Substance Withdrawal Delirium

Management of alcohol withdrawal and other selected substance withdrawal issues

Psychosomatic Medicine ◽

10.1017/cbo9780511776878.022 ◽

2010 ◽

pp. 193-201 ◽

Cited By ~ 1

Author(s):

Philip A. Bialer ◽

Anthony C. Miller

Keyword(s):

Alcohol Withdrawal ◽

Substance Withdrawal

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COVID‐19 encephalopathy masquerading as substance withdrawal

Journal of Medical Virology ◽

10.1002/jmv.26065 ◽

2020 ◽

Vol 92 (11) ◽

pp. 2376-2378 ◽

Cited By ~ 1

Author(s):

Sean Byrnes ◽

Maneesh Bisen ◽

Baseer Syed ◽

Syed Huda ◽

Zaid Siddique ◽

...

Keyword(s):

Substance Withdrawal

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Development of a Clinical Competency Checklist for Care of Patients Experiencing Substance Withdrawal Delirium or Delirium: Use of a Delphi Technique and Expert Panel

Journal of Psychosocial Nursing and Mental Health Services ◽

10.3928/02793695-20150526-01 ◽

2015 ◽

Vol 53 (6) ◽

pp. 29-36 ◽

Cited By ~ 2

Author(s):

Jennifer L. Saylor ◽

Kathleen A. Schell ◽

Mark F. Mendell ◽

Jennifer S. Graber

Keyword(s):

Delphi Technique ◽

Expert Panel ◽

Clinical Competency ◽

Substance Withdrawal

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Delirium and Substance Withdrawal

Acute Care of the Cancer Patient ◽

10.1201/b14119-35 ◽

2005 ◽

pp. 545-557

Author(s):

Alan Valentine ◽

Jacqueline Bickham

Keyword(s):

Substance Withdrawal

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Substance Withdrawal in ICU Environment

Oncologic Critical Care ◽

10.1007/978-3-319-74698-2_143-1 ◽

2019 ◽

pp. 1-21

Author(s):

Nuria Martínez ◽

María-Consuelo Pintado

Keyword(s):

Substance Withdrawal

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Pharmacological Treatments of Non-Substance-Withdrawal Delirium: A Systematic Review of Prospective Trials

American Journal of Psychiatry ◽

10.1176/appi.ajp.2013.13040458 ◽

2014 ◽

Vol 171 (2) ◽

pp. 151-159 ◽

Cited By ~ 41

Author(s):

Joseph I. Friedman ◽

Laili Soleimani ◽

Daniel P. McGonigle ◽

Claudine Egol ◽

Jeffrey H. Silverstein

Keyword(s):

Systematic Review ◽

Pharmacological Treatments ◽

Prospective Trials ◽

Substance Withdrawal

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Delirium in the course of dependence upon gamma-butyrolactone (GBL) - a case report

Current Problems of Psychiatry ◽

10.1515/cpp-2016-0029 ◽

2016 ◽

Vol 17 (4) ◽

pp. 297-302

Author(s):

Łukasz Łobejko ◽

Piotr Machała ◽

Agata Makarewicz ◽

Hanna Karakuła Juchnowicz

Keyword(s):

Physical Dependence ◽

Easy Access ◽

Organic Chemical ◽

Psychiatric Ward ◽

Gamma Hydroxybutyrate ◽

Life Threatening ◽

Withdrawal Syndromes ◽

Substance Withdrawal ◽

Dose Dependent ◽

Gamma Butyrolactone

AbstractGamma-butyrolactone (GBL) is an organic chemical compound of the lactones group, undergoing biotransformation into gamma-hydroxybutyrate after the intake (GHB). Because of the easy access, low price and fast psychotropic effect, GBL is becoming increasingly popular substance having intoxicating effect. Taking of GBL causes dose-dependent euphoric, sedative, hypnotic effects. Its use can quickly lead to physical dependence with severe course of withdrawal syndromes. Withdrawal symptoms resemble those occurring in the course of addiction to alcohol or benzodiazepines. In some patients, delirium develops during substance withdrawal. There are described severe, life-threatening complications in the course of delirium in GBL-dependent patients. The management of withdrawal syndromes and delirium mainly involves administration of benzodiazepines. In this paper, we present a case of delirium in 24-year-old man addicted to GBL hospitalized in a psychiatric ward. Delirium in this patient went without complications and was successfully managed with diazepam and lorazepam.

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Sleep disturbances, psychiatric disorders, and psychotropic drugs

Dialogues in Clinical Neuroscience ◽

10.31887/dcns.2005.7.4/lstaner ◽

2005 ◽

Vol 7 (4) ◽

pp. 323-334

Keyword(s):

Psychiatric Disorders ◽

Psychotropic Drugs ◽

Sleep Disturbances ◽

Neural Mechanisms ◽

Brain Functioning ◽

Pathophysiological Process ◽

Corrective Effect ◽

Brain Neurotransmitter ◽

Substance Withdrawal ◽

The Relationship

Brain neurotransmitter dysfunctions involved in the pathophysiological processes of psychiatric disorders are likely to be reflected by concomitant alterations in sleep continuity and architecture. Since the corrective effects of psychotropic drugs on dysfunctional neurotransmission systems can be evidenced through polysomnographic recordings, one may consider sleep as a kind of "window" on the neurobiology of psychiatric disorders. During the last 10 years, major breakthroughs in our understanding of sleep-wake mechanisms have provided some indications on how psychotropic drugs could influence the sleep-wake cycle. In this review, recent inroads into the understanding of sleep regulatory neural mechanisms are introduced and discussed in terms of the effects of psychotropic drugs. The relationship between the pathophysiological process of a disease, its consequence on sleep, and the corrective effect of a psychotropic drug are exemplified by two psychopathological states: substance withdrawal and major depression. One may conclude that polysomnographic recordings are a unique noninvasive tool to analyze brain functioning, and are particularly well suited to evaluating the objective effects of new psychotropic drugs.

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