scholarly journals Mechanism Development of Diabetic Microangiopathy and Opportunity of Diabetic Warning

2018 ◽  
Vol 25 (2) ◽  
Author(s):  
S. M. Genyk

Specific general defeat of arteriols, capillaries and veins at a diabet mellitus consists in the bulge of basale membrane of shallow vessels, laying of glycoproteins in a wall and proliferation of endothelium. A hyperglycaemia results in increasing of blood plasma, membranes and cages of level of free radicals on a background insufficiency of enzymes of the protective antioxidant system. Determination of the state insulin tolerance to the people with excessive body weight and obesity, by a hyperpiesis, problems with the lack of fats, by a gout and other endocrine diseases already on the stage of credible violation of carbohydrate exchange gives an opportunity in good time to conduct the correction of possible defeats of microvasculature toxic action of high concentration of glucose.

2014 ◽  
Vol 60 (4) ◽  
pp. 43-46
Author(s):  
S T Valieva

We have undertaken a cohort study of 659 mother-child pairs for the determination of the prevalence and main risk factors of excessive body mass in the children of an Azerbaidjan population aged from 2 to 5 years. The anthropometric calculations were carried out as recommended by the relevant WHO program (Antro). The results of the study give reason to estimate the prevalence and risk factors of excessive body mass in the population of interest at 16.1%. The frequency of excessive body mass in the children delivered via Cesarean section was thrice that in the naturally born children; it was associated with the body weight at birth over 4000 grams and the start on solid foods before the age of 4 months. No relationship was documented between the mode of feeding and excessive body weight after the age above 2 years.


1976 ◽  
Vol 68 (2) ◽  
pp. 287-303 ◽  
Author(s):  
J Kyte

The distribution of (Na+ + K+) ATPase over the plasma membranes of distal convoluted tubules from canine kidney has been determined. This enzyme is responsible for the coupled active transport of Na+ and K+ across animal cell membranes. Ultrathin frozen sections were cut from fragments of renal cortex and specifically stained with antibodies, which recognize antigenic sites on the enzyme, and ferritin-conjugated goat antirabbit gamma-globulins. It is demonstrated that (Na+ + K+) ATPase is distributed uniformly and at high concentration over the plasma membranes which form the intercellular spaces of this epithelium. The enzyme is located on the luminal surface of the tubules as well but at a much lower concentration. These results, in combination with those of previous determinations of the cation fluxes across this epithelium, can be used to formulate a complete description of the cation movements through this tissue.


2007 ◽  
Vol 35 (06) ◽  
pp. 1037-1046 ◽  
Author(s):  
Yolanda Y. Pérez ◽  
Enrique Jiménez-Ferrer ◽  
Alejandro Zamilpa ◽  
Marcelino Hernández-Valencia ◽  
Francisco J. Alarcón-Aguilar ◽  
...  

Insulin resistance, which precedes type 2 diabetes mellitus (T2DM), is a widespread pathology associated with the metabolic syndrome, myocardial ischemia, and hypertension. Finding an adequate treatment for this pathology is an important goal in medicine. The purpose of the present research was to investigate the effect of an extract from Aloe vera gel containing a high concentration of polyphenols on experimentally induced insulin resistance in mice. A polyphenol-rich Aloe vera extract (350 mg/kg) with known concentrations of aloin (181.7 mg/g) and aloe-emodin (3.6 mg/g) was administered orally for a period of 4 weeks to insulin resistant ICR mice. Pioglitazone (50 mg/kg) and bi-distilled water were used as positive and negative controls respectively. Body weight, food intake, and plasma concentrations of insulin and glucose were measured and insulin tolerance tests were performed. The insulin resistance value was calculated using the homeostasis model assessment for insulin resistance (HOMA-IR) formula. Results showed that the polyphenol-rich extract from Aloe vera was able to decrease significantly both body weight ( p < 0.008) and blood glucose levels ( p < 0.005) and to protect animals against unfavorable results on HOMA-IR, which was observed in the negative control group. The highest glucose levels during the insulin tolerance curve test were in the negative control group when compared to the Aloe vera extract and pioglitazone treated mice ( p < 0.05). In conclusion, Aloe vera gel could be effective for the control of insulin resistance.


