scholarly journals The significance of resistin concentration in metabolical diseases

2010 ◽  
Vol 67 (12) ◽  
pp. 965-968
Author(s):  
Dragisa Rasic ◽  
Radojica Stolic ◽  
Aleksandar Jovanovic ◽  
Goran Trajkovic ◽  
Julijana Rasic ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Renal Failure ◽  
Waist Circumference ◽  
Renal Insufficiency ◽  
Biochemical Analysis ◽  
Metabolic Diseases ◽  
Arterial Blood ◽  
Significant Difference ◽  
Patients With Diabetes ◽  
Active Substances

Background/Aim. Adipose tissue secrets a number of hormonal active substances that play an important role in the development of various metabolic diseases. The aim of this study was to determine the resistin significance in patients with various forms of metabolic diseases. Methods. The survey was conducted in a hospital in Laplje Selo, and included 102 patients suffering from diabetes mellitus, cardiovascular disease and renal insufficiency. All patients were verified and anthropometric characteristics and the basic hematological and biochemical analysis and resistin level were controlled. Results. The average age of the patients, 69 (67.6%) men and 33 (32.4%) women, was 55 ? 9.3 years. It was about two-thirds of smokers. The values of mean arterial blood pressure suggested that our patients had expressed hypertension, body mass index (28.5 ? 3.4 kg/m2) pointed to excessive well-fed, the circumference of hips (100 ? 10.8 cm), waist circumference (110 ? 17.4 cm) and the ratio of hip/waist circumference (1.05 ? 0.14) indicated a significant intra-abdominal distribution of fat tissue. More than one third of our patients had a certain form of cardiovascular diseases, renal failure was present almost in a fifth of patients, while diabetes mellitus was verified in 44.1% of the studied population. Significantly higher values of resistin concentrations were determined in patients with renal insufficiency and diabetes mellitus. In relation to the level of resistin, according to the number of metabolic diseases per patient, a statistically significant difference was achieved (F = 11.80, DF = 4.61, p < 0.001). Spearman correlation (r = 0.66, p < 0.001) found a statistically significant correlation between the number of diseases in one subject and the levels of resistin. Conclusion. In patients with diabetes mellitus and renal failure higher concentrations of resistin were recorded.

Biochemical Analysis of Vitreous Humor in Postmortal Diagnosis of Renal Failure

10.12737/2726 ◽  
2013 ◽  
Vol 20 (4) ◽  
pp. 47-49
Author(s):  
Терёхина ◽  
N. Terekhina ◽  
Акимов ◽  
Pavel Akimov
Keyword(s):  
Diabetes Mellitus ◽  
Molecular Weight ◽  
Renal Failure ◽  
Serum Creatinine ◽  
Biochemical Analysis ◽  
Vitreous Humor ◽  
Control Group ◽  
Patients With Diabetes ◽  
Maximum Content

The content of medium molecular weight peptides and creatinine in serum and vitreous humor from 48 corpses of people suffering from diabetes mellitus during his lifetime and 27 without this disease, formed the control group, were investigated. The presence of renal failure among patients with diabetes mellitus and in the control group was, respectively, in 20 and 15 persons was revealed. The content of serum creatinine in cadaver blood without renal failure was more than 2-2,5 - folds in comparative with living people and was not more than 240 μηΊθΙ/L. The content of serum medium molecular weight peptides in control group was not more than 2,8 g/L, and in the group of diabetes mellitus without renal failure - 2,9 g/L. The obtained results are analogical with data of living people accordingly literature sources. Direct correlation between the content of creatinine, medium molecular weight peptides and vitreous humor and serum are estimated. The maximum content of creatinine and medium molecular weight peptides in vitreous humor were, respectively, 110 μΓηοΙ/L and 0,5 g/L. The values extreme graduated in presents of renal failure as in serum, as in vitreous humor. Thus, in postmortal period appropriate to determine the vitreous humor creatinine and medium molecular weight peptides content for the diagnosis of renal failure.

