scholarly journals PHYTOCHEMISTRY STUDY OF PLANTS BELONGING TO CAPPARIS

2020 ◽  
Author(s):  
Jamal A.N. Al-Mahweety ◽  
Ali Alyahawi
Keyword(s):  
Peer Review ◽  
Bioactive Molecules ◽  
Mentha Piperita ◽  
Medicinal Uses ◽  
Spectral Techniques ◽  
Soxhlet Apparatus ◽  
Pure Compounds ◽  
Review Reports ◽  
First Time ◽  
E Mail

Objectives:  Bioactive molecules have gained attention in recent time due to their diverse effects and their economic importance. The objective of current study was to isolate, analyze and identify the active constituents from leaves of C.   cartilaginea. Methods:  The powdered leaves were extracted with different solvents by using Soxhlet apparatus and carried out by different chromatographic techniques. The phytochemical characterizations were evaluated by nuclear magnetic resonance and mass spectrometry. Results:  Three pure compounds were identified representing 1.6% of the total phytochemical composition. Yield of compounds 1, is Kaempferol  (6gm), compound 2, is Dihydroxy-lup-20(29)-en-28-oic acid (3.8gm) and compound 3, is β-Sitosterol (5gm). Three of them are report for first time from this Spp.  Conclusion:  From this study, can be concluded that report for the first time from C. cartilaginea leaves, identified 3 pure chemical compounds, by analysis using various physical and spectral techniques. Peer Review History: Received 7 April 2019; Revised 20 April; Accepted 5 May, Available online 15 May 2020 UJPR follows the most transparent and toughest ‘Advanced OPEN peer review’ system. The identity of the authors and, reviewers will be known to each other. This transparent process will help to eradicate any possible malicious/purposeful interference by any person (publishing staff, reviewer, editor, author, etc) during peer review. As a result of this unique system, all reviewers will get their due recognition and respect, once their names are published in the papers. We expect that, by publishing peer review reports with published papers, will be helpful to many authors for drafting their article according to the specifications. Auhors will remove any error of their article and they will improve their article(s) according to the previous reports displayed with published article(s). The main purpose of it is ‘to improve the quality of a candidate manuscript’. Our reviewers check the ‘strength and weakness of a manuscript honestly’. There will increase in the perfection, and transparency. Received file Average Peer review marks at initial stage: 5.0/10 Average Peer review marks at publication stage: 7.0/10 Reviewer(s) detail: Name: Ahmad Najib Affiliation: Universitas Muslim Indonesia, Makassar, Indonesia E-mail: [email protected]   Name: Dr. Ali Gamal Ahmed Al-kaf Affiliation: Sana'a university, Yemen E-mail: [email protected] Comments of reviewer(s): Similar Articles: A STUDY ON DIFFERENT PLANTS OF APOCYNACEAE FAMILY AND THEIR MEDICINAL USES A REVIEW ON MEDICINAL USES OF DIFFERENT PLANTS OF EUPHORBIACEAE FAMILY MENTHA PIPERITA L. - A PROMISING DENTAL CARE HERB MAINLY AGAINST CARIOGENIC BACTERIA ETHNOBOTANY, PHYTOCHEMISTRY AND PHARMACOLOGY OF OCHNA SCHWEINFURTHIANA: A REVIEW

scholarly journals A STUDY OF PHYTOCHEMICAL CONSTITUENTS IN CARALLUMA QUADRANGULA

2020 ◽  
Author(s):  
Jamal A. N. Al-Mahweety ◽  
Sadeq HS Azzam ◽  
Ali Alyahawi
Keyword(s):  
Peer Review ◽  
Folk Medicine ◽  
Chemical Components ◽  
Phytochemical Analysis ◽  
Medicinal Uses ◽  
Initial Stage ◽  
Unique System ◽  
Review Reports ◽  
First Time ◽  
E Mail

