scholarly journals Differential Cytotoxicity of MEX: a Component of Neem Oil Whose Action Is Exerted at the Cell Membrane Level

Molecules ◽  
2008 ◽  
Vol 14 (1) ◽  
pp. 122-132 ◽  
Author(s):  
Francesca Ricci ◽  
Valerio Berardi ◽  
Gianfranco Risuleo
Keyword(s):  
Cell Membrane ◽  
Neem Oil ◽  
Cell Membrane Level ◽  
Membrane Level

X-Ray and Fluorescence Studies on Phospholipid Bilayers. IX. Interactions with Pentachlorophenol

1990 ◽  
Vol 45 (3-4) ◽  
pp. 265-272 ◽  
Author(s):  
M. Suwalsky ◽  
M. A. Espinoza ◽  
M. Bagnara ◽  
C. P. Sotomayor
Keyword(s):  
Cell Membrane ◽  
Phospholipid Bilayers ◽  
Erythrocyte Membranes ◽  
X Ray Diffraction ◽  
X Ray ◽  
Fluorescence Studies ◽  
Human Erythrocyte Membranes ◽  
Cell Membrane Level ◽  
Membrane Level ◽  
Sodium Form

Abstract Pentachlorophenol (PCP) is a widely used and highly toxic fungicide. Its toxicity is mainly expressed at the cell membrane level. It is, therefore, of interest to test its ability to alter the lipid bilayer organization. The present study was performed by X-ray diffraction techniques on dimyristoylphosphatidylethanolamine (DMPE) and dimyristoylphosphatidylcholine (DMPC) bilayers and by fluorescence on DMPC liposomes. These two phospholipids are respectively found at the inner and outer monolayers of human erythrocyte membranes. Each type of phospholipid was made to interact with different concentrations of the sodium form of PCP in absence and in presence of water. It was found that PCP significatively affected the structure of both phospholipids, being the damage much higher in DM PC bilayers.

Thyroid Autoregulation: Evidence for an Action of Iodoarachidonates and Iodide at the Cell Membrane Level

1991 ◽  
Vol 23 (07) ◽  
pp. 321-325 ◽  
Author(s):  
L. Krawiec ◽  
H. Chester ◽  
Laura Bocanera ◽  
Laura Pregliasco ◽  
G. Juvenal ◽  
...  
Keyword(s):  
Cell Membrane ◽  
Cell Membrane Level ◽  
Membrane Level

scholarly journals Adhesion force spectroscopy with nanostructured colloidal probes reveals nanotopography-dependent early mechanotransductive interactions at the cell membrane level

Nanoscale ◽  
2020 ◽  
Vol 12 (27) ◽  
pp. 14708-14723 ◽  
Author(s):  
M. Chighizola ◽  
A. Previdi ◽  
T. Dini ◽  
C. Piazzoni ◽  
C. Lenardi ◽  
...  
Keyword(s):  
Cell Membrane ◽  
Adhesion Force ◽  
Force Spectroscopy ◽  
Force Loading ◽  
Cellular Mechanosensing ◽  
Colloidal Probes ◽  
Cell Membrane Level ◽  
Membrane Level ◽  
Adhesion Site

The study shows, by exploiting a novel adhesion force spectroscopy approach, that microenvironmental nanotopography impacts strongly on integrin-mediated cellular mechanosensing, by influencing adhesion site force loading dynamics.

Review : Role of polyamines in chilling injury of fruit and vegetables/Revisión: El papel de las poliaminas en los daños por frío de frutas y hortalizas

1996 ◽  
Vol 2 (4) ◽  
pp. 195-199 ◽  
Author(s):  
M. Serrano ◽  
M.C. Martínez-Madrid ◽  
G. Martínez ◽  
F. Riquelme ◽  
M.T. Pretel ◽  
...  
Keyword(s):  
Cell Membrane ◽  
Low Temperatures ◽  
Chilling Injury ◽  
Fruit And Vegetables ◽  
Negative Effects ◽  
Physiological Alterations ◽  
Quantitative Changes ◽  
Subtropical Fruit ◽  
Cell Membrane Level

Some tropical and subtropical fruit and vegetables suffer chilling injuries (CI) when exposed to low (above freezing) temperatures. The symptoms of such injuries vary between species, although they usually involve staining of the peel and internal browing, and are related to important modi fications at the cell membrane level. The polyamines putrescine, spermidine and spermine, have an antisenescent action because of their capacity to link with anionic compounds in the cell membrane and to capture free radicals, thus stabilizing the lipid bilayer and preventing membrane deterioration. This paper reviews the mechanism responsible for the physiological alterations produced by chilling, the role of polyamines and the quantitative changes they undergo in the affected tissues. Finally, it describes the possibility of using different treatments to reduce the negative effects of low temperatures and their influence on polyamine levels.

Sarcolemmal permeability changes during early myocardial anoxia

1978 ◽  
Vol 36 (2) ◽  
pp. 642-643
Author(s):  
M. Ashraf ◽  
L. Landa ◽  
L. Nimmo ◽  
C. M. Bloor
Keyword(s):  
Cell Membrane ◽  
Membrane Permeability ◽  
Coronary Artery Occlusion ◽  
Artery Occlusion ◽  
Cell Membrane Permeability ◽  
Enzyme Release ◽  
Sprague Dawley ◽  
Sprague Dawley Rats ◽  
Sarcolemmal Permeability ◽  
Membrane Changes

Following coronary artery occlusion, the myocardial cells lose intracellular enzymes that appear in the serum 3 hrs later. By this time the cells in the ischemic zone have already undergone irreversible changes, and the cell membrane permeability is variably altered in the ischemic cells. At certain stages or intervals the cell membrane changes, allowing release of cytoplasmic enzymes. To correlate the changes in cell membrane permeability with the enzyme release, we used colloidal lanthanum (La+++) as a histological permeability marker in the isolated perfused hearts. The hearts removed from sprague-Dawley rats were perfused with standard Krebs-Henseleit medium gassed with 95% O2 + 5% CO2. The hypoxic medium contained mannitol instead of dextrose and was bubbled with 95% N2 + 5% CO2. The final osmolarity of the medium was 295 M osmol, pH 7. 4.

Flagellar Attachment in Selected Trypanosomes

1973 ◽  
Vol 31 ◽  
pp. 496-497
Author(s):  
J. J. Paulin
Keyword(s):  
Cell Membrane ◽  
Lateral Surface ◽  
The Body ◽  
Flagellar Pocket ◽  
Integral Component ◽  
Free Flagellum ◽  
Flagellar Axoneme

Movement in epimastigote and trypomastigote stages of trypanosomes is accomplished by planar sinusoidal beating of the anteriorly directed flagellum and associated undulating membrane. The flagellum emerges from a bottle-shaped depression, the flagellar pocket, opening on the lateral surface of the cell. The limiting cell membrane envelopes not only the body of the trypanosome but is continuous with and insheathes the flagellar axoneme forming the undulating membrane. In some species a paraxial rod parallels the axoneme from its point of emergence at the flagellar pocket and is an integral component of the undulating membrane. A portion of the flagellum may extend beyond the anterior apex of the cell as a free flagellum; the length is variable in different species of trypanosomes.

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