scholarly journals Dosimetric Verification of Dose Distribution as Three Dimensional Intensity Modulated Radiation Therapy based MRI Using Polymer Gel

2016 ◽  
Vol 8 (8) ◽  
pp. 1-11
Author(s):  
M. El. Sayed ◽  
F. SAID ◽  
A. Dakrory ◽  
T. Hegazy ◽  
H. Abdelghany
Keyword(s):  
Radiation Therapy ◽  
Dose Distribution ◽  
Three Dimensional ◽  
Intensity Modulated Radiation Therapy ◽  
Polymer Gel ◽  
Intensity Modulated ◽  
Dosimetric Verification

MAGIC-type polymer gel for three-dimensional dosimetry: Intensity-modulated radiation therapy verification

2003 ◽  
Vol 30 (6) ◽  
pp. 1264-1271 ◽  
Author(s):  
Helen Gustavsson ◽  
Anna Karlsson ◽  
Sven Å. J. Bäck ◽  
Lars E. Olsson ◽  
Pia Haraldsson ◽  
...  
Keyword(s):  
Radiation Therapy ◽  
Three Dimensional ◽  
Intensity Modulated Radiation Therapy ◽  
Polymer Gel ◽  
Intensity Modulated

Three-dimensional versus four-dimensional dose calculation for breast intensity-modulated radiation therapy

2020 ◽  
Vol 93 (1110) ◽  
pp. 20200047
Author(s):  
Joo-Hyun Chung ◽  
Minsoo Chun ◽  
Jung-in Kim ◽  
Jong Min Park ◽  
Kyung Hwan Shin
Keyword(s):  
Radiation Therapy ◽  
Dose Distribution ◽  
Respiratory Motion ◽  
Three Dimensional ◽  
Intensity Modulated Radiation Therapy ◽  
Dose Calculation ◽  
Left Breast ◽  
Time Duration ◽  
Intensity Modulated ◽  
Calculated Dose

Objective: To analyze the effect of intra- and interfractional motion during breast intensity modulated radiation therapy (IMRT) by calculating dose distribution based on four-dimensional computed tomography (4DCT). Methods: 20 patients diagnosed with left breast cancer were enrolled. Three-dimensional CT (3DCT) along with 10 phases of 4DCT were collected for each patient, with target volumes independently delineated on both 3DCT and all phases of 4DCT. IMRT plans were generated based on 3DCT (43.2 Gy in 16 fractions). The plan parameters for each segment were split into phases based on time duration estimates for each respiratory phase, with phase-specific dose distributions calculated and summated (4D-calculated dose). The procedure is repeated for 16 fractionations by randomly allocating starting phase using random-number generation to simulate interfractional discrepancy caused by different starting phase. Comparisons of plan quality between the original and 4D-calculated doses were analyzed. Results: There was a significant distortion in 4D-calculated dose induced by respiratory motion in terms of conformity and homogeneity index compared to those of the original 3D plan. Mean doses of the heart and the ipsilateral lung were significantly higher in the 4D-calculated doses compared to those of the original 3D plan (0.34 Gy, p = 0.010 and 0.59 Gy, p < 0.001), respectively). The mean internal mammary lymph node (IMN) dose was significantly greater in the 4D-calculated plan, compared to the original 3D plan (1.42 Gy, p < 0.001). Conclusions: IMN doses should be optimized during the dose-calculation for the free-breathing left breast IMRT. Advances in knowledge: The interplay effect between respiratory motion and multileaf collimator modulation caused discrepancies in dose distribution, particularly in IMN.

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