scholarly journals Differences in Arteriovenous Fistula Maturation between Diabetes Mellitus and Non-Diabetes Mellitus in Chronic Renal Failure Patients in Padang

2021 ◽  
Vol 6 (1) ◽  
pp. 1287-1291
Author(s):  
Richard Santosa ◽  
Raflis Rustam ◽  
Vendry Rivaldy
Keyword(s):  
Diabetes Mellitus ◽  
Renal Failure ◽  
Chronic Renal Failure ◽  
Arteriovenous Fistula ◽  
Kidney Failure ◽  
Chronic Kidney Failure ◽  
Fistula Surgery ◽  
Arteriovenous Fistulas ◽  
Significant Difference ◽  
Patients With Diabetes

Background: Arteriovenous fistula (AVF) is the preferred vascular access for hemodialysis (HD). Several factors can affect AVF maturity, such as diabetes. This study aims to determine the differences in the maturation of arteriovenous fistulas between diabetes mellitus and non-diabetes mellitus in patients with chronic kidney failure in Padang. Methods: This was a comparative cross-sectional study of patients with chronic kidney failure who underwent arteriovenous fistula surgery in Padang. The sampling technique in this study was consecutive sampling. The analysis was carried out using statistical analysis according to the existing data scale and using SPSS software. Results: This study involved 46 patients with chronic kidney failure who underwent arteriovenous fistula surgery in Padang, of which 23 patients with diabetes mellitus and 23 patients with non-diabetes mellitus. The diameter of the arteriovenous fistula between diabetes mellitus and non-diabetes mellitus in patients with chronic renal failure had a significant difference (p<0.05). There was no significant difference in flow, depth, and maturation of arteriovenous fistulas in patients with diabetes mellitus and non-diabetes mellitus with chronic renal failure. Conclusion: There is no difference in the maturation of arteriovenous fistula between patients with diabetes mellitus and non-diabetes mellitus

Contrast Material-Induced Renal Failure in Patients with Diabetes Mellitus, Renal Insufficiency, or Both

1989 ◽  
Vol 3 (2) ◽  
pp. 181 ◽  
Author(s):  
P. S. PARFREY ◽  
S. M. GRIFFITHS ◽  
B. J. BARRETT ◽  
M. D. PAUL ◽  
M. GENGE ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Renal Failure ◽  
Renal Insufficiency ◽  
Contrast Material ◽  
Patients With Diabetes

Contrast Material-Induced Renal Failure in Patients with Diabetes Mellitus, Renal Insufficiency, or Both

1989 ◽  
Vol 320 (3) ◽  
pp. 143-149 ◽  
Author(s):  
Patrick S. Parfrey ◽  
Sheila M. Griffiths ◽  
Brendan J. Barrett ◽  
Michael D. Paul ◽  
Margot Genge ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Renal Failure ◽  
Renal Insufficiency ◽  
Contrast Material ◽  
Patients With Diabetes

GAMBARAN PENYAKIT PERIODONTAL PADA PENDERITA DIABETES MELITUS DI RUMAH SAKIT UMUM PUSAT PROF. DR. R. D KANDOU MANADO

e-GIGI ◽  
2015 ◽  
Vol 3 (2) ◽  
Author(s):  
Ezra G. R. Tambunan ◽  
Karel Pandelaki ◽  
Christy N. Mintjelungan
Keyword(s):  
Diabetes Mellitus ◽  
Periodontal Disease ◽  
Metabolic Diseases ◽  
Age Groups ◽  
Evaluation Criteria ◽  
Sampling Technique ◽  
Oral Health Problem ◽  
Result Show ◽  
Patients With Diabetes ◽  
Diabetes Melitus

