scholarly journals Evaluation of a Screening Test for Periodontal Disease Using Anti-human Hemoglobin Monoclonal Antibody to Detect Occult Blood in Saliva. Comparison with the Clinical Parameters.

1998 ◽  
Vol 40 (1) ◽  
pp. 111-118 ◽  
Author(s):  
Mitsuhiro Ohshima ◽  
Kenji Fujikawa ◽  
Minoru Ariizumi ◽  
Zaimei Shin ◽  
Kuniharu Suzuki ◽  
...  
Keyword(s):  
Monoclonal Antibody ◽  
Periodontal Disease ◽  
Screening Test ◽  
Occult Blood ◽  
Clinical Parameters ◽  
Human Hemoglobin

scholarly journals Evaluation of a Novel Test Paper Strip Method for Detecting Occult Blood in Saliva as a Screening Test for Periodontal Disease.

2001 ◽  
Vol 43 (4) ◽  
pp. 416-423 ◽  
Author(s):  
Mitsuhiro Ohshima ◽  
Kenji Fujikawa ◽  
Kyoichi Kumagai ◽  
Masataka Idesawa ◽  
Sanae Ezawa ◽  
...  
Keyword(s):  
Periodontal Disease ◽  
Screening Test ◽  
Occult Blood ◽  
Paper Strip ◽  
Test Paper ◽  
Strip Method

scholarly journals Oxidative stress in chronic periodontitis patients with type II diabetes mellitus

2018 ◽  
Vol 12 (02) ◽  
pp. 225-231 ◽  
Author(s):  
Ruby Ramya Vincent ◽  
Devapriya Appukuttan ◽  
Dhayanand John Victor ◽  
Aruna Balasundaram
Keyword(s):  
Oxidative Stress ◽  
Diabetes Mellitus ◽  
Periodontal Disease ◽  
Diabetic Patients ◽  
Clinical Parameters ◽  
Type Ii ◽  
Chronic Periodontal Disease ◽  
Significant Difference ◽  
The Mean ◽  
Group 1

ABSTRACT Objective: Oxidative stress (OS) refers to the disequilibrium between free radicals and antioxidant defense mechanisms and is significantly implicated in the pathogenesis of chronic degenerative and inflammatory diseases such as chronic periodontal disease (CP) and diabetes mellitus (DM). This study aimed to evaluate the total antioxidants capacity (TAOC) and total oxidants status (TOS) in the gingival crevicular fluid (GCF) in CP participants with type II DM. Materials and Methods: A total of 80 participants were allotted into four groups as follows: Group 1: Generalized CP (GCP) without type II DM (n = 20); Group 2: GCP with type II DM (n = 20); Group 3: Type II DM without CP (n = 20); and Group 4: Systemically and periodontally healthy (PH) (n = 20). Clinical parameters such as plaque index, gingival index, probing pocket depth, and clinical attachment level were recorded. Pooled GCF was collected followed by the estimation of TAOC, TOS, and OS index (OSI) using Erel O Colorimetric analysis. Results: The clinical parameters recorded showed the statistically significant difference (P < 0.001) between the groups. The mean TAOC value was the highest in PH group. The mean TOS and OSI were higher in Group 1, 2, and 3 participants when compared to the PH participants. All the biochemical parameters evaluated showed a statistically significant difference (P < 0.001) between groups. Conclusions: The study further validates the use of OSI as a marker for periodontal disease activity and emphasizes the role of OS in the pathogenesis of Type II diabetic patients with the chronic periodontal disease.

scholarly journals Association between markers of cardiovascular risk and clinical parameters of periodontitis

2013 ◽  
Vol 42 (5) ◽  
pp. 336-343 ◽  
Author(s):  
José Eduardo Gomes Domingues ◽  
Mario Vianna Vettore ◽  
Emerson Silva Lima
Keyword(s):  
Cardiovascular Risk ◽  
Periodontal Disease ◽  
Dental Plaque ◽  
Univariate Analysis ◽  
Plasma Concentrations ◽  
Analysis Of Covariance ◽  
High Density Lipoproteins ◽  
Control Group ◽  
Case Group ◽  
Clinical Parameters

