scholarly journals Diabetes Prevention in the Real World: Effectiveness of Pragmatic Lifestyle Interventions for the Prevention of Type 2 Diabetes and of the Impact of Adherence to Guideline Recommendations

Diabetes Care ◽  
2014 ◽  
Vol 37 (4) ◽  
pp. 922-933 ◽  
Author(s):  
Alison J. Dunkley ◽  
Danielle H. Bodicoat ◽  
Colin J. Greaves ◽  
Claire Russell ◽  
Thomas Yates ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Real World ◽  
Diabetes Prevention ◽  
Lifestyle Interventions ◽  
The Real ◽  
The Impact

scholarly journals Type 2 Diabetes Prevention in the Real World: Three-year results of the GOAL Lifestyle Implementation Trial

Diabetes Care ◽  
2009 ◽  
Vol 32 (8) ◽  
pp. 1418-1420 ◽  
Author(s):  
P. Absetz ◽  
B. Oldenburg ◽  
N. Hankonen ◽  
R. Valve ◽  
H. Heinonen ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Real World ◽  
Diabetes Prevention ◽  
The Real ◽  
Type 2 Diabetes Prevention ◽  
Implementation Trial

scholarly journals Type 2 Diabetes Prevention in the "Real World": One-year results of the GOAL Implementation Trial

Diabetes Care ◽  
2007 ◽  
Vol 30 (10) ◽  
pp. 2465-2470 ◽  
Author(s):  
P. Absetz ◽  
R. Valve ◽  
B. Oldenburg ◽  
H. Heinonen ◽  
A. Nissinen ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Real World ◽  
Diabetes Prevention ◽  
The Real ◽  
Type 2 Diabetes Prevention ◽  
One Year ◽  
Goal Implementation ◽  
Implementation Trial

The Impact of Hypoglycemia on Productivity Loss and Utility in Type 2 Diabetes Patients Treated with Insulin in Real-World Canadian Practice: Protocol for a Prospective Study (Preprint)

2021 ◽  
Author(s):  
Veronique Lambert-Obry ◽  
Jean-Philippe Lafrance ◽  
Michelle Savoie ◽  
Jean Lachaine
Keyword(s):  
Type 2 Diabetes ◽  
Prospective Study ◽  
Real World ◽  
Productivity Loss ◽  
Economic Modeling ◽  
Economic Evaluations ◽  
Productivity Cost ◽  
Productivity Losses ◽  
The Impact

BACKGROUND Type 2 diabetes mellitus (T2DM) imposes a significant burden, with its increasing prevalence and life-threatening complications. In patients not achieving glycemic targets on oral antidiabetic drugs, initiation of insulin is recommended. However, a serious concern about insulin is drug-induced hypoglycemia. Hypoglycemia is known to affect quality of life and healthcare resource utilization. However, health economics and outcomes research (HEOR) data for economic modeling are limited, particularly in terms of utility values and productivity losses. OBJECTIVE The aim of this real-world prospective study is to assess the impact of hypoglycemia on productivity and utility in insulin-treated T2DM adults from Ontario and Quebec (Canada). METHODS This noninterventional, multicenter, 3-month prospective study will recruit patients from four medical clinics and two endocrinology/diabetes clinics. Patients will be identified using appointment lists, and enrolled through consecutive sampling during routinely scheduled consultations. To be eligible, patients must be ≥18 years of age, diagnosed with T2DM, and treated with insulin. Utility and productivity will be collected using the EQ-5D-5L questionnaire and the iMTA Productivity Cost Questionnaire (iPCQ), respectively. Questionnaires will be completed at 4, 8 and 12 weeks after recruitment. Generalized estimating equations (GEE) models will be used to investigate productivity losses and utility decrements associated with incident hypoglycemic events while controlling for individual patient characteristics. A total of 500 patients will be enrolled to ensure precision of HEOR estimates. RESULTS This study is designed to fill a gap in the Canadian evidence on the impact of hypoglycemia on HEOR outcomes. More specifically, it will generate productivity and utility inputs for economic modeling in T2DM. CONCLUSIONS Insulin therapies are expensive, and hypoglycemia is a significant component of economic evaluations. Robust HEOR data may help health technology assessment (HTA) agencies in future reimbursement decision making.

scholarly journals Recruitment, retention, and training of people with type 2 diabetes as diabetes prevention mentors (DPM) to support a healthcare professional-delivered diabetes prevention program: the Norfolk Diabetes Prevention Study (NDPS)

2019 ◽  
Vol 7 (1) ◽  
pp. e000619
Author(s):  
Nikki J Garner ◽  
Melanie Pascale ◽  
Kalman France ◽  
Clare Ferns ◽  
Allan Clark ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Prevention Program ◽  
Diabetes Prevention ◽  
Healthcare Professionals ◽  
Diabetes Management ◽  
Low Cost ◽  
Diabetes Prevention Program ◽  
Lifestyle Interventions ◽  
Effective Prevention

ObjectiveIntensive lifestyle interventions reduce the risk of type 2 diabetes in populations at highest risk, but staffing levels are usually unable to meet the challenge of delivering effective prevention strategies to a very large at-risk population. Training volunteers with existing type 2 diabetes to support healthcare professionals deliver lifestyle interventions is an attractive option.MethodsWe identified 141 973 people at highest risk of diabetes in the East of England, screened 12 778, and randomized 1764 into a suite of type 2 diabetes prevention and screen detected type 2 diabetes management trials. A key element of the program tested the value of volunteers with type 2 diabetes, trained to act as diabetes prevention mentors (DPM) when added to an intervention arm delivered by healthcare professionals trained to support participant lifestyle change.ResultsWe invited 9951 people with type 2 diabetes to become DPM and 427 responded (4.3%). Of these, 356 (83.3%) were interviewed by phone, and of these 131 (36.8%) were interviewed in person. We then appointed 104 of these 131 interviewed applicants (79%) to the role (mean age 62 years, 55% (n=57) male). All DPMs volunteered for a total of 2895 months, and made 6879 telephone calls to 461 randomized participants. Seventy-six (73%) DPMs volunteered for at least 6 months and 66 (73%) for at least 1 year.DiscussionIndividuals with type 2 diabetes can be recruited, trained and retained as DPM in large numbers to support a group-based diabetes prevention program delivered by healthcare professionals. This volunteer model is low cost, and accesses the large type 2 diabetes population that shares a lifestyle experience with the target population. This is an attractive model for supporting diabetes prevention efforts.

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