Objectives:  Caralluma belongs to the family Asclepiadaceae, native to the Indian sub-continent have different medicinal properties and used in folk medicine as remedies to treat wide variety of diseases and health conditions. Objective of present study was to isolate, analyze and identify the phytochemicals composition from steam of Caralluma  quadrangula. Methods:  Extractions of the chemical components was carried out by different chromatographic techniques. The phytochemical characterizations were evaluated by nuclear magnetic resonance and mass spectrometry. Results:  The quantitative phytochemical analysis of this species exhibited the presence of three compounds, Glochidonol (5gm), Dihydroxy-14-pregn-5-en-20-one (9.8gm), Hydroxystigmast-5-en-7-one (7.8gm) and Stigmasterol (5.7 mg). Hydroxystigmast-5-en-7-one, report from Caralluma  quadrangula stem as first time.     Conclusion:  The present study is strengthen for the discovery three pure chemical compounds from C. quadrangula. Peer Review History: Received 2 April 2019; Revised 22 April; Accepted 7 May, Available online 15 May 2020 UJPR follows the most transparent and toughest ‘Advanced OPEN peer review’ system. The identity of the authors and, reviewers will be known to each other. This transparent process will help to eradicate any possible malicious/purposeful interference by any person (publishing staff, reviewer, editor, author, etc) during peer review. As a result of this unique system, all reviewers will get their due recognition and respect, once their names are published in the papers. We expect that, by publishing peer review reports with published papers, will be helpful to many authors for drafting their article according to the specifications. Auhors will remove any error of their article and they will improve their article(s) according to the previous reports displayed with published article(s). The main purpose of it is ‘to improve the quality of a candidate manuscript’. Our reviewers check the ‘strength and weakness of a manuscript honestly’. There will increase in the perfection, and transparency. Received file Average Peer review marks at initial stage: 4.5/10 Average Peer review marks at publication stage: 7.0/10 Reviewer(s) detail: Name: Ahmad Najib Affiliation: Universitas Muslim Indonesia, Makassar, Indonesia E-mail: [email protected]   Name: Dr. Hatem Sameir Abbas Affiliation: Al-Azhar University, Egypt E-mail: [email protected] Comments of reviewer(s): Similar Articles: A REVIEW ON CONSTITUENTS, PHARMACOLOGICAL ACTIVITIES AND MEDICINAL USES OF GLYCYRRHIZA GLABRA MURRAYA KOENIGI-A BOON IN DIFFERENT PATHOLOGICAL CONDITIONS

scholarly journals PHYTOCHEMICAL PURIFICATION OF ACTIVE CONSTITUENTS ISOLATED FROM ROOT OF THE MEDICINAL HERB, CARALLUMA QUADRANGULA

2020 ◽  
Author(s):  
Jamal AN. Al-Mahweety ◽  
Ammer Al-Fadaly ◽  
Waled Abdo Ahmed
Keyword(s):  
Peer Review ◽  
Folk Medicine ◽  
Phytochemical Analysis ◽  
Initial Stage ◽  
Unique System ◽  
Pure Compounds ◽  
Phytochemical Compounds ◽  
Review Reports ◽  
E Mail

Objective: Present study aim for the purification of quantitative phytochemical compounds from roots of  Caralluma quadrangula belongs to the family Asclepiadaceae. This type of plants can be use as folk medicine  to take care of wide diversity of health  and diseases situation. Methods: Preliminary phytochemical analysis for different type of chemical compounds by using various  chromatographic techniques. The phytochemical characterizations were evaluated by nuclear magnetic resonance and mass spectrometry. Results: The quantitative phytochemical analysis of this species exhibited the presence four pure compounds,  hydroxyoplopan-4-one (4.5 mg), dihydroxyeudesm-4(15)-ene (5.0 mg), and quercetin- rhamnopyranosyl-D-glucopyranose (Rutin) (7.0 mg). Conclusion: From this study, it can be concluded that the species found four pure compounds from C. quadrangula. Peer Review History: Received 25 July 2020; Revised 10 August; Accepted 28 August, Available online 15 September 2020 UJPR follows the most transparent and toughest ‘Advanced OPEN peer review’ system. The identity of the authors and, reviewers will be known to each other. This transparent process will help to eradicate any possible malicious/purposeful interference by any person (publishing staff, reviewer, editor, author, etc) during peer review. As a result of this unique system, all reviewers will get their due recognition and respect, once their names are published in the papers. We expect that, by publishing peer review reports with published papers, will be helpful to many authors for drafting their article according to the specifications. Auhors will remove any error of their article and they will improve their article(s) according to the previous reports displayed with published article(s). The main purpose of it is ‘to improve the quality of a candidate manuscript’. Our reviewers check the ‘strength and weakness of a manuscript honestly’. There will increase in the perfection, and transparency. Received file Average Peer review marks at initial stage: 5.0/10 Average Peer review marks at publication stage: 7.5/10 Reviewer(s) detail: Name: Marwa  A. A. Fayed Affiliation: Faculty of Pharmacy, University of Sadat City, Egypt E-mail: [email protected]   Name: Dr. Ali Gamal Ahmed Al-kaf Affiliation: Sana'a university, Yemen E-mail: [email protected]   Name: Ahmad Najib Affiliation: Department of Pharmacognosy-Phytochemystry Universitas Muslim Indonesia-Indonesia E-mail: [email protected]   Comments of reviewer(s): Similar Articles: A STUDY OF PHYTOCHEMICAL CONSTITUENTS IN CARALLUMA QUADRANGULA PHARMACOGNOSTIC EVALUATION OF GOMPHRENA SERRATA ROOT

scholarly journals CRITICAL REVIEW ON BOMBAX CEIBA, ALOE VERA AND XIMENIA AMERICANA

