scholarly journals NONLINEAR INTERACTION OF ELECTROMAGNETIC RADIATION AT THE CELL MEMBRANE LEVEL: RESPONSE TO STOCHASTIC FIELDS

2011 ◽  
Vol 33 ◽  
pp. 45-67 ◽  
Author(s):  
Assunta De Vita ◽  
Rocco Paolo Croce ◽  
Innocenzo M. Pinto ◽  
Bisceglia Bruno
Keyword(s):  
Cell Membrane ◽  
Electromagnetic Radiation ◽  
Nonlinear Interaction ◽  
Stochastic Fields ◽  
Cell Membrane Level ◽  
Membrane Level

X-Ray and Fluorescence Studies on Phospholipid Bilayers. IX. Interactions with Pentachlorophenol

1990 ◽  
Vol 45 (3-4) ◽  
pp. 265-272 ◽  
Author(s):  
M. Suwalsky ◽  
M. A. Espinoza ◽  
M. Bagnara ◽  
C. P. Sotomayor
Keyword(s):  
Cell Membrane ◽  
Phospholipid Bilayers ◽  
Erythrocyte Membranes ◽  
X Ray Diffraction ◽  
X Ray ◽  
Fluorescence Studies ◽  
Human Erythrocyte Membranes ◽  
Cell Membrane Level ◽  
Membrane Level ◽  
Sodium Form

Abstract Pentachlorophenol (PCP) is a widely used and highly toxic fungicide. Its toxicity is mainly expressed at the cell membrane level. It is, therefore, of interest to test its ability to alter the lipid bilayer organization. The present study was performed by X-ray diffraction techniques on dimyristoylphosphatidylethanolamine (DMPE) and dimyristoylphosphatidylcholine (DMPC) bilayers and by fluorescence on DMPC liposomes. These two phospholipids are respectively found at the inner and outer monolayers of human erythrocyte membranes. Each type of phospholipid was made to interact with different concentrations of the sodium form of PCP in absence and in presence of water. It was found that PCP significatively affected the structure of both phospholipids, being the damage much higher in DM PC bilayers.

Thyroid Autoregulation: Evidence for an Action of Iodoarachidonates and Iodide at the Cell Membrane Level

1991 ◽  
Vol 23 (07) ◽  
pp. 321-325 ◽  
Author(s):  
L. Krawiec ◽  
H. Chester ◽  
Laura Bocanera ◽  
Laura Pregliasco ◽  
G. Juvenal ◽  
...  
Keyword(s):  
Cell Membrane ◽  
Cell Membrane Level ◽  
Membrane Level

scholarly journals Differential Cytotoxicity of MEX: a Component of Neem Oil Whose Action Is Exerted at the Cell Membrane Level

Molecules ◽  
2008 ◽  
Vol 14 (1) ◽  
pp. 122-132 ◽  
Author(s):  
Francesca Ricci ◽  
Valerio Berardi ◽  
Gianfranco Risuleo
Keyword(s):  
Cell Membrane ◽  
Neem Oil ◽  
Cell Membrane Level ◽  
Membrane Level

scholarly journals Adhesion force spectroscopy with nanostructured colloidal probes reveals nanotopography-dependent early mechanotransductive interactions at the cell membrane level

Nanoscale ◽  
2020 ◽  
Vol 12 (27) ◽  
pp. 14708-14723 ◽  
Author(s):  
M. Chighizola ◽  
A. Previdi ◽  
T. Dini ◽  
C. Piazzoni ◽  
C. Lenardi ◽  
...  
Keyword(s):  
Cell Membrane ◽  
Adhesion Force ◽  
Force Spectroscopy ◽  
Force Loading ◽  
Cellular Mechanosensing ◽  
Colloidal Probes ◽  
Cell Membrane Level ◽  
Membrane Level ◽  
Adhesion Site

The study shows, by exploiting a novel adhesion force spectroscopy approach, that microenvironmental nanotopography impacts strongly on integrin-mediated cellular mechanosensing, by influencing adhesion site force loading dynamics.

