scholarly journals Semiconductor Quantum Dots Surface Modification for Potential Cancer Diagnostic and Therapeutic Applications

2012 ◽  
Vol 2012 ◽  
pp. 1-8 ◽  
Author(s):  
Jidong Wang ◽  
Shumin Han ◽  
Dandan Ke ◽  
Ruibing Wang
Keyword(s):  
Quantum Dots ◽  
Surface Modification ◽  
Photophysical Properties ◽  
Aqueous Media ◽  
Simultaneous Detection ◽  
Emission Spectra ◽  
Semiconductor Quantum Dots ◽  
Therapeutic Applications ◽  
Cancer Diagnostic ◽  
Potential Cancer

Semiconductor Quantum dots (QDs) have generated extensive interest for biological and clinical applications. These applications arise from their unique properties, such as high brightness, long-term stability, simultaneous detection of multiple signals, tunable emission spectra. However, high-quality QDs, whether single or core-shell QDs, are most commonly synthesized in organic solution and surface-stabilized with hydrophobic organic ligands and thus lack intrinsic aqueous solubility. For biological applications, very often it is necessary to make the QDs dispersible in water and therefore to modify the QD surfaces with various bifunctional surface ligands or caps to promote solubility in aqueous media. Well-defined methods have been developed for QD surface modification to impart biocompatibility to these systems. In this review, we summarize the recent progress and strategies of QDs surface modification for potential cancer diagnostic and therapeutic applications. In addition, the question that arose from QD surface modification, such as impact of size increase of QD bioconjugates after surface-functionalization or surface modification on photophysical properties of QDs, are also discussed.

Narrow-Band Photoluminescence from Cadmium-Free I-III-VI Ternary Semiconductor Quantum Dots By Surface Modification

2020 ◽  
Vol MA2020-02 (42) ◽  
pp. 2727-2727
Author(s):  
Taro Uematsu ◽  
Kazutaka Wajima ◽  
Watcharaporn Hoisang ◽  
Dharmendar Kumar Sharma ◽  
Shuzo Hirata ◽  
...  
Keyword(s):  
Quantum Dots ◽  
Surface Modification ◽  
Narrow Band ◽  
Semiconductor Quantum Dots ◽  
Ternary Semiconductor

Upconverting nanoparticle to quantum dot FRET for homogeneous double-nano biosensors

RSC Advances ◽  
2015 ◽  
Vol 5 (18) ◽  
pp. 13270-13277 ◽  
Author(s):  
Leena Mattsson ◽  
K. David Wegner ◽  
Niko Hildebrandt ◽  
Tero Soukka
Keyword(s):  
Quantum Dots ◽  
Quantum Dot ◽  
Near Infrared ◽  
Photophysical Properties ◽  
Semiconductor Quantum Dots ◽  
Optical Biosensing ◽  
Donor Acceptor

The unique photophysical properties of upconverting nanoparticles (UCNPs) and semiconductor quantum dots (QDs) render them an attractive donor–acceptor combination for near-infrared (NIR) excited FRET-based optical biosensing.

Surface modification and functionalization of semiconductor quantum dots through reactive coating of silanes in toluene

2007 ◽  
Vol 17 (8) ◽  
pp. 800-805 ◽  
Author(s):  
Ming-Qiang Zhu ◽  
Emmanuel Chang ◽  
Jiantang Sun ◽  
Rebekah A. Drezek
Keyword(s):  
Quantum Dots ◽  
Surface Modification ◽  
Semiconductor Quantum Dots

scholarly journals Photoluminescent Nanomaterials for Medical Biotechnology

Acta Naturae ◽  
2021 ◽  
Vol 13 (2) ◽  
pp. 16-31
Author(s):  
Evgenii L. Guryev ◽  
Samah Shanwar ◽  
Andrei Vasilevich Zvyagin ◽  
Sergey M. Deyev ◽  
Irina V. Balalaeva
Keyword(s):  
Quantum Dots ◽  
Porous Silicon ◽  
Sensitivity And Specificity ◽  
Carbon Dots ◽  
Photophysical Properties ◽  
Gold Nanoclusters ◽  
Semiconductor Quantum Dots ◽  
Diagnostic Methods ◽  
Optical Diagnostic ◽  
Therapy Effectiveness

Creation of various photoluminescent nanomaterials has significantly expanded the arsenal of approaches used in modern biomedicine. Their unique photophysical properties can significantly improve the sensitivity and specificity of diagnostic methods, increase therapy effectiveness, and make a theranostic approach to treatment possible through the application of nanoparticle conjugates with functional macromolecules. The most widely used nanomaterials to date are semiconductor quantum dots; gold nanoclusters; carbon dots; nanodiamonds; semiconductor porous silicon; and up-conversion nanoparticles. This paper considers the promising groups of photoluminescent nanomaterials that can be used in medical biotechnology: in particular, for devising agents for optical diagnostic methods, sensorics, and various types of therapy.