2020 ◽  
Author(s):  
Rohit Shankar Mane ◽  
Ankala Basappa Vedamurthy
Keyword(s):  
Medicinal Plants ◽  
Peer Review ◽  
Aloe Vera ◽  
Natural Ecosystem ◽  
Human Beings ◽  
Medicinal Uses ◽  
Unique System ◽  
Ximenia Americana ◽  
Review Reports ◽  
E Mail

Therapeutic plants are extensively increased in scenery with their efficient therapeutic properties. India has the greater natural ecosystem from past two decades, near has been a marvelous augment in the applications of natural medicines; though there is still a noteworthy deficiency in the research of medicinal plants and it has the great resources of medicinal plants which are noteworthy to human beings in many ways. The medicinal plants such as Bombax ceiba, Aloe vera and Ximenia Americana are well known to cure several diseases therefore used in different Ayurvedic preparation somehow they are lagging behind in the list of medicinal plants for their applications in drug preparations. These plants has great ethnopharmaceutical and pharmacological properties with therapeutic applications therefore present review gives different aspects of Bombax ceiba, Aloe vera and Ximenia americana and may help to create awareness in society. Peer Review History: Received 25 February 2019; Revised 16 April; Accepted 7 May, Available online 15 May 2020 UJPR follows the most transparent and toughest ‘Advanced OPEN peer review’ system. The identity of the authors and, reviewers will be known to each other. This transparent process will help to eradicate any possible malicious/purposeful interference by any person (publishing staff, reviewer, editor, author, etc) during peer review. As a result of this unique system, all reviewers will get their due recognition and respect, once their names are published in the papers. We expect that, by publishing peer review reports with published papers, will be helpful to many authors for drafting their article according to the specifications. Auhors will remove any error of their article and they will improve their article(s) according to the previous reports displayed with published article(s). The main purpose of it is ‘to improve the quality of a candidate manuscript’. Our reviewers check the ‘strength and weakness of a manuscript honestly’. There will increase in the perfection, and transparency. Received file Average Peer review marks at initial stage: 5.0/10 Average Peer review marks at publication stage: 7.0/10 Reviewer(s) detail: Name: Ahmad Najib Affiliation: Universitas Muslim Indonesia, Makassar, Indonesia E-mail: [email protected]   Name: Dr. Mahmut Yıldıztekin Affiliation: Muğla Sıtkı Koçman University, Turkey E-mail: [email protected] Comments of reviewer(s): Similar Articles: A STUDY ON DIFFERENT PLANTS OF APOCYNACEAE FAMILY AND THEIR MEDICINAL USES A REVIEW ON MEDICINAL USES OF DIFFERENT PLANTS OF EUPHORBIACEAE FAMILY

scholarly journals AN OVERVIEW ON CURRENT REGULATION AND EVALUATION OF BIOCIDAL PRODUCTS

2019 ◽  
Author(s):  
Aslı ŞAHİNER ◽  
Evren ALGIN YAPAR
Keyword(s):  
Peer Review ◽  
Chemical Substance ◽  
Biological Action ◽  
Insect Repellents ◽  
Biocidal Products ◽  
Unique System ◽  
Natural Oil ◽  
Review Reports ◽  
E Mail ◽  
Biocidal Product

