Combined Interstitial and Intracavitary High-Dose Rate Brachytherapy of Cervical Cancer

High-dose-rate brachytherapy by remote afterloading is now performed under three-dimensional image guidance by CT or MRI. Three-dimensional image-guided brachytherapy in cervical cancer disclosed that the traditional intracavitary brachytherapy by Manchester method cannot deliver an adequate dose to the large tumor with resulting local recurrence. To improve the local control rate, combined interstitial and intracavitary (hybrid) brachytherapy can increase the dose to the large parametrial involvement without increasing the dose to the rectum and bladder. Whether hybrid brachytherapy can be performed safely on a multi-institutional basis remains to be studied. From 2015, phase I/II study of hybrid brachytherapy was launched in Japan, and it was revealed that hybrid brachytherapy can be performed safely and with a high quality of radiation dose distribution in a multi-institutional study. In Japan, the number of patients undergoing hybrid brachytherapy in cervical cancer is rapidly rising. Education and clinical trial are very important to establish hybrid brachytherapy in the management of cervical cancer.

Experimental Study on Phase Conjecture Based on Two-dimensional Image and Carrying Three-dimensional Image With Mist in Electro-holographic Reconstruction *

A method is proposed for phase conjecture based on the intensity curve of a two-dimensional(2D) image by computing a polynomial equation. The intensity values of the 2D image, which represents the distance between the image detectors and the three-dimensional(3D) scene is converted to phase information by our method. The results of numerical calculation with phase conjecture are analyzed. And what’s more, the numerical reconstruction results with phase information obtained as initial phase factors of a complex object for Fresnel kinoform and dynamic pseudorandom-phase tomographic computer holography(DPP-TCH) are compared. The peak signal-to-noise ratio(PSNR) and correlation coefficient (CC) between the reconstructed images and original object are analyzed. An experimental system is designed for photoelectric holographic reconstruction based on phase-only liquid crystal spatial light modulator(LC-SLM) and mist screen. The electro-optical experimental results indicate that suppressed the speckle noise 3D images that can be observed with naked eye have been obtained.

The method of repairing OHE damaged ancient painted murals based on machine vision

Traditional mural repair methods only observe the texture of murals when segmenting the repair area, but ignore the extraction of a mural damage data, resulting in incomplete damage crack information. For this reason, the method of repairing the damaged murals based on machine vision is studied. Using machine vision, it can get two-dimensional image of a mural, preprocess the image, extract the damaged data of a mural, and then divide the repair area and repair degree index. According to different types of damage, it can choose the corresponding repair methods to achieve the repair of damaged mural. The results show: Compared with the reference [1] method and reference [2] method, the number of repair points and repair cracks extracted by the proposed method is more than that of the two traditional methods, which can more accurately and comprehensively extract the repair information of murals.

Does intra-articular injection of adipose-derived stem cells improve cartilage mass? A case report using three-dimensional image analysis software in knee osteoarthritis

Background Mesenchymal stem cells are currently a research focus because of the possibility of cartilage regeneration through several mechanisms, including mesenchymal stem cell sheets. However, there are no published reports visualizing cartilage in three dimensions. Here, we report a case of improved cartilage volume. We purified and cultured adipose-derived mesenchymal stem cells and then performed adipose-derived mesenchymal stem cell therapy by directly injecting these cells into the articular cartilage. Cartilage was quantitatively evaluated before and after injection using three-dimensional image analysis software based on the magnetic resonance imaging. Case presentation The patient, a 55-year-old Japanese woman, experienced pain in both knees and was diagnosed with osteoarthritis of the knee. We performed adipose-derived mesenchymal stem cell therapy in both knees at our hospital and quantitatively evaluated cartilage before and after the treatment using the three-dimensional image analysis software “SYNAPSE VINCENT”. Conclusions Preoperatively, the cartilage defect area was 33.59 mm2 in the femur and 122.31 mm2 in the tibia; however, 12 months postoperatively, it improved to 13.59 mm2 and 51.43 mm2, respectively. Furthermore, the preoperative femur and tibia volumes were 9.58 mL and 3.82 mL, respectively; however, 12 months postoperatively, these values improved to 10.00 mL and 4.17 mL, respectively. For the quantitative analysis of cartilage, SYNAPSE VINCENT visualizes the state of cartilage in a high-definition three-dimensional image, which is excellent for understanding the state of the disease and explaining it to the patient. Although SYNAPSE VINCENT can only analyze the thickness of cartilage, and the reproducibility of the error is debatable, SYNAPSE VINCENT would be useful as a clinical tool for regenerative medicine. We have shown in this case report the promising effects of adipose-derived stem cell intraarticular injections in treating osteoarthritis and the use of new diagnostic instruments.

The Influence of 3-Dimensional Image Media to Improve Learning Outcomes of Social Studies Concepts With The Beauty of Togetherness Traditional Clothing Theme in

This study aims to determine the influence of 3-dimensional image media to improve learning outcomes of social studies concepts with beauty of togetherness traditional clothing theme in grade four at SDN Kaliwungu II, Jombang. This study uses a quantitative approach. - Posttest. The population in this study were all students of grade 4 at SDN Kaliwungu II, totaling 21 students. The problem in education is that the learning that is carried out is less attractive, meanwhile the educators are required to be creative in improving the quality of education such as using media in learning. The results of the study can be seen from the t test (paired t test) obtained t_count (6,3814) > t_table (2,0859.). The results of the research on the application of image media obtained 82%, which is very good. From these results, it can be stated that there is an effect of using 3- dimensional image media to improve learning outcomes of social studies concepts with beauty of togetherness traditional clothing theme in grade four at SDN Kaliwungu II, Jombang