scholarly journals Uterine Corpus Smooth Muscle Neoplasm

2020 ◽  
Author(s):  
2021 ◽  
pp. 106689692199779
Author(s):  
Murat Celik

Leiomyoma is a benign mesenchymal tumor that develops from smooth muscle cells. It can present in various histological variants. Leiomyoma with bizarre nuclei is an infrequent variant of uterine smooth muscle neoplasm. It is characterized by focally or diffusely distributed bizarre cells on the background of a typical leiomyoma. These bizarre cells are large, multinucleated, or multilobulated and have an eosinophilic cytoplasm. Even though leiomyomas with bizarre nuclei display benign clinical behavior, their differential diagnosis from leiomyosarcoma can sometimes be difficult. Leiomyoma has been described most commonly in the uterus. There is no case of leiomyoma originating from paratubal cysts described in the literature. In this article, we present a rare case of leiomyoma with bizarre nuclei originating from a paratubal cyst.


2004 ◽  
Vol 128 (12) ◽  
pp. 1442-1444 ◽  
Author(s):  
Katherine M. Ceballos ◽  
Julie-Ann Francis ◽  
John L. Mazurka

Abstract Gastrointestinal stromal tumors are CD117 (c-Kit)–positive mesenchymal neoplasms with histologic and ultrastructural features of the interstitial cell of Cajal. While tumors outside of the gastrointestinal tract have been described, to our knowledge the case we present is the first such case in the vagina. We describe a 75-year-old woman with a recurrent vaginal gastrointestinal stromal tumor without apparent rectal involvement. This tumor was characterized by short intersecting fascicles of spindled cells, focal necrosis, and 12 to 15 mitoses per 50 high-power fields. Immunohistochemistry revealed diffuse cytoplasmic positivity for CD117 (c-Kit), CD34, vimentin, and h-caldesmon. Tumor cells were negative for S100, desmin, actin, and CAM 5.2. The differential diagnosis in this case included a vaginal smooth muscle tumor. While histologically similar to a smooth muscle neoplasm, the immunohistochemical profile ruled out smooth muscle differentiation. Gastrointestinal stromal tumor should be considered in the differential diagnosis of vaginal mesenchymal neoplasms.


CHEST Journal ◽  
1983 ◽  
Vol 83 (2) ◽  
pp. 270-274 ◽  
Author(s):  
Guillermo A. Herrera ◽  
Philip A. Miles ◽  
Harvey Greenberg ◽  
Bernhard E.F. Reimann ◽  
Idelle M. Weisman

1998 ◽  
Vol 37 (2) ◽  
pp. 205-208
Author(s):  
Xuefeng Jing ◽  
Yasushi Nakamura ◽  
Misa Nakamura ◽  
Liang Shan ◽  
Toyoharu Yokoi ◽  
...  

Medicine ◽  
2018 ◽  
Vol 97 (46) ◽  
pp. e13250
Author(s):  
Genki Usui ◽  
Hirotsugu Hashimoto ◽  
Kazuteru Watanabe ◽  
Yoshiya Sugiura ◽  
Masashi Kusakabe ◽  
...  

1995 ◽  
Vol 177 (1) ◽  
pp. 65-70 ◽  
Author(s):  
Michael D. Jeffers ◽  
Maura A. Farquharson ◽  
James A. Richmond ◽  
Ann Marie McNicol

2013 ◽  
Vol 40 (6) ◽  
pp. 557-563 ◽  
Author(s):  
Munir H Idriss ◽  
Viktoryia Kazlouskaya ◽  
Saurabh Malhotra ◽  
Christian Andres ◽  
Dirk M. Elston

2015 ◽  
Vol 68 (6) ◽  
pp. 418-426 ◽  
Author(s):  
Niamh Conlon ◽  
Robert A Soslow ◽  
Rajmohan Murali

Perivascular epithelioid tumours (PEComas) of the gynaecological tract are rare tumours which were first recognised and diagnosed within the last 20 years. They represent a unique diagnostic challenge with regard to their accurate and reproducible distinction from more common entities such as smooth muscle tumours of the uterine corpus. In this review article, we trace the development of the concept of the PEComa tumour family, highlight what is known about extra-gynaecological tract PEComa at an immunohistochemical, molecular and therapeutic level and then present a summary of all reported cases of gynaecological tract PEComa to date. In the summary, we highlight rare subtypes of gynaecological tract PEComa and compare the performances of extant prognostic classification systems for malignancy in these tumours.


2006 ◽  
Vol 19 (6) ◽  
pp. 835.e1-835.e3 ◽  
Author(s):  
Steven C. Horton ◽  
Stephanie Nay ◽  
Michael Gonzales ◽  
Marsha McIntosh ◽  
Elizabeth Hammond ◽  
...  

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