scholarly journals PC 12 Pheochromocytoma Cell Response to Super High Frequency Terahertz Radiation from Synchrotron Source

Cancers ◽  
2019 ◽  
Vol 11 (2) ◽  
pp. 162 ◽  
Author(s):  
Palalle Perera ◽  
Dominique Appadoo ◽  
Samuel Cheeseman ◽  
Jason Wandiyanto ◽  
Denver Linklater ◽  
...  
Keyword(s):  
Electron Microscopy ◽  
Cell Membrane ◽  
Electromagnetic Radiation ◽  
High Frequency ◽  
Biological Effects ◽  
Cell Membrane Permeability ◽  
Temporary Increase ◽  
Thz Radiation ◽  
Synchrotron Source ◽  
Pc 12 Cells

High frequency (HF) electromagnetic fields (EMFs) have been widely used in many wireless communication devices, yet within the terahertz (THz) range, their effects on biological systems are poorly understood. In this study, electromagnetic radiation in the range of 0.3–19.5 × 1012 Hz, generated using a synchrotron light source, was used to investigate the response of PC 12 neuron-like pheochromocytoma cells to THz irradiation. The PC 12 cells remained viable and physiologically healthy, as confirmed by a panel of biological assays; however, exposure to THz radiation for 10 min at 25.2 ± 0.4 °C was sufficient to induce a temporary increase in their cell membrane permeability. High-resolution transmission electron microscopy (TEM) confirmed cell membrane permeabilization via visualisation of the translocation of silica nanospheres (d = 23.5 ± 0.2 nm) and their clusters (d = 63 nm) into the PC 12 cells. Analysis of scanning electron microscopy (SEM) micrographs revealed the formation of atypically large (up to 1 µm) blebs on the surface of PC 12 cells when exposed to THz radiation. Long-term analysis showed no substantial differences in metabolic activity between the PC 12 cells exposed to THz radiation and untreated cells; however, a higher population of the THz-treated PC 12 cells responded to the nerve growth factor (NGF) by extending longer neurites (up to 0–20 µm) compared to the untreated PC12 cells (up to 20 µm). These findings present implications for the development of nanoparticle-mediated drug delivery and gene therapy strategies since THz irradiation can promote nanoparticle uptake by cells without causing apoptosis, necrosis or physiological damage, as well as provide a deeper fundamental insight into the biological effects of environmental exposure of cells to electromagnetic radiation of super high frequencies.

Review : Role of polyamines in chilling injury of fruit and vegetables/Revisión: El papel de las poliaminas en los daños por frío de frutas y hortalizas

1996 ◽  
Vol 2 (4) ◽  
pp. 195-199 ◽  
Author(s):  
M. Serrano ◽  
M.C. Martínez-Madrid ◽  
G. Martínez ◽  
F. Riquelme ◽  
M.T. Pretel ◽  
...  
Keyword(s):  
Cell Membrane ◽  
Low Temperatures ◽  
Chilling Injury ◽  
Fruit And Vegetables ◽  
Negative Effects ◽  
Physiological Alterations ◽  
Quantitative Changes ◽  
Subtropical Fruit ◽  
Cell Membrane Level

Some tropical and subtropical fruit and vegetables suffer chilling injuries (CI) when exposed to low (above freezing) temperatures. The symptoms of such injuries vary between species, although they usually involve staining of the peel and internal browing, and are related to important modi fications at the cell membrane level. The polyamines putrescine, spermidine and spermine, have an antisenescent action because of their capacity to link with anionic compounds in the cell membrane and to capture free radicals, thus stabilizing the lipid bilayer and preventing membrane deterioration. This paper reviews the mechanism responsible for the physiological alterations produced by chilling, the role of polyamines and the quantitative changes they undergo in the affected tissues. Finally, it describes the possibility of using different treatments to reduce the negative effects of low temperatures and their influence on polyamine levels.

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