When Is Immunohistochemistry Useful in Assessing Tumor Necrotic Tissue?

2021 ◽  
Vol 41 (1) ◽  
pp. 197-201
Author(s):  
ELZBIETA BOGAJEWSKA-RYLKO ◽  
NAVID AHMADI ◽  
MARTA PYREK ◽  
BEATA DZIEKAN ◽  
VIOLETTA FILAS ◽  
...  
Keyword(s):  
Necrotic Tissue

Gangrena de Fournier. Reporte de caso

2020 ◽  
Vol 63 (5) ◽  
pp. 26-30
Author(s):  
Paloma Pérez Ladrón de Guevara ◽  
Georgina Cornelio Rodríguez ◽  
Oscar Quiroz Castro
Keyword(s):  
Mortality Rate ◽  
Necrotizing Fasciitis ◽  
Broad Spectrum ◽  
Soft Tissues ◽  
Fournier’S Gangrene ◽  
Type Ii ◽  
Necrotic Tissue ◽  
Fournier's Gangrene ◽  
Necrotizing Fascitis ◽  
Key Words Fournier's Gangrene

Fournier’s Gangrene is a type II necrotizing fascitis that leads to thrombosis of small subcutaneous vessels and spreads through the perianal and genital regions and the skin of the perineal. Most cases have a perianal or colorectal focus and in a smaller proportion it originates from the urogenital tract. The mortality rate varies between 7.8 and 50%1-3, only timely diagnosis decreases the morbidity and mortality of this condition. Treatment includes surgical debridement of all necrotic tissue and the use of broad-spectrum antibiotics. Key words: Fournier’s gangrene; gangrene; necrotizing fasciitis; infectious necrotizing of soft tissues.

Maggot Treatment of Necrotic Toe Developed After Traumatic Subtotal Amputation

2021 ◽  
pp. 153473462199728
Author(s):  
Erdem Sahin ◽  
Bedri Karaismailoglu ◽  
Mehmed Nuri Tutuncu ◽  
Erdal Polat ◽  
Huseyin Botanlioglu
Keyword(s):  
Chronic Wounds ◽  
Necrotic Tissue ◽  
Complete Necrosis ◽  
Maggot Debridement Therapy

Maggot debridement therapy (MDT) has been used for years in the treatment of chronic wounds and necrotic tissues. We report a case of subtotally amputated third toe that was treated with MDT after reattachment and developing complete necrosis. The necrotic toe was replaced with viable tissue and the wound healed completely after 2 weeks of MDT application. This case points out the regenerative effects of MDT besides its mechanical debridement effect on the necrotic tissue.

Proceso de Optimización y Evaluación de una Antena Micro-coaxial para el Tratamiento de Tumores Óseos

2021 ◽  
Author(s):  
◽  
S. E. Rojas Hernández
Keyword(s):  
Quality Of Life ◽  
Radiation Therapy ◽  
Thermal Ablation ◽  
Bone Tumors ◽  
Tumor Volume ◽  
Microwave Antenna ◽  
Comsol Multiphysics ◽  
Necrotic Tissue ◽  
The One

Bone tumors are commonly treated with surgery (amputation), radiation therapy, and chemotherapy; however, its side effects compromise the patient’ quality of life. Thermotherapy is a less aggressive alternative to treat these tumors. In thermal ablation temperatures between 60 °C-100 °C must be reached in the tumor. The process to design and optimize a one-slot microwave antenna by using COMSOL Multiphysics, is proposed. An axi-symmetric 2D parametric study was carried out, in which 576 scenarios (antenna designs) were analyzed to choose the one that allowed higher energy transmission, temperature increases in the ablation range, larger areas of necrotic tissue, etc. From this study, the best scenario was chosen to evaluate its performance by using a 3D anatomical model. The final optimized antenna presented a SWR = 1.45; moreover, it was possible to observed that the 67.35% of tumor volume reaches ablation temperatures.

Cercospora duddiae. [Descriptions of Fungi and Bacteria].

1987 ◽  
Author(s):  
S. Little
Keyword(s):  
Sierra Leone ◽  
Papua New Guinea ◽  
Geographical Distribution ◽  
West Indies ◽  
Leaf Surface ◽  
Narrow Band ◽  
Necrotic Tissue ◽  
Leaf Base ◽  
Leaf Spots ◽  
Water Splash