INTRODUCTION: Periodontal disease is an inflammatory response to bacteria that reside in the gum tissue and can have systemic repercussion. OBJECTIVE: The aim of this study was to assess the relationship between periodontitis and markers of cardiovascular risk. MATERIAL AND METHOD: Ninety selected patients were assigned into two groups in accordance with their levels of probing pocket depth (PPD) and Clinical Attachment Level (CAL): control group, n= 45 (< 4 sites with PPD ≥ 4.0 mm and CAL ≥ 3.0 mm) and case group, n= 45 (≥ 30% of sites with PPD ≥ 4.0 mm and CAL ≥3.0 mm). Plasma concentrations of C-reactive protein, high sensitive CRP, high-density lipoproteins (HDL-c) and electronegative low density lipoproteins (LDL) were assessed in all participants. Data from medical history and socioeconomic level were also collected from patients. RESULT: Plasma levels of HDL-c were lower in subjects with periodontal disease (p = 0.016) and were inversely associated with the number of sites with PPD ≥ 3 mm (rho= -0.325) and number of sites with PPD ≥ 3 mm and CAL ≥ 3 mm (rho= -0.216). These associations remained significant after adjustments for dental plaque and smoking using Univariate Analysis of Covariance (p < 0.05). Adjusted odds ratio between periodontal disease and levels of HDL-c was 0.94 (CI95% 0.88-0.99) after adjusting for age, smoking and dental plaque. Other investigated markers of cardiovascular risk were not related to periodontal disease. CONCLUSION: Clinical parameters of periodontitis were inversely associated with plasma concentrations of HDL-c.

scholarly journals A Single Course of Anti-CD3 Monoclonal Antibody hOKT3 1(Ala-Ala) Results in Improvement in C-Peptide Responses and Clinical Parameters for at Least 2 Years after Onset of Type 1 Diabetes

Diabetes ◽  
2005 ◽  
Vol 54 (6) ◽  
pp. 1763-1769 ◽  
Author(s):  
K. C. Herold ◽  
S. E. Gitelman ◽  
U. Masharani ◽  
W. Hagopian ◽  
B. Bisikirska ◽  
...  
Keyword(s):  
Monoclonal Antibody ◽  
Type 1 Diabetes ◽  
Clinical Parameters ◽  
C Peptide

scholarly journals Salivary Levels of Hemoglobin for Screening Periodontal Disease: A Systematic Review

2018 ◽  
Vol 2018 ◽  
pp. 1-8 ◽  
Author(s):  
Yoshiaki Nomura ◽  
Ayako Okada ◽  
Yoh Tamaki ◽  
Hiroko Miura
Keyword(s):  
Systematic Review ◽  
Periodontal Disease ◽  
Sensitivity And Specificity ◽  
Screening Test ◽  
Literature Search ◽  
Paper Strip ◽  
Periodontal Tissue ◽  
Antibody Reaction ◽  
Global Population ◽  
Better Than

Periodontal disease is a common inflammatory disease. It affects about 20–50% of global population in both developed and developing countries. Early detection of slight changes of periodontal tissue plays an important role in prevention of onset and progression of periodontal disease. Hence, there is a need of a screening test to assess periodontal tissue for health check-ups. Salivary levels hemoglobin (Hb) has been proposed to assess the conditions of the inflammation of gingiva. The aim of this systematic review was to evaluate and summarize critically the current evidences for Hb as periodontal screening test. We performed a literature search of report published using PubMed databases. A total of 55 articles were retrieved and 16 were selected. Our review focuses on corelation coefficient with periodontal clinical parameters or sensitivity and specificity. As a result, fourteen studies calculated sensitivity and specificity of Hb. Six studies measured salivary levels hemoglobin at laboratory: three studies used polyclonal antibody reactions and other studies used colorimetric tests. Eight studies used paper strip method: 4 studies used monoclonal antibody reaction and 4 studies used colorimetric tests. Youden’s indexes by antibody reaction were better than those of colorimetric methods. Evidences are described above and further studies are necessary to set the cut off values stratified by gender, age and number of remaining teeth.

Value of fecal occult blood test as a screening test before capsule endoscopy

2011 ◽  
Vol 23 (8) ◽  
pp. 690-694 ◽  
Author(s):  
Marios Efthymiou ◽  
Patrick B. Allen ◽  
Chatura Jayasekera ◽  
Paul V. Desmond ◽  
Andrew C.F. Taylor
Keyword(s):  
Capsule Endoscopy ◽  
Screening Test ◽  
Blood Test ◽  
Fecal Occult Blood Test ◽  
Occult Blood ◽  
Fecal Occult Blood ◽  
Occult Blood Test ◽  
Fecal Occult
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