A biocidal product is a substance or mixture prepared to limit, destroy, neutralize or control the effects of a harmful microorganism, plants and animals. The active substance in a biocidal product can be a natural oil or extract, a chemical substance or a microorganism, virus or fungus. Biocides consist of four main groups: disinfectants, preservatives (wood, paint, etc.), pest control and other type of biocidal products. A biocidal substance can also be added to a product to make the product itself into a biocidal product. These products range from disinfectants, hand sanitizers, preservatives, insect repellents, to rodenticides and insecticides and are used to protect humans, animals, materials and articles by controlling the intended target organism by a chemical or biological action. To make sure the use of biocidal products do not have unacceptable risks for people, animals and the environment, they are regulated to control their marketing, sale and use. In the current study biocidal products have been overviewed in the scope of current European Union regulations, product types and conformity tests. Peer Review History: UJPR follows the most transparent and toughest ‘Advanced OPEN peer review’ system. The identity of the authors and, reviewers will be known to each other. This transparent process will help to eradicate any possible malicious/purposeful interference by any person (publishing staff, reviewer, editor, author, etc) during peer review. As a result of this unique system, all reviewers will get their due recognition and respect, once their names are published in the papers. We expect that, by publishing peer review reports with published papers, will be helpful to many authors for drafting their article according to the specifications. Auhors will remove any error of their article and they will improve their article(s) according to the previous reports displayed with published article(s). The main purpose of it is ‘to improve the quality of a candidate manuscript’. Our reviewers check the ‘strength and weakness of a manuscript honestly’. There will increase in the perfection, and transparency. Received file Average Peer review marks at initial stage: 5.0/10 Average Peer review marks at publication stage: 7.0/10 Reviewer(s) detail: Name: Dr. Barkat Ali Khan Affiliation: Kampala International University , Uganda E-mail: [email protected]   Name: Dr. Sally A. El-Zahaby Affiliation: Pharos University in Alexandria, Egypt E-mail: [email protected] Comments of reviewer(s):

scholarly journals A REVIEW STUDY ON TRAMADOL ABUSE AMONG EGYPTIAN UNIVERSITY STUDENTS

2020 ◽  
Author(s):  
Lysher Tan Shu Phing ◽  
Muhammad Shahzad Aslam
Keyword(s):  
University Students ◽  
Peer Review ◽  
Data Extraction ◽  
Cross Sectional Study ◽  
Future Research ◽  
Eligibility Criteria ◽  
Cross Sectional ◽  
Male Youth ◽  
Review Reports ◽  
E Mail

Tramadol, which is a medication used for moderate and severe pains, has caused drug abuse and addiction to the Egyptian community. This study aimed to observe the prevalence of tramadol abuse among Egyptian university students. By following the PRISMA reporting guideline, a systematic review of evidence was conducted. Search strategy was conducted through PubMed-NCBI to yield appropriate published literature between 2014-2019, as well as performed literature screening, eligibility criteria, and data extraction. The process of selection yielded a total number of 2 studies to be eligible for the review inclusion criteria. The characteristics evaluated that correlate to tramadol were classified into four groups: gender, smoking, alcohol consumption, and failure in exams before. In general, tramadol showed positively associated with other prevalence characteristics. Tramadol is the second most commonly abused drug among university students in Egypt. The review highlights that tramadol abuse has become a common phenomenon among Egyptian university students which necessitates for ample attention. Future research is recommended to identify the causal effects of tramadol abuse and its role as a potential gateway drug. Peer Review History: Received 2 January 2020;   Revised 22 February; Accepted 1 March, Available online 15 March 2020 UJPR follows the most transparent and toughest ‘Advanced OPEN peer review’ system. The identity of the authors and, reviewers will be known to each other. This transparent process will help to eradicate any possible malicious/purposeful interference by any person (publishing staff, reviewer, editor, author, etc) during peer review. As a result of this unique system, all reviewers will get their due recognition and respect, once their names are published in the papers. We expect that, by publishing peer review reports with published papers, will be helpful to many authors for drafting their article according to the specifications. Auhors will remove any error of their article and they will improve their article(s) according to the previous reports displayed with published article(s). The main purpose of it is ‘to improve the quality of a candidate manuscript’. Our reviewers check the ‘strength and weakness of a manuscript honestly’. There will increase in the perfection, and transparency. Received file Average Peer review marks at initial stage: 5.5/10 Average Peer review marks at publication stage: 7.0/10 Reviewer(s) detail: Name: Hebatallaha A  Moustafa Affiliation: Ain Shams University, Egypt E-mail: [email protected]   Name: Dr. Hassan A.H. Al-Shamahy Affiliation: Sana'a University, Yemen E-mail: [email protected]   Name: Dr. Ali Abdullah Al-yahawi Affiliation: Al-Razi university, Department of Pharmacy, Yemen E-mail: [email protected] Comments of reviewer(s): Similar Articles: A CROSS-SECTIONAL STUDY ON BENZODIAZIPINE (BZD) ABUSERS OF DHAKA CITY: A SOCIO-PSYCHOLOGICAL CONDITION OF BANGLADESH AWARENESS AMONGST YOUTH ABOUT USE AND ABUSE OF STEROIDS IN KARACHI, PAKISTAN ALCOHOL INFLUENCES AGGRESSIVE BEHAVIOUR THAT INCREASES LIKELIHOOD OF INITIATING DATING VIOLENCE AMONG MALE YOUTH IN COLLEGES WITHIN WESTERN COUNTRIES: A SCOPING REVIEW

