scholarly journals Clinical Utility of the Korean Version of the WHO Adult Attention-Deficit/Hyperactivity Disorder Self-Report Scale Screener

2018 ◽  
Vol 15 (3) ◽  
pp. 325-329 ◽  
Author(s):  
Simyang Heo ◽  
Ji-Hae Kim ◽  
Yoo-Sook Joung ◽  
Won-Ik Lee ◽  
Joo-Jin Kim ◽  
...  
Keyword(s):  
Attention Deficit Hyperactivity Disorder ◽  
Attention Deficit ◽  
Clinical Utility ◽  
Self Report ◽  
Hyperactivity Disorder ◽  
Korean Version

Clinical Utility of Lisdexamfetamine for the Management of Attention-Deficit Hyperactivity Disorder

2012 ◽  
Vol 4 ◽  
pp. CMT.S8706
Author(s):  
M. Nguyen ◽  
M.A. Shapiro ◽  
S. Tharani
Keyword(s):  
Attention Deficit Hyperactivity Disorder ◽  
Attention Deficit ◽  
Clinical Utility ◽  
Adhd Symptoms ◽  
First Line ◽  
Duration Of Action ◽  
Once Daily ◽  
Hyperactivity Disorder ◽  
Hydrolytic Reaction ◽  
Proven Efficacy

ADHD is the most common neuropsychiatry disorder affecting children and adolescents, and may cause impairment in many domains of social and occupational functioning. Despite proven efficacy of existing treatments, recent focus has been on the development of newer, once-daily medications. Lisdexamfetamine (LDX) was first released in 2007 and is approved for the treatment of ADHD in ages 6 and above. LDX is a uniquely formulated stimulant, a prodrug which requires an enzymatic hydrolytic reaction to be converted to active dextroamphetamine. LDX has a longer duration of action compared to other stimulants and has less potential to be misused or abused. LDX has repeatedly demonstrated improvement in ADHD symptoms compared to placebo, and seems to be at least as effective as other stimulants. LDX still carries the risks and disadvantages of other stimulants and may be more expensive than other stimulants. LDX can be expected to be increasingly used as a first-line agent for the treatment of ADHD.

scholarly journals Reward sensitivity, affective neuroscience personality, symptoms of attention-deficit/hyperactivity disorder, and TPH2-703G/T (rs4570625) genotype

2020 ◽  
Vol 32 (5) ◽  
pp. 247-256 ◽  
Author(s):  
Aleksander Pulver ◽  
Evelyn Kiive ◽  
Jaanus Harro
Keyword(s):  
Attention Deficit Hyperactivity Disorder ◽  
Attention Deficit ◽  
Tryptophan Hydroxylase ◽  
Negative Relationship ◽  
Reward Sensitivity ◽  
Self Report ◽  
Measurement Scale ◽  
Health Study ◽  
Affective Neuroscience ◽  
Hyperactivity Disorder

AbstractObjective:Reward sensitivity is an increasingly used construct in psychiatry, yet its possible inner structure and relationship with other affective variables are not well known.Methods:A reward sensitivity measurement scale was constructed on the basis of large item pool collected from birth cohort representative samples (the Estonian Children Personality Behaviour and Health Study; original n = 1238). Affective Neuroscience Personality Scale (ANPS) and the Adult Attention deficit hyperactivity disorder (ADHD) Self-Report Scale (ASRS) were administered in young adulthood. A variant (rs4570625) of the gene encoding tryptophan hydroxylase 2 (TPH2) that is responsible for the synthesis of central serotonin was genotyped.Results:Reward sensitivity consisted of two orthogonal components, operationally defined as Openness to Rewards and Insatiability by Reward, that respectively characterise the striving towards multiple rewards and the strong pursuit and fixation to a particular reward. While SEEKING and PLAY (and to lower extent CARE) of the ANPS co-varied with Openness to Rewards, FEAR, SADNESS, and ANGER were related to Insatiability by Reward. The total score of ASRS was moderately correlated with Insatiability by Reward, while the association with Openness to Rewards was negligible. However, ASRS Inattention had some negative relationship with the Social Experience facet of Openness to Rewards. The T/T homozygotes for the TPH2 promoter polymorphism had lower Insatiability by Reward but not Openness to Rewards.Conclusions:Behaviours sensitive to rewards are separable to the components of variability and fixation, and these components are differentially related to affective aspects of personality, attention, and hyperactivity as well as to TPH2 genotype.

Risk factors influencing severity of attention deficit hyperactivity disorder in a sample of preparatory school students in Cairo

2018 ◽  
Vol 23 (4) ◽  
pp. 542-555 ◽  
Author(s):  
Hisham Ramy ◽  
Mona El Sheikh ◽  
Marwa Sultan ◽  
Rasha Bassim ◽  
Maissa Eid ◽  
...  
Keyword(s):  
Risk Factors ◽  
Attention Deficit Hyperactivity Disorder ◽  
Behavioral Problems ◽  
Attention Deficit ◽  
Female Gender ◽  
Intellectual Ability ◽  
Self Report ◽  
Short Version ◽  
School Students ◽  
Hyperactivity Disorder

Background: Attention deficit hyperactivity disorder (ADHD) is one of the most common childhood psychiatric disorders. Severity of symptoms is associated with more behavioral problems, poor academic performance, and persistence of symptoms into adulthood. Methods: To examine the clinical and social correlates that may be identified as risk factors associated with ADHD severity in a sample of adolescent ADHD school students. A total of 925 students were recruited from two public and two private schools from eastern Cairo. They were interviewed using Conners-Wells Adolescent Self-Report—short version (CASS-S); students scoring more than 65 were further interviewed with Kiddie Schedule for Affective Disorders and Schizophrenia—present and lifetime version (K-SADS-PL) to confirm the diagnosis, then Conners-Wells Adolescent Self-Report—long version (CASS-L) to assess severity and Wechsler Intelligence Scale for Children (WISC) to ascertain intellectual ability. Results: About 10.3% of cases were severe, 5.7% were moderate, and 83.9% were mild. Severity was significantly associated with female gender, psychiatric comorbidity, family problems, conduct symptoms, and poor anger management. Diagnostic and Statistical Manual of Mental Disorders (4th ed.) ( DSM-IV) hyperactive–impulsive type was the only predictive factor of ADHD severity. Conclusions: The diagnosis of hyperactive–impulsive subtype may predict the severity of ADHD symptoms.

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