Abstract: Diabetes mellitus (DM) is a group of metabolic diseases with characteristic hyperglycemia that occurs due to insulin secretion, insulin action or both. This disease affects many societies and continuously growing in Indonesia. Periodontal disease is an oral health problem which has a relatively high prevalence in the community where periodontal disease in all age groups in Indonesia.The purpose of this study was to determine the periodontal disease in patients with diabetesmellitus in RSUP Prof. dr. R. D. Kandou Manado. This descriptive study has 68 sample taken with total sampling technique. The sample is examined using evaluation criteria gingival index and CPITN index. The result show that subjects with periodontitis with a score of 4 is the highest as many as 18 people (44%) and subject with a score of 2 is that at least as many as 8 people (19.5%). And subjects with bad gingivitis is the highest as many as 10 people (52.6%) and subject with the good gingivitis is the at least as many as 5 people (26.3%). Based on the result of this study, periodontal disease in patients with diabetes mellitus in RSUP Prof. Dr. R. D. Kandou most that periodontitis with the number of 41 people (68.3%) compared to gingivitis which is just as many as 19 people (31.7%)Keywords: diabetes mellitus, periodontitis, gingivitis, periodontalAbstrak:Diabetes Melitus (DM) merupakan suatu kelompok penyakit metabolik dengan karakteristik hiperglikemia yang terjadi karena sekresi insulin, kerja insulin atau kedua-duanya. Penyakit ini merupakan penyakit yang banyak diderita kalangan masyarakat dan terus berkembang di Indonesia. Penyakit periodontal merupakan masalah kesehatan gigi dan mulut yang memiliki prevalensi cukup tinggi di masyarakat dimana penyakit periodontal pada semua kelompok umur di Indonesia.Tujuan penelitian ini adalah untuk mengetahui penyakit periodontal pada penderita diabetes mellitus di RSUP Prof. dr. R. D. Kandou Manado. Jenis penelitian ini adalah penelitian deskriptif dengan jumlah sampel 60 orang yang diambil dengan teknik total sampling. Sampel diperiksa dengan menggunakan kriteria penilaian indeks gingiva dan indeks CPITN. Hasil menunjukkan bahwa yang mengalami periodontitis dengan skor 4 adalah yang paling tinggi yaitu sebanyak 18 orang (44%), dan subjek yang mengalami skor 2 adalah yang yang paling sedikit yaitu sebanyak 8 orang (19.5%). Sedangkan yang mengalami gingivitis yang paling tinggi yaitu gingivitis buruk sebanyak 10 orang (52.6%) dan yang paling sedikit adalah yang mengalami gingivitis ringan yaitu sebanyak 5 orang (26.3%). Berdasarkan hasil penelitian ini dapat disimpulkan bahwa penyakit periodontal yang paling banyak ditemui pada penderita diabetes melitus di RSUP Prof. Dr. R. D. Kandou Manado adalah penyakit periodontitis yaitu sebanyak 41 orang (68.3%) dan yang paling sedikit adalah gingivitis yaitu sebanyak 19 orang (31.7%)Kata kunci: diabetes melitus, periodontitis, gingivitis, periodontal

scholarly journals Hand osteomyelitis in arterial calcification, diabetes mellitus and end-stage renal failure: a comparison of 210 cases over 12 years

2021 ◽  
pp. 175319342098187
Author(s):  
Matthew Wyman ◽  
Dallan Dargan ◽  
Jennifer Caddick ◽  
Victoria Giblin
Keyword(s):  
Diabetes Mellitus ◽  
Renal Failure ◽  
Disease Free Survival ◽  
Arterial Calcification ◽  
Level Of Evidence ◽  
Free Survival ◽  
End Stage Renal Failure ◽  
Patients With Diabetes ◽  
End Stage ◽  
Steal Syndrome

