Wild Andean blackberry (Rubus glaucus Benth) and Andean blueberry (Vaccinium floribundum Kunth) from the Highlands of Ecuador: Nutritional composition and protective effect on human dermal fibroblasts against cytotoxic oxidative damage

2018 ◽  
Vol 8 (3) ◽  
pp. 223-236 ◽  
Author(s):  
Karina S. Alarcón-Barrera ◽  
Daniela S. Armijos-Montesinos ◽  
Marilyn García-Tenesaca ◽  
Gabriel Iturralde ◽  
Tatiana Jaramilo-Vivanco ◽  
...  
Keyword(s):  
Oxidative Damage ◽  
Protective Effect ◽  
Nutritional Composition ◽  
Dermal Fibroblasts ◽  
Human Dermal Fibroblasts

scholarly journals The protective effect of acerola (Malpighia emarginata) against oxidative damage in human dermal fibroblasts through the improvement of antioxidant enzyme activity and mitochondrial functionality

2017 ◽  
Vol 8 (9) ◽  
pp. 3250-3258 ◽  
Author(s):  
José M. Alvarez-Suarez ◽  
Francesca Giampieri ◽  
Massimiliano Gasparrini ◽  
Luca Mazzoni ◽  
Celestino Santos-Buelga ◽  
...  
Keyword(s):  
Enzyme Activity ◽  
Oxidative Damage ◽  
Protective Effect ◽  
Antioxidant Enzyme ◽  
Bioactive Compounds ◽  
Antioxidant Enzyme Activity ◽  
Dermal Fibroblasts ◽  
Natural Source ◽  
Human Dermal Fibroblasts ◽  
Malpighia Emarginata

Acerola fruits are shown as an important natural source of bioactive compounds with beneficial properties for health.

scholarly journals Protective Effect of Sulfated Polysaccharides from Celluclast-Assisted Extract of Hizikia fusiforme Against Ultraviolet B-Induced Skin Damage by Regulating NF-κB, AP-1, and MAPKs Signaling Pathways In Vitro in Human Dermal Fibroblasts

Marine Drugs ◽  
2018 ◽  
Vol 16 (7) ◽  
pp. 239 ◽  
Author(s):  
Lei Wang ◽  
WonWoo Lee ◽  
Jae Oh ◽  
Yong Cui ◽  
BoMi Ryu ◽  
...  
Keyword(s):  
Protective Effect ◽  
Signaling Pathways ◽  
Dermal Fibroblasts ◽  
Sulfated Polysaccharides ◽  
Dependent Manner ◽  
Human Dermal Fibroblasts ◽  
Skin Damage ◽  
Hizikia Fusiforme ◽  
Hdf Cells

Our previous study evaluated the antioxidant activities of sulfated polysaccharides from Celluclast-assisted extract of Hizikia fusiforme (HFPS) in vitro in Vero cells and in vivo in zebrafish. The results showed that HFPS possesses strong antioxidant activity and suggested the potential photo-protective activities of HFPS. Hence, in the present study, we investigated the protective effects of HFPS against ultraviolet (UV) B-induced skin damage in vitro in human dermal fibroblasts (HDF cells). The results indicate that HFPS significantly reduced intracellular reactive oxygen species (ROS) level and improved the viability of UVB-irradiated HDF cells in a dose-dependent manner. Furthermore, HFPS significantly inhibited intracellular collagenase and elastase activities, remarkably protected collagen synthesis, and reduced matrix metalloproteinases (MMPs) expression by regulating nuclear factor kappa B (NF-κB), activator protein 1 (AP-1), and mitogen-activated protein kinases (MAPKs) signaling pathways in UVB-irradiated HDF cells. These results suggest that HFPS possesses strong UV protective effect, and can be a potential ingredient in the pharmaceutical and cosmetic industries.

scholarly journals Prevention of UVA-Induced Oxidative Damage in Human Dermal Fibroblasts by New UV Filters, Assessed Using a Novel In Vitro Experimental System

PLoS ONE ◽  
2014 ◽  
Vol 9 (1) ◽  
pp. e83401 ◽  
Author(s):  
Francesca Brugè ◽  
Luca Tiano ◽  
Paola Astolfi ◽  
Monica Emanuelli ◽  
Elisabetta Damiani
Keyword(s):  
Oxidative Damage ◽  
Experimental System ◽  
Dermal Fibroblasts ◽  
Human Dermal Fibroblasts ◽  
Uv Filters

scholarly journals Protective Effect of Strawberry Extract against Inflammatory Stress Induced in Human Dermal Fibroblasts

Molecules ◽  
2017 ◽  
Vol 22 (1) ◽  
pp. 164 ◽  
Author(s):  
Massimiliano Gasparrini ◽  
Tamara Forbes-Hernandez ◽  
Francesca Giampieri ◽  
Sadia Afrin ◽  
Bruno Mezzetti ◽  
...  
Keyword(s):  
Protective Effect ◽  
Dermal Fibroblasts ◽  
Human Dermal Fibroblasts ◽  
Inflammatory Stress
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