scholarly journals ENHANCEMENT OF WOUND HEALING BY TOPICAL APPLICATION OF EPIDERMAL GROWTH FACTOR IN ANIMAL MODEL

2020 ◽  
Author(s):  
George Zhu ◽  
Xu HL ◽  
Zhou XP ◽  
Zhi QW
Keyword(s):  
Wound Healing ◽  
Growth Factor ◽  
Epidermal Growth Factor ◽  
Peer Review ◽  
Healing Time ◽  
Epidermal Growth ◽  
Review Reports ◽  
E Mail

Objective: Wound healing is a complex process of biological events involving re-epithelialization and granulation that are mainly mediated by several endogenously released growth factors such as epidermal growth factor. This work was undertaken to study the effects of various doses of locally applied recombinant human epidermal growth factor (rhEGF) on wound healing in rats. Methods: Recombinant human EGF consists of 53 amino acids. In vitro, rhEGF promoted it’s obvious cell growth and proliferation when added to cultured 3T3 cells using MTT assay. In the test groups, in vivo, wound sites were given daily with a solution containing 2, 5, 10, 50ug of EGF spray and 40ug of EGF ointment, respectively. We presented evidence that a significant decreased healing time in wound was observed in all rhEGF groups when compared with the control, and reach to its maximal efficacy at 10ug/ml of rhEGF spray. Results: The rate of wound closure was over 50 per cent at initial 3 days of treatment. Treatment with rhEGF significantly decreased the length of time to over 50 per cent healing by approximately 4-5 days, and that to 70 per cent and 90 per cent healing by approximately 3-4 days and 3 days, respectively. A stimulatory, dose-dependent effect of EGF on wound healing was observed with increased hEGF concentration. In toxicological group, higher doses of 100ug/ml of rhEGF spray was applied by local dorsal incision in rats. Moreover, a dose of single 200ug, single 300ug or 300ug within 24 hours of subcutaneous and intramuscular rhEGF injection was given respectively. There were no significant adverse side effects.Conclusion: Current study recommended a proposal of clinical drug doses in wound at 2µg, 5 µg and 10 µg /ml of rhEGF spray, and 10 µg and even higher 40 µg rhEGF/g of ointment. The results indicated that prepared rhEGF by our genetic engineering is safe, and is emerging in clinical effective use in assisting wound healing time. Peer Review History: Received 8 January 2020;   Revised 12 February; Accepted 2 March, Available online 15 March 2020 UJPR follows the most transparent and toughest ‘Advanced OPEN peer review’ system. The identity of the authors and, reviewers will be known to each other. This transparent process will help to eradicate any possible malicious/purposeful interference by any person (publishing staff, reviewer, editor, author, etc) during peer review. As a result of this unique system, all reviewers will get their due recognition and respect, once their names are published in the papers. We expect that, by publishing peer review reports with published papers, will be helpful to many authors for drafting their article according to the specifications. Auhors will remove any error of their article and they will improve their article(s) according to the previous reports displayed with published article(s). The main purpose of it is ‘to improve the quality of a candidate manuscript’. Our reviewers check the ‘strength and weakness of a manuscript honestly’. There will increase in the perfection, and transparency. Received file Average Peer review marks at initial stage: 6.5/10 Average Peer review marks at publication stage: 8.5/10 Reviewer(s) detail: Name: Asmaa Ahmed Mohamed Ahmed Khalifa   Affiliation: Pharos University, Alexandria, Egypt E-mail: [email protected]   Name: Dr. Sabah Hussien El-Ghaiesh  Affiliation: Tanta University, Egypt E-mail: [email protected] Comments of reviewer(s): Similar Articles: POTENTIAL OF SNAKEHEAD FISH (OPHIOCEPHALUS STRIATUS) IN ACCELERATING WOUND HEALING

scholarly journals PURIFICATION AND BIOLOGICAL ACTIVITIES OF COMBINATION OF HEMI-SYNTHESIZED THIOSEMICARBAZONES OF MITRACARPUS SCABER ZUCC

2020 ◽  
Author(s):  
BAMBOLA Bouraima ◽  
HOUNGBEME Gouton Alban ◽  
FAGBOHOUN Louis ◽  
MEDEGAN Sèdami ◽  
GBAGUIDI Ahokanou Fernand
Keyword(s):  
Liquid Chromatography ◽  
Peer Review ◽  
Biological Activities ◽  
Ethanolic Extract ◽  
Medium Pressure ◽  
Crude Extracts ◽  
Medium Pressure Liquid Chromatography ◽  
Review Reports ◽  
Mitracarpus Scaber ◽  
E Mail