We present 210 patients with hand osteomyelitis in 246 rays over 12 years, including detailed analysis of 29 patients in this cohort with digital artery calcification evident on plain X-ray. Overall 71 patients had diabetes mellitus and/or end-stage renal failure, including 28 of 29 patients with calcification. In the calcification group, 17 patients had ipsilateral arteriovenous fistulae, five had steal syndrome and 15 had digital ulceration or skin necrosis. Compared with 181 controls, patients with calcification had more affected bones, polymicrobial infections, surgical procedures, phalanges and digits amputated and had higher mortality at 1 year (12 of 29) and 5 years (20 of 29), as a result of comorbidities. Absence of calcification in 43 patients with diabetes and/or end-stage renal failure was associated with better outcomes on all the above parameters. Early amputation to maximize disease-free survival may be appropriate for patients with hand osteomyelitis and arterial calcification. Level of evidence: IV

scholarly journals The Relationship between Frequently Used Glucose-Lowering Agents and Gut Microbiota in Type 2 Diabetes Mellitus

2018 ◽  
Vol 2018 ◽  
pp. 1-7 ◽  
Author(s):  
You Lv ◽  
Xue Zhao ◽  
Weiying Guo ◽  
Ying Gao ◽  
Shuo Yang ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Gut Microbiota ◽  
Metabolic Diseases ◽  
Short Chain Fatty Acids ◽  
Current Evidence ◽  
Diabetic Patients ◽  
Glucose Lowering ◽  
Patients With Diabetes ◽  
Gastrointestinal Side Effects ◽  
Underlying Mechanisms

Metabolic diseases, especially diabetes mellitus, have become global health issues. The etiology of diabetes mellitus can be attributed to genetic and/or environmental factors. Current evidence suggests the association of gut microbiota with metabolic diseases. However, the effects of glucose-lowering agents on gut microbiota are poorly understood. Several studies revealed that these agents affect the composition and diversity of gut microbiota and consequently improve glucose metabolism and energy balance. Possible underlying mechanisms include affecting gene expression, lowering levels of inflammatory cytokines, and regulating the production of short-chain fatty acids. In addition, gut microbiota may alleviate adverse effects caused by glucose-lowering agents, and this can be especially beneficial in diabetic patients who experience severe gastrointestinal side effects and have to discontinue these agents. In conclusion, gut microbiota may provide a novel viewpoint for the treatment of patients with diabetes mellitus.

scholarly journals EFFECT OF FAMILY PSYCHOEDUCATION ON CAREGIVER SUPPORT IN THE TREATMENT OF PATIENTS WITH TYPE II DIABETES MELLITUS

2018 ◽  
Vol 4 (1) ◽  
pp. 112-119
Author(s):  
Andika Siswoaribowo ◽  
Mateus Sakundarno ◽  
Muhammad Mu’in
Keyword(s):  
Diabetes Mellitus ◽  
T Test ◽  
Control Group ◽  
P Value ◽  
Family Psychoeducation ◽  
Control Group Design ◽  
Caregiver Support ◽  
Significant Difference ◽  
Patients With Diabetes ◽  
And Control

Background: Diabetes Mellitus is a chronic disease that requires treatment for long periods of time so it can cause physical and psychological problems for sufferers and families (caregiver). Caregiver's role is expected to provide support for people with diabetes mellitus. Family psychoeducation is a strategy that can be applied for caregiver in overcoming problems that arise during the treatment of patients with diabetes mellitus.Objective: This study aims to determine the effect of family psychoeducation on caregiver support in the treatment of patients with diabetes mellitus type II.Methods: This research used a quasi experiment with  pre-test post-test control group design. A total of 46 caregivers and patients with diabetes mellitus were recruited puposively, with 23 respondents assigned in the experiment and control group. Caregiver support scale was used to measure caregiver support, and Hensarling Diabetes Family Support Scale (HDFSS) for measuring perception of patients toward the treatment of caregiver.  Data were analyzed using paired t-test and independent t-test. Results: Findings showed there was an increase of caregiver knowledge from 5.39 to 9.09 and an improvement of caregiver treatment from 40.30 to 67.04 after given family psychoeducation. There was a significant difference of caregiver support in the experimental and control group with p-value <0.001 (<0.05).Conclusion: Family psychoeducation can increase caregiver support in the treatment of diabetes mellitus patients. The intervention can be one of nurses interventions in the empowerment of family in improving the treatment of chronic diseases, particularly in diabetes mellitus.

