scholarly journals Photoluminescent Nanomaterials for Medical Biotechnology

Acta Naturae ◽  
2021 ◽  
Vol 13 (2) ◽  
pp. 16-31
Author(s):  
Evgenii L. Guryev ◽  
Samah Shanwar ◽  
Andrei Vasilevich Zvyagin ◽  
Sergey M. Deyev ◽  
Irina V. Balalaeva

Creation of various photoluminescent nanomaterials has significantly expanded the arsenal of approaches used in modern biomedicine. Their unique photophysical properties can significantly improve the sensitivity and specificity of diagnostic methods, increase therapy effectiveness, and make a theranostic approach to treatment possible through the application of nanoparticle conjugates with functional macromolecules. The most widely used nanomaterials to date are semiconductor quantum dots; gold nanoclusters; carbon dots; nanodiamonds; semiconductor porous silicon; and up-conversion nanoparticles. This paper considers the promising groups of photoluminescent nanomaterials that can be used in medical biotechnology: in particular, for devising agents for optical diagnostic methods, sensorics, and various types of therapy.

RSC Advances ◽  
2015 ◽  
Vol 5 (18) ◽  
pp. 13270-13277 ◽  
Author(s):  
Leena Mattsson ◽  
K. David Wegner ◽  
Niko Hildebrandt ◽  
Tero Soukka

The unique photophysical properties of upconverting nanoparticles (UCNPs) and semiconductor quantum dots (QDs) render them an attractive donor–acceptor combination for near-infrared (NIR) excited FRET-based optical biosensing.


2021 ◽  
Vol 42 (08) ◽  
pp. 1278-1296
Author(s):  
Dong-qi ZHANG ◽  
◽  
Jun-peng NI ◽  
Qi-tao CHEN ◽  
Yan-hong LIU ◽  
...  

2021 ◽  
Author(s):  
Qian Wang ◽  
Zhenzhen Feng ◽  
Hua He ◽  
Xiang Hu ◽  
Jian Mao ◽  
...  

Blinking occurs with nearly all fluorophores including organic dyes, fluorescent proteins, semiconductor quantum dots and carbon dots (CDs). We developed non-blinking and photoresistant fluorescent CDs by introducing multiple aromatic domains...


2012 ◽  
Vol 2012 ◽  
pp. 1-8 ◽  
Author(s):  
Jidong Wang ◽  
Shumin Han ◽  
Dandan Ke ◽  
Ruibing Wang

Semiconductor Quantum dots (QDs) have generated extensive interest for biological and clinical applications. These applications arise from their unique properties, such as high brightness, long-term stability, simultaneous detection of multiple signals, tunable emission spectra. However, high-quality QDs, whether single or core-shell QDs, are most commonly synthesized in organic solution and surface-stabilized with hydrophobic organic ligands and thus lack intrinsic aqueous solubility. For biological applications, very often it is necessary to make the QDs dispersible in water and therefore to modify the QD surfaces with various bifunctional surface ligands or caps to promote solubility in aqueous media. Well-defined methods have been developed for QD surface modification to impart biocompatibility to these systems. In this review, we summarize the recent progress and strategies of QDs surface modification for potential cancer diagnostic and therapeutic applications. In addition, the question that arose from QD surface modification, such as impact of size increase of QD bioconjugates after surface-functionalization or surface modification on photophysical properties of QDs, are also discussed.


2008 ◽  
Vol 255 (3) ◽  
pp. 691-693 ◽  
Author(s):  
P.M.A. Farias ◽  
B.S. Santos ◽  
A. Fontes ◽  
A.A.S. Vieira ◽  
D.C.N. Silva ◽  
...  

2020 ◽  
Vol 28 (15) ◽  
pp. 22705 ◽  
Author(s):  
Dmitriy Dovzhenko ◽  
Igor Martynov ◽  
Pavel Samokhvalov ◽  
Evgeniy Osipov ◽  
Maxim Lednev ◽  
...  

1999 ◽  
Vol 571 ◽  
Author(s):  
Lee K. Yeung ◽  
Kelly Sooklal ◽  
Rahina Mahtab ◽  
Bin Zhang ◽  
Richard D. Adams ◽  
...  

ABSTRACTIn the last several years, great advances have been made in the ability to synthesize semiconductor quantum dots with very narrow size distributions. Here, we report the synthesis of a series of thiolate-capped CdS quantum dots having reasonably narrow size distributions and make optical property comparisons to the crystallographically defined CdS molecular clusters having essentially “zero” size distribution. These clusters contain a “Cd10S4” core and thiolate/halide capping ligands. The luminescence of the molecular clusters, like the nanoparticles, is greatly influenced by the nature of the capping ligands. Additionally, the luminescence of the molecular clusters can be quite similar to that observed for their larger quantum dot counterparts.


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