scholarly journals Efek ekstrak teh hijau (Camellia sinensis (L.) O. Kuntze var. assamica) terhadap berat badan dan kadar malondialdehid wanita overweight

2012 ◽  
Vol 9 (1) ◽  
pp. 41
Author(s):  
Alpha Olivia Hidayati ◽  
Wiryatun Lestariana ◽  
Emy Huriyati

Background: Overweight and obesity were risk factors of various degenerative diseases. Green tea extract contains polyphenol compounds, particularly catechins which act as antioxidants, fat dissolvent and aid lipolysis. Thus, it is necessary to study the use of green tea as an alternative treatment to overcome overweight.Objective: To identify the effect of green tea extract supplementation on body weight and malondialdehide (MDA) level of overweight women in Yogyakarta District Health Office.Method: This was an experimental study with double-blind randomized controlled trial design. Subject of the study were divided into two groups; one group consumed green tea extract capsules and the other consumed placebo. Weight, 6 times 24 hours recall, and level of MDA were measured on every subject.Results: The results revealed that green tea extract has a weight-reducing effect and decrease MDA level of overweight women, though the reduction of weight and MDA level was not significant (p>0,05). Weight loss of 1.3% was observed in the treatment group, whereas the control group has an increase of 0.6% body weight, but the weight change was not significant (p=0.501, p=0.620). Changes in body weight after 12 weeks of treatment showed a significant disparity between the two groups (p=0.000). MDA level decreased by 10% in the treatment group compared to 8.3% in the control group. MDA levels pre and post intervention was significantly different in the treatment group (p=0.006), whereas in the control group there was no significant discrepancy observed (p=0.123). However, changes in MDA levels after 12 weeks of treatment showed no significant differences among groups (p=0.278). The mean nutrient intakes of subjects were still below the recommended dietary allowance (RDA), except for protein.Conclusion: Green tea extract had a weight-reducing effect and decrease MDA level of overweight women in Yogyakarta District Health Office, though the reduction was not statistically significant.

2007 ◽  
Vol 19 (1) ◽  
Author(s):  
Isti Endah Kurniwati ◽  
Juni Handajani ◽  
Regina TC. Tandelilin

Green tea (Camellia sinensis) has been widely known as a healthy drink since long time ago. One of the substances in green tea which can give health benefit is catechin, an antibacterial substance. The purpose of this research is to know the efficacy of rinsing with green tea extract to Streptococcus alpha growth on gingivitis patient’s dental plaque. The research subjects include 30 mild gingivitis patients, and these subjects are divided into two groups: treatment group (20 patients) and control group (10 patients). Ten patients of treatment group rinse their mouth with 0.25% green tea extract and 10 other patients with 0.5% green tea extract. Meanwhile, control group use Bactidol (0.1% Hexetidine). Rinsing the mouth is performed every morning and night for five days. Sampling is conducted on the first and sixth day. Before rinsing data is analyzed using ANOVA and the result shows a significant difference. ANAVA testing then is done using proportion value. ANAVA Testing result shows that there is no significant difference among the patients in the treatment group. This result indicates that the effect of rinsing with 0.25% and 0.5% green tea extract is equivalent to the control (0.1% Hexetidine) to inhibit S. alpha growth on mild gingivitis patient’s dental plaque. From these two concentrations, it has not been known which one is the most effective concentration to inhibit S. alpha growth on mild gingivitis patient.


2014 ◽  
Vol 2014 ◽  
pp. 1-4 ◽  
Author(s):  
Rasool Soltani ◽  
Abbas Haghighat ◽  
Mehrdad Fanaei ◽  
Gholamreza Asghari

Background. Removing tooth results in gingival bleeding. Several measures are taken to stop bleeding. In this study, the effect of green tea extract on cessation of bleeding and oozing after removing of mandibular molars was investigated.Methods. This was a randomized controlled clinical trial carried out on 62 patients who were referred for extraction of their mandibular molars. The volunteers were randomly and equally divided into treatment and control groups. In the first group, green tea extract-impregnated sterile gauze was used after removing the tooth while in the second group, green tea extract-free gauze was applied. Active bleeding and oozing monitoring was done every 5 minutes until cessation of bleeding and one hour after that, respectively. The results were compared usingt-test.Results. The mean ± SD of bleeding duration in green tea group was significantly lower than control group (5.87±1.76versus10.09±3.61minutes,P=0.001). In addition, the number of people with oozing one hour after surgery was significantly lower in the green tea group (6 versus 29 persons,P=0.001).Conclusion. This study showed that green tea extract contributes to significant decline in bleeding of the socket caused by tooth extraction as well as reduction of oozing.


Antioxidants ◽  
2021 ◽  
Vol 10 (7) ◽  
pp. 1026
Author(s):  
Hyeyeong Seo ◽  
Seok-Hee Lee ◽  
Yooheon Park ◽  
Hee-Seok Lee ◽  
Jeong Sup Hong ◽  
...  