scholarly journals BSMI AND TAQI POLYMORPHISMS IN VITAMIN D RECEPTOR GENE OF TYPE 2 DIABETES MELLITUS PATIENTS FROM NORTH INDIA

2016 ◽  
Vol 9 (9) ◽  
pp. 186 ◽  
Author(s):  
Nancy Taneja ◽  
Rajesh Khadagawat ◽  
Shalini Mani
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Vitamin D ◽  
Vitamin D Receptor ◽  
Metabolic Diseases ◽  
Fragment Length Polymorphism ◽  
Wild Type ◽  
Significant Difference ◽  
Restriction Fragment Length

ABSTRACTObjective: Polymorphisms in vitamin D receptor (VDR) genes are known to be linked with different metabolic diseases including Type 2 diabetesmellitus (T2DM) also. However, the association of these polymorphisms is not much explored for the Indian population. To determine the prevalenceof BsmI and TaqI polymorphism in VDR gene of T2DM patients from North India.Methods: Blood samples were obtained from 100 well-characterized T2DM patients and 100 healthy controls. Genomic DNA was isolated from bloodsamples and using polymerase chain reaction/restriction fragment length polymorphism based method, the presence of these polymorphisms wasinvestigated in these samples. The data were statistically analyzed using SPSS 21.0 software.Results: For TaqI polymorphism, both the wild type (TT) and heterozygous (TC) genotype showed a significant difference between patients andcontrols (p=0.023 and p<0.001, respectively). Whereas, the frequency of CC genotype was not significantly different among these groups (p=0.506).For BsmI polymorphism also, the frequency of wild type (GG) and heterozygous (GA) genotype was significantly different in patients and controls(p=0.027 and p=0.001), respectively. However, the frequency of AA genotype was not of statistical significance in patients (p=0.071).Conclusions: The mutant alleles of TaqI and BsmI polymorphisms are known to be associated with different metabolic diseases, including diabetestoo. In our study also, there is a significant difference between the frequency of wild type and heterozygous genotype for these polymorphisms. Thissuggests that BsmI and TaqI polymorphisms may be associated with T2DM patients.Keywords: Type 2 diabetes mellitus, Polymorphism, Vitamin D receptor, Patient, Control, Restriction fragment length polymorphism.

scholarly journals The Prevalence of Giardia Intestinalis in Dyspeptic and Diabetic Patients

2011 ◽  
Vol 2011 ◽  
pp. 1-4 ◽  
Author(s):  
Gözde Derviş Hakim ◽  
Şafak Kızıltaş ◽  
Hilmi Çiftçi ◽  
Şafak Göktaş ◽  
İlyas Tuncer
Keyword(s):  
Diabetes Mellitus ◽  
Giardia Intestinalis ◽  
Diabetic Patients ◽  
Elisa Method ◽  
Number Of Patients ◽  
Significant Difference ◽  
Patients With Diabetes ◽  
Stool Specimens ◽  
Positive Results ◽  
Healthy Persons

Background and Aims. We aimed to investigate the prevalence of Giardiasis in patients with dyspepsia and patients with diabetes mellitus. Methods. 400 patients and 100 healthy persons were included in this clinical prospective study. The number of patients in each group was equal, 200 dyspeptic and 200 diabetic, respectively. The antigen of G. lntestinalis was determined in the stool specimens by ELISA method. Results. The frequency of Giardiasis was 7% in dyspeptic and 15% in diabetic patients. There was no positive results in any of the healthy persons. There was a significant difference in prevalence rate of Giardiasis between patients with dyspepsia and diabetes mellitus (P<0.05). Conclusions. These results revealed that the prevalence of Giardiasis in dyspepsia and with diabetes mellitus was high in our country. This is the first study investigating the prevalence of Giardiasis in diabetic patients. To investigate Giardiasis in diabetic patients, who have dyspepsia or not, may be a good approach for public health.

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