scholarly journals Intravitreal Therapy of Endogenous Endophthalmitis due to Urosepsis – A Case Report

2019 ◽  
Vol 75 (5) ◽  
pp. 277-282
Author(s):  
Jela Valášková ◽  
Jana Sitárová ◽  
Vladimír Krásnik

This case report describes a case of endogenous endophthalmitis in a 58 year old man upon a background of urosepsis and bronchitis. The patient was hospitalised at a department of internal medicine in another hospital. The day after admittance he was sent to our clinic for a consultation examination due to worsening of vision and pain in the left eye. The condition was diagnosed as endogenous endophthalmitis. Visual acuity at the first examination was hand movement in front of the eye. Intravitreal therapy was commenced with a combination of two antibiotics (ceftazidime 2 mg/ 0.1 ml and vancomycin 1 mg/0.1 ml) and an antimycotic agent (amphotericin B 10 μg/0.1 ml). Over the course of two weeks the patient received this antibiotic treatment intravitreally 3x in total. During the first application of antibiotics, material was sampled from the anterior chamber of the eye for a microbiological examination – the result was negative. The blood culture tested positive for staphylococcus aureus. Intravenous application of antibiotics (gentamicin 240 mg i.v. every 24 hours and amoxicillin with clavulanic acid 1.2 g i.v. every 8 hours) was set for two weeks, and then antibiotic treatment continued (ciprofloxacin 500 mg every 12 hours) and antimycotic therapy (itraconazole 100 mg every 12 hours) orally for 2 months. Four weeks after the beginning of therapy, visual acuity in the left eye was 20/100 and after two months 20/40. The study emphasises the advantage of multi-disciplinary co-operation.

2020 ◽  
Vol 27 (1) ◽  
pp. 10
Author(s):  
Timothé Debré ◽  
Loubna El Mansouf ◽  
Laila Meyaz ◽  
Saida Moussaceb ◽  
Alp Alantar

Introduction: Impetiginization is defined as a surinfection of Staphylococcus aureus on a preexistent dermatosis: Observation: A 19-year-old patient in good general health was admitted to general emergency and then hospitalized in internal medicine for an abscess of the labial commissure. The anamnesis revealed a 24 hours old insect bite. An abscess of the labial commissure of 20 mm in diameter with a necrotic surroundings and associated induration was observed. After 3 days of antibiotic i.v (amoxicillin + clavulanic acid), the patient went home. By 14 days, healing was complete. Bacteriological examination detected numerous staphylococcus aureus (SA) that were sensitive to meticillin. Discussion: SA by their pathogenicity are responsible for many infections, potentially serious. For several decades, mainly in hospitals, SA have acquired resistance to penicillins A and G. Infections considered as banal could evolve into very serious necrotic infections. Conclusion: This case is unusual because of its localization and its quick evolution on a young adult. It underlines the importance of early bacteriological sampling before the introduction of probabilistic antibiotherapy in order to anticipate extremely serious necrotic infections that may lead to aesthetic and functional sequelae.


2020 ◽  
pp. 247412642094663
Author(s):  
Roma B. Pegany ◽  
Roshan T. George ◽  
Alice Yang Zhang

Purpose: This case report describes a rare organism causing endogenous endophthalmitis in a patient with sickle cell disease. Methods: A case report was conducted. Results: A 41-year-old man with sickle cell disease presented with acute onset of blurry vision of the right eye. His visual acuity was counting fingers in the right eye and 20/20 in the left eye. He had ophthalmic findings of hypopyon and vitritis in the right eye, consistent with endophthalmitis. He was treated with intravitreal and systemic antibiotics. Vitreous cultures grew Bordetella holmesii. His visual acuity at follow-up visits improved to 20/40 in the setting of improved vitritis. Conclusions: This is the first case describing B holmesii, a rare causative organism of endogenous endophthalmitis, in a patient with sickle cell disease. More studies are needed to improve the early detection and treatment of this unusual organism.


Background: Binasal Occlusion (BNO) is a clinical technique used by many neurorehabilitative optometrists in patients with mild traumatic brain injury (mTBI) and increased visual motion sensitivity (VMS) or visual vertigo. BNO is a technique in which partial occluders are added to the spectacle lenses to suppress the abnormal peripheral visual motion information. This technique helps in reducing VMS symptoms (i.e., nausea, dizziness, balance difficulty, visual confusion). Case Report: A 44-year-old AA female presented for a routine eye exam with a history of mTBI approximately 33 years ago. She was suffering from severe dizziness for the last two years that was adversely impacting her ADLs. The dizziness occurred in all body positions and all environments throughout the day. She was diagnosed with vestibular hypofunction and had undergone vestibular therapy but reported little improvement. Neurological exam revealed dizziness with both OKN drum and hand movement, especially in the left visual field. BNO technique resulted in immediate relief of her dizziness symptoms. Conclusion: To our knowledge, this is the first case that illustrates how the BNO technique in isolation can be beneficial for patients with mTBI and vestibular hypofunction. It demonstrates the success that BNO has in filtering abnormal peripheral visual motion in these patients.


Sign in / Sign up

Export Citation Format

Share Document