scholarly journals The bright future: Imaging dynamic cellular events with quantum dots

2010 ◽  
Vol 32 (3) ◽  
pp. 12-17 ◽  
Author(s):  
Andrew M. Smith ◽  
Mary M. Wen ◽  
Shuming Nie
Keyword(s):  
Quantum Dots ◽  
Light Emission ◽  
Emission Spectra ◽  
Semiconductor Quantum Dots ◽  
Broad Absorption ◽  
Light Emitting ◽  
Simultaneous Excitation ◽  
New Class ◽  
Cellular Events ◽  
Optical And Electronic Properties

Semiconductor quantum dots (QDs) are tiny light-emitting particles that have emerged as a new class of fluorescent labels for biology and medicine. Compared with traditional fluorescent probes, QDs have unique optical and electronic properties such as size-tuneable light emission, narrow and symmetric emission spectra, and broad absorption spectra that enable the simultaneous excitation of multiple fluorescence colours.

Direct surface modification of semiconductor quantum dots with metal–organic frameworks

CrystEngComm ◽  
2019 ◽  
Vol 21 (37) ◽  
pp. 5568-5577 ◽  
Author(s):  
Kohei Kumagai ◽  
Taro Uematsu ◽  
Tsukasa Torimoto ◽  
Susumu Kuwabata
Keyword(s):  
Quantum Dots ◽  
Surface Modification ◽  
Metal Organic Frameworks ◽  
Semiconductor Quantum Dots ◽  
Direct Link ◽  
Metal Organic

Robust surface protective materials for luminescent semiconductor quantum dots (QDs) are demonstrated by using metal–organic frameworks (MOFs) through a direct link between them.

scholarly journals Spectrographic Microfluidic Memory

2005 ◽  
Author(s):  
David Erickson ◽  
Baiyang Li ◽  
James R. Adleman ◽  
Saurabh Vyawahare ◽  
Stephen Quake ◽  
...  
Keyword(s):  
Quantum Dots ◽  
Recent Work ◽  
Data Storage ◽  
Emission Spectra ◽  
Semiconductor Quantum Dots ◽  
Excitation Wavelength ◽  
Data Encoding ◽  
New Class ◽  
Multiple Species ◽  
Tunable Emission

Recent advancements in micro- and nanoscale fluidic manipulation have enabled the development of a new class of tunable optical structures which are collectively referred to as optofluidic devices. In this paper we will introduce our recent work directed towards the development of a spectrographic optofluidic memory. Data encoding for the memory is based on creating spectrographic codes consisting of multiple species of photoluminescent nanoparticles at discrete intensity levels which are suspended in liquids. The data cocktails are mixed, delivered and stored using a series of soft and hard-lithography microfluidic structures. Semiconductor quantum dots are ideally suited for this application due to their narrow and size tunable emission spectra and consistent excitation wavelength. Both pressure driven and electrokinetic approaches to spectral code writing have been developed and will be experimentally demonstrated here. Novel techniques for data storage and readout are also discussed and demonstrated.

A Comparison of the Photophysical Properties of Thiolate-Capped CdS Quantum Dots with Thiolate-Capped CdS Molecular Clusters

1999 ◽  
Vol 571 ◽  
Author(s):  
Lee K. Yeung ◽  
Kelly Sooklal ◽  
Rahina Mahtab ◽  
Bin Zhang ◽  
Richard D. Adams ◽  
...  
Keyword(s):  
Quantum Dots ◽  
Optical Property ◽  
Quantum Dot ◽  
Photophysical Properties ◽  
Molecular Clusters ◽  
Semiconductor Quantum Dots ◽  
Size Distributions ◽  
Cds Quantum Dots ◽  
Capping Ligands ◽  
Made In

ABSTRACTIn the last several years, great advances have been made in the ability to synthesize semiconductor quantum dots with very narrow size distributions. Here, we report the synthesis of a series of thiolate-capped CdS quantum dots having reasonably narrow size distributions and make optical property comparisons to the crystallographically defined CdS molecular clusters having essentially “zero” size distribution. These clusters contain a “Cd10S4” core and thiolate/halide capping ligands. The luminescence of the molecular clusters, like the nanoparticles, is greatly influenced by the nature of the capping ligands. Additionally, the luminescence of the molecular clusters can be quite similar to that observed for their larger quantum dot counterparts.

Sign in / Sign up

Export Citation Format

Share Document