The harvested Mitracarpus Scaber plants are identified in the national herbarium and registered under the number AA. 6252/HLB. During this work, three crude extracts are prepared from three organic solvents, namely dichloromethane; ethanol and hydro ethanol in 50/50 v/v proportion. The respective alkaloid extracts obtained from the corresponding crude extracts served as substrates for the hemi synthesis of thiosemicarbazone totals from thiosemicarbazides. The three hemi-synthesis products obtained were tested on eight (08) strains of germs, namely E. coli ATCC 25922, S. aureus ATCC 25923, E. faecalis ATCC 22921, P. aeruginosa ATCC 27853, C. albicans ATCC 10231, S. typhi, K. pneumoniae and Dermatophilus 146. The ethanolic extract of thiosemicarbazones exhibited the best bioactive activity and was found to be the most selective. By a series of bio guided chromatographies: TLC thin layer chromatography; CPA atmospheric pressure chromatography and medium pressure liquid chromatography. MPLC (medium pressure liquid chromatography), separation on dextran gel: Sephadex® LH20). The use of available spectral data, cross-checked with that of the literature, made it possible to identify and purify three (03) molecules of thiosemicarbazones, making it possible to study the biological activity of their combination. Peer Review History: UJPR follows the most transparent and toughest ‘Advanced OPEN peer review’ system. The identity of the authors and, reviewers will be known to each other. This transparent process will help to eradicate any possible malicious/purposeful interference by any person (publishing staff, reviewer, editor, author, etc) during peer review. As a result of this unique system, all reviewers will get their due recognition and respect, once their names are published in the papers. We expect that, by publishing peer review reports with published papers, will be helpful to many authors for drafting their article according to the specifications. Auhors will remove any error of their article and they will improve their article(s) according to the previous reports displayed with published article(s). The main purpose of it is ‘to improve the quality of a candidate manuscript’. Our reviewers check the ‘strength and weakness of a manuscript honestly’. There will increase in the perfection, and transparency. Received file Average Peer review marks at initial stage: 5.5/10 Average Peer review marks at publication stage: 8.0/10 Reviewer(s) detail: Name: Prof. Dr. Ali Gamal Ahmed Al-kaf Affiliation: Sana'a university, Yemen E-mail: [email protected]   Name: Prof. Dr. Amani S. Awaad Affiliation: College of Pharmacy, Prince Sattam Bin Abdulaziz University, Al-Kharj. KSA E-mail: [email protected] Comments of reviewer(s): Similar Articles: ANTIFUNGAL, CYTOTOXIC AND PHYTOTOXICITY OF AERIAL PART OF RANUNCULUS MURICATUS ANTI-INFLAMMATORY AND ANTI-OXIDANT ACTIVITIES OF METHANOL EXTRACT OF BAPHIA NITIDA

scholarly journals OCCLUSAL CHARACTERISTICS OF THE PRIMARY DENTITION AMONG A SAMPLE OF YEMENI PRE-SCHOOL CHILDREN

2020 ◽  
Author(s):  
Lamia A.T. Bin Yehia ◽  
Khaled A AL-Haddad ◽  
Mohammed A Al-labani ◽  
Hassan Abdulwahab Al-Shamahy ◽  
Hussein M Shaga-aldeen
Keyword(s):  
Peer Review ◽  
School Children ◽  
Intestinal Parasites ◽  
Primary Dentition ◽  
Class I ◽  
Class Iii ◽  
Unique System ◽  
Potential Risk Factors ◽  
Review Reports ◽  
E Mail