Loss of skeletal muscle mass and function with age represents an important source of frailty and functional decline in the elderly. Antioxidants from botanical extracts have been shown to enhance the development, mass, and strength of skeletal muscle by influencing age-related cellular and molecular processes. Tannase-treated green tea extract contains high levels of the antioxidants (−)-epicatechin (EC) and gallic acid that may have therapeutic benefits for age-related muscle decline. The aim of this study was to investigate the effect of tannase-treated green tea extract on various muscle-related parameters, without concomitant exercise, in a single-center, randomized, double-blind, placebo-controlled study. Administration of tannase-treated green tea extract (600 mg/day) for 12 weeks significantly increased isokinetic flexor muscle and handgrip strength in the treatment group compared with those in the placebo (control) group. In addition, the control group showed a significant decrease in arm muscle mass after 12 weeks, whereas no significant change was observed in the treatment group. Blood serum levels of follistatin, myostatin, high-sensitivity C-reactive protein (hs-CRP), interleukin (IL)-6, IL-8, insulin-like growth factor-1 (IGF-1), and cortisol were analyzed, and the decrease in myostatin resulting from the administration of tannase-treated green tea extract was found to be related to the change in muscle mass and strength. In summary, oral administration of tannase-treated green tea extract containing antioxidants without concomitant exercise can improve muscle mass and strength and may have therapeutic benefits in age-related muscle function decline.


2014 ◽  
Vol 10 (4) ◽  
pp. 209
Author(s):  
Ernawati Hardani ◽  
Wiryatun Lestariana ◽  
Susetyowati Susetyowati

Background: Overweight and obesity can cause high body fat total and lipid profile in the blood that brings risk for diseases to the bearer. Some studies on green tea extract supplementation have been undertaken to find out its effect on the fat reduction in children, men, and mice and the result showed a reduction in body fat, weight, appetite, and triglyceride level. This study uses green tea extract supplemented to overweight and obese women. Objective: To find out the reduction of body fat total and lipid profile (total cholesterol, triglyceride, LDL, HDL) in the blood of overweight and obese women personnel of Yogyakarta Municipal Health Office supplemented with green tea extract.Method: The study was randomized double-blinded control trial. The subject of the study was overweight and obese women of 35-55 years old personnel of Yogyakarta Municipal Health Office. Samples were 86 women randomly taken, comprising experiment group and control group, each of which consisting of 43 women. Each group had diet according to individual appetite. Both groups were given capsules of similar form and color but different ingredients: placebo and green tea extract. The experiment took three months. Blood was taken before and after the experiment to identify lipid profile (total cholesterol, triglyceride, LDL, HDL). Body fat total was examined using body fat analyzer. Data analysis used paired t-test.Results: Green tea extract supplementation could significantly reduce body fat total and insignificantly reduce cholesterol level, triglyceride, and LDL, significantly increase HDL in overweight and obese women.Conclusion: Green tea extract supplementation could reduce body fat total and increase HDL (p<0.005).


2016 ◽  
Vol 8 (1) ◽  
Author(s):  
Triva Murtina Lubis

The aim of this study was to determine the effect of green tea (Camelia sinensis) extract on hemoglobin and hematocrit level of Wistar rat (Rattus norvegicus). Sample animals used were 20 rats strain Wistar aged 2.5-3.0 months. Green tea extract was given for 30 days consecutively. Blood collection was conducted via orbitalis sinus for 2 ml using capillary pipette. Rats were fed with standart commercial food (Turbo Feed T.79-4) and aquadest as drinking water ad libitum. This study used completely randomized design (CRD) pattern with 4 treatments and 5 replications. The control group (P0) without any treatment, P1 was given green tea extract 0.045 g/ml/day, P2 was given green tea extract 0.060 g/ml/day, and P3 was given green tea extract 0.075 g/ml/day. Data were analyzed by oneway analysis of variance (Anova). The result showed that mean±SD of hemoglobin levels (g/dl) on each treatment group (P0, P1, P2, and P3) were 11.86±0.55, 12.58±1.40, 11.82±0.69, and 12.50±0.84 respectivey. Mean±SD of hematocrit levels (%) on each treatment group (P0, P1, P2, and P3) were 44.00±4.30, 43.40±1.14, 44.00±1.58, and 42.80±1.79. To conclude, the administration of green tea extract has no effect (P0.05) on haemoglobin and hematocrit levels of Wistar rat. ____________________________________________________________________________________________________________________ Key words: green tea, haemoglobin, haematocrit, Wistar rat


