Cruel Hand of Bilski: Culminating the Shortsighted Crusade for Marginalization of the 'Process' Patent

2009 ◽  
Author(s):  
Christopher Abernethy
Keyword(s):  
Antioxidants ◽  
2021 ◽  
Vol 10 (3) ◽  
pp. 418
Author(s):  
Paolo Morazzoni ◽  
Paola Vanzani ◽  
Sandro Santinello ◽  
Antonina Gucciardi ◽  
Lucio Zennaro ◽  
...  

A “green” solvent-free industrial process (patent pending) is here described for a grape seed extract (GSE) preparation (Ecovitis™) obtained from selected seeds of Veneto region wineries, in the northeast of Italy, by water and selective tangential flow filtration at different porosity. Since a comprehensive, non-ambiguous characterization of GSE is still a difficult task, we resorted to using an integrated combination of gel permeation chromatography (GPC) and electrospray ionization high resolution mass spectrometry (ESI-HRMS). By calibration of retention time and spectroscopic quantification of catechin as chromophore, we succeeded in quantifying GPC polymers up to traces at n = 30. The MS analysis carried out by the ESI-HRMS method by direct-infusion allows the detection of more than 70 species, at different polymerization and galloylation, up to n = 13. This sensitivity took advantage of the nanoscale shotgun approach, although paying the limit of missed separation of stereoisomers. GPC and MS approaches were remarkably well cross-validated by overlapping results. This simple integrated analytical approach has been used for quality control of the production of Ecovitis™. The emerging feature of Ecovitis™ vs. a popular benchmark in the market, produced by a different technology, is the much lower content of species at low n and the corresponding increase of species at high n.


Nature ◽  
1993 ◽  
Vol 364 (6435) ◽  
pp. 274-274
Author(s):  
Diane Gershon
Keyword(s):  

2017 ◽  
Vol 21 (7) ◽  
pp. 956-965
Author(s):  
Anthony D. Sabatelli ◽  
Ann Pearson ◽  
John P. Jasper

2017 ◽  
Vol 23 (1) ◽  
pp. 51
Author(s):  
Mario Ricardo De La Cruz Azabache ◽  
Dionicio Adolfo Marcelo Astocóndor

El presente proyecto de investigación aplicada; tiene como objetivo definir las especificaciones técnicas de un producto de bandera como es el pisco peruano. La importancia de esta investigación, radica en el hecho que por ser la producción de pisco en el Perú mayormente artesanal y de poca tecnología, ésta no garantiza niveles estándar de calidad, composición y producción. Este trabajo contempla asimismo la obtención de un proceso estándar para la elaboración de aguardiente de uvas denominado Pisco, con pruebas de investigación a nivel de Reactor Prototipo, el desarrollo de producto a nivel comercial denominado Pisco UNI y la obtención de una Patente de Invención. Los resultados obtenidos a través de un trabajo multidisciplinario; con participación de investigadores y empresarios de instituciones como la Facultad de Ciencias Biológicas de la Universidad Nacional de San Marcos; UNMSM; el Centro de Innovación de la Vid; CITEvid y Bodega y Viñedos La Caravedo de Ica, fueron satisfactorios, obteniéndose un proceso estándar que garantiza la elaboración de un producto de calidad y protegido además con una Patente de Invención. Asimismo, el proyecto tuvo como objetivo suministrar herramientas de innovación tecnológica a los estudiantes de la Facultad de Ingeniería Química y Textil de la UNI; FIQT, a fin que puedan aplicarlos en el desarrollo de su carrera o en la creación de su propia empresa o fuente de trabajo, como una alternativa de desarrollo luego que egresen de la universidad. Palabras clave.-Investigación aplicada, Pisco Peruano. Aguardiente de uvas, Reactor prototipo, Multidisciplinario, Proceso estándar, Patente de Invención. ABSTRACTThe present project in Applied Research has the objective to define the technical specifications of Peruvian Pisco, a traditional drink and patrimony, symbol of Peruvian pride and nationality. The importance of this project lies in the search for a higher standard of quality, composition and production for pisco elaboration in Peru, which is mostly artisanal and low technology. This design also involves obtaining a standardized process for elaboration of the grape liqueur denominated Pisco, with research trials at Prototype Reactor level, the development of a commercial product named Pisco UNI and obtaining an Invention Patent. Through a multidisciplinary group with the participation of professionals from the Facultad de Ciencias Biológicas de la Universidad Nacional de San Marcos; UNMSM; the Centro de Innovación de la Vid; CITEvid and Bodega y Viñedos La Caravedo de Ica; the obtained results were satisfactory, the standardized process guaranties the elaboration of a product of high quality and protected by an Invention Patent. The project also aims to provide technological innovation tools to students from Facultad de Ingeniería Química y Textil de la UNI; FIQT, that they can apply in their career development or creating their own business or work source, as a development alternative after they graduate. Keywords.-Applied research, Peruvian Pisco, Grape liqueur, Prototype reactor, Multi- disciplinary, Standard process, Patent of invention.


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