scholarly journals Evaluation of a Novel Test Paper Strip Method for Detecting Occult Blood in Saliva as a Screening Test for Periodontal Disease.

Author(s):  
Mitsuhiro Ohshima ◽  
Kenji Fujikawa ◽  
Kyoichi Kumagai ◽  
Masataka Idesawa ◽  
Sanae Ezawa ◽  
...  
2018 ◽  
Vol 2018 ◽  
pp. 1-8 ◽  
Author(s):  
Yoshiaki Nomura ◽  
Ayako Okada ◽  
Yoh Tamaki ◽  
Hiroko Miura

Periodontal disease is a common inflammatory disease. It affects about 20–50% of global population in both developed and developing countries. Early detection of slight changes of periodontal tissue plays an important role in prevention of onset and progression of periodontal disease. Hence, there is a need of a screening test to assess periodontal tissue for health check-ups. Salivary levels hemoglobin (Hb) has been proposed to assess the conditions of the inflammation of gingiva. The aim of this systematic review was to evaluate and summarize critically the current evidences for Hb as periodontal screening test. We performed a literature search of report published using PubMed databases. A total of 55 articles were retrieved and 16 were selected. Our review focuses on corelation coefficient with periodontal clinical parameters or sensitivity and specificity. As a result, fourteen studies calculated sensitivity and specificity of Hb. Six studies measured salivary levels hemoglobin at laboratory: three studies used polyclonal antibody reactions and other studies used colorimetric tests. Eight studies used paper strip method: 4 studies used monoclonal antibody reaction and 4 studies used colorimetric tests. Youden’s indexes by antibody reaction were better than those of colorimetric methods. Evidences are described above and further studies are necessary to set the cut off values stratified by gender, age and number of remaining teeth.


1992 ◽  
Vol 13 (1) ◽  
pp. 81-84 ◽  
Author(s):  
Corinne L. Fligner ◽  
Ruth Luthi ◽  
Egle Linkaityte-Weiss ◽  
Vidmantas A. Raisys

2011 ◽  
Vol 23 (8) ◽  
pp. 690-694 ◽  
Author(s):  
Marios Efthymiou ◽  
Patrick B. Allen ◽  
Chatura Jayasekera ◽  
Paul V. Desmond ◽  
Andrew C.F. Taylor

2017 ◽  
Vol 2 (3) ◽  
pp. 1
Author(s):  
Claude Bayingana ◽  
Charles Karangwa ◽  
Jean Kalibushi ◽  
Julien Gashegu

Oral infections can act as the site of origin for dissemination of periodonto-bacteria and their toxins as well as induce inflammatory mechanisms to distant body sites, thus linking periodontal diseases to pre-term delivery of low birth weight (PLBW) infants. Periodontal disease is an infection of the tissues surrounding and supporting the teeth. Researchers showed that between 18 and 50 % of all pre-term deliveries are associated with periodontal disease. Porphyromonasgingivalis, Treponema denticola and Tannerella forsythia are among the subgingival microflora most frequently associated with periodontal disease. The presence of these bacteria can be identified by their ability to hydrolyse BANA. BANA is a rapid and effective diagnostic aid shown to correlate well with the clinical indices used to diagnose periodontal disease. The objective of this study was to investigate the association between the presence of member of the red complex (BANA positive species) in subgingival plaque and pre-term delivery of low birth weight in a Rwandan population. Three clinical indices (PI,GI and PD) were measured for each patient. Plaque sample were collected by inserting a sterile probe into the base of the pocket and this served for the measurement of the BANA enzyme test. The age of the population study was between 18 and 47 years with a mean of 30.8 (± 5.34). Among the 450 women examined, 57.1 % had a PI score of 2, 56.0 % had GI score of 2 and 89.6 % had a PD between 4-6 mm. At a level of 5%, a significant association of p-value=0.000 was found between PI vs BANA, GI vs BANA and PD vs BANA. No significant association (p-value=0.073) was found between BANA and mothers who delivered preterm of low birth weight (PLBW). In conclusion, findings of this study showed that BANA cannot be used for now as screening test for mother at risk for preterm delivery, while waiting for a multicenter study which will help to verify the cause of these discrepancies of results. In the other hand we can recommend BANA to be used as a routine test for the detection of periodontal disease due it strong relationship with clinical indices used to diagnose periodontal disease.


1967 ◽  
Vol 13 (11) ◽  
pp. 941-946 ◽  
Author(s):  
J Fischl ◽  
S Segal ◽  
S Rabiah

Abstract A micromethod is described for the determination of acid and alkaline phosphatases. Phenolphthalein diphosphate is used for substrate and may be prepared by a modified method of Huggins and Taltalay (1). The technics employed are simple, and the results bear a close relationship to units of Bodansky (2, 3). The substrates may be used for the preparation of test paper for a screening test.


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