2011 ◽  
Vol 23 (3) ◽  
Author(s):  
Dhona Afriza

This research aimed to identify the effect of inhaling mercury on the hepar cells of white mice and the role of green tea extract as an antioxidant on such hepar cells having exposed to mercury histopathologically. It was an experimental research by using 48 male white mice (Mus musculus) as the sample. The sample was divided into 8 groups i.e.: A, B, C, and D, which were given treatment for 3 and 6 weeks. Each group consisted of 6 mice. A group was a negative control which did not get any treatment. Group B as a positive control group was exposed to mercury. Group C was exposed to mercury and was given green tea extract at dosage 0.52 mg/20 gr of body weight. Group D was exposed by mercury and was given green tea extract at dosage 1.04 mg/ 20 gr of body weight. All white mice in the group B, C, and D were exposed to mercury through inhalation for 4 hours daily. To identified the effect of mercury, the hepar cells in all 4 groups were examined at the 3rd and 6th week by making histopathologic preparation in the Histopathology Laboratory Faculty of Medicine Universitas Andalas. Then, the preparation was examined through Binocular Light Microscope in ordered to see the deficient occurred. The data obtained were analyzed by ANOVA method and independent T-test with confidence level = 95%. It was revealed that the hepar cells that were being exposed to mercury regularly were being degenerates. Then, the amount of green tea extract given reduces the degeneration occurred.


2020 ◽  
Vol 21 (1) ◽  
pp. 31-35
Author(s):  
Basma El-Desoky ◽  
Shaimaa El-Sayed ◽  
El-Said El-Said

Objective: Investigating the effect of green tea extract (GTE) on the testicular damage induced by cadmium chloride CdCl2 in male rats. Design: Randomized controlled study. Animals: 40 male Wistar rats. Procedures: Rats were randomly divided into four groups: A) control group (each rat daily received pellet diet); B) GTE group each rat daily received pellet diet as well as 3 ml of 1.5 % w/v GTE, C) CdCl2 group each rat was I/P injected a single dose of 1 mg/kg CdCl2, then daily received pellet diet, and D) CdCl2+GTE group each rat was I/P injected a single dose of 1 mg/kg CdCl2 then daily received pellet diet as well as 3 ml of 1.5 % w/v GTE. After 30 days, blood samples were collected for hormonal assays (testosterone, FSH, and LH). In addition, both testes were collected; one of them was used for quantification of 17-beta hydroxysteroid dehydrogenase III (17β-HSDIII) gene expression using a real-time PCR. The other testis was used for determination of catalase and reduced glutathione; GSH, Nitric oxide (NO) and malondialdehyde (MDA) levels. Results: CdCl2 decreased serum testosterone levels and its synthesis pathway (17β-HSDIII testicular gene expression). While antioxidants catalase and GSH were reduced, oxidants MDA were enriched in the testes of CdCl2-poisoned rats. This CdCl2-promoted testicular dysfunction was corrected via the administration of GTE to male rats. Conclusion and clinical relevance: GTE could be used as a remedy for protecting against CdCl2-induced testicular damage in male rats.


2017 ◽  
Vol 22 ◽  
pp. 1-6 ◽  
Author(s):  
Monallisa Alves Ferreira ◽  
Anna Paula Oliveira Gomes ◽  
Ana Paula Guimarães de Moraes ◽  
Maria Luiza Ferreira Stringhini ◽  
João Felipe Mota ◽  
...  

2021 ◽  
Vol 34 (2) ◽  
pp. 198-204 ◽  
Author(s):  
Suherni Susilowati ◽  
Trilas Sardjito ◽  
Imam Mustofa ◽  
Oky Setio Widodo ◽  
Rochmah Kurnijasanti

Objective: The aim of this study was to ascertain the effects of adding green tea extract (GTE) to skim milk-egg yolk (SM-EY) extender on both the quality of post-thawed bull semen and the pregnancy rates of the recipient cows.Methods: Twelve ejaculates from four Simmental bulls, aged 3 to 5 years and weighing 900 to 950 kg, were diluted SM-EY extender, added with 0, 0.05, 0.1, and 0.15 mg GTE/100 mL extender and then frozen. After four weeks storage in liquid nitrogen, the sperm were thawed and evaluated for viability, motility, intact plasma membrane (IPM), and DNA fragmentation. Meanwhile, the estrus cycles of 48 recipient cows were synchronized by intramuscular administration of a single injection of 5 mg prostaglandin F2α. Estrus cows were divided into four equal groups and inseminated artificially 18 to 20 h after the onset of estrus by using semen from each extender group. Pregnancy was diagnosed by measuring serum progesterone levels at 21 days, followed by transrectal palpation 90 days after insemination.Results: The findings revealed that adding 0.1 mg of GTE/100 mL extender produced the highest percentages of sperm viability (70.67%±1.75%), motility (69.17%±1.47%), and IPM (69.23%±1.21%) and the lowest percentage of DNA fragmentation (3.00%±0.50%). The pregnancy diagnosis revealed that all cows (36/36) inseminated using frozen semen in GTE addition extender were pregnant (pregnancy rate 100%), whereas the pregnancy rate of the control group was 83.33% (10/12).Conclusion: It may be concluded that 0.1 mg GTE/100 mL extender yields the best quality of spermatozoa and that all variants doses of GTE in extender produce a higher pregnancy rate among recipient cows.


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