients. After a clinical examination, depending on the state of renal function, all patients were divided into the following groups: group I — patients with type 2 diabetes mellitus without signs of nephropathy (n = 36), group II — patients with type 2 diabetes mellitus with normal glomerular filtration rate (GFR) and albuminuria (n = 33), group III — patients with type 2 diabetes mellitus with decreased GFR and albuminuria (n = 29). To study changes in hemodynamics and structural parameters of the heart, patients underwent transthoracic echocardiography on an ULTIMA PA ultrasound machine (Radmir, Ukraine) using a sectoral phased transducer with a frequency range of 2–3 MHz according to the standard technique based on the recommendations of the American Echocardiographic Society. To determine indexing indicators, the patients underwent anthropometric measurements. Patients with DN and albuminuria and decreased GFR showed an increase in the linear dimensions of the heart in comparison with controls and patients without signs of nephropathy. With DN, patients have a significant increase in left ventricular mass and a significant increase in the detection rate of left ventricular hypertrophy up to 91.3 % in patients with albuminuria and preserved renal function and up to 100 % with a decrease in GFR.

scholarly journals Demanda de pacientes com diabetes mellitus em unidade de urgência de um Hospital Universitário/ Profile of patients with diabetes mellitus in the emergency unit of a University Hospital

2016 ◽  
Vol 15 (2) ◽  
pp. 312 ◽  
Author(s):  
Tatiane Aparecida Martins ◽  
Claudia Benedita Dos Santos ◽  
Manoel Antônio dos Santos ◽  
Flávia Fernanda Luchetti Rodrigues ◽  
Cesar Eduardo Pedersoli ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
University Hospital ◽  
Emergency Unit ◽  
Patients With Diabetes

Este é um estudo transversal, cujo objetivo foi identificar o perfil de pacientes com diabetes mellitus em Unidade de Urgência. A amostra probabilística foi constituída por 247 pacientes de um hospital do interior paulista, Brasil, em 2009. Um formulário estruturado, contendo variáveis sociodemográficas, clínicas e relacionadas às orientações de enfermagem, oferecidas na alta hospitalar, foi utilizado para obtenção dos dados nos prontuários de saúde. Para análise dos dados, foi utilizada estatística descritiva. Os resultados mostraram que os pacientes admitidos eram predominantemente do gênero feminino (53,4%), brancos (79,8%), com baixa escolaridade (76,6%) e idade entre 58 e 77 anos (50,2%); média de 62 anos e desvio-padrão de 15,3 anos. Quanto à procura pelo atendimento, os diagnósticos mais prevalentes foram: problemas cardiovasculares (22,3%) e cerebrovasculares (13%). O diabetes foi considerado motivo secundário para admissão no serviço, o primário foi relacionado apenas à queixa principal do paciente. O tempo de internação foi, em média, de quatro dias, com mediana de nove dias e desvio-padrão de 21,7. As orientações de enfermagem registradas em prontuário na alta hospitalar se restringiram aos retornos ambulatoriais. Há necessidade de melhor articulação da rede de atenção primária e hospitalar para redução da demanda evitável de pacientes com diabetes em unidade de urgência.

scholarly journals Study of Salivary Stress Factor Activity in Patients with Diabetes Mellitus During the Period of Adaptation to Complete Removable Laminar Dentures

2020 ◽  
Vol 27 (3) ◽  
pp. E202038
Author(s):  
Lyubov Leybyuk ◽  
Mykola Rozhko ◽  
Olena Rozhko
Keyword(s):  
Diabetes Mellitus ◽  
Salivary Cortisol ◽  
Acrylic Resin ◽  
Stress Factor ◽  
Alpha Amylase ◽  
Salivary Alpha Amylase ◽  
Group I ◽  
Patients With Diabetes ◽  
Cortisol Levels ◽  
Edentulous Patients