Abstract A description is provided for Cercospora duddiae. Information is included on the disease caused by the organism, its transmission, geographical distribution, and hosts. HOSTS: Allium ascalonicum, A. cepa, A. fistulosum, A porrum, A. sativum. DISEASE: Leaf spot or withertip on onion and garlic. The symptoms vary on the different host species. On onion circular, chlorotic spots 3-5 mm diam. form mainly on the tip of the leaf, gradually decreasing in number towards the leaf base. The lesions at the leaf tip coalesce, forming a dry greyish-brown area, and in severe cases the entire leaf tip may be killed. The base of the leaf is mottled with brown necrotic leaf spots. Eventually the necrotic tissue may spread down the leaf surface, delimited by a narrow band (3 mm) of chlorotic tissue (Welles, 1923). Rarely does the disease cause much damage (Chupp & Sherf, 1960). GEOGRAPHICAL DISTRIBUTION: Africa: Mauritius, Nigeria, Sierra Leone, Somalia, Uganda; Asia: Borneo, Brunei, Burma, India, Indonesia, Oman, The Yemen; Australasia: Papua New Guinea; North America: West Indies (Barbados, Jamaica). TRANSMISSION: By air-borne or water-splash dispersed conidia, and by transportation with onion parts. The fungus is also reported to be seed borne (Chupp & Sherf, 1960).

Prediction of healing progress of pressure ulcers by distribution analysis of protein markers on necrotic tissue: A retrospective cohort study

2015 ◽  
Vol 23 (5) ◽  
pp. 772-777 ◽  
Author(s):  
Aya Kitamura ◽  
Mikako Yoshida ◽  
Takeo Minematsu ◽  
Gojiro Nakagami ◽  
Shinji Iizaka ◽  
...  
Keyword(s):  
Cohort Study ◽  
Retrospective Cohort Study ◽  
Retrospective Cohort ◽  
Pressure Ulcers ◽  
Distribution Analysis ◽  
Necrotic Tissue ◽  
Protein Markers

scholarly journals A comparative study in the management of fistula in ANO using various modalities

2018 ◽  
Vol 5 (6) ◽  
pp. 2223 ◽  
Author(s):  
Ramachandra M. L. ◽  
Mayank Garg
Keyword(s):  
Fistulous Tract ◽  
Selection Method ◽  
Fistula Tract ◽  
Internal Opening ◽  
Necrotic Tissue ◽  
Fistula In Ano ◽  
Sphincter Function ◽  
Medical College ◽  
Operative Complications ◽  
Comparative Prospective Study

Background: Fistula in ano is a track that connects deeply the anal canal or rectum to the skin around the anus. Fistula in ano most commonly follows an anorectal sepsis1. The main principles of management of anal fistula are closure of internal opening of fistula tract, drainage of infection or necrotic tissue, and eradication of fistulous tract with preservation of sphincter function. The objectives were to compare the various aspects like per operative complications, post-operative complications, mean hospital stay in the treatment of fistula in ano using various modalities like fistulotomy, fistulectomy, setons and lift procedure.Methods: This is a randomised, comparative, prospective study of 80 cases of fistula in ano, presenting at surgical opd of K.R. Hospital, Mysore attached to Mysore Medical College and research Institute. Out of which, 20 cases are treated by fistulectomy, 20 by seton, 20 by fistulotomy and the rest 20 cases by LIFT procedure by random selection method, during period of NOVEMBER 1, 2016 to 31st October 2017.Results: Most common age of presentation is 31-40 years and more common in males then females (M:F= 2.3:1 ). Per operative complications include bleeding seen more in patients undergoing fistulectomy. Per operative course of LIFT procedure patients was complication free. Postoperative pain seen more in patients undergoing setons procedure.Conclusions: we conclude that LIFT procedure and Fistulotomy were acceptable procedures for simple, uncomplicated low lying and high lying fistula.

scholarly journals EFFECTIVITY OF INDONESIAN HONEY ON DIABETIC FOOT ULCERS HEALING PROCESS: OBSERVATIONAL CASE STUDY

2019 ◽  
Vol 2 (2) ◽  
pp. 20-28
Author(s):  
Anita Sukarno ◽  
Nur Hidayah ◽  
Musdalifah Musdalifah
Keyword(s):  
Diabetic Foot ◽  
Healing Process ◽  
Cost Effective ◽  
Tissue Type ◽  
Foot Ulcers ◽  
Wound Healing Process ◽  
Diabetic Foot Ulcers ◽  
Necrotic Tissue

