Patents: Monopolies: Contributory Infringement of Process Patent

1938 ◽  
Vol 36 (7) ◽  
pp. 1214
Author(s):  
Julian Caplan
Antioxidants ◽  
2021 ◽  
Vol 10 (3) ◽  
pp. 418
Author(s):  
Paolo Morazzoni ◽  
Paola Vanzani ◽  
Sandro Santinello ◽  
Antonina Gucciardi ◽  
Lucio Zennaro ◽  
...  

A “green” solvent-free industrial process (patent pending) is here described for a grape seed extract (GSE) preparation (Ecovitis™) obtained from selected seeds of Veneto region wineries, in the northeast of Italy, by water and selective tangential flow filtration at different porosity. Since a comprehensive, non-ambiguous characterization of GSE is still a difficult task, we resorted to using an integrated combination of gel permeation chromatography (GPC) and electrospray ionization high resolution mass spectrometry (ESI-HRMS). By calibration of retention time and spectroscopic quantification of catechin as chromophore, we succeeded in quantifying GPC polymers up to traces at n = 30. The MS analysis carried out by the ESI-HRMS method by direct-infusion allows the detection of more than 70 species, at different polymerization and galloylation, up to n = 13. This sensitivity took advantage of the nanoscale shotgun approach, although paying the limit of missed separation of stereoisomers. GPC and MS approaches were remarkably well cross-validated by overlapping results. This simple integrated analytical approach has been used for quality control of the production of Ecovitis™. The emerging feature of Ecovitis™ vs. a popular benchmark in the market, produced by a different technology, is the much lower content of species at low n and the corresponding increase of species at high n.


Nature ◽  
1993 ◽  
Vol 364 (6435) ◽  
pp. 274-274
Author(s):  
Diane Gershon
Keyword(s):  

1898 ◽  
Vol 12 (1) ◽  
pp. 35 ◽  
Author(s):  
Odin B. Roberts

2017 ◽  
Vol 21 (7) ◽  
pp. 956-965
Author(s):  
Anthony D. Sabatelli ◽  
Ann Pearson ◽  
John P. Jasper

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