Amphetamine Sulfate

2020 ◽  
Author(s):  
Keyword(s):  
PEDIATRICS ◽  
1959 ◽  
Vol 24 (5) ◽  
pp. 761-773
Author(s):  
T. J. Egan ◽  
R. Klein

The clinical histories of three families are described, who have a variant of familial periodic paralysis characterized by high concentration of potassium during paralytic episodes unassociated with diminished urinary excretion of potassium. Data are presented concerning five hospitalized patients from the three families. The data indicate that the rise in concentration of potassium in serum results from a shift of potassium into the extracellular phase. During the recovery period potassium travels in the opposite direction. The administration of glucagon or epinephrine during an acute attack terminated the attack promptly. The administration of 10 to 15 mg of dextro-amphetamine sulfate daily in Spansule® form effectively controlled symptoms in two patients, and resulted in definite improvement in a third patient, treated for periods varying from 3 to 7 months.


1960 ◽  
Vol 7 (3) ◽  
pp. 415-433
Author(s):  
G. Y. Kenyon ◽  
N. H. Pronko
Keyword(s):  

1972 ◽  
Vol 55 (1) ◽  
pp. 146-148
Author(s):  
Clyde E Wells

Abstract Eight laboratories collaboratively studied a method for the quantitative GLC determination of d- and l-amphetamine in tablets. The drugs are separated from tablet excipients by column chromatography and reacted with Ntrifluoroacetyl-( 0-prolyl chloride, and the resulting derivatives are analyzed by GLC. The samples consisted of commercial d-amphetamine sulfate tablets (with and without butabarbital), dl-amphetamine sulfate tablets, and a mixed d- and l-amphetamine sulfate standard. Recoveries were acceptable, and the standard deviations never exceeded 0.64%. The results demonstrate that the method gives good precision and accuracy, and the method is recommended for adoption as official first action.


1970 ◽  
Vol 48 (8) ◽  
pp. 575-581 ◽  
Author(s):  
Roger Stretch ◽  
Gary J. Gerber

A system for the infusion of drug solutions into the blood stream of relatively unrestrained and unanesthetized squirrel monkeys, via a chronic intravenous catheter, is described. Results pertaining to the maintenance of schedule-controlled behavior by response-contingent infusions of d-amphetamine sulfate are included to illustrate a specific application of the technique.


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