scholarly journals A novel approach to early sickness absence management: The EASY (Early Access to Support for You) way

Work ◽  
2016 ◽  
Vol 53 (3) ◽  
pp. 597-608 ◽  
Author(s):  
Evangelia Demou ◽  
Judith Brown ◽  
Kaveh Sanati ◽  
Mark Kennedy ◽  
Keith Murray ◽  
...  
Keyword(s):  
Sickness Absence ◽  
Early Access ◽  
Novel Approach ◽  
Absence Management

scholarly journals The EASY (Early Access to Support for You) sickness absence service: a four-year evaluation of the impact on absenteeism

2015 ◽  
Vol 41 (2) ◽  
pp. 204-215 ◽  
Author(s):  
Judith Brown ◽  
Daniel Mackay ◽  
Evangelia Demou ◽  
Joyce Craig ◽  
John Frank ◽  
...  
Keyword(s):  
Sickness Absence ◽  
Early Access ◽  
The Impact

Wincanton reduces sickness absence by 10,000 days

2009 ◽  
Vol 17 (1) ◽  
pp. 35-37
Author(s):  
Carol Madden
Keyword(s):  
Sickness Absence ◽  
Positive Impact ◽  
Good Practice ◽  
Cost Savings ◽  
Management Program ◽  
Management Service ◽  
Staff Morale ◽  
Content Type ◽  
Active Approach ◽  
Absence Management

PurposeThis paper aims to demonstrate how supply‐chain company Wincanton has reduced sickness absence, improved productivity and heightened morale.Design/methodology/approachDraws upon the experience of Wincanton's sickness absence management program, driven by the partnership between the HR department, Wincanton employees and absence‐management specialist active health partners (AHP).FindingsDescribes the significant variation in staff‐absence levels across different sites and types of work contract and the detrimental effects of such absence on Wincanton's performance. The company selected an absence‐management service led by nurses in order to provide effective, timely medical advice, encouraging staff to take responsibility for their health while at the same time facilitating a prompt return to work.Practical implicationsShows how taking an active approach to staff absence and aligning reporting systems to identify and share good practice have had a positive impact on staff morale, productivity and profitability.Originality/valueHighlights a significant reduction in average absence figures per employee and cost savings for the business.

Managing and avoiding sickness absence

2013 ◽  
pp. 585-607 ◽  
Author(s):  
Richard Preece ◽  
Dean Royles
Keyword(s):  
Occupational Health ◽  
Health Services ◽  
Sickness Absence ◽  
Health Problems ◽  
Occupational Health Services ◽  
Major Activity ◽  
Fitness To Work ◽  
Absence Management

Sickness absence is an important issue for workers, managers, and occupational health services. Most employees suffer health problems at some time during their career and face decisions on fitness in relation to their work. All employers will occasionally be concerned about the fitness to work of absent employees and what actions they might take to address this. Advising on sickness absence management and the fitness to work of absentees, individually and collectively, is a major activity for occupational health specialists.

Copper-dependent ATP7B up-regulation drives the resistance of TMEM16A-overexpressing head-and-neck cancer models to platinum toxicity

2019 ◽  
Vol 476 (24) ◽  
pp. 3705-3719 ◽  
Author(s):  
Avani Vyas ◽  
Umamaheswar Duvvuri ◽  
Kirill Kiselyov
Keyword(s):  
Oxidative Stress ◽  
Head And Neck ◽  
Transcriptional Activation ◽  
Platinum Resistance ◽  
Mrna Levels ◽  
Strong Positive Correlation ◽  
Platinum Compounds ◽  
Copper Chelation ◽  
Novel Approach ◽  
Cancer Models

Platinum-containing drugs such as cisplatin and carboplatin are routinely used for the treatment of many solid tumors including squamous cell carcinoma of the head and neck (SCCHN). However, SCCHN resistance to platinum compounds is well documented. The resistance to platinum has been linked to the activity of divalent transporter ATP7B, which pumps platinum from the cytoplasm into lysosomes, decreasing its concentration in the cytoplasm. Several cancer models show increased expression of ATP7B; however, the reason for such an increase is not known. Here we show a strong positive correlation between mRNA levels of TMEM16A and ATP7B in human SCCHN tumors. TMEM16A overexpression and depletion in SCCHN cell lines caused parallel changes in the ATP7B mRNA levels. The ATP7B increase in TMEM16A-overexpressing cells was reversed by suppression of NADPH oxidase 2 (NOX2), by the antioxidant N-Acetyl-Cysteine (NAC) and by copper chelation using cuprizone and bathocuproine sulphonate (BCS). Pretreatment with either chelator significantly increased cisplatin's sensitivity, particularly in the context of TMEM16A overexpression. We propose that increased oxidative stress in TMEM16A-overexpressing cells liberates the chelated copper in the cytoplasm, leading to the transcriptional activation of ATP7B expression. This, in turn, decreases the efficacy of platinum compounds by promoting their vesicular sequestration. We think that such a new explanation of the mechanism of SCCHN tumors’ platinum resistance identifies novel approach to treating these tumors.

Collecting Words: A Clinical Example of a Morphology-Focused Orthographic Intervention

2020 ◽  
Vol 51 (3) ◽  
pp. 544-560 ◽  
Author(s):  
Kimberly A. Murphy ◽  
Emily A. Diehm
Keyword(s):  
Written Language ◽  
Morphological Knowledge ◽  
English Orthography ◽  
Word Level ◽  
Novel Approach ◽  
Language Pathology ◽  
The One ◽  
Critical Intervention ◽  
Reading And Spelling ◽  
Reading And Spelling Difficulties

Purpose Morphological interventions promote gains in morphological knowledge and in other oral and written language skills (e.g., phonological awareness, vocabulary, reading, and spelling), yet we have a limited understanding of critical intervention features. In this clinical focus article, we describe a relatively novel approach to teaching morphology that considers its role as the key organizing principle of English orthography. We also present a clinical example of such an intervention delivered during a summer camp at a university speech and hearing clinic. Method Graduate speech-language pathology students provided a 6-week morphology-focused orthographic intervention to children in first through fourth grade ( n = 10) who demonstrated word-level reading and spelling difficulties. The intervention focused children's attention on morphological families, teaching how morphology is interrelated with phonology and etymology in English orthography. Results Comparing pre- and posttest scores, children demonstrated improvement in reading and/or spelling abilities, with the largest gains observed in spelling affixes within polymorphemic words. Children and their caregivers reacted positively to the intervention. Therefore, data from the camp offer preliminary support for teaching morphology within the context of written words, and the intervention appears to be a feasible approach for simultaneously increasing morphological knowledge, reading, and spelling. Conclusion Children with word-level reading and spelling difficulties may benefit from a morphology-focused orthographic intervention, such as the one described here. Research on the approach is warranted, and clinicians are encouraged to explore its possible effectiveness in their practice. Supplemental Material https://doi.org/10.23641/asha.12290687

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