Diabetes mellitus is referred to as non-communicable epidemic of the 21st century and the fight against diabetes is one of medical and social challenges. One of its complications is damage to periodontal tissues that is accompanied by tooth loss. Any removable denture is a foreign body being a stress factor for the oral cavity. The objective of the research was to study dynamic changes in the activity of stress factor indicators, namely salivary cortisol, glucose and alpha-amylase levels in diabetic patients after prosthodontic treatment with complete removable laminar dentures. Materials and Methods. For this study, patients at the age of 45 to 74 years were divided into two groups: Group I included 52 edentulous patients with type 2 diabetes mellitus who were treated with acrylic resin complete removable laminar dentures; Group II comprised 52 edentulous patients without endocrine pathology who were treated with acrylic resin complete removable laminar dentures as well. Saliva served as the study material. The enzyme-linked immunosorbent assay was used to determine salivary cortisol levels. Glucose concentration in saliva was determined by a unified enzymatic method. Alpha-amylase activity was determined by the enzymatic colorimetric method. Results. According to the research results, before prosthodontic treatment, salivary cortisol levels of patients with diabetes mellitus were 2.4 times higher as compared to patients without somatic pathology. In phase I of adaptation to complete removable laminar dentures, in patients with diabetes mellitus, salivary cortisol concentration increased drastically by 1.4 times as compared to the indicator before prosthodontic treatment (5.61±0.83 ng/ml vs. 4.02±0.65 ng/ml, p<0.01), while in the group of patients without endocrine pathology, cortisol levels increased by 1.2 times; salivary glucose level of patients with diabetes mellitus increased by 1.3 times, while in patients without endocrine pathology, it increased by 1.1 times; in patients of Group I, salivary alpha-amylase levels increased by 1.2 times, while in patients of Group II, salivary alpha-amylase concentration increased by 1.05 times. Conclusions. In patients with diabetes mellitus, changes in saliva composition indicate a significant reduction in the adaptation mechanisms, that complicates and significantly prolongs the period of adaptation to complete removable laminar dentures.

scholarly journals Effect of the celexoxib in microscopic changes of the esophageal mucosal of rats induced by esofagojejunostomy

2014 ◽  
Vol 41 (3) ◽  
pp. 193-197 ◽  
Author(s):  
Austry Ferreira de Lima ◽  
Laercio Gomes Lourenço ◽  
Délcio Matos ◽  
Célio Fernando de Sousa Rodrigues
Keyword(s):  
Protective Effect ◽  
Microscopic Analysis ◽  
Distal Segment ◽  
Group Iv ◽  
Esophageal Mucosa ◽  
Group Iii ◽  
Group I ◽  
Male Wistar Rats ◽  
The University ◽  
Observation Period

OBJECTIVE: To evaluate the protective effect of celecoxib in the esophageal mucosa in rats undergoing esofagojejunostomy. METHODS: Sixty male Wistar rats from the vivarium of the University of Health Sciences of Alagoas were used for the experiment. The animals were divided into four groups: Group I, 15 rats undergoing esofagojejunostomy with the use of celecoxib postoperatively; Group II, 15 rats undergoing esofagojejunostomy without the use of celecoxib; Group III, 15 rats undergoing celiotomy with bowel manipulation; and Group IV, 15 rats without surgery and using celecoxib. The observation period was 90 days. After the death of the animals, the distal segment of the esophagus was resected and sent for microscopic analysis. RESULTS: esofagojejunostomy caused macroscopic and microscopic esophagitis. Esophagitis was equal in both groups I and II. In groups III and IV esophageal lesions were not developed. CONCLUSIONS: celecoxib had neither protective nor inducing effect on esophagitis, but had a protective effect on dysplasia of the animals of group I.

scholarly journals Total staff costs to implement a decision support system in nursing

2014 ◽  
Vol 22 (1) ◽  
pp. 158-164 ◽  
Author(s):  
Valéria Castilho ◽  
Antônio Fernandes Costa Lima ◽  
Fernanda Maria Togeiro Fugulin ◽  
Heloisa Helena Ciqueto Peres ◽  
Raquel Rapone Gaidzinski
Keyword(s):  
Decision Support ◽  
Decision Support System ◽  
Support System ◽  
Sao Paulo ◽  
University Hospital ◽  
Funding Agency ◽  
São Paulo ◽  
School Of Nursing ◽  
Professional Category ◽  
The University

OBJECTIVE: to identify the direct labor (DL) costs to put in practice a decision support system (DSS) in nursing at the University Hospital of the University of São Paulo (HU-USP). METHOD: the development of the DSS was mapped in four sub-processes: Conception, Elaboration, Construction and Transition. To calculate the DL, the baseline salary per professional category was added to the five-year additional remuneration, representation fees and social charges, and then divided by the number of hours contracted, resulting in the hour wage/professional, which was multiplied by the time spend on each activity in the sub-processes. RESULTS: the DL cost corresponded to R$ 752,618.56 (100%), R$ 26,000.00 (3.45%) of which were funded by a funding agency, while R$ 726,618.56 (96,55%) came from Hospital and University resources. CONCLUSION: considering the total DL cost, 72.1% related to staff wages for the informatics consulting company and 27.9% to the DL of professionals at the HU and the School of Nursing.

