scholarly journals Laser-Based Means for Accelerating Nuclear Decay Rate

2020 ◽  
Author(s):  
Robert Lascola ◽  
Michael Thomas ◽  
Simona Murph ◽  
David DiPrete ◽  
Kalee Fenker
Keyword(s):  
2020 ◽  
Author(s):  
Anusha Chaudhuri ◽  
Subhadeep Das ◽  
Mayukh Banerjea ◽  
Biswadip Das

In Saccharomyces cerevisiae, the nuclear exosome/Rrp6p/TRAMP participates in the 3'-end processing of several precursor non-coding RNAs. Here we demonstrate that the depletion of nucleus-specific 3'to 5' exoribonuclease Rrp6p and its co-factor Rrp47p led to the specific and selective enhancement of steady-state levels of mature small non-coding RNAs (sncRNAs) that include 5S and 5.8S rRNAs, snRNAs and snoRNAs, but not 18S and 25S rRNAs. Most importantly, their steady-state enhancement does not require the exosome, TRAMP, CTEXT or Rrp6p-associated Mpp6p. Rrp6p/47p-dependent enhancement of the steady-state levels of sncRNAs is associated with the diminution of their nuclear decay-rate and requires their polyadenylation before targeting by Rrp6p, which is catalyzed by both the canonical and non-canonical poly(A) polymerases, Pap1p and Trf4p. Consistent with this finding, the Rrp6p and Rrp47p were demonstrated to exist as an exosome-independent complex. Thus, Rrp6p-Rrp47p defines a core nuclear exosome-independent novel turnover system that targets the small non-coding RNAs.


2021 ◽  
Vol 75 (4) ◽  
Author(s):  
A. Ray ◽  
P. Das ◽  
A. K. Sikdar ◽  
S. Pathak ◽  
N. Aquino ◽  
...  

2009 ◽  
Vol 679 (2) ◽  
pp. 106-110 ◽  
Author(s):  
A. Ray ◽  
P. Das ◽  
S.K. Saha ◽  
A. Goswami ◽  
A. De

1977 ◽  
Vol 32 (3-4) ◽  
pp. 345-361 ◽  
Author(s):  
K.-P. Dostal ◽  
M. Nagel ◽  
D. Pabst

Abstract This paper is intended to provide a concise introductory review of the fundamental principles underlying the higher-order effects of nuclear decay rate variations which may be produced by physical or chemical means. The first part of the paper embraces the theoretical foundations of the subject matter, and the second deals with methodological and experimental questions. Several tables summarize published experimental results and the pertinent literature.


1995 ◽  
Vol 32 (2) ◽  
pp. 45-52 ◽  
Author(s):  
H. Z. Sarikaya ◽  
A. M. Saatçi

Total coliform bacteria have been chosen as the indicator organism. Coliform die-away experiments have been carried out in unpolluted sea water samples collected at about 100 m off the coastline and under controlled environmental conditions. The samples were transformed into one litre clean glass beakers which were kept at constant temperature and were exposed to the solar radiation. The membrane filter technique was used for the coliform analysis. The temperature ranged from 20 to 40° C and the dilution ratios ranged from 1/50 to 1/200. Coliform decay rate in the light has been expressed as the summation of the coliform decay rate in the dark and the decay rate due to solar radiation. The solar radiation required for 90 percent coliform removal has been found to range from 17 cal/cm2 to 40 cal/cm2 within the temperature range of 25 to 30° C. Applying the linear regression analysis two different equations have been given for the high (I>10 cal/cm2.hour) and low solar intensity ranges in order to determine the coliform decay rate constant as a function of the solar intensity. T-90 values in the light have been found to follow log-normal distribution with a median T-90 value of 32 minutes. The corresponding T-90 values in the dark were found to be 70-80 times longer. Coliform decay rate in the dark has been correlated with the temperature.


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