Objective: The occlusal features change dynamically in the growing children and any disruption in the complex craniofacial growth process may lead to malocclusion, which is a major concern for the pediatric community because of its effects on dental function and beauty, as well as on the child's psyche. The aim of the present study was to study the prevalence of different occlusal traits in the primary dentition of the randomly selected pre-school children from three to five years in the city of Sana’a, Yemen. Methods: The study includes 1106 pre-school children subjected to a dental examination performed in the school premise, using the Foster and Hamilton criteria for occlusal traits. As well as inter- and intra-calibration tests were conducted for assessing the degree of agreeability. Results: Results of the study showed that the Bilateral flush terminal molar relationship was found in 60%, bilateral mesial step in 27.9%, asymmetrical relationship in 8.5% and distal step in 3.5% of tested children. The Bilateral canine class I was detected in 62.8%, asymmetrical relationship (13.6%), class II (12.5%) and class III (11.1%). Normal over-jet (OJ) of 1-3 mm was identified in 39.2%, decreased OJ <1 mm (32.7%) and edge-to-edge (8.8%). Ideal over-bite (OB) of 1-50% was detected in 64.5% and increased OB of > 50% (19.7%). Conclusion: In conclusion theBilateral flush terminal molar, class I canine relationships, normal overjet (OJ) of 1-3mm were the most commonly found sagittal occlusal traits in the current study. Ideal over-bite (OB) of 1-50% were identified in more than half of the children. Peer Review History: Received 2 February 2020;   Revised 21 February; Accepted 3 March, Available online 15 March 2020 UJPR follows the most transparent and toughest ‘Advanced OPEN peer review’ system. The identity of the authors and, reviewers will be known to each other. This transparent process will help to eradicate any possible malicious/purposeful interference by any person (publishing staff, reviewer, editor, author, etc) during peer review. As a result of this unique system, all reviewers will get their due recognition and respect, once their names are published in the papers. We expect that, by publishing peer review reports with published papers, will be helpful to many authors for drafting their article according to the specifications. Auhors will remove any error of their article and they will improve their article(s) according to the previous reports displayed with published article(s). The main purpose of it is ‘to improve the quality of a candidate manuscript’. Our reviewers check the ‘strength and weakness of a manuscript honestly’. There will increase in the perfection, and transparency. Received file Average Peer review marks at initial stage: 5.5/10 Average Peer review marks at publication stage: 7.0/10 Reviewer(s) detail: Name: Aya Mohammed Mohammed Essawy Affiliation: MTI University- Mokattam, Egypt E-mail: [email protected]   Name: Dr. Nada Farrag Affiliation: Misr International University, Egypt E-mail: [email protected] Comments of reviewer(s): Similar Articles: COCCIDIAN INTESTINAL PARASITES AMONG CHILDREN IN AL-TORBAH CITY IN YEMEN: IN COUNTRY WITH HIGH INCIDENCE OF MALNUTRITION EVALUATION OF THE IMMUNE RESPONSE TO POLIO VACCINE IN MALNOURISHED CHILDREN IN SANA'A CITY PREVALENCE AND POTENTIAL RISK FACTORS OF HEPATITIS B VIRUS IN A SAMPLE OF CHILDREN IN TWO SELECTED AREAS IN YEMEN

scholarly journals QUALITY EVALUATION OF BIOSIMILAR MEDICINES: AN OVERVIEW

2020 ◽  
Author(s):  
Emrah KORKMAZ ◽  
Mehmet Emre ÖZDEMİRHAN ◽  
Evren ALGIN YAPAR
Keyword(s):  
Quality Control ◽  
Peer Review ◽  
Internal Quality ◽  
Control Methods ◽  
Ambient Conditions ◽  
Purification Method ◽  
Factors Affecting ◽  
Manufacturing Method ◽  
Review Reports ◽  
E Mail

Biosimilar medicines are biotherapeutics that are similar in quality, safety and efficacy to previously licensed reference biotherapeutics. The slightest change in any stage of production can cause differences in the product. Among the factors, affecting production can be listed as; host cell selection, fermenter type, ambient conditions, broth, substances used for cell culture, fermentation method and purification method. The similarity should be demonstrated by comparative quality, non-clinical and clinical tests. Research and development studies in the biopharmaceutical field bring diversity of quality control methods along with the formulation and manufacturing method of the biosimilars. Although there are some standardized and validated quality control methods given in the internationally recognized pharmacopoeias, there are many in house methods of biopharmaceutical product owners that can only be used as internal quality control methods by them. The main international sources for quality control methods of biopharmaceutics can be given as pharmacopoeias, International Organization for Standardization standards and Organization for Economic Co-operation and Development methods. In this review manufacturing process, regulatory guidelines and quality control of biosimilar medicines briefly are given. Peer Review History: Received 11 March 2019; Revised 20 April; Accepted 3 May, Available online 15 May 2020 UJPR follows the most transparent and toughest ‘Advanced OPEN peer review’ system. The identity of the authors and, reviewers will be known to each other. This transparent process will help to eradicate any possible malicious/purposeful interference by any person (publishing staff, reviewer, editor, author, etc) during peer review. As a result of this unique system, all reviewers will get their due recognition and respect, once their names are published in the papers. We expect that, by publishing peer review reports with published papers, will be helpful to many authors for drafting their article according to the specifications. Auhors will remove any error of their article and they will improve their article(s) according to the previous reports displayed with published article(s). The main purpose of it is ‘to improve the quality of a candidate manuscript’. Our reviewers check the ‘strength and weakness of a manuscript honestly’. There will increase in the perfection, and transparency. Received file Average Peer review marks at initial stage: 6.0/10 Average Peer review marks at publication stage: 7.5/10 Reviewer(s) detail: Name: Dr. Mohamed Salama Affiliation: Modern University for Technology & Information, Egypt E-mail: [email protected]   Name: Dr.  Maha Khalifa Ahmed Khalifa Affiliation: E-mail: [email protected] Comments of reviewer(s):