Prevalence and Distribution of Diabetes Mellitus in a Maximum Care Hospital: Urgent Need for HbA1c-Screening

2017 ◽  
Vol 126 (02) ◽  
pp. 123-129 ◽  
Author(s):  
Johannes Kufeldt ◽  
Marketa Kovarova ◽  
Michael Adolph ◽  
Harald Staiger ◽  
Michael Bamberg ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Hospital Stay ◽  
Diabetes Prevalence ◽  
University Hospital ◽  
Diabetic Patients ◽  
Diabetes Diagnosis ◽  
Care Hospital ◽  
Negative Consequences ◽  
Number Needed To Screen ◽  
The University

Abstract Objective Diabetes mellitus affects almost one in 10 individuals in Germany. So far, little is known about the diabetes prevalence in maximum care hospitals. We assessed the diabetes prevalence, proportion of undiagnosed cases, the effectiveness of diabetes screening in a university hospital, the consequences for hospital stay and acquired complications. Research Design and Methods Over a 4 week period we determined HbA1c from 3 733 adult patients which were hospitalized at the university hospital of Tuebingen and had an available blood sample. Diabetes diagnosis was defined as HbA1c≥6.5% and/or previously documented diabetes diagnosis, prediabetes was defined as HbA1c≥5.7% and <6.5% without history of previous diabetes. Results 23.68% of the patients had prediabetes and 22.15% had diabetes with a high variation between the specialised departments (range 5–43%). The rate of unknown diabetes was 3.7%, the number needed to screen was 17 in patients older than 50 years. Patients with diabetes had a prolonged hospital stay compared to the mean length of stay for their diagnosis related group (diabetes: 1.47±0.24 days; no diabetes: −0.18±0.13 days, p=0.0133). The prevalence of hospital acquired complications was higher in diabetic patients (diabetes: 197 of 630; no diabetes: 447 of 2 459, p<0.0001). Conclusions Every fourth patient in the university hospital had diabetes and every second had either prediabetes or diabetes. It is also worthwhile to screen for unknown diabetes in patients over the age of 50. The high prevalence and negative consequences of diabetes require screening and intensified specialized diabetes treatment in hospitals.

scholarly journals Prevalence and outcome of gestational diabetes mellitus in women from rural population attending antenatal clinic at a teaching hospital, Tamil Nadu, India

2020 ◽  
Vol 9 (8) ◽  
pp. 3260
Author(s):  
Vidhya Muthuramalingam ◽  
Amar Nagesh Kumar
Keyword(s):  
Diabetes Mellitus ◽  
Gestational Diabetes ◽  
Gestational Diabetes Mellitus ◽  
Teaching Hospital ◽  
Tamil Nadu ◽  
Antenatal Clinic ◽  
Group Iv ◽  
Delivery Outcome ◽  
Group I ◽  
Age Range

Background: Prevalence of gestational diabetes mellitus shows wide variation across our country. From the recent studies, it is observed that incidence of gestational diabetes mellitus in antenatal women is increasing globally and India is not an exception from this. Gestational diabetes mellitus should be considered as a serious risk factor for both mother and baby as it affects two generations by having chance of developing diabetes and its related complications in future.Methods: A total of 585 pregnant women with 24 to 28 weeks of gestational age were recruited for the study. The study population was divided into four groups based on the age range; Group I include antenatal women with age <20 years, Group II includes antenatal women of age range 21-24 years, Group III includes antenatal women of age range 25-29 years, and Group IV includes antenatal women of age range ≥30 years.Results: In the present study GDM was diagnosed in 94 women among 585 antenatal women screened for GDM (16.06%). Majority of the studied population are in the age range of 20-29 years (441/585, 75.38%). The mean age of participants was 27.54±3.58 years (range 18-34 years). The prevalence of GDM was higher in the group of women aged ≥30 years (Group IV) followed by ≤20 years (Group I) (23.21% and 15.62% respectively) compared to the groups II and III (14.78% and 13.74% respectively). This observation was found to be statistically significant (p<0.001). Among 585 patients, delivery outcome was 100% successful, all delivered live babies, among them 64 patients delivered babies with macrosomia (11%).Conclusions: The study showed GDM prevalence of 16.06% from the neighboring rural villages attending our teaching hospital.

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