Effect of dietary omega-3 fatty acids on red blood cell lipid composition and plasma metabolites in the cockatiel, Nymphicus hollandicus1

2012 ◽  
Vol 90 (9) ◽  
pp. 3068-3079 ◽  
Author(s):  
C. R. Heinze ◽  
M. G. Hawkins ◽  
L. A. Gillies ◽  
X. Wu ◽  
R.L Walzem ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Blood Cell ◽  
Red Blood Cell ◽  
Lipid Composition ◽  
Plasma Metabolites ◽  
Omega 3 Fatty Acids ◽  
Omega 3 ◽  
Cell Lipid

Red blood cell omega-3 fatty acids and the risk of ventricular arrhythmias in patients with heart failure

2008 ◽  
Vol 155 (6) ◽  
pp. 971-977 ◽  
Author(s):  
Matthias Wilhelm ◽  
Rueth Tobias ◽  
Fatima Asskali ◽  
Robert Kraehner ◽  
Simone Kuly ◽  
...  
Keyword(s):  
Heart Failure ◽  
Fatty Acids ◽  
Blood Cell ◽  
Red Blood Cell ◽  
Ventricular Arrhythmias ◽  
Omega 3 Fatty Acids ◽  
Omega 3 ◽  
Patients With Heart Failure

scholarly journals Six‐Year Change in Red Blood Cell Omega‐3 and Trans Fatty Acids in the Framingham Heart Study

2010 ◽  
Vol 24 (S1) ◽  
Author(s):  
William S Harris ◽  
James V Pottala ◽  
Ramachandran S Vasan ◽  
Martin G Larson ◽  
Sander J Robins
Keyword(s):  
Fatty Acids ◽  
Blood Cell ◽  
Red Blood Cell ◽  
Framingham Heart Study ◽  
Trans Fatty Acids ◽  
Omega 3 ◽  
Heart Study

THE RELATIONSHIP OF OMEGA 3 POLYUNSATURATED FATTY ACIDS IN RED BLOOD CELL MEMBRANES WITH COGNITIVE FUNCTION AND BRAIN STRUCTURE: A REVIEW FOCUSSED ON ALZHEIMER’S DISEASE

2017 ◽  
pp. 1-7
Author(s):  
C. Hooper ◽  
P. De Souto Barreto ◽  
M. Pahor ◽  
M. Weiner ◽  
B. Vellas
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Fatty Acids ◽  
Cognitive Function ◽  
Blood Cell ◽  
Polyunsaturated Fatty Acids ◽  
Red Blood Cell ◽  
Omega 3 ◽  
Research Attention ◽  
Pufa Supplementation

Significant research attention has focussed on the identification of nutraceutical agents for the prevention of cognitive decline as a natural means of cognitive preservation in the elderly. There is some evidence for a reduction of brain omega 3 polyunsaturated fatty acids (n-3 PUFAs) in normal aging and in Alzheimer’s disease. n-3 PUFAs exhibit anti-inflammatory and anti-amyloidogenic properties as well as being able to reduce tau phosphorylation. Many observational studies have demonstrated a link between n-3 PUFAs and cognitive aging, and some, but not all, randomized controlled trials have demonstrated a benefit of n-3 PUFA supplementation on cognition, particularly in those subjects with mild cognitive impairment. The identification of a biomarker that reflects n-3 PUFA intake over time and consequent tissue levels is required. In this narrative review we discuss the evidence associating red blood cell membrane n-3 PUFAs with cognitive function and structural brain changes associated with Alzheimer’s disease. Key words: Docosahexaenoic acid, omega 3 polyunsaturated fatty aci

scholarly journals Red Blood Cell Membrane Fatty Acids in U. S. Blood Donors (P06-123-19)

2019 ◽  
Vol 3 (Supplement_1) ◽  
Author(s):  
Carissa Powers ◽  
David Scully ◽  
Rosemary Schleicher
Keyword(s):  
Gender Differences ◽  
Fatty Acids ◽  
Fatty Acid ◽  
Blood Cell ◽  
Red Blood Cell ◽  
Blood Donors ◽  
Saturated Fatty Acids ◽  
Omega 3 ◽  
Cardiac Events ◽  
Membrane Fatty Acids

Abstract Objectives The purpose of this study was to use a newly validated method for measuring 21 cis-fatty acids in red blood cell (RBC) membranes to investigate race-ethnic and gender differences in saturated fatty acids (SFA), monounsaturated fatty acids (MUFA), and polyunsaturated fatty acids (PUFA). In addition, two long-chain PUFA, namely, eicosapentaenoic (EPA) and docosahexaenoic acid (DHA), were summed to provide an Omega-3 Index for each participant. This index is considered a cardiovascular risk factor. Methods Units (n = 120) of whole blood in EDTA were purchased from BioIVT (Westbury, NY). The demographic make-up of the set was 60:60 men: women. Of the 120 blood donors, 37% were black, 29% were white, and 34% were Hispanic. Average ages were 44 y (black), 48 y (white), and 43 y (Hispanic). Upon arrival, units were washed, treated with 1% BHT, and packed RBC were frozen until time of analysis. Hydrolysis of esters, derivitization with pentafluorobenzyl bromide, gas chromatography, and mass spectrometric detection were carried out to measure the 21 most abundant cis-fatty acid concentrations in RBC, which were converted to weight percentages of total. For the Omega-3 Index, the percentage of totals calculated for EPA and DHA were summed. Results There were few small (≤1%) race-ethnic differences and no gender differences in the proportions of fatty acids as SFA, MUFA, or PUFA; overall these averaged (SD) 44% (1%), 16% (1%), and 40% (1%), respectively. The Omega-3 Index averaged (SD) 3.5% (1%). One blood donor reached the suggested goal of ≥ 8%, which is associated with low risk for cardiac events. Conclusions This small study was undertaken in advance of the U.S. nationally representative survey, NHANES 2019–2020, in which RBC membrane fatty acids will be measured in the same laboratory. It will be interesting to learn whether NHANES will confirm the mostly null demographic findings in RBC fatty acid percentages and the low average Omega-3 Index. Funding Sources None.

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