scholarly journals COMPARISON BETWEEN THE EFFECTS OF THYMOQUINONE OBTAINED FROM THE SEEDS OF NIGELLA SATIVA AND VERAPAMIL ON THE VOLUME AND ACIDITY OF GASTRIC ACID SECRETION

2020 ◽  
Author(s):  
Rahma Hamayun ◽  
Muhammad Jan ◽  
Muhammad Fazeel
Keyword(s):  
Peptic Ulcer ◽  
Gastric Secretion ◽  
Peer Review ◽  
Gastric Acid ◽  
Nigella Sativa ◽  
Wound Dressings ◽  
Research Centre ◽  
Unique System ◽  
Review Reports ◽  
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Background and Objectives: The over production of gastric acid results in peptic ulcer. This study was done to compare the effects of thymoquinone and Verapamil on volume and acidity of carbachol induced gastric secretion. Methods: There were 24 rabbits used, weighing 1-1.5 kg. The rabbits were kept on fasting for 48 hours. After fasting, the pylorus of each rabbit was ligated. Thymoquinone 5 mg/kg, Carbachol 600mg/kg and Verapamil 10 mg/kg body weight were administered intraperitoneally. Pylorus ligation method was used for getting gastric contents and titration method was used for finding out acidity. Results: Verapamil has been proved very effective for the treatment of many diseases. The drug verapamil inhibits the release of histamine, acetylcholine and gastrin. Verapamil has also shown effects in reducing the secretion of gastric acid. It was found that Thymoquinone reduced the volume, free and total acidity of gastric secretion, which were statistically highly significant when compared with Carbachol (P=0.000) but when we compared the results of Thymoquinones with that of Verapamil, it was non-significant. Conclusions:   It was concluded that Thymoquinone can be used for the treatment of peptic ulcer and all other diseases which are caused by increased gastric acidity like dyspepsia, gastritis and reflux esophagitis. Peer Review History: Received 8 July 2020; Revised 14 August; Accepted 6 September, Available online 16 September 2020 UJPR follows the most transparent and toughest ‘Advanced OPEN peer review’ system. The identity of the authors and, reviewers will be known to each other. This transparent process will help to eradicate any possible malicious/purposeful interference by any person (publishing staff, reviewer, editor, author, etc) during peer review. As a result of this unique system, all reviewers will get their due recognition and respect, once their names are published in the papers. We expect that, by publishing peer review reports with published papers, will be helpful to many authors for drafting their article according to the specifications. Auhors will remove any error of their article and they will improve their article(s) according to the previous reports displayed with published article(s). The main purpose of it is ‘to improve the quality of a candidate manuscript’. Our reviewers check the ‘strength and weakness of a manuscript honestly’. There will increase in the perfection, and transparency. Received file Average Peer review marks at initial stage: 6.0/10 Average Peer review marks at publication stage: 8.0/10 Reviewer(s) detail: Name: Dr. Hatem Sameir Abbas Affiliation: Al-Azhar University, Egypt E-mail: [email protected]   Name: Prof. Dr. Ali Gamal Ahmed Al-kaf Affiliation: Sana'a university, Yemen E-mail: [email protected]   Name: Dr. Gehan Fawzy Abdel Raoof Kandeel Affiliation: National Research Centre, Egypt E-mail: [email protected]   Name: Dr. Mahmut Yıldıztekin Affiliation: Muğla Sıtkı Koçman University, Turkey E-mail: [email protected]   Comments of reviewer(s): Similar Articles: COMPARISION OF ANTIDYSLIPIEMIC POTENTIAL OF 80 MILLIGRAMS OF FENOFIBRATED WITH 8 GRAMS OF NIGELLA SATIVA SEEDS DAILY GC-MS ANALYSIS OF FIXED OILS OF NIGELLA SATIVA SEEDS WOUND DRESSINGS UPLOADED WITH MYRTLE BERRIES EXTRACT AND NIGELLA SATIVA HONEY

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