scholarly journals Optimization of Processing Technology of Instant Sea Cucumber with Fuzzy Mathematic Comprehensive Evaluation by Response Surface Methodology and Exploration on Nutritional Value of Instant Sea Cucumber

2016 ◽  
Vol 22 (5) ◽  
pp. 583-593 ◽  
Author(s):  
Qian Liu ◽  
Jianfeng Sun ◽  
Yahui Pang ◽  
Ziyang Jia
Keyword(s):  
Response Surface Methodology ◽  
Response Surface ◽  
Nutritional Value ◽  
Sea Cucumber ◽  
Comprehensive Evaluation ◽  
Processing Technology ◽  
Fuzzy Mathematic

scholarly journals Optimization of Ultrasound-Assisted Extraction Using Response Surface Methodology for Simultaneous Quantitation of Six Flavonoids in Flos Sophorae Immaturus and Antioxidant Activity

Molecules ◽  
2020 ◽  
Vol 25 (8) ◽  
pp. 1767 ◽  
Author(s):  
Sanhong Fan ◽  
Gege Yang ◽  
Jinhua Zhang ◽  
Jiani Li ◽  
Baoqing Bai
Keyword(s):  
Response Surface Methodology ◽  
Free Radicals ◽  
Response Surface ◽  
Comprehensive Evaluation ◽  
Antioxidant Activities ◽  
Total Flavonoids ◽  
Ultrasound Assisted Extraction ◽  
Antioxidant Power ◽  
Assisted Extraction ◽  
Ultrasound Assisted

Ultrasound-assisted extraction (UAE) was applied to extract rutin (RU), nicotiflorin (NI), narcissoside (NA), kaempferol (KA), isorhamnetin (IS), quercetin (QU), and total flavonoids of Flos Sophorae Immaturus (TFFSI) from Flos Sophorae Immaturus (FSI). Through single factor test and response surface methodology (RSM), the optimal extraction conditions were concluded as follows: ethanol concentration 70%, time 30 min, temperature 61 °C, and liquid/solid ratio 15.30 mL/g, respectively. The actual extraction rates of RU, NI, NA, KA, IS, QU, and TFFSI were 14.6101%, 2.9310%, 7.1987%, 0.1041%, 0.4920%, 2.7998%, and 26.4260%, respectively. The experimental results demonstrated that the extraction method with accuracy and efficiency could be used for the comprehensive evaluation quality control of extracts from FSI. The antioxidant activities of hydroalcoholic extraction from FSI on 1,1-diphenyl-2-picrylhydrazyl (DPPH), 2,2′-azino-bis (3-ethylbenzothiazoline-6-sulfonic acid) (ABTS•+), superoxide anion (•O2−) free radicals, and ferric reducing/antioxidant power (FRAP) were assessed. The results showed that the antioxidation activities of extracts on DPPH, ABTS•+, and •O2− free radicals were reached 89.29%, 97.86%, and 56.61%, and 81.4% in FRAP at 1.0 mg/mL, respectively. The antioxidant capacity of FSI extract was positively correlated with the amount of total flavonoids.

Optimization of the processing technology of Fructus Arctii by response surface methodology

2015 ◽  
Vol 13 (3) ◽  
pp. 222-231 ◽  
Author(s):  
Qi-Di LIU ◽  
Kun-Ming QIN ◽  
Bao-Jia SHEN ◽  
Hao CAI ◽  
Bao-Chang CAI
Keyword(s):  
Response Surface Methodology ◽  
Response Surface ◽  
Processing Technology

scholarly journals Flavonoids from Morus alba L. Leaves: Optimization of Extraction by Response Surface Methodology and Comprehensive Evaluation of Their Antioxidant, Antimicrobial, and Inhibition of α-Amylase Activities through Analytical Hierarchy Process

Molecules ◽  
2019 ◽  
Vol 24 (13) ◽  
pp. 2398 ◽  
Author(s):  
Hao Cui ◽  
Tenghui Lu ◽  
Mingxin Wang ◽  
Xintong Zou ◽  
Yang Zhang ◽  
...  
Keyword(s):  
Response Surface Methodology ◽  
Response Surface ◽  
Analytical Hierarchy Process ◽  
Comprehensive Evaluation ◽  
Antioxidant Activities ◽  
Reducing Power ◽  
Morus Alba ◽  
Extraction Temperature ◽  
Hierarchy Process

To explore the flavonoids from Morus alba L. leaves (MLF), the process of extracting was optimized by a response surface methodology and the antimicrobial and antioxidant activities were evaluated in vitro. The yield of flavonoids reached 50.52 mg g−1 under the optimized extraction conditions (i.e., extraction temperature, 70.85 °C; solvent concentration, 39.30%; extraction time, 120.18 min; and liquid/solid ratio, 34.60:1). The total flavonoids were extracted in organic solvents with various polarities, including petroleum ether (MLFp), ethyl acetate (MLFe), and n-butanol (MLFb). In vitro, the four MLF samples exhibited good antioxidant activities for scavenging of 2, 2′-azinobis-(3-ethylbenz-thiazoline-6-sulphonate) radical, 1, 1-diphenyl-2-picrylhydrazyl radical, and total reducing power. Regarding antimicrobial efficacy, the MLF samples suppressed the development of Staphylococcus aureus, Bacillus subtilis, and Bacillus pumilus. The MLF samples inhibited α-amylase activity to a certain extent. The analytical hierarchy process (AHP) was used to evaluate comprehensively the bioactivities of the MLF samples. The AHP results revealed that the bioactivity comprehensive score (78.83 μg mL−1) of MLFe was optimal among the four MLF samples. Morus alba L. leaves also exhibited non-hemolytic properties. All bioactivities suggested the potential of MLFe as a candidate resource in the food and drug industries.

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