scholarly journals The protective effect of acerola (Malpighia emarginata) against oxidative damage in human dermal fibroblasts through the improvement of antioxidant enzyme activity and mitochondrial functionality

2017 ◽  
Vol 8 (9) ◽  
pp. 3250-3258 ◽  
Author(s):  
José M. Alvarez-Suarez ◽  
Francesca Giampieri ◽  
Massimiliano Gasparrini ◽  
Luca Mazzoni ◽  
Celestino Santos-Buelga ◽  
...  
Keyword(s):  
Enzyme Activity ◽  
Oxidative Damage ◽  
Protective Effect ◽  
Antioxidant Enzyme ◽  
Bioactive Compounds ◽  
Antioxidant Enzyme Activity ◽  
Dermal Fibroblasts ◽  
Natural Source ◽  
Human Dermal Fibroblasts ◽  
Malpighia Emarginata

Acerola fruits are shown as an important natural source of bioactive compounds with beneficial properties for health.

Effect of Oxidative Stress on Lymphocytes from Elderly Subjects

1998 ◽  
Vol 94 (4) ◽  
pp. 447-452 ◽  
Author(s):  
E. García-Arumí ◽  
A. L. Andreu ◽  
J. López-Hellín ◽  
S. Schwartz
Keyword(s):  
Oxidative Stress ◽  
Enzyme Activity ◽  
Oxidative Damage ◽  
Antioxidant Enzyme ◽  
Antioxidant Enzyme Activity ◽  
Elderly Subjects ◽  
Antioxidant Enzyme Activities ◽  
Antioxidant Defences ◽  
Protein Carbonyl Content ◽  
Healthy Elderly

1. Oxidative damage has been associated with ageing, but there is no agreement as to whether or not it is produced by a decrease in antioxidant defences with the ageing process. In purified lymphocytes from 47 healthy elderly (75.27 ± 0.91 years) and 47 healthy young (29.87 ± 0.53 years) volunteers, we studied the levels of antioxidant enzyme activity (superoxide dismutase, catalase and glutathione peroxidase), protein oxidative damage (as protein carbonyl content) and lysosomal proteolytic activity (cathepsins B, H and L), with and without exposure to oxidative stress produced by 25 μmol/l H2O2. 2. There were no differences in antioxidant enzyme activities in the stressed and non-stressed samples between the young and elderly subjects, indicating that there was no relationship between age and antioxidant enzyme activity even in oxidative stress. However, a dissimilar response to oxidative stress was observed in protein oxidative damage and cathepsin B and L activities, depending on the age of the donor. 3. With these results we conclude that oxidative stress produces greater protein oxidative damage and increased protein degradation in elderly subjects than in young ones; this effect cannot be attributed to dissimilar antioxidant enzyme responses to oxidative stress, since these did not differ between the two age groups.

Novel phenolic glucoside, origanoside, protects against oxidative damage and modulates antioxidant enzyme activity

2011 ◽  
Vol 44 (5) ◽  
pp. 1496-1503 ◽  
Author(s):  
Tzung-Han Chou ◽  
Hsiou-Yu Ding ◽  
Leong-Perng Chan ◽  
Jing-Yao Liang ◽  
Chia-Hua Liang
Keyword(s):  
Enzyme Activity ◽  
Oxidative Damage ◽  
Antioxidant Enzyme ◽  
Antioxidant Enzyme Activity ◽  
Phenolic Glucoside

Napiergrass (Pennisetum purpureum S.) protects oxidative damage of biomolecules and modulates antioxidant enzyme activity

2007 ◽  
Vol 105 (4) ◽  
pp. 1364-1374 ◽  
Author(s):  
Hui Mei Yu ◽  
Bor-Sen Wang ◽  
Heuy Ling Chu ◽  
Lee-Wen Chang ◽  
Wen-Jye Yen ◽  
...  
Keyword(s):  
Enzyme Activity ◽  
Oxidative Damage ◽  
Antioxidant Enzyme ◽  
Antioxidant Enzyme Activity ◽  
Pennisetum Purpureum

scholarly journals Effect of drought stress on oxidative damage and antioxidant enzyme activity in melon seedlings

2013 ◽  
Vol 37 ◽  
pp. 491-498 ◽  
Author(s):  
Musa KAVAS ◽  
Mehmet Cengiz BALOĞLU ◽  
Oya AKÇA ◽  
Fatma Selin KÖSE ◽  
Derya GÖKÇAY
Keyword(s):  
Enzyme Activity ◽  
Drought Stress ◽  
Oxidative Damage ◽  
Antioxidant Enzyme ◽  
Antioxidant Enzyme Activity

Antioxidant Enzyme Levels Inversely Covary with Hearing Loss After Amikacin Treatment

2003 ◽  
Vol 14 (03) ◽  
pp. 134-143 ◽  
Author(s):  
James J. Klemens ◽  
Robert P. Meech ◽  
Larry F. Hughes ◽  
Satu Somani ◽  
Kathleen C.M. Campbell
Keyword(s):  
Hearing Loss ◽  
Enzyme Activity ◽  
Antioxidant Enzyme ◽  
Guinea Pigs ◽  
Auditory Brainstem ◽  
Antioxidant Enzyme Activity ◽  
Control Group ◽  
Glutathione S Transferase ◽  
Brainstem Response ◽  
The Difference

This study's purpose was to determine if a correlation exists between cochlear antioxidant activity changes and auditory function after induction of aminoglycoside (AG) ototoxicity. Two groups of five 250-350 g albino guinea pigs served as subjects. For 28 days, albino guinea pigs were administered either 200 mg/kg/day amikacin, or saline subcutaneously. Auditory brainstem response testing was performed prior to the first injection and again before sacrifice, 28 days later. Cochleae were harvested and superoxide dismutase, catalase, glutathione peroxidase, glutathione-S-transferase, glutathione reductase activities and malondialdehyde levels were measured. All antioxidant enzymes had significantly lower activity in the amikacin group (p ≤ 0.05) than in the control group. The difference in cochlear antioxidant enzyme activity between groups inversely correlated significantly with the change in ABR thresholds. The greatest correlation was for the high frequencies, which are most affected by aminoglycosides. This study demonstrates that antioxidant enzyme activity and amikacin-induced hearing loss significantly covary.

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