A method for chronic intravenous drug administration in squirrel monkeys

1970 ◽  
Vol 48 (8) ◽  
pp. 575-581 ◽  
Author(s):  
Roger Stretch ◽  
Gary J. Gerber
Keyword(s):  
Drug Administration ◽  
Blood Stream ◽  
Squirrel Monkeys ◽  
Intravenous Drug ◽  
Intravenous Catheter ◽  
Response Contingent ◽  
Amphetamine Sulfate

A system for the infusion of drug solutions into the blood stream of relatively unrestrained and unanesthetized squirrel monkeys, via a chronic intravenous catheter, is described. Results pertaining to the maintenance of schedule-controlled behavior by response-contingent infusions of d-amphetamine sulfate are included to illustrate a specific application of the technique.

The Pharmacology of Verapamil. III. Pharmacokinetics in Normal Subjects After Intravenous Drug Administration

1981 ◽  
Vol 3 (1) ◽  
pp. 25-38 ◽  
Author(s):  
Jerome A. Dominic ◽  
David W. A. Bourne ◽  
Tiong G. Tan ◽  
Edward B. Kirsten ◽  
R. G. McAllister
Keyword(s):  
Drug Administration ◽  
Normal Subjects ◽  
Intravenous Drug

scholarly journals Brief Report on Double-Chamber Syringes Patents and Implications for Infusion Therapy Safety and Efficiency

2020 ◽  
Vol 17 (21) ◽  
pp. 8209 ◽  
Author(s):  
Liliana B. Sousa ◽  
Paulo Santos-Costa ◽  
Inês A. Marques ◽  
Arménio Cruz ◽  
Anabela Salgueiro-Oliveira ◽  
...  
Keyword(s):  
Drug Administration ◽  
Data Extraction ◽  
Intravenous Drug ◽  
Standards Of Care ◽  
Infusion Therapy ◽  
Search Terms ◽  
Freeze Dried ◽  
Injection Safety ◽  
Current Standards ◽  
Double Chamber

This review aimed to map the existing patents of double-chamber syringes that can be used for intravenous drug administration and catheter flush. A search was conducted in the Google patents database for records published prior to 28 October 2020, using several search terms related to double-chamber syringes (DCS). Study eligibility and data extraction were performed by two independent reviewers. Of the initial 26,110 patents found, 24 were included in this review. The 24 DCS that were found display two or more independent chambers that allow for the administration of multiple solutions. While some of the DCS have designated one of the chambers as the flushing chamber, most patents only allow for the sequential use of the flushing chamber after intravenous drug administration. Most DCS were developed for drug reconstitution, usually with a freeze-dried drug in one chamber. Some patents were designed for safety purposes, with a parallel post-injection safety sheath chamber for enclosing a sharpened needle tip. None of the DCS found allow for a pre- and post-intravenous drug administration flush. Given the current standards of care in infusion therapy, future devices must allow for the sequential use of the flushing chamber to promote a pre-administration patency assessment and a post-administration device flush.

scholarly journals Optimizing intravenous drug administration by applying pharmacokinetic/pharmacodynamic concepts

2011 ◽  
Vol 107 (1) ◽  
pp. 38-47 ◽  
Author(s):  
M.M.R.F. Struys ◽  
M. Sahinovic ◽  
B.J. Lichtenbelt ◽  
H.E.M. Vereecke ◽  
A.R. Absalom
Keyword(s):  
Drug Administration ◽  
Intravenous Drug

Calculating Drug Infusion Rates

2017 ◽  
Vol 27 (1-2) ◽  
pp. 25-27
Author(s):  
J England
Keyword(s):  
General Anaesthesia ◽  
Drug Administration ◽  
Intravenous Drug ◽  
Toxic Effects ◽  
Therapeutic Effects ◽  
Drug Infusion

Intravenous drug administration is necessary for most patients who undergo general anaesthesia, and calculating correct dosages is essential, if those patients are to benefit from the proper therapeutic effects from their administered drugs, rather than suffering from any toxic effects which might result from overdosing.

Disinfection practices in intravenous drug administration

2016 ◽  
Vol 44 (6) ◽  
pp. 721-723 ◽  
Author(s):  
Onno K. Helder ◽  
René F. Kornelisse ◽  
Irwin K.M. Reiss ◽  
Erwin Ista
Keyword(s):  
Drug Administration ◽  
Intravenous Drug
Sign in / Sign up

Export Citation Format

Share Document