Lymphocyte Subset Analyses in Blood, Spleen and Lymph Nodes of Female Sprague-Dawley Rats after Short or Prolonged Exposure to a 50 Hz 100-μT Magnetic Field

1999 ◽  
Vol 152 (4) ◽  
pp. 436 ◽  
Author(s):  
Susanne Thun-Battersby ◽  
Jürgen Westermann ◽  
Wolfgang Löscher ◽  
Jurgen Westermann ◽  
Wolfgang Loscher
Keyword(s):  
Magnetic Field ◽  
Lymph Nodes ◽  
Prolonged Exposure ◽  
Lymphocyte Subset ◽  
Sprague Dawley ◽  
Sprague Dawley Rats ◽  
Spleen And Lymph Nodes

Prevention of Mammary Tumor Development through Neuroimmunomodulation in the Spleen and Lymph Nodes of Old Female Sprague-Dawley Rats by L-Deprenyl

2013 ◽  
Vol 20 (3) ◽  
pp. 141-151 ◽  
Author(s):  
Srinivasan ThyagaRajan ◽  
Lily Tran ◽  
Christine A. Molinaro ◽  
Daila S. Gridley ◽  
David L. Felten ◽  
...  
Keyword(s):  
Lymph Nodes ◽  
Mammary Tumor ◽  
Tumor Development ◽  
Sprague Dawley ◽  
Sprague Dawley Rats ◽  
Spleen And Lymph Nodes

scholarly journals AN ELECTRON MICROSCOPE STUDY OF LYMPHATIC TISSUE IN RUNT DISEASE

1965 ◽  
Vol 25 (3) ◽  
pp. 149-177 ◽  
Author(s):  
Leon Weiss ◽  
Alan C. Aisenberg
Keyword(s):  
Lymph Nodes ◽  
Plasma Cells ◽  
Cell Types ◽  
Sprague Dawley ◽  
Connective Tissues ◽  
Splenic Cells ◽  
Reticular Cells ◽  
Spleen And Lymph Nodes ◽  
Myelin Figure ◽  
Rats And Mice

The thymus, spleen, and lymph nodes were studied in runt disease induced by a graft of intravenously injected homologous splenic cells into newborn rats and mice. Adult Long-Evans cells (70 x 106) were injected into Sprague-Dawley rats. Adult DBA cells (7 x 106) were injected into C57BL/6 mice. Runted rats were sacrificed at 14 to 28 days of age; mice at 10 to 20 days. The thymic cortex is depleted of small lymphocytes. Those remaining are severely damaged and phagocytized. Evidence of damage includes swelling of mitochondria, myelin figure formation, margination of chromatin, and sharp angulation in nuclear contour. Large numbers of macrophages are present. Epithelial-reticular cells which envelop small cortical blood vessels are often retracted, with the result that the most peripheral layer in the thymic-blood barrier suffers abnormally large gaps. Lymphocytes of the periarterial lymphatic sheaths of spleen and of the cortex of lymph nodes are reduced in number and damaged. Vast numbers of plasma cells and many lymphocytes are evident throughout lymph nodes, in the periarterial lymphatic sheaths, and in the marginal zone and red pulp of the spleen. Plasma cells are of different sizes, the larger having dilated sacs of endoplasmic reticulum. Lymphocytes are small to medium in size. They contain, in varying quantity, ribosomes and smooth membrane-bounded cytoplasmic vesicles approximately 350 to 500 A in diameter. Most plasma cells and lymphocytes are damaged and many of these are phagocytized. Many lymphocytes in lymph nodes, however, show no evidence of damage. Reticular cells and other fixed cells of the connective tissues seldom appear affected. Thus, the major cell types reacting in runt disease are lymphocytes, plasma cells, and histiocytes or macrophages. It appears, therefore, that both the delayed and immediate types of sensitivity play a part in this disease.

Synergism between sinusoidal-50 Hz magnetic field and formaldehyde in triggering carcinogenic effects in male Sprague-Dawley rats

2016 ◽  
Vol 59 (7) ◽  
pp. 509-521 ◽  
Author(s):  
Morando Soffritti ◽  
Eva Tibaldi ◽  
Michela Padovani ◽  
David G. Hoel ◽  
Livio Giuliani ◽  
...  
Keyword(s):  
Magnetic Field ◽  
Sprague Dawley ◽  
Sprague Dawley Rats ◽  
Carcinogenic Effects

The effect of 20-week continuous 60 Hz magnetic field exposure on testicular function in sprague-dawley rats

2018 ◽  
Vol 39 (7) ◽  
pp. 539-546
Author(s):  
Sungman Park ◽  
Young-Jin Kim ◽  
Min Soo Kim ◽  
Hee-Sung Kim ◽  
Min-Woo Kim ◽  
...  
Keyword(s):  
Magnetic Field ◽  
Testicular Function ◽  
Sprague Dawley ◽  
Field Exposure ◽  
Magnetic Field Exposure ◽  
Sprague Dawley Rats

Toxicity bioassay in Sprague-Dawley rats exposed to 20 kHz triangular magnetic field for 90 days

2006 ◽  
Vol 27 (2) ◽  
pp. 105-111 ◽  
Author(s):  
Sung-Ho Kim ◽  
Hae-June Lee ◽  
Soo-Yong Choi ◽  
Youn-Myoung Gimm ◽  
Jeong-Ki Pack ◽  
...  
Keyword(s):  
Magnetic Field ◽  
Sprague Dawley ◽  
Toxicity Bioassay ◽  
Sprague Dawley Rats

Effects of Inhaled Hexachlorobenzene Aerosols on Rat Pulmonary Host Defenses

1989 ◽  
Vol 5 (3) ◽  
pp. 451-461 ◽  
Author(s):  
Robert L. Sherwood ◽  
Peter T. Thomas ◽  
William J. O'shea ◽  
Jeannie N. Bradof ◽  
Helen V. Ratajczak ◽  
...  
Keyword(s):  
Lymph Nodes ◽  
B Cell ◽  
Bactericidal Activity ◽  
Peritoneal Macrophages ◽  
Sprague Dawley ◽  
Mesenteric Lymph Nodes ◽  
Mesenteric Lymph ◽  
Sprague Dawley Rats ◽  
Cell Mitogen

Pulmonary bactericidal activity, macrophage phagocytic activity, alveolar macrophage (AM) enzyme activity, and T- and B-cell mitogenesis of lymphocytes from lung associated lymph nodes (LALN) or mesenteric lymph nodes (MESLN) were assessed in Sprague-Dawley rats exposed 4 hr/d, 4 days/wk for 1, 4, or 16 days to hexachlorobenzene (HCB) aerosols. Pulmonary bactericidal activity was depressed after 1 or 4 but not 16 exposures to 35 mg/m3 of HCB. AM phagocytosis of 51Cr-RBC in vitro was increased after 4 but not 1 or 16 exposures to HCB, and no effect was observed in peritoneal macrophages. HCB significantly enhanced mitogenesis in MESLN to the B-cell mitogen Salmonella typhimurium lipopolysaccharide (STM) after 4 exposures; LALN STM mitogenesis and LALN and MESLN mitogenesis to phytohemagglutinin (PHA) were not affected. After 16 exposures, however, the PHA responses in LALN and MESLN were significantly increased and decreased, respectively.

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