scholarly journals Spectral Karyotyping

2020 ◽  
Author(s):  
Keyword(s):  
Spectral Karyotyping

Spectral karyotyping of Werner syndrome fibroblast cultures

2000 ◽  
Vol 91 (1-4) ◽  
pp. 180-185 ◽  
Author(s):  
R. Melcher ◽  
R. von Golitschek ◽  
C. Steinlein ◽  
D. Schindler ◽  
H. Neitzel ◽  
...  
Keyword(s):  
Werner Syndrome ◽  
Spectral Karyotyping ◽  
Fibroblast Cultures

Distinct cytogenetic pathways of advanced-stage neuroblastoma tumors, detected by spectral karyotyping

2002 ◽  
Vol 34 (3) ◽  
pp. 313-324 ◽  
Author(s):  
Batia Stark ◽  
Marta Jeison ◽  
Irit Bar-Am ◽  
Leticia Glaser-Gabay ◽  
Jacques Mardoukh ◽  
...  
Keyword(s):  
Advanced Stage ◽  
Spectral Karyotyping

scholarly journals ANALYSIS OF COMPLEX CHROMOSOMAL ABNORMALITIES IN A CASE OF MULTIPLE MYELOMA USING SPECTRAL KARYOTYPING

2018 ◽  
Vol 11 (9) ◽  
pp. 9
Author(s):  
Perumal Govindasamy ◽  
Pooja S Kulshreshtha ◽  
Prabu Pandurangan ◽  
Anil Tarigopula ◽  
Jayarama S Kadandale ◽  
...  
Keyword(s):  
Multiple Myeloma ◽  
Chromosomal Abnormalities ◽  
Bone Marrow Cells ◽  
Spectral Karyotyping ◽  
Multicolor Fish ◽  
Genetic Abnormalities ◽  
Prognostic Outcome ◽  
Conventional Cytogenetics ◽  
Marrow Cells

Objective: It was proposed to determine the chromosomal abnormalities in a 49-year-old male patient with multiple myeloma (MM) employing both conventional and advanced molecular cytogenetic techniques.Methods: GTG-banding and spectral karyotyping (SKY) on fixed metaphases obtained from LPS-stimulated bone marrow cells and interphase fluorescence in situ hybridization (iFISH) on unsorted marrow cells were carried out to identify genetic markers of prognostic significance.Results: The abnormal chromosomes observed through conventional cytogenetics could be resolved with SKY technique. The translocation t(4;14) (p16;q32) indicating FGFR3/IGH fusion and deletion of 13q14.3 was noticed using iFISH. The genetic abnormalities confirmed a poor prognostic outcome in the patient who died within 6 months of diagnosis.Conclusion: This report emphasizes the need for multicolor FISH techniques besides iFISH to resolve complex abnormalities and to identify cryptic aberrations of importance in risk stratification of MM patients.

Identification of a ring chromosome with spectral karyotyping in a pleural synovial sarcoma

2005 ◽  
Vol 160 (2) ◽  
pp. 174-178 ◽  
Author(s):  
Jun Nishio ◽  
Hiroshi Iwasaki ◽  
Pamela A. Althof ◽  
Sabine Naumann ◽  
Masako Ishiguro ◽  
...  
Keyword(s):  
Synovial Sarcoma ◽  
Ring Chromosome ◽  
Spectral Karyotyping

Multiplex FISH and Spectral Karyotyping

2009 ◽  
pp. 175-181 ◽  
Author(s):  
Thomas Liehr ◽  
Kristin Mrasek ◽  
Nadezda Kosyakova ◽  
Hasmik Mkrtchyan ◽  
Joana Melo ◽  
...  
Keyword(s):  
Spectral Karyotyping

scholarly journals Spectral Karyotyping

2003 ◽  
pp. 85-104 ◽  
Author(s):  
Jane Bayani ◽  
Jeremy A. Squire
Keyword(s):  
Spectral Karyotyping
Sign in / Sign up

Export Citation Format

Share Document