Concurrent Infections with the Ruminant Nematodes Haemonchus contortus and Trichostrongylus colubriformis in Jirds, Meriones unguiculatus, and Use of This Model for Anthelmintic Studies

1991 ◽  
Vol 77 (4) ◽  
pp. 621 ◽  
Author(s):  
G. A. Conder ◽  
S. S. Johnson ◽  
P. M. Guimond ◽  
D. L. Cox ◽  
B. L. Lee
Keyword(s):  
Haemonchus Contortus ◽  
Meriones Unguiculatus ◽  
Trichostrongylus Colubriformis ◽  
Concurrent Infections

Evaluation of broad-spectrum anthelmintic activity in a novel assay against Haemonchus contortus, Trichostrongylus colubriformis and T. sigmodontis in the gerbil Meriones unguiculatus

2006 ◽  
Vol 80 (4) ◽  
pp. 393-396 ◽  
Author(s):  
D.A. Ostlind ◽  
S. Cifelli ◽  
W.G. Mickle ◽  
S.K. Smith ◽  
D.V. Ewanciw ◽  
...  
Keyword(s):  
Gastrointestinal Tract ◽  
Natural Product ◽  
Broad Spectrum ◽  
Haemonchus Contortus ◽  
Macrocyclic Lactone ◽  
Anthelmintic Activity ◽  
Meriones Unguiculatus ◽  
Trichostrongylus Colubriformis ◽  
Separate Part ◽  
Laboratory Assay

AbstractThe gerbil Meriones unguiculatus, infected with three species of nematodes, each located in a separate part of the gastrointestinal tract, provided a reliable laboratory assay for the evaluation of broad-spectrum anthelmintic activity. Gerbils harbouring 6-day-old infections of Haemonchus contortus, Trichostrongylus colubriformis and T. sigmodontis were given selected broad-spectrum anthelmintics by gavage. Three benzimidazoles, thiabendazole, oxfendazole and albendazole, a tetrahydropyrimidine, morantel, an imidazothiazole, levamisole hydrochloride, a macrocyclic lactone, ivermectin and an experimental natural product, paraherquamide, were active against all three nematodes at various dosages. Trichostrongylus colubriformis was most sensitive to levamisole hydrochloride, morantel, thiabendazole and paraherquamide whereas ivermectin, oxfendazole and albendazole were more effective against H. contortus. All compounds were active against the caecal nematode T. sigmodontis although it was less sensitive than T. colubriformis. Haemonchus contortus was more sensitive than T. sigmodontis to all anthelmintics tested except thiabendazole.

Effects of artemisinin and Artemisia extracts on Haemonchus contortus in gerbils (Meriones unguiculatus)

2011 ◽  
Vol 175 (1-2) ◽  
pp. 103-108 ◽  
Author(s):  
Jill M. Squires ◽  
Jorge F.S. Ferreira ◽  
David S. Lindsay ◽  
Anne M. Zajac
Keyword(s):  
Haemonchus Contortus ◽  
Meriones Unguiculatus

Studies on resistance of sheep to infestation with Haemonchus contortus and Trichostrongylus spp. and on the immunological reactions of sheep exposed to infestation. VI. The influence of age and nutrition on resistance to Trichostrongylus colubriformis.

1953 ◽  
Vol 4 (3) ◽  
pp. 340 ◽  
Author(s):  
DF Stewart ◽  
HMcL Gordon
Keyword(s):  
Haemonchus Contortus ◽  
High Protein Diet ◽  
High Protein ◽  
Protein Diet ◽  
Previous Exposure ◽  
Trichostrongylus Colubriformis ◽  
The Poor ◽  
Experimental Infestation ◽  
Immunological Reactions ◽  
Striking Contrast

Of 10 sheep aged 3-4 years which had been born and maintained under worm-free conditions, 7 died from an initial experimental infestation with Trichostrongylus colubriformis. This mortality was in striking contrast to the results with nine-months-old sheep which had had previous experience of infestation. It demonstrated that resistance to T. colubriformis could not be ascribed to increasing age. In a group fed on a low plane of nutrition and given 40,000 or 100,000 T. colubriformis larvae, more sheep developed infestations than did similar sheep in groups given an adequate or a high-protein diet. in lambs which had been kept worm-free since birth and then dosed with 20,000 T. colubriformis larvae, infestation developed almost equally in those fed on the poor diet and those fed on the high-protein diet. The groups fed on the low plane of nutrition successfully withstood subsequent challenge doses of up to 300,000 T. colubriformis larvae. In these experiments, previous exposure to infestation apparently exercised more influence on resistance than did diet.

scholarly journals Ellagitannins Inhibit the Exsheathment of Haemonchus contortus and Trichostrongylus colubriformis Larvae: The Efficiency Increases Together with the Molecular Size

2020 ◽  
Vol 68 (14) ◽  
pp. 4176-4186 ◽  
Author(s):  
Maarit Karonen ◽  
Jeffrey R. Ahern ◽  
Lucie Legroux ◽  
Jussi Suvanto ◽  
Marica T. Engström ◽  
...  
Keyword(s):  
Haemonchus Contortus ◽  
Molecular Size ◽  
Trichostrongylus Colubriformis

scholarly journals Interaction between abomasal blood feeder Haemonchus contortus and intestinal mucosal browser Trichostrongylus colubriformis during co-infection in Boer goats

2020 ◽  
Vol 287 ◽  
pp. 109274
Author(s):  
N. Hayyan Basripuzi ◽  
Reuben S.K. Sharma ◽  
Z. Norhadila ◽  
Z.S. Shahar ◽  
M.S. Nor-Dilaila ◽  
...  
Keyword(s):  
Haemonchus Contortus ◽  
Trichostrongylus Colubriformis ◽  
Boer Goats
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