Comparison of computed tomography (CT) and contrast-enhanced ultrasound (CEUS) for the quantitative evaluation of an ablation defect following radiofrequency ablation of malignant liver lesions

2017 ◽  
Vol 67 (3-4) ◽  
pp. 445-451 ◽  
Author(s):  
K. Bruenn ◽  
L. Beyer ◽  
M. Haimerl ◽  
B. Pregler ◽  
C. Stroszczynski ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Radiofrequency Ablation ◽  
Quantitative Evaluation ◽  
Liver Lesions ◽  
Contrast Enhanced Ultrasound ◽  
Contrast Enhanced ◽  
Malignant Liver ◽  
Malignant Liver Lesions

Contrast-enhanced ultrasound of malignant liver lesions

2017 ◽  
Vol 43 (4) ◽  
pp. 819-847 ◽  
Author(s):  
Isabelle Durot ◽  
Stephanie R. Wilson ◽  
Jürgen K. Willmann
Keyword(s):  
Liver Lesions ◽  
Contrast Enhanced Ultrasound ◽  
Contrast Enhanced ◽  
Malignant Liver ◽  
Malignant Liver Lesions

scholarly journals Triple-Phase Multidetector Computed Tomography in Distinguishing Canine Hepatic Lesions

Animals ◽  
2020 ◽  
Vol 11 (1) ◽  
pp. 11
Author(s):  
Ladislav Stehlík ◽  
Morena Di Tommaso ◽  
Francesca Del Signore ◽  
Michaela Paninárová ◽  
Rossella Terragni ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Phase Contrast ◽  
Normal Liver ◽  
Liver Parenchyma ◽  
Liver Lesions ◽  
Contrast Enhanced ◽  
Malignant Liver ◽  
Enhanced Computed Tomography ◽  
Contrast Enhanced Computed Tomography ◽  
Malignant Liver Lesions

The liver has a unique vascular supply, and triple-phase contrast-enhanced computed tomography examinations are being performed in order to characterize liver lesions. This study aimed to look for any associations between the attenuation values of liver lesions and their histological classification. The inclusion criteria for this retrospective study were focal or multifocal liver lesions and histological diagnosis. All of the dogs underwent pre-contrast and triple-phase postcontrast computed tomography (CT) examinations with identical timings of the postcontrast series. Thirty-one dogs were included in the study, and various benign and malignant pathologies were identified. The results did not identify any significant differences between the benign and malignant liver lesions, nor between the individual histological diagnoses. Inflammatory lesions were significantly different compared to the normal liver parenchyma, and significant hypoattenuation was found in the portal and delayed venous phases. Hemangiosarcomas were significantly hypoattenuating to the normal liver parenchyma in the pre-contrast and arterial phases, and also to all of the benign lesions in the arterial phase. The other pathologies showed variable attenuation patterns in the different postcontrast phases, and differentiation was not possible. On the basis of this study, triple-phase contrast-enhanced computed tomography cannot differentiate between benign and malignant liver lesions, and biopsy and further histological analysis are necessary.

Characterizing malignant liver lesions with contrast-enhanced ultrasound

2014 ◽  
Vol 75 (3) ◽  
pp. 151-154 ◽  
Author(s):  
Mark Wills ◽  
Chris J Harvey ◽  
Siarhei Kuzmich ◽  
Asim Afaq ◽  
Adrian Lim ◽  
...  
Keyword(s):  
Liver Lesions ◽  
Contrast Enhanced Ultrasound ◽  
Contrast Enhanced ◽  
Malignant Liver ◽  
Malignant Liver Lesions

scholarly journals Diagnostic value of contrast-enhanced ultrasound versus computed tomography for hepatocellular carcinoma: a retrospective, single-center evaluation of 234 patients

2020 ◽  
Vol 48 (6) ◽  
pp. 030006052093015 ◽  
Author(s):  
Vincent Schwarze ◽  
Constantin Marschner ◽  
Wiebke Völckers ◽  
Sergio Grosu ◽  
Giovanna Negrão de Figueiredo ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Hepatocellular Carcinoma ◽  
Predictive Value ◽  
Diagnostic Value ◽  
Ct Scans ◽  
Liver Lesions ◽  
Contrast Enhanced Ultrasound ◽  
Single Center ◽  
Experienced Radiologist ◽  
Contrast Enhanced

Objective Hepatocellular carcinoma (HCC) is the most common cause of primary liver cancer. A major part of diagnostic HCC work-up is based on imaging findings from sonography, computed tomography (CT), or magnetic resonance imaging (MRI) scans. Contrast-enhanced ultrasound (CEUS) allows for the dynamic assessment of the microperfusion pattern of suspicious liver lesions. This study aimed to evaluate the diagnostic value of CEUS compared with CT scans for assessing HCC. Methods We performed a retrospective, single-center study between 2004 and 2018 on 234 patients with suspicious liver lesions who underwent CEUS and CT examinations. All patients underwent native B-mode, color Doppler and CEUS after providing informed consent. Every CEUS examination was performed and interpreted by a single experienced radiologist (European Federation of Societies for Ultrasound in Medicine and Biology level 3). Results CEUS was performed on all included patients without occurrence of any adverse effects. CEUS showed a sensitivity of 94%, a specificity of 70%, a positive predictive value of 93% and a negative predictive value of 72% for analyzing HCC compared with CT as the diagnostic gold standard. Conclusions CEUS has an excellent safety profile and shows a high diagnostic accuracy in assessing HCC compared with corresponding results from CT scans.

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