Enrichment of flavonoid‐rich extract from Bidens bipinnata L. by macroporous resin using response surface methodology, UHPLC–Q‐TOF MS/MS‐assisted characterization and comprehensive evaluation of its bioactivities by analytical hierarchy process

2020 ◽  
Vol 34 (11) ◽  
Author(s):  
Xiudong Yang ◽  
Zi‐Fan Bai ◽  
Da‐Wei Zhang ◽  
Yan Zhang ◽  
Hao Cui ◽  
...  
Molecules ◽  
2019 ◽  
Vol 24 (13) ◽  
pp. 2398 ◽  
Author(s):  
Hao Cui ◽  
Tenghui Lu ◽  
Mingxin Wang ◽  
Xintong Zou ◽  
Yang Zhang ◽  
...  

To explore the flavonoids from Morus alba L. leaves (MLF), the process of extracting was optimized by a response surface methodology and the antimicrobial and antioxidant activities were evaluated in vitro. The yield of flavonoids reached 50.52 mg g−1 under the optimized extraction conditions (i.e., extraction temperature, 70.85 °C; solvent concentration, 39.30%; extraction time, 120.18 min; and liquid/solid ratio, 34.60:1). The total flavonoids were extracted in organic solvents with various polarities, including petroleum ether (MLFp), ethyl acetate (MLFe), and n-butanol (MLFb). In vitro, the four MLF samples exhibited good antioxidant activities for scavenging of 2, 2′-azinobis-(3-ethylbenz-thiazoline-6-sulphonate) radical, 1, 1-diphenyl-2-picrylhydrazyl radical, and total reducing power. Regarding antimicrobial efficacy, the MLF samples suppressed the development of Staphylococcus aureus, Bacillus subtilis, and Bacillus pumilus. The MLF samples inhibited α-amylase activity to a certain extent. The analytical hierarchy process (AHP) was used to evaluate comprehensively the bioactivities of the MLF samples. The AHP results revealed that the bioactivity comprehensive score (78.83 μg mL−1) of MLFe was optimal among the four MLF samples. Morus alba L. leaves also exhibited non-hemolytic properties. All bioactivities suggested the potential of MLFe as a candidate resource in the food and drug industries.


2012 ◽  
Vol 170-173 ◽  
pp. 2292-2297
Author(s):  
Jiao Zhang

The application of analytical hierarchy process (AHP) to the risk analysis of port construction project was investigated. Firstly, the happening probabilities of various risk factors during port construction were calculated. Secondly, the aftereffects of the risks were concluded by consulting the experts. Thirdly, the weight of each risk factor was obtained by AHP. Finally, the total risk of port construction project could be evaluated by fuzzy comprehensive evaluation. This risk analysis method was applied to evaluate the total risk of a real port construction project, and the exemplification verified its feasibility.


2013 ◽  
Vol 411-414 ◽  
pp. 2735-2741 ◽  
Author(s):  
Yong Hua Wang ◽  
Guo Liang Luo

Based on the matter-element extension model, this paper first builds a set of reasonable power quality evaluation index system, and then determines the index value through the analytical hierarchy process (AHP), and finally makes a comprehensive evaluation of power supply quality. With an example based on, this paper will prove the feasibility of matter-extension model supplied in power quality evaluation.


2006 ◽  
Vol 315-316 ◽  
pp. 864-867
Author(s):  
Shi An ◽  
J. Wang ◽  
J.P. Qian

Recognizing and evaluating the development level of a country’s precise finishing industry, is the prerequisite to the country’s decision-making on the development planning and guiding policies in this industry. This paper presents a Fuzzy Analytical Hierarchy Process (FAHP) Model on the base of “Expert Knowledge”. This model combines the advantages of Fuzzy Evaluation Method and Analytical Hierarchy Process (AHP), and can give relatively reliable evaluation results with incomplete information of the evaluation criteria. The application of the FAHP Model provide reliable comprehensive evaluation data.


2014 ◽  
Vol 687-691 ◽  
pp. 1560-1563
Author(s):  
Han Cong Tang ◽  
Yan An Dong

This paper presents three models as a potential decision making method for selecting the best baseball, field hockey, and women’s basketball NCAA Division I coaches. Five indicators, synthesized coaching efficiency, winning percentage, consecutive championship, achievement index and gender, are introduced to give a comprehensive evaluation of coaching ability. The preliminary served as a filter model to screen out less capable coaches and a robust ranking within top 10 is achieved. The Data Envelopment Analysis (DEA) model takes the time line horizon into consideration, and helps find less efficient coaches. By comparing the first two models, we obtain a reasonable assessment of coaches from different time period. Finally, by applying the Analytical Hierarchy Process (AHP), minor changes in judgment matrices can be made to adjust the ratio of male to female in the top 5 coaches.


Molecules ◽  
2020 ◽  
Vol 25 (8) ◽  
pp. 1767 ◽  
Author(s):  
Sanhong Fan ◽  
Gege Yang ◽  
Jinhua Zhang ◽  
Jiani Li ◽  
Baoqing Bai

Ultrasound-assisted extraction (UAE) was applied to extract rutin (RU), nicotiflorin (NI), narcissoside (NA), kaempferol (KA), isorhamnetin (IS), quercetin (QU), and total flavonoids of Flos Sophorae Immaturus (TFFSI) from Flos Sophorae Immaturus (FSI). Through single factor test and response surface methodology (RSM), the optimal extraction conditions were concluded as follows: ethanol concentration 70%, time 30 min, temperature 61 °C, and liquid/solid ratio 15.30 mL/g, respectively. The actual extraction rates of RU, NI, NA, KA, IS, QU, and TFFSI were 14.6101%, 2.9310%, 7.1987%, 0.1041%, 0.4920%, 2.7998%, and 26.4260%, respectively. The experimental results demonstrated that the extraction method with accuracy and efficiency could be used for the comprehensive evaluation quality control of extracts from FSI. The antioxidant activities of hydroalcoholic extraction from FSI on 1,1-diphenyl-2-picrylhydrazyl (DPPH), 2,2′-azino-bis (3-ethylbenzothiazoline-6-sulfonic acid) (ABTS•+), superoxide anion (•O2−) free radicals, and ferric reducing/antioxidant power (FRAP) were assessed. The results showed that the antioxidation activities of extracts on DPPH, ABTS•+, and •O2− free radicals were reached 89.29%, 97.86%, and 56.61%, and 81.4% in FRAP at 1.0 mg/mL, respectively. The antioxidant capacity of FSI extract was positively correlated with the amount of total flavonoids.


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