2014 ◽  
Vol 14 (1) ◽  
Author(s):  
Albane BR Maggio ◽  
Xavier E Martin ◽  
Catherine Saunders Gasser ◽  
Claudine Gal-Duding ◽  
Maurice Beghetti ◽  
...  

2015 ◽  
Vol 2015 ◽  
pp. 1-5 ◽  
Author(s):  
Leila Shafie Bafti ◽  
Maryam Alsadat Hashemipour ◽  
Hamidreza Poureslami ◽  
Zeinab Hoseinian

The aim of the present study was to evaluate the relationship between BMI and tooth decay in a population of Iranian children. In this cross-sectional descriptive/analytical study, 1482 children were selected from kindergartens and preschool centers in Kerman, Iran. The children underwent examination of deciduous teeth (using the dmft index) after determination of height and weight for calculation of BMI. The relationship between BMI (after adjustment for age) and dmft was determined using Poisson’s regression model. The mean of dmft in children with normal BMI was 1.5-fold that in subjects with extra body weight. Age had a significant effect on dmft. In addition, dmft was higher in boys compared to girls. The results of the present study showed that caries rate in the deciduous teeth of 3–6-year-old children decreases with an increase in body weight.


2021 ◽  
Vol 31 (3) ◽  
pp. 218-226
Author(s):  
S Akter ◽  
SC Das ◽  
AS Apu ◽  
T Ahmed ◽  
A Lahiry ◽  
...  

The present study was conducted to determine the early sex in turkeys by observation of the differences in body weight between male and female birds. A total of 30-day old black color unsexed poults having almost similar body weight at hatching were considered for the experimentation and housed at the Poultry Farm of Bangladesh Agricultural University, Mymensingh-2202, Bangladesh. All birds were reared up to 12 weeks of age under intensive management with supplementation of commercial broiler starter and grower feeds. Birds were reared under similar management conditions. Significantly higher (p<0.01) body weight was attained in male poults (104g/bird) than the female (90g/bird) at the end of 1st week of age. Similarly, at the end of 2nd week of age higher (p<0.01) body weight attained by male poults (198.31g/bird) than the female (162.13g/bird). At the end of 3rd weeks of age male poults attained higher (p<0.01) body weight (307.23g/bird) than the female (251.33g/bird). After 4 weeks of rearing, male turkeys attained significantly higher (p<0.01) live body weight (424.46g/bird) than the female turkeys (347.87g/bird). The weekly average body weight gains of male and female birds were 94.18g/bird and 76.5g/bird, respectively. Thus, the male and female birds were successfully identified on the basis of differences in their body weight. Weekly feed intake for both the male and female birds was also increased with their age. Up to 4 weeks of age, both the male and female poults consumed same amount of feed (753.46g/bird). The FCR of male and female poults differed non-significantly in 1st, 3rd and 4th week. On the contrary, in 2nd week of age the FCR of male poults (1.60) was significantly lower (p<0.01) than female (2.11). Survivability was 100% up to 4th week of age irrespective of sex of the poults. The birds were reared up to 12 weeks of age until to confirm their sex by observation of the phenotypic appearance. Results of the phenotypic observation of male and female birds correspondence hundred percent accuracy with the results obtained in body weight based differences between male and female birds. It is therefore concluded that farmers can identify male or female poults as early as first week of age on the basis of body weight differences. Progressive Agriculture 31 (3): 218-226, 2020


2018 ◽  
Vol 20 (3) ◽  
pp. 250-254
Author(s):  
Agnieszka Pawelak ◽  
Maciej Ornat ◽  
Krzysztof Pachołek ◽  
Agnieszka Wróblewska ◽  
Bartosz Jerczak ◽  
...  

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