Background: Diabetic foot ulcers were common diabetes complication that progressively growth globally. The effectivity of Manuka honey in wound healing process was huge published currently. Modern dressing and Manuka honey may not affordable and cost effective since these dressings were not produced originally in Indonesia. In addition, the published study of Indonesian honey is still lack. Therefore, we conducted this study to investigate the effectivity of Indonesian honey in diabetic foot ulcers healing process. Method: This study design was observational case study. This study was conducted among type 2 diabetes with diabetic foot ulcers in Griya Afiat Homecare and ETN Center in Makassar City, Indonesia from March to June 2014. The Bates Wound Assessment Tool (BWAT) were used to collect the score of diabetic foot ulcer healing process regarding wound size, depth, edges, undermining, necrotic tissue type, necrotic amount, granulation, epithelization, exudate type and amount, surrounding skin color, edema and induration. Descriptive, Independent t-test, Analysis of Variance (ANOVA) and Wilcoxon signed rank test were conducted appropriately. Results: In total, 10 type 2 diabetes patients with diabetic foot ulcers were participated. The factors associated with wound healing process were diabetes treatment (t= 2.44, p= 0.041) and primary dressing (t= -2.76, p= 0.025). The effect of honey primary dressing was in reducing wound size (p= 0.043), improving necrotic tissue type (p= 0.041), reducing necrotic tissue amount (p= 0.042), increasing granulation (p= 0.038) and epithelization (p= 0.042). In the counterpart, the effect of modern dressing was in improving necrotic tissue type (p= 0.046) and increasing granulation (p= 0.042). Conclusion: Indonesian honey is beneficial on diabetic foot ulcers healing process. Recommendation: Therefore, findings suggest that honey should be considered as the alternative, cost effective and beneficial wound dressing on the diabetic foot ulcers.

scholarly journals Application of Artificial Dermal Graft Combined with Fascia Sleeve Flap in the Treatment of Chronic Bone and Steel Plate Exposed Wounds of Lower Extremities

2021 ◽  
Author(s):  
Yong Li ◽  
Zhi-bo Zhang ◽  
Ji-song Liu ◽  
Zhu-min Wu ◽  
Xin-cheng Sun ◽  
...  
Keyword(s):  
Chronic Wounds ◽  
Steel Plate ◽  
Wound Dehiscence ◽  
Severe Trauma ◽  
Lower Limbs ◽  
Bone Plate ◽  
Good Effect ◽  
Necrotic Tissue ◽  
Sinus Formation ◽  
Neurovascular Flap

Abstract Background:Bone tendon or graft exposure such as steel plate is common after severe trauma of lower extremity.The traditional repair method is to use a variety of skin flaps to cover the exposure, but the wound can not heal after operation, or the wound dehiscence, ulcer, sinus, etc. occur again after short healing, and the bone plate is exposed again.The reason for this result is that the space around the bone plate is not well closed when the flap is covered，dead space is formed, blood and exudate accumulate, hematoma forms or infection occurs, and finally the wound breaks.Also due to swelling and contracture after flap operation,the tension of the suture between the flap and the receiving area is too large and becomes thin and cracked, forming an exposed state.In order to solve the above problems, we have carried out the research on "Application of artificial gradient combined with fascia sleep flap in the treatment of chronic bone and steel plate exposed woods of lower extremes".Methods:In this paper, 11 cases of chronic wounds with bone exposure and skin necrosis after steel plate implantation were selected. First stage is the wound bed preparation including primary wound expansion,removal of necrotic tissue and incision of sinus wall, removal of deep necrotic bone and fibrotic scarred skin on the outer wall of steel plate to normal tissue on the outer edge of the wound, removal of precipitated peptone and purulent fur in the hole, periphery and bone space of the steel plate, and removal of tendon tissue with basal necrosis and disintegration of the wound. After vacuum sealing drainage (VSD) 1~2 weeks, the peritraumatic basal granulation tissue grew well and there was no necrotic tissue in the wound. In the second stage, the exposed bone was covered with artificial dermis, the steel plate hole or the periphery and the basal space were filled, and the exposed steel plate was completely embedded, and then the fascia sleeve flap was transplanted to cover the wound. The sural neurovascular flap was performed in 6 cases and the lateral superior malleolar artery perforator flap in 1 case. Results:The flap survived well in all 11 cases. During the follow-up of 6 months to the removal of the plate, there was no case of rupture, exposure and sinus formation.Conclusions:Artificial dermal covering combined with fascial sleeve flap transplantation can effectively avoid wound dehiscence or sinus formation caused by foreign body retention, infection and flap contracture,It has good effect in repairing chronic wounds with bone plate exposure after severe trauma of lower limbs,.

scholarly journals Staphylococcus Vs Pseudomonas: The Fundamental Role of 1% Cream Micronized Silver Sulfadiazine as a Therapy of Excellence to Combat Bacterial Superinfection– Observational Study

2020 ◽  
Vol 3 (1) ◽  
Keyword(s):  
Observational Study ◽  
Silver Sulfadiazine ◽  
Necrotic Tissue ◽  
Ideal Medium ◽  
Bacterial Superinfection

A wound, due to the loss of skin continuity and the presence of necrotic tissue, is an ideal medium for the multiplication of germs. The infection is the main enemy of a wound because it delays its healing and promotes chronicization

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