Evaluation of integrated color-coded perfusion analysis for contrast-enhanced ultrasound (CEUS) after percutaneous interventions for malignant liver lesions: First results

2018 ◽  
Vol 69 (1-2) ◽  
pp. 59-67 ◽  
Author(s):  
I. Wiesinger ◽  
L.P. Beyer ◽  
N. Zausig ◽  
N. Verloh ◽  
P. Wiggermann ◽  
...  
Keyword(s):  
Liver Lesions ◽  
Contrast Enhanced Ultrasound ◽  
Percutaneous Interventions ◽  
Contrast Enhanced ◽  
First Results ◽  
Malignant Liver ◽  
Malignant Liver Lesions

Contrast-enhanced ultrasound of malignant liver lesions

2017 ◽  
Vol 43 (4) ◽  
pp. 819-847 ◽  
Author(s):  
Isabelle Durot ◽  
Stephanie R. Wilson ◽  
Jürgen K. Willmann
Keyword(s):  
Liver Lesions ◽  
Contrast Enhanced Ultrasound ◽  
Contrast Enhanced ◽  
Malignant Liver ◽  
Malignant Liver Lesions

Characterizing malignant liver lesions with contrast-enhanced ultrasound

2014 ◽  
Vol 75 (3) ◽  
pp. 151-154 ◽  
Author(s):  
Mark Wills ◽  
Chris J Harvey ◽  
Siarhei Kuzmich ◽  
Asim Afaq ◽  
Adrian Lim ◽  
...  
Keyword(s):  
Liver Lesions ◽  
Contrast Enhanced Ultrasound ◽  
Contrast Enhanced ◽  
Malignant Liver ◽  
Malignant Liver Lesions

scholarly journals Triple-Phase Multidetector Computed Tomography in Distinguishing Canine Hepatic Lesions

Animals ◽  
2020 ◽  
Vol 11 (1) ◽  
pp. 11
Author(s):  
Ladislav Stehlík ◽  
Morena Di Tommaso ◽  
Francesca Del Signore ◽  
Michaela Paninárová ◽  
Rossella Terragni ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Phase Contrast ◽  
Normal Liver ◽  
Liver Parenchyma ◽  
Liver Lesions ◽  
Contrast Enhanced ◽  
Malignant Liver ◽  
Enhanced Computed Tomography ◽  
Contrast Enhanced Computed Tomography ◽  
Malignant Liver Lesions

The liver has a unique vascular supply, and triple-phase contrast-enhanced computed tomography examinations are being performed in order to characterize liver lesions. This study aimed to look for any associations between the attenuation values of liver lesions and their histological classification. The inclusion criteria for this retrospective study were focal or multifocal liver lesions and histological diagnosis. All of the dogs underwent pre-contrast and triple-phase postcontrast computed tomography (CT) examinations with identical timings of the postcontrast series. Thirty-one dogs were included in the study, and various benign and malignant pathologies were identified. The results did not identify any significant differences between the benign and malignant liver lesions, nor between the individual histological diagnoses. Inflammatory lesions were significantly different compared to the normal liver parenchyma, and significant hypoattenuation was found in the portal and delayed venous phases. Hemangiosarcomas were significantly hypoattenuating to the normal liver parenchyma in the pre-contrast and arterial phases, and also to all of the benign lesions in the arterial phase. The other pathologies showed variable attenuation patterns in the different postcontrast phases, and differentiation was not possible. On the basis of this study, triple-phase contrast-enhanced computed tomography cannot differentiate between benign and malignant liver lesions, and biopsy and further histological analysis are necessary.

scholarly journals Volume Navigation with Contrast Enhanced Ultrasound and Image Fusion for Percutaneous Interventions: First Results

PLoS ONE ◽  
2012 ◽  
Vol 7 (3) ◽  
pp. e33956 ◽  
Author(s):  
Ernst Michael Jung ◽  
Chris Friedrich ◽  
Patrick Hoffstetter ◽  
Lena Marie Dendl ◽  
Frank Klebl ◽  
...  
Keyword(s):  
Image Fusion ◽  
Contrast Enhanced Ultrasound ◽  
Percutaneous Interventions ◽  
Contrast Enhanced ◽  
First Results

scholarly journals Color Coded Perfusion Imaging with Contrast Enhanced Ultrasound (CEUS) for Post-Interventional Success Control Following Irreversible Electroporation (IRE) of Primary and Secondary Malignant Liver Lesions

2019 ◽  
Vol 28 (3) ◽  
pp. 311-318 ◽  
Author(s):  
Janine Rennert ◽  
Isabel Wiesinger ◽  
Andreas Schicho ◽  
Philipp Wiggermann ◽  
Christian Stroszczynski ◽  
...  
Keyword(s):  
Irreversible Electroporation ◽  
Area Under The Curve ◽  
Liver Lesions ◽  
Metastatic Lesions ◽  
Peak Enhancement ◽  
Contrast Enhanced ◽  
Malignant Lesions ◽  
Perfusion Quantification ◽  
Malignant Liver ◽  
Malignant Liver Lesions

Aim: Evaluation of the post-interventional success following irreversible electroporation (IRE) using a new color coded perfusion quantification software with contrast-enhanced ultrasound (CEUS) in patients with malignant lesions of the liver. Methods: Thirty-eight patients with 68 malignant liver lesions underwent IRE. All malignant lesions were investigated with CEUS before and within 24 hours following IRE to detect residual tumor tissue. The parameters analyzed by color coded perfusion quantification software were: the peak enhancement (pE), time to peak (TTP), mean transit time (mTT), rise (Ri) and wash-in area under the curve (WiAUC). Perfusion in the center, the margins of the lesions and in the surrounding liver were evaluated using these parameters. Results: Hepatocellular carcinoma (HCC) with complete ablation showed significantly different changes between the center and the margin of the lesions for WiAUC (p<0.05) and pE (p<0.01). Also significant differences were noted between the center of the lesions and the surrounded tissue for the same parameters (p<0.01). In the completely ablated metastatic lesions, significant differences were found between the center of the lesion and the margins (p < 0.01) and between the center of the lesion and the surrounding liver (p < 0.05) for WiAUC. mTT, TTP and Ri showed no significant changes between the center of the lesions, margin of the lesions or surrounding tissue. Also, no significant differences were found for these parameters in the different regions of interest for HCC or the metastatic lesions with partial ablation success. Conclusion: CEUS with perfusion imaging is a valuable supporting tool for the post-interventional evaluation of liver lesions following IRE. Focus should be placed on the peak enhancement (pE) and the wash-in